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| 1 | China’s first deep manned submersible,JIAOLONG显示文摘A deep manned submersible is indispensable to deep ocean exploration. No other equipment can bring scientists to ex-treme sea floor depths to do research in situ. Marine geology, seafloor geophysics,marine biology,and oceanic chemistry are the fields that scientists are particularly eager to study [1-6]. Chinese scientists have long dreamed of using their own submersible to probe the deep sea. China’s recent fast development of a deep manned submersible has realized that dream. | Liu, Feng Cui, WeiCheng Li, XiangYang | 2010 | Science China Earth Sciences2010，53，10： | 24 |
| 2 | Wnt and BMP signaling crosstalk in regulating dental stem cells:Implications in dental tissue engineering显示文摘Tooth is a complex hard tissue organ and consists of multiple cell types that are regulated by important signaling pathways such as Wnt and BMP signaling.Serious injuries and/or loss of tooth or periodontal tissues may significantly impact aesthetic appearance,essential oral functions and the quality of life.Regenerative dentistry holds great promise in treating oral/dental disorders.The past decade has witnessed a rapid expansion of our understanding of the biological features of dental stem cells,along with the signaling mechanisms governing stem cell self-renewal and differentiation.In this review,we first summarize the biological characteristics of seven types of dental stem cells,including dental pulp stem cells,stem cells from apical papilla,stem cells from human exfoliated deciduous teeth,dental follicle precursor cells,periodontal ligament stem cells,alveolar bone-derived mesenchymal stem cells(MSCs),and MSCs from gingiva.We then focus on how these stem cells are regulated by bone morphogenetic protein(BMP)and/or Wnt signaling by examining the interplays between these pathways.Lastly,we analyze the current status of dental tissue engineering strategies that utilize oral/dental stem cells by harnessing the interplays between BMP and Wnt pathways.We also highlight the challenges that must be addressed before the dental stem cells may reach any clinical applications.Thus,we can expect to witness significant progresses to be made in regenerative dentistry in the coming decade. | Fugui Zhang Jinlin Song Hongmei Zhang Enyi Huang Dongzhe Song Viktor Tollemar Jing Wang Jinhua Wang Maryam Mohammed Qiang Wei Jiaming Fan Junyi Liao Yulong Zou Feng Liu Xue Hu Xiangyang Qu Liqun Chen Xinyi Yu Hue H.Luu Michael J.Lee Tong-Chuan He Ping Ji | 2016 | Genes & Diseases2016，3，4： | 16 |
| 3 | Experimental and numerical study of failure behavior and mechanism of coal under dynamic compressive loads显示文摘A comprehensive understanding of the failure behavior and mechanism of coal is a prerequisite for dealing with dynamic problems in mining space.In this study,the failure behavior and mechanism of coal under uniaxial dynamic compressive loads were experimentally and numerically investigated.The experiments were conducted using a split Hopkinson pressure bar(SHPB)system.The results indicated that the typical failure of coal is lateral and axial at lower loading rates and totally smashed at higher loading rates.The further fractography analysis of lateral and axial fracture fragments indicated that the coal failure under dynamic compressive load is caused by tensile brittle fracture.In addition,the typical failure modes of coal under dynamic load were numerically reproduced.The numerical results indicated that the axial fracture is caused directly by the incident compressive stress wave and the lateral fracture is caused by the tensile stress wave reflected from the interface between coal specimen and transmitted bar.Potential application was further conducted to interpret dynamic problems in underground coal mine and it manifested that the lateral and axial fractures of coal constitute the parallel cracks in the coal mass under roof fall and blasting in mining space. | Junjun Feng Enyuan Wang Qisong Huang Houcheng Ding Xiangyang Zhang | 2020 | International Journal of Mining Science and Technology2020，30，5： | 13 |
| 4 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 5 | Effect of rare earth on the microstructure and mechanical properties of as-cast Cu-30Ni alloy显示文摘Cu-30Ni-xRE (x=0-0.213) alloys were prepared by a metal mould casting method. The effect of RE on the microstructure and mechanical properties of the alloys was investigated using optical microscope, scanning electronic microscope with energy-dispersive spectrometer, X-ray diffraction, and mechanical test. The results show that RE has obvious effect on refining dendrite structure and grain size, as well as on purifying the melting of Cu-30Ni alloy. With the increase of RE content, the ultimate tensile strength, yield strength, and elongation increase at first and then decrease after adding RE more than 0.095 wt.%. Cu-30Ni-0.095RE alloy possesses preferable mechanical properties, i.e., the ultimate tensile strength, yield strength, and elongation are 308 MPa, 125 MPa, and 51.2%, respectively. The microstructure and mechanical properties are worsened with increasing RE content more than 0.095 wt.%. The improvement of mechanical properties of Cu-30Ni-0.095RE alloy is attributed to RE refining microstructure and purifying the matrix. | MAO Xiangyang FANG Feng JIANG Jianqing TAN Rongsheng | 2009 | Rare Metals2009，28，6： | 9 |
| 6 | Concrete durability under different circumstances based on multi-factor effects显示文摘Concrete durability has become a hot research field in civil engineering. Concrete structures suffer salt-erosion damage to different degrees in the semi-arid region of North China. The environmental condition is one of the important factors affecting the durability of concrete constructions. To realize fully the interaction between various environmental factors, this paper researched concrete durability in the salt environment under combined actions(immersing, freeze–thaw cycles, and wet–dry cycles). According to the laboratory test data, the concrete-durability degradation law under coupling-effect factors was investigated. The results show that concrete's compressive strength decreases with the increase of salt concentration and immersion time. No matter what the environmental conditions were, the compressive strength-loss ratio increased with the test time. The compressive strength-test results indicate that sodium sulfate has the strongest corrosive effect on concrete durability, followed by calcium chloride, with sodium chloride having the weakest corrosion. Compared with the other two environmental factors, the wet–dry cycle is the key factor affecting concrete durability. Therefore, in engineering practice, the influence of environment conditions on the strength and durability of concrete should be taken into full consideration, especially in the wet–dry environment with salt conditions. | Feng Ming ChengCheng Du YuHang Liu XiangYang Shi DongQing Li | 2017 | Research in Cold and Arid Regions2017，9，4： | 6 |
| 7 | Core@shell sulfur@polypyrrole nanoparticles sandwiched in graphene sheets as cathode for lithium–sulfur batteries显示文摘A nano sulfur-based composite cathode material featured by uniform core@shell-structured sulfur@polypyrrole nanoparticles sandwiched in three-dimensional graphene sheets conductive network(S@PPy/GS) is fabricated via a facile solution-based method. The S@PPy nanoparticles are synthesized by in situ chemical oxidative polymerization of pyrrole on the surface of sulfur particles,and then graphene sheets are covered outside the S@PPy nanoparticles,forming a three-dimensional conductive network. When evaluating the electrochemical performance of S@PPy/GS in a lithium–sulfur battery,it delivers large discharge capacity,excellent cycle stability,and good rate capability. The initial discharge capacity is up to 1040 m Ah/g at 0.1 C,the capacity can remain 537.8 m Ah/g at 0.2 C after 200 cycles,even at a higher rate of 1 C,the specific capacity still reaches 566.5 m Ah/g. The good electrochemical performance is attributed to the unique structure of S@PPy/GS,which can not only provide an excellent transport of lithium and electron ions within the electrodes,but also retard the shuttle effect of soluble lithium polysulfides effectively,thus plays a positive role in building better lithium-sulfur batteries. | Xiangyang Zhou Feng Chen Juan Yang | 2015 | Journal of Energy Chemistry2015，24，4： | 3 |
| 8 | Microstructure, tensile properties and creep behavior of Al-12Si-3.5Cu-2Ni-0.8Mg alloy produced by different casting technologies显示文摘The relationship between the as-cast microstructure and mechanical properties of the Al-12 Si-3.5 Cu-2 Ni-0.8 Mg alloys produced by permanent mold casting(PMC) and high pressure die casting(HPDC)is investigated. The alloys in both PMC and HPDC consist of Al, Si, Al_5 Cu_2 Mg_8 Si_6, Al_3 Cu Ni, and Al_7 Cu_4 Ni phase. However, the microstructure of the HPDC alloy is significantly refined. Compared to the PMC alloy,the ultimate tensile strength of the HPDC alloy is significantly increased from 244 MPa to 310 MPa, while the elongation shows a reverse trend at room temperature. At low stress and temperature range, slight variations of stress exponent and activation energy indicate that the minimum creep rate is controlled by the grain boundary creep. Then the minimum creep rate is higher for the specimen with the smaller grain size, where grain boundary creep is the dominant creep mechanism. At high stress region, the stress exponent for the PMC alloy and HPDC alloy is 5.18 and 3.07, respectively. The different stress exponents and activation energies measured at high stress and high temperature range indicates that the creep mechanism varies with the casting technologies. | Lijie Zuo Bing Ye Jian Feng Xiangyang Kong Haiyan Jiang Wenjiang Ding | 2018 | Journal of Materials Science & Technology2018，34，7： | 3 |
| 9 | Muscle-fiber array inspired,multiple-mode,pneumatic artificial muscles through planar design and one-step rolling fabrication显示文摘Advances in development of artificial muscles have enabled creation of soft robots with biological dexterity and self-adaption in unstructured environments;however,production of scalable artificial muscles with multiple-mode actuations remains elusive.Inspired by muscle-fiber arrays in muscular hydrostats,we present a class of versatile artificial muscles called MAIPAMs(muscle-fiber array inspired pneumatic artificial muscles),capable of multiple-mode actuations(such as parallel elongation-bending-spiraling actuations,10 parallel bending actuations and cascaded elongation-bending-spiraling actuations).Our MAIPAMs consist of active 3D elastomer-balloon arrays reinforced by a passive elastomer membrane,achieved through a planar design and one-step rolling fabrication approach.We introduce prototypical designs for the MAIPAMs and demonstrate their muscle-mimic structures and versatility,as well as their scalable ability to integrate flexible but non-stretchable layers for contraction and twisting actuation modes and compliant electrodes for self-sensing.We further demonstrate that this class of artificial muscles shows potential for versatile robotic applications,such as carrying a camera for recording videos,gripping or manipulating objects,and climbing a pipe-line. | Jiang Zou Miao Feng Ningyuan Ding Peinan Yan Haipeng Xu Dezhi Yang Nicholas X.Fang Guoying Gu Xiangyang Zhu | 2021 | National Science Review2021，8，10： | 3 |
| 10 | Biogenic volatile organic compound emissions from leaves and fruits of apple and peach trees during fruit development显示文摘Biogenic volatile organic compounds(BVOCs)are widely involved in a variety of atmospheric chemical processes due to their high reactivity and species diversity.To date,however,research on BVOCs in agroecosystems,particularly fruit trees,remains scarce despite their large cultivation area and economic interest.BVOC emissions from different organs(leaf or fruit)of apple and peach trees were investigated throughout the stages of fruit development(FS,fruit swelling;FC,fruit coloration;FM,fruit maturity;and FP,fruit postharvest)using a proton-transfer-reaction mass spectrometer.Results indicated that methanol was the most abundant compound emitted by the leaf(apple tree leaf 492.5±47.9 ng/(g·hr),peach tree leaf 938.8±154.5 ng/(g·hr)),followed by acetic acid and green leaf volatiles.Beside the above three compounds,acetaldehyde had an important contribution to the emissions from the fruit.Overall,the total BVOCs(sum of eight compounds studied in this paper)emitted by both leaf and fruit gradually decreased along the fruit development,although the effect was significant only for the leaf.The leaf(2020.8±258.8 ng/(g·hr))was a stronger BVOC emitter than the fruit(146.0±45.7 ng/(g·hr))(P=0.006),and there were no significant differences in total BVOC emission rates between apple and peach trees.These findings contribute to our understanding on BVOC emissions from different plant organs and provide important insights into the variation of BVOC emissions across different fruit developmental stages. | Shuangjiang Li Xiangyang Yuan Yan Xu Zhengzhen Li Zhaozhong Feng Xu Yue Elena Paoletti | 2021 | Journal of Environmental Sciences2021，33，10： | 2 |
| 11 | Visualizing large-scale high-dimensional data via hierarchical embedding of KNN graphs显示文摘Visualizing intrinsic structures of high-dimensional data is an essential task in data analysis.Over the past decades,a large number of methods have been proposed.Among all solutions,one promising way for enabling effective visual exploration is to construct a k-nearest neighbor(KNN)graph and visualize the graph in a low-dimensional space.Yet,state-of-the-art methods such as the LargeVis still suffer from two main problems when applied to large-scale data:(1)they may produce unappealing visualizations due to the non-convexity of the cost function;(2)visualizing the KNN graph is still time-consuming.In this work,we propose a novel visualization algorithm that leverages a multilevel representation to achieve a high-quality graph layout and employs a cluster-based approximation scheme to accelerate the KNN graph layout.Experiments on various large-scale datasets indicate that our approach achieves a speedup by a factor of five for KNN graph visualization compared to LargeVis and yields aesthetically pleasing visualization results. | Haiyang Zhu Minfeng Zhu Yingchaojie Feng Deng Cai Yuanzhe Hu Shilong Wu Xiangyang Wu Wei Chen | 2021 | Visual Informatics2021，5，2： | 2 |
| 12 | Thermal Evolution of Plutons and Uplift Process of the Yanshan Orogenic Belt显示文摘Thermochronological dating was used to study the thermal evolution of the Mesozoic plutons and uplift history of the Yanshan orogenic belt. The results show that the cooling history of the plutons is complicated, corresponding to the inhomogeneous uplift process of the Yanshan orogenic belt. The Panshan granite cooled fast during 226.48-204.95 Ma at a rate of 10.22℃/Ma after its emplacement at a depth of about 10 km, and its fast uplift occurred in about 96-35 Ma at an average rate of 0.115 mm/a. The Wulingshan pluton cooled fast during 132-127.23 Ma at a rate of 94.34℃/Ma, and its rapid uplift occurred in 86-45 Ma at an average rate of 0.186 mm/a. The Yunmengshan granite cooled fast during 143-120.99 Ma at a rate of 19.51℃/Ma, and its rapid uplift occurred in 106-103.95 Ma and 20-0.0 Ma at a rate of 1.06 mm/a and 0.15 mm/a respectively. The Sihetang granite-gneiss uplifted rapidly since 13 Ma at an average rate of 0.256 mm/a. The Badaling granite uplifted rapidly since 6 Ma at an average rate of 0. | WU Zhenhan CUI Shengqin ZHU Dagang FENG Xiangyang MA Yinsheng | 2000 | Acta Geologica Sinica(English Edition)2000，74，1： | 2 |
| 13 | Elastic anisotropy and its influencing factors in organic-rich marine shale of southern China显示文摘Shale is observed to have strong anisotropy due to its unique mineralogy and microstructure, and this anisotropy property has significant impact on seismic and well-log data. The organic-rich marine shale in the southern and eastern Sichuan Basin is one of the most important shale-gas reservoir formations in China. To investigate the elastic anisotropy of this shale and its influencing factors, we performed ultrasonic velocity measurements, X-ray diffraction analysis, rock-eval pyrolysis and vitrinite reflectance measurement on the samples from the Upper Ordovician Wufeng Formation and the Lower Silurian Longmaxi Formation. The experimental results show the that:(1) the velocity anisotropy of the Wufeng-Longmaxi(WL) shale varies from 10% to 50%, and most samples have strong anisotropy;(2) the P-and S-wave anisotropy parameters(Thomsen's εand γ) increase with clay contents, but this relationship can be greatly affected by the clay orientation index;(3) organic matter content(OMC) is found to have little influence in seismic anisotropy for the over mature WL shale, whereas the OMC determines the magnitude of anisotropy of immature/mature shales(e.g. the Bakken shale or the Bazhenov shale) according to the published literatures, because organic matters in shales of different maturity have different morphologies and distributions;(4) the OMC of WL shale has positive correlation with quartz content, and this weakens the correlation between OMC and the magnitude of anisotropy to a certain extent. The results of this study provide an important rock-physics basis and data support for seismic anisotropy exploration, quantitative interpretation and resource evaluation of the organic-rich marine shales in southern China. | Zichun LIU Feng ZHANG Xiangyang LI | 2019 | Science China Earth Sciences2019，62，11： | 2 |
| 14 | Joint association analysis method to dissect complex genetic architecture of multiple genetically related traits显示文摘Genome-wide association study(GWAS)has been a standard approach to discover the genetic determinants underlying complex traits.It is a major challenge in GWAS how to improve analysis power,uncover complex genetic correlation,and reveal gene-gene and gene-environment interactions through integrated analysis of multiple genetically related traits.To combat these challenges,we proposed a mixed linear model-based joint association analysis method for multiple traits,which include epistasis and geneenvironment interaction in the mapping model and utilize within-trait variance and between-trait covariance simultaneously;A F-statistics based on Wilks statistics is used to test the significance of each SNP and paired interacted SNPs,each genetic effects of QTS are estimated and tested by the MCMC method based on a QTS full model.Simulations showed that the multi-trait GWAS method could provide increased power in detecting pleiotropic loci affecting more than one trait,and can unbiasedly estimate effects of QTS.To demonstrate the performance of the proposed method,we analyzed four blood lipid traits in Multi-Ethnic Study of Atherosclerosis(MESA)Cohort and two yield-related traits in a rice immortalized F2 dataset.A software package was developed for the proposed method. | Feng Lin Guoan Qi Ting Xu Xiangyang Lou Yongbo Hong Haiming Xu | 2020 | The Crop Journal2020，8，5： | 2 |
| 15 | Exact elastic impedance tensor for isotropic media显示文摘The existing expressions of elastic impedance,as the generalized form of acoustic impedance,represent the resistance of subsurface media to seismic waves of non-normal incidence,and thus include information on the shear-wave velocity.In this sense,conventional elastic impedance is an attribute of the seismic reflection and not an intrinsic physical property of the subsurface media.The derivation of these expressions shares the approximations made for reflectivity,such as weak impedance contrast andisotropic or weakly anisotropic media,which limits the accuracy of reflectivity reconstruction and seismic inversion.In this paper,we derive exact elastic impedance tensors of seismic P-and S-waves for isotropic media based on the stress-velocity law.Each componentof the impedance tensor represents a unique mechanical property of the medium.Approximations of P-wave elastic impedance tensor components are discussed for seismic inversion and interpretation.Application to synthetic data and real data shows the accuracy and robust interpretation capability of the derived elastic impedance in lithology characterizations. | ZHANG Feng LI XiangYang | 2015 | Science China Earth Sciences2015，58，8： | 2 |
| 16 | Purification, characterization and immunomodulating activity of a polysaccharide from flowers of Abelmoschus esculentus显示文摘 | Wei Zheng Ting Zhao Weiwei Feng Wei Wang Ye Zou Daheng Zheng Mohammed Takase Qian Li Huiyu Wu Liuqing Yang Xiangyang Wu | 2014 | Carbohydrate Polymers2014，，： | 1 |
| 17 | Surgical Treatment and Prognosis of Synchronous Double Primary Lung Cancer: a Report of 31 Cases显示文摘 | Feiyue Feng Dechao Zhang Xiangyang Liu Yonggang Wang Yousheng Mao | 2005 | Chinese Journal of Clinical Oncology2005，2，5： | 1 |
| 18 | Enhanced biological nitrogen removal via dissolved oxygen partitioning and step feeding in a simulated river bioreactor for contaminated source water remediation 显示文摘 | FENG Lijuan XU Jian XU Xiangyang | 2012 | International Biodeterioration & Biodegradation2012，71，： | 1 |
| 19 | Rheological be harlots of nylon 6/silica modified melamine cyanurate non-halo gen flame retardant composites显示文摘 | Wei Shanshan Yao Feng Xu Xiangyang | 2013 | Journal of Nanoseience and Nanotechnology2013，13，3： | 1 |
| 20 | Application Studies of Methods of Discriminant and Cluster in TCM Acupuncture Clinical Data Analysis显示文摘 | Xiangyang Feng Youqun Shi Qinfeng Huang | 2013 | 1(14):133-1342013，1，14： | 1 |
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