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| 1 | The role of MDM2 and MDM4 in breast cancer development and prevention显示文摘从乳癌的死亡的主要原因不是主要的瘤,而是 relapsing,药抵抗的、变形疾病。识别贡献好攻击的癌症的因素为治疗提供重要领先。对致癌物的固有的防卫取决于每个人的单个分子的组成。这些回答的重要分子的决定因素在鼠标的控制下面是两倍分钟(MDM ) 家庭:蛋白质 MDM2 和 MDM4 包括了。对应力和随后的恢复的在正常、健康成年房间,极其调整的 MDM 家庭功能测量的、细胞的回答。MDM 家庭的合适的功能为正常的胸开发,而且为保存 genomic 忠实是重要的。MDM 家庭成员最好被描绘让他们主要的瘤 suppressor p53 的否定规定调制压力回答。他们另外的细胞的管理者上的影响正在出现。MDM 家庭的不适当地提高的蛋白质层次高度与癌症发生的增加的风险被联系。是的 MDM 家庭成员的探索癌症治疗学的目标为设计定制的反癌症治疗是相关的,但是成功的途径必须战略上在目标癌症和邻近的健康房间和纸巾上考虑影响。这评论集中于在正常、恶意的胸房间与 MDM 家庭的角色相关的最近的调查结果。 | Sue Haupt Reshma Vijayakumaran Panimaya Jeffreena Miranda Andrew Burgess Elgene Lim Ygal Haup | 2017 | Journal of Molecular Cell Biology2017，9，1： | 3 |
| 2 | Effects of thermal treatmenls on five different waste activated sludge sam- pies solubilisation,physical properties and anaerobic di- gestion 显示文摘 | Bougrier C l)elgenes J P Carr re H | 2008 | Chem Eng J2008，139，2： | 1 |
| 3 | Pre-operative radiotherapy prolongs survival in operable esophageal carcinoma: A randomized, multicenter study of pre-operative radiotherapy and chemotherapy. The second scandinavian trial in esophageal cancer显示文摘 | Knut Nygaard M.D. Steinar Hagen M.D. Hanne Sand Hansen M.D. Reidulv Hatlevoll M.D. Ragnar Hultborn M.D. Anders Jakobsen M.D. Matti M?ntyla M.D. Hans Modig M.D. Eva Munck-Wikland M.D. Bengt Rosengren M.D. Johan Tausj? M.D. Kjell Elgen | 1992 | World Journal of Surgery1992，，6： | 1 |
| 4 | Low birth weight young adults: quality of life, academic achievements and social functioning 显示文摘 | Odberg MD Elgen IB | 2011 | Acta Paediatr2011，100，2： | 1 |
| 5 | Pre-operative radiotherapy prolongs survival in operable esophageal carcinoma: A randomized, multicenter study of pre-operative radiotherapy and chemotherapy. The second scandinavian trial in esophageal cancer显示文摘 | Knut Nygaard M.D. Steinar Hagen M.D. Hanne Sand Hansen M.D. Reidulv Hatlevoll M.D. Ragnar Hultborn M.D. Anders Jakobsen M.D. Matti M?ntyla M.D. Hans Modig M.D. Eva Munck-Wikland M.D. Bengt Rosengren M.D. Johan Tausj? M.D. Kjell Elgen | 1992 | World Journal of Surgery1992，，6： | 1 |
| 6 | Factors determining distributions of tree species and plant functional types显示文摘 | Elgene O. Box | 1995 | Vegetatio (-)1995，，1： | 1 |
| 7 | Targeting Androgen Receptor in Estrogen Receptor-Negative Breast Cancer显示文摘 | Min Ni Yiwen Chen Elgene Lim Hallie Wimberly Shannon T. Bailey Yuuki Imai David L. Rimm X. Shirley Liu Myles Brown | 2011 | Cancer Cell2011，，1： | 1 |
| 8 | The RasGAP Gene, RASAL2 , Is a Tumor and Metastasis Suppressor显示文摘 | Sara Koenig McLaughlin Sarah Naomi Olsen Benjamin Dake Thomas De Raedt Elgene Lim Roderick Terry Bronson Rameen Beroukhim Kornelia Polyak Myles Brown Charlotte Kuperwasser Karen Cichowski | 2013 | Cancer Cell2013，，3： | 1 |
| 9 | Factors determining distributions of tree species and plant functional types显示文摘 | Elgene O. Box | 1995 | Vegetatio (-)1995，，1： | 1 |
| 10 | Emotional and behavioural problems in subgroups of children with chronic illness : resuhs from a large-scale population study 显示文摘 | Hysing M Elgen I Gillberg C | 2009 | Child Care Health Dev2009，35，4： | 1 |
| 11 | Geographical dimensions of terrestrial net and gross primary productivity显示文摘 | Elgene Box | 1978 | Radiation and Environmental Biophysics1978，，4： | 1 |
| 12 | SBR as a relevant technology to combine anaerobic digestion and nitrification in a single reactor显示文摘 | BERNET N D ELGENES J P MOLETTA R D | 2001 | Water Science and Technology2001，43，3： | 1 |
| 13 | Cognitive performance in a low birth weight cohort at 5 and 11 years of age显示文摘 | Elgen I Sommerfelt K and Ellertsen B | 2003 | Pediatr Neurol2003，29，2： | 1 |
| 14 | Low birth weight young adults:quali-ty of life, academic achievements and social functioning显示文摘 | Odberg MD Elgen IB | 2011 | Acta Paediatr2011，100，2： | 1 |
| 15 | Global classification of natural terrestrial ecosystems显示文摘 | Heinrich Walter Elgene Box | 1976 | Vegetatio1976，，2： | 1 |
| 16 | Triple combination targeting PI3K,ER,and CDK4/6 inhibits growth of ER-positive breast cancer resistant to fulvestrant and CDK4/6 or PI3K inhibitor显示文摘Dear Editor,Despite the improved outcome of advanced estrogen receptor-positive(ER+)breast cancer patients treated with endocrine therapy in combination with either a cyclindependent kinase 4/6 inhibitor(CDK4/6i)or a phosphoinositide 3-kinase inhibitor(PI3Ki),the disease will eventually progress,and the optimal treatment strategy upon progression remains undefined[1-4].To address this,we developed MCF-7-and T47D-derived PIK3CAmutated breast cancer cell lines[5]resistant to combined CDK4/6i palbociclib and fulvestrant(MPF-R and TPFR)or combined PI3Ki alpelisib and fulvestrant(MAF-R and TAF-R),respectively(Supplementary Materials and Methods).Drug-sensitive isogenic cells(M-S and T-S)grown in parallel with MPF-R and TPF-R cells and the original MCF-7/S0.5 and T47D cells were analyzed for comparison. | Mikkel G.Terp Martina Tuttolomondo Neil Portman Sidse Ehmsen Lene E.Johansen Martin Bak Elgene Lim Henrik J.Ditzel | 2023 | Cancer Communications2023，43，6： | 0 |
| 17 | 低出生体重儿的一个无缺陷队列在11岁时的生长发育和一般健康状况 | Elgen I. Johansson K.A. Markestad T. Sommerfelt K. 郭战宏 | 2006 | 世界核心医学期刊文摘(儿科学分册)2006，0，A03： | 0 |
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