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| 1 | Diagnostic yield of small bowel capsule endoscopy depends on the small bowel transit time显示文摘AIM:To investigate whether the small bowel transit time(SBTT)influences the diagnostic yield of capsule endoscopy(CE).METHODS:Six hundred and ninety-one consecutive CE procedures collected in a database were analyzed.SBTT and CE findings were recorded.A running mean for the SBTT was calculated and correlated to the diagnostic yield with a Spearman's correlation test.Subgroup analyses were performed for the various indications for the procedure.RESULTS:There was a positive correlation between the diagnostic yield and SBTT(Spearman's rho 0.58,P <0.01).Positive correlations between diagnostic yield and SBTT were found for the indication obscure gastrointestinal bleeding(r=0.54,P<0.01),for polyposis and carcinoid combined(r=0.56,P<0.01)and for the other indications(r=0.90,P<0.01),but not for suspected Crohn's disease(r=-0.40).CONCLUSION:The diagnostic yield in small bowel capsule endoscopy is positively correlated with the small bowel transit time.This is true for all indications except for suspected Crohn's disease. | Jessie Westerhof Jan J Koornstra Reinier A Hoedemaker Wim J Sluiter Jan H Kleibeuker Rinse K Weersma | 2012 | World Journal of Gastroenterology2012,18,13: | 10 |
| 2 | Long noncoding RNA in cardiac aging and disease显示文摘Cardiovascular diseases(CVDs)are the main cause of morbidity and mortality in Western society and present an important agerelated risk.With the constant rise in life expectancy,prevalence ofCVD in the population will likely increase further.New therapies,especially in the elderly,are needed to combat CVD.This review is focused on the role of long noncoding RNA(IncRNA)in CVD.RNA sequencing experiments in the past decade showed that most RNA does not code for protein,but many RNAs function as ncRNA.Here,we summarize the recent findings of IncRNA regulation in the diseased heart.The potential use of these RNAs as biomarkers of cardiac disease prediction is also discussed. | Noelia Lozano-Vidal Diewertje IBink Reinier A.Boon | 2019 | Journal of Molecular Cell Biology2019,11,10: | 5 |
| 3 | Specific and cross-reactive immune response against Mycobacterium tuberculosis antigens in mice immunized with proteoliposomes from Mycobacterium bovis BCG显示文摘Objective: To characterize the immunogenicity and the induction of cross-reactive responses against Mycobacterium tuberculosis(M. tuberculosis) of a proteoliposome(PL)from Mycobacterium bovis Bacillus Calmette–Guerin(BCG) with and without alum hydroxide(AL) as adjuvant(PLBCG-AL and PLBCG, respectively) in BALB/c mice.Methods: BALB/c mice were inoculated with phosphate buffer solution, BCG, PLBCG and PLBCG-AL. The humoral immunogenicity was determined by ELISA [immunoglobulin G(Ig G), Ig G1 and Ig G2a] and the cellular immunogenicity was evaluated in vivo by delayed type hypersensitivity. The humoral cross-reactive response against M. tuberculosis was determined by Western blot.Results: Sera from animals immunized with PLBCG-AL and PLBCG showed significant increase in specific total Ig G and Ig G1 antibodies and the presence of cross-reactive antibodies against M. tuberculosis antigens, which were more intense with the use of alum as adjuvant. Mice immunized with PLBCG and PLBCG-AL also showed a specific cellular response in vivo.Conclusions: The cellular and humoral immunogenicity of PLBCG and the capacity to induce cross-reactive responses against M. tuberculosis is in agreement with the protective capacity previously demonstrated by this vaccine candidate and supports the continuation of its evaluation in further stages. | Nadine Alvarez DaymíSerpa Ramlah Kadir Yanely Tirado Reinier Borrero Sonsire Fernández Rubén Cabrera Yolanda Valdes Caridad Zayas Reinaldo Acevedo Luis Izquierdo María Elena Sarmiento Mohd-Nor Norazmi JoséLuis Pérez Armando Acosta | 2017 | Asian Pacific Journal of Tropical Biomedicine2017,7,3: | 3 |
| 4 | Sympathetic innervation of the liver in man and dog: An immunohistochemical study显示文摘 | Reinier Mann B Appl Sci Prithi S. Bhathal MBBS PhD Christopher Bell | 1991 | Clinical Autonomic Research1991,,2: | 2 |
| 5 | Prolonged Tpeak -to -tend interval on the resting ECG isassociated with increased risk of sudden cardiac death 显示文摘 | PANIKKATH R REINIER K UY-EVANADO A | 2011 | CircArrhythm Electrophysiol2011,4,4: | 1 |
| 6 | Mechanics of toe and heel landing in stepping down in ongoing gait显示文摘 | Jaap H Marcel S Reinier K | 2008 | Physical Therapy in Sport2008,41,: | 1 |
| 7 | Independent contribution of diabetes to increased prevalence and incidence of atrial fibrillation显示文摘 | Nichols GA Reinier K Chugh SS | | 0,,10: | 1 |
| 8 | Human Placenta Is a Potent Hematopoietic Niche Containing Hematopoietic Stem and Progenitor Cells throughout Development显示文摘 | Catherine Robin Karine Bollerot Sandra Mendes Esther Haak Mihaela Crisan Francesco Cerisoli Ivoune Lauw Polynikis Kaimakis Ruud Jorna Mark Vermeulen Manfred Kayser Reinier van der Linden Parisa Imanirad Monique Verstegen Humaira Nawaz-Yousaf Natalie Papaz | 2009 | Cell Stem Cell2009,,: | 1 |
| 9 | A Self-En forcing Model o f Corporate law 显示文摘 | Black Bernard and Reinier Kraakman | 1911 | Harvard law Review 1091911,1996,: | 1 |
| 10 | Prolonged Tpeak-to-tend interval on the resting ECG is associated with increased riskof sudden cardiac death显示文摘 | Panikkath R Reinier K Uy-Evanado A | 2011 | Circ Arrhythm Electrophysiol2011,4,4: | 1 |
| 11 | Determinants of prolonged QT interval and their contribution to sudden death risk in coronary artery disease:the Oregon Sudden Unexpected Death Study显示文摘 | Chugh SS Reinier K Singh T | 2009 | Circulation2009,119,5: | 1 |
| 12 | Epidemiology of Sudden Cardiac Death:Clinical and Research Implications显示文摘 | Chugh SS Reinier K Teodorescu C | 2008 | Prog Cardiovasc Dis2008,51,3: | 1 |
| 13 | What is orbital pseudotumor?显示文摘 | Ilse Mombaerts Roel Goldschmeding Reinier O. Schlingemann Leo Koornneef | 1996 | Survey of Ophthalmology1996,,: | 1 |
| 14 | Common variants in CA SQ2, GPD1L, and NOSIA P are significantly associated with risk of sudden death in patients with coronary artery disease显示文摘 | Westaway SK Reinier K Huertas-Vazquez A et ol | 2011 | Circ Car- diovasc Genet2011,4,4: | 1 |
| 15 | 企业演变史显示文摘过去三十年中,企业组织形态的发展结合了传统合伙上的契约自由和传统公司上的债权人权利模式。法学者对这类新的组织形态更像合伙还是更像公司各持己见。持更类似合伙观点的人认为契约自由的程度是传统公司和合伙形式的本质区别,而持相反见解的学者则认为债权人权利模式才是区别之关键。本文作者赞同后者。我们通过检视企业实体演变的过程来揭示:公司中传统刚性规则对债权人权利保护有重要作用,但是随着保护投资者的替代制度的发展,公司对刚性规则的需求日衰,而对契约自由的需求则日盛。本文中,作者首先讨论了企业实体演变的历史,侧重于讨论债权人保护在演变中的主要作用。随后,作者认为,尽管在讨论债权人保护以及公司与合伙的区别时,法学者总是将注意力放在有限责任上,但区别公司与合伙的主要特征在于'人格屏蔽'——指将公司财产分配给享有不同权利的不同类型债权人。在讨论强的人格屏蔽的重要性——公司而非合伙的特征——以及该制度如何完善有限责任之后,作者得出结论:新的企业组织形态是强的人格屏蔽扩展到受较少限制的企业实体的过程的产物,因此新的组织形态应视为公司的衍生而非合伙。 | Henry Hansmann Reinier Kraakman Richard Squire 谭津龙 | 2009 | 研究生法学2009,,2: | 1 |
| 16 | Independent Contribution of Diabetes to Increased Prevalence and Incidence of Atrial Fibrillation显示文摘 | Nichols Gregory A Reinier Kyndaron Chugh Sumeet S | 2009 | Diabetes Care2009,,: | 1 |
| 17 | Epidemi- ology of sudden cardiac death:Clinical and research implications 显示文摘 | CHUGH S S REINIER K TEODORESCU C | 2008 | Prog Cardiovasc Dis2008,51,3: | 1 |
| 18 | Intercellular Transport of MicroRNAs显示文摘 | Reinier A. Boon Kasey C. Vickers | 2013 | Arteriosclerosis, Thrombosis, and Vascular Biology2013,,: | 1 |
| 19 | Epidemiology of sudden cardiac death:clinical and research implications显示文摘 | Chugh SS Reinier K Teodorescu C | 2008 | Prog Cardiovasc Dis2008,51,3: | 1 |
| 20 | Amphibians and agricultural chemicals:Review of the risks in a complex environment显示文摘 | Reinier M Mann R V H Catherine B C | | 0,,: | 1 |