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1780篇 您的检索式:作者名="FOX D"
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1最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL 2014神经病学与神经康复学杂志2014,11,3:31
2Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models显示文摘表示为基于 radiopharmaceutical 的成像为生物体之发光成像或 HSV1 thymidine kinase (HSV1-TK ) 编码任何一个萤火虫酶(fLuc ) 的记者 transgene 的 lentiviral 向量的二种新类型被构造监视人的胚胎的干细胞(hESC ) 在在移植以后的活老鼠的嫁接和增长。任何一个 transgene 的组成的表示没在文化改变 hESCs 的性质。我们下次在 SCID 鼠标监视了 teratomas 的形成到测试(1 ) 是否修改基因的 hESCs 维持他们的发展 pluripotency,并且(2 ) 是否支撑了记者基因表示,允许 noninvasive,在一个活鼠标模型的 hESC 衍生物的整个身体的成像。我们在接种以后从修改基因的房间以及野类型的 hESCs 2-4 月的两种类型观察了 teratoma 形成。用一个光成像系统,从 fLuc-transduced hESCs 的生物体之发光容易在在摸得出的肿瘤能被检测以前,长忍受 teratomas 的老鼠被检测。开发一个 noninvasive 成像方法对诊所更容易地可译,我们也利用了 HSV1-TK 和它的特定的底层, 1-(2 鈥 ? deoxy-2 鈥 ?fluoro- 尾 - D-arabinofuranosyl )-5-[125I]iodouracil ([125I ] FIAU ) ,记者 / 探查对。在全身的管理以后,[125I ] FIAU 是仅仅由编码 transgene 的 HSV1-TK 酶的 phosphorylated 并且在 transduced 以内保留(并且移植) 房间,由单个光子的排放允许敏感、量的成像计算了断层摄影术。象这些那样的 Noninvasive 成像方法可以使我们能在实时接受者以内重复地监视移植人的干细胞的存在和分发在上一通过记者基因的表达式长期。Martin G Pomper Holly Hammond Xiaobing Yu Zhaohui Ye Catherine A Foss Doris D Lin James J Fox Linzhao Cheng 2009Cell Research2009,19,3:9
3DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice显示文摘Meira Lisiane B Bugni James M Green Stephanie L Lee Chung-Wei Pang Bo Borenshtein Diana Rickman Barry H Rogers Arlin B Moroski-Erkul Catherine A McFaline Jose L Schauer David B Dedon Peter C Fox James G Samson Leona D 2008Journal of Clinical Investigation2008,,7:2
4Coating characteristics and tribological properties of sputterdeposited MoS2/metal composite coatings deposited by closed field unbalanced magnetron sputter ion plating显示文摘Renevier N M Fox V C Teer D G 2000Surface and Coatings Technology2000,127,:2
5MoS2/metal composite coating deposited by closed-field unbalanced magnetron sputtering: Tribological properties and industrial uses显示文摘Fox V Hampshire J Teer D 1999Surf Coat Technol1999,112,13:2
6Effects of Vedolizumab Induction Therapy for Patients With Crohn’s Disease in Whom Tumor Necrosis Factor Antagonist Treatment Had Failed显示文摘Bruce E. Sands Brian G. Feagan Paul Rutgeerts Jean-Frédéric Colombel William J. Sandborn Richmond Sy Geert D’Haens Shomron Ben-Horin Jing Xu Maria Rosario Irving Fox Asit Parikh Catherine Milch Stephen Hanauer 2014Gastroenterology2014,,:2
7Abdominal Visceral and Subcutaneous Adipose Tissue Compartments: Association With Metabolic Risk Factors in the Framingham Heart Study显示文摘Caroline S. Fox Joseph M. Massaro Udo Hoffmann Karla M. Pou Pal Maurovich-Horvat Chun-Yu Liu Ramachandran S. Vasan Joanne M. Murabito James B. Meigs L Adrienne Cupples Ralph B. D’Agostino Christopher J. O’Donnell 2007Circulation2007,,1:2
8Development of a PCR ELISA assay for the identification of Campylobacter jejuni and Campylobacter coli 显示文摘SAILS A D FOX A J BOLTON F J 2001Mol Cell Probe2001,15,:1
9Efficacy of me-mantine on behavioral and psychological symptoms related to dementia:a systematic meta-analysis显示文摘MAIDMENT I D FOX C G BOUSTANI M 2008Ann Pharmacother2008,42,1:1
10A real-time particle filters显示文摘Kwok C Fox D Meil M 2004Proceedings of the IEEE2004,92,3:1
11Adapting the sample size in particle filters through KLD-Sampling显示文摘FOX D 2003International Journal of Robotics Research2003,22,12:1
12Calcineurin regulatory subunit is essential for virulence and mediates interactions with FKBP12-FK506 in Cryptococcus neoformans显示文摘Fox D S Cruz M C Sia R A L 2001Molecular Microbiology2001,39,:1
13Fractal feature analysis and classification in medical imaging显示文摘CHEN Chi-chang Daponte J S Fox M D 1989IEEE Transactions on Medical Imaging1989,8,2:1
14Mitochondria genome a rearrangement leads to extension and relocation of the cytochrome C oxidase Subunit I gene in sorghum显示文摘Bailey Serres J Hanson D K Fox T D 1986Cell1986,47,:1
15Adapting the sample size in particle filters through KLDsampling 显示文摘Fox D 2003The International Journal of Robotics Research2003,22,12:1
16The timing of skin acidification in very low birth weight infants显示文摘Fox C Nelson D Wareham J 1998J Perinatol1998,18,4:1
17Prediction of ruminal volatile fatty acids and pH within the net carbohydrate and protein system显示文摘Pitt R E Van KesselJ S Fox D G 1996J Anita Sci1996,74,:1
18Wind tunnel evaluation of a computer program to model spray drift 显示文摘Zhu H Reichard D L Fox R D 1992Transactions of the ASAE1992,35,3:1
19A theoretical model of solar radiation transfer in a row-crop canopy显示文摘Yang X Shot T H Fox R D 1990Transaction of the ASAE1990,,33:1
20A function blocking abti-mouse integrin aipha5betal antibody inhibits angio- genesis and impedes tumor growth in vivo显示文摘Bhaskar V Zhang D Fox M 2007J Transl Med2007,5,:1
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