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| 1 | Alcohol consumption on pancreatic diseases显示文摘Although the association between alcohol and pancreatic diseases has been recognized for a long time,the impact of alcohol consumption on pancreatitis and pancreatic cancer(PC)remains poorly defined.Nowadays there is not consensus about the epidemiology and the beverage type,dose and duration of alcohol consumption causing these diseases.The objective of this study was to review the epidemiology described in the literature for pancreatic diseases as a consequence of alcoholic behavior trying to understand the association between dose,type and frequency of alcohol consumption and risk of pancreatitis and PC.The majority of the studies conclude that high alcohol intake was associated with a higher risk of pancreatitis(around 2.5%-3% between heavy drinkers and 1.3%between non drinkers).About 70%of pancreatitis are due to chronic heavy alcohol consumption.Although this incidence rate differs between countries,it is clear that the risk of developing pancreatitis increases with increasing doses of alcohol and the average of alcohol consumption vary since 80 to 150 g/d for 10-15 years.With regard to PC, the role of alcohol consumption remains less clear,and low to moderate alcohol consumption do not appear to be associated with PC risk,and only chronic heavy drinking increase the risk compared with lightly drinkers.In a population of 10%-15%of heavy drinkers, 2%-5%of all PC cases could be attributed to alcohol consumption.However,as only a minority(less than 10%for pancreatitis and 5%for PC)of heavily drinkers develops these pancreatic diseases,there are other predisposing factors besides alcohol involved.Genetic variability and environmental exposures such as smoking and diet modify the risk and should be considered for further investigations. | Marta Herreros-Villanueva Elizabeth Hijona Jesus Maria Baales Angel Cosme Luis Bujanda | 2013 | World Journal of Gastroenterology2013，19，5： | 3 |
| 2 | Evaluation of ultrahigh temperature ceramics for aero- propulsion use显示文摘 | STANLEY R L ELIZABETH J O MICHAEL C H et al | 2002 | Journal of the European Ceramic Society2002，22，： | 1 |
| 3 | Stress,immune reactivity and susceptibility to infectious disease显示文摘 | Marslanda AL Elizabeth A Bachenb EA et a1 | 2002 | Physiology & Behavior2002，，77： | 1 |
| 4 | Three-Color, Solid-State, Three- Dimensional Display显示文摘 | Elizabeth Downing al et | 1996 | Science1996，，273： | 1 |
| 5 | The impor-tance of early parenting in at-risk families and children's so-cial-emotional adaptation to school显示文摘 | Elizabeth McFarlane Rachel ABD Lori B et aL | 2010 | Acad Pediatr2010，10，5： | 1 |
| 6 | Increased model for end‐stage liver disease score at the time of liver transplant results in prolonged hospitalization and overall intensive care unit costs显示文摘 | Matthew R. Foxton Mohammad A. B. Al‐Freah Andrew J. Portal Elizabeth Sizer William Bernal Georg Auzinger Mohamed Rela Julia A. Wendon Nigel D. Heaton John G. O’Grady Michael A. Heneghan | 2010 | Liver Transpl2010，，5： | 1 |
| 7 | CD36 expression and lipid metabolism following an oral glucose challenge in South Asians显示文摘AIM:To investigate lipid metabolism and the relationship with monocyte expression of the fatty acid translocase CD36 in South Asians.METHODS:An observational study of South Asians whom as an ethnic group have-a higher risk of developing diabetes.The susceptibility to diabetes is coupled with an earlier and more rapid progression of micro-,and macro-vascular complications.Twentynine healthy South Asian participants [mean age 34.6(8.9) years,76.2% male,mean body-mass index 25.0(5.2) kg/m2] were recruited from an urban residential area of central Birmingham(United Kingdom).The main outcomes measured were post prandial(30 min) and post absorptive(120 min) changes from fasting(0 min) in circulating lipoproteins,lipds and hormones,andmonocyte expression of CD36 post injection of a 75 g oral glucose challenge.The inducements of variations of monocyte CD36 expression were analysed.RESULTS:Our results showed evident changes in monocyte CD36 expression following the glucose challenge(P < 0.001).Non-esterified fatty acids(NEFA) levels decreased progressively during the challenge(P < 0.001),in contrast to increased cholesterol(but not triglyceride) concentrations within very low density lipoprotein(VLDL) and low density lipoprotein subfractions(P < 0.01).Levels of,glucose,serum triglycerides and high density lipoprotein cholesterol remained largely unchanged.Variations of monocyte CD36 were negatively(r =-0.47,P = 0.04) associated to fat from the diet and positively to carbohydrate from the diet(r = 0.65,P < 0.001).CONCLUSION:These data suggest that the initiation of VLDL genesis follows the consumption of glucose within this population,inferring that the sequestration of NEFA from these particles happens due to the increased availability of CD36 receptors.While these are preliminary results,it would appear that lifestyle exposures have a role in moderating the expression of CD36. | Jeetesh V Patel Amitava Banerjee Silvia Montoro-Garcia Eduard Shantsila Mushfique Alam Paul Flinders Kathleen AL Houlton Elizabeth A Hughes Gregory YH Lip Paramjit S Gill | 2015 | World Journal of Diabetes2015，6，7： | 1 |
| 8 | Retronasal and orthonasal olfactory ability after laryngectomy显示文摘 | Elizabeth AL Frank A John W | 2007 | Arch Otolaryngol Head Neck Surg2007，133，1： | 1 |
| 9 | Comparative onset of action and symptom relief with cetirizine, loratadin or placebo in an environmental exposure unit in subjects with seasonal allergic rhinifis: confirmation of a test system 显示文摘 | James H Day Maureen Briscoe Elizabeth Rafeiro at al | 2001 | Annals of Allergy Asthma&Immunology2001，87，11： | 1 |
| 10 | Flap thickness accuracy显示文摘 | Kerry D Solomon Eric Donnenfeld Helga P Sandoval Oday Al Sarraf Terrance J Kasper Mike P Holzer Elizabeth H Slate David T Vroman Flap Thickness Study Group | 2004 | Journal of Cataract & Refractive Surgery2004，，5： | 1 |
| 11 | Organometallic diphenols:T he importan-ce of the organometallic moiety on the expression of a cytotoxic effect on breast cancer cells显示文摘 | Elizabeth A Hillard Anne Vessi~res t al | 2007 | Journal of Organometalli c Chemistry2007，692，6： | 1 |
| 12 | Molecular control of vertebrate iron homeostasis by iron regulatory proteins 显示文摘 | Michelle LW Elizabeth AL Richard SE | 2006 | Biochimica et Biophysica Acta2006，1763，7： | 1 |
| 13 | Evaluation of Cir- culating Tumor Cells and Circulating Tumor DNAin Non-Small Cell Lung Cancer:Association with Clinical Endpoints in a Phase II Clinial Trial of Pertuzumab and Erlotinib显示文摘 | Elizabeth A Punnoose Siminder Atwal ^ al | 2012 | Clin Cancer Res2012，18，： | 1 |
| 14 | Epidemiology of Sudden Cardiac Death: Clinical and Research Implications显示文摘 | Sumeet S. Chugh Kyndaron Reinier Carmen Teodorescu Audrey Evanado Elizabeth Kehr Mershed Al Samara Ronald Mariani Karen Gunson Jonathan Jui | 2008 | Progress in Cardiovascular Diseases2008，，3： | 1 |
| 15 | Human gut‐specific homeostatic dendritic cells are generated from blood precursors by the gut microenvironment显示文摘 | Elizabeth R. Mann David Bernardo Hafid Omar Al‐Hassi Nicholas R. English Susan K. Clark Neil E. McCarthy Andrew N. Milestone Stella A. Cochrane Ailsa L. Hart Andrew J. Stagg Stella C. Knight | 2011 | Inflamm Bowel Dis2011，，7： | 1 |
| 16 | Detection ofrespiratory syncytial virus using nanoparticle amplified immuno-polymerase chain reaction 显示文摘 | Jonas W P Elizabeth A V Patricia K H eL al | 2011 | Analytical Biochemislry2011，410，1： | 1 |
| 17 | Hypoxia Posttranslationally Activates Iron-regulatory Protein 2显示文摘 | Erics SH Laura MF Elizabeth AL | 1999 | J Biol Chem1999，274，8： | 1 |
| 18 | Neural structures underly- ing set-shifting: Roles of medial prefrontal cortex and anterior cingu- late cortex显示文摘 | Gregory B Elizabeth M Matthew R et al | 2013 | Behavioural Brain Research2013，250，： | 1 |
| 19 | Influence of 10 wk of soy consumption on plasma concentrations and excretion of isoflavonoids and on gut microflora metabolism in healthy adults显示文摘 | Helen Wiseman Karen Casey Elizabeth A Bowey el al | 2004 | Am J Clin nutr2004，80，： | 1 |
| 20 | Environmental fluctuations induce scale-dependent compensation and increase stability in plankton ecosystems 显示文摘 | Dowing AL Bryan LB Elizabeth MP Timothy HK Mathew AL | 2008 | Ecology2008，89，11： | 1 |
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