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31篇 您的检索式:作者名="Dingding LI"
    题名 作者 年代 出处 被引量
1Expression changes and bioinformatic analysis of Wallerian degeneration after sciatic nerve injury in rat显示文摘Wallerian degeneration (WD) remains an important research topic. Many genes are differentially expressed during the process of WD, but the precise mechanisms responsible for these differentiations are not completely understood. In this study, we used microarrays to analyze the expression changes of the distal nerve stump at 0, 1, 4, 7, 14, 21 and 28 days after sciatic nerve injury in rats. The data revealed 6 076 differentially-expressed genes, with 23 types of expression, specifically enriched in genes associated with nerve development and axonogenesis, cytokine biosynthesis, cell differentiation, cytokine/chemokine production, neuron differentiation, cytokinesis, phosphorylation and axon regeneration. Kyoto Encyclopedia of Genes and Genomes pathway analysis gave findings related mainly to the MAPK signaling pathway, the Jak-STAT signaling pathway, the cell cycle, cytokine-cytokine receptor interaction, the p53 signaling pathway and the Wnt signaling pathway. Some key factors were NGF, MAG, CNTF, CTNNA2, p53, JAK2, PLCB1, STAT3, BDNF, PRKC, collagen II, FGF, THBS4, TNC and c-Src, which were further validated by real-time quantitative PCR, Western blot, and immunohistochemistry. Our findings contribute to a better understanding of the functional analysis of differentially-expressed genes in WD and may shed light on the molecular mechanisms of nerve degeneration and regeneration.Dengbing Yao Meiyuan Li Dingding Shen Fei Ding Shibi Lu Qing Zhao Xiaosong Gu 2013Neuroscience Bulletin2013,29,3:18
2Detection of serum IgM and IgG for COVID-19 diagnosis显示文摘Dear Editor,Infection with the novel coronavirus(SARS-CoV-2,which is the virus responsible for the coronavirus disease 2019(COVID-19))was first reported in Wuhan,China on December 31,2019.The outbreak of COVID-19 remains ongoing and was linked to more than 80,000 infected patients and more than 3,000 deaths in China as of March 7,2020(Holshue et al.,2020).Ling Zhong Junlan Chuan Bo Gong Ping Shuai Yu Zhou Yi Zhang Zhilin Jiang Dingding Zhang Xiaoqi Liu Shi Ma Yi Huang He Lin Qingwei Wang Lulin Huang Dan Jiang Fang Hao Juan Tang Chunqi Zheng Hua Yu Zhibin Wang Qi Jiang Tao Zeng Mei Luo Fanwei Zeng Fanxin Zeng Jianghai Liu Junxi Tian Yu Xu Tengxiang Long Kaiju Xu Xingxiang Yang Yuping Liu Yi Shi Li Jiang Zhenglin Yang 2020Science China(Life Sciences)2020,63,5:8
3Influences of Risk Perception and Sense of Place on Landslide Disaster Preparedness in Southwestern China显示文摘The effects of risk perception and sense of place on disaster preparedness have been widely reported.However, most studies have only demonstrated weak relationships and it is unknown whether these are applicable to China. This study investigated such relationships in hazard-threatened areas of the Three Gorges Reservoir area in southwestern China. Data were collected from 348 farming households in landslide-prone areas. Binary logistic and Tobit regression models were constructed to determine whether risk perception and sense of place influence landslide preparedness. The results show that:(1)Farming households' awareness of the need to prepare for disasters was relatively low, and disaster preparedness behaviors were mainly based on self-learning. Among the348 sampled households, 67% exhibited no disaster preparedness behavior, and only 2% adopted four of the five types of disaster preparedness behaviors. About a quarter of farming households consciously learned disaster-related knowledge.(2) Risk perception and sense of place had important influences on disaster preparedness. Respondentswho received higher scores on the perception of the probability of a landslide, the threat of a landslide, and the place dependence variables were more likely to adopt a greater number of disaster preparedness behaviors.Respondents with higher scores on the perception of controllability in the case of a landslide were less likely to adopt a greater number of disaster preparedness behaviors.Additionally, individual and household socioeconomic characteristics—education, loss, distance from hazard site,information acquisition channel, and housing material—were all related to household disaster preparedness behavior. This study contributes to the current literature by improving the understanding of the relationships of risk perception and sense of place to disaster preparedness in farming households threatened by geological disasters in southwestern China.Dingde Xu Li Peng Shaoquan Liu Xuxi Wang 2018International Journal of Disaster Risk Science2018,9,2:5
4Gene expression profiling of the rat sciatic nerve in early Wallerian degeneration after injury显示文摘Wallerian degeneration is an important area of research in modern neuroscience.A large number of genes are differentially regulated in the various stages of Wallerian degeneration,especially during the early response.In this study,we analyzed gene expression in early Wallerian degeneration of the distal nerve stump at 0,0.5,1,6,12 and 24 hours after rat sciatic nerve injury using gene chip microarrays.We screened for differentially-expressed genes and gene expression patterns.We examined the data for Gene Ontology,and explored the Kyoto Encyclopedia of Genes and Genomes Pathway.This allowed us to identify key regulatory factors and recurrent network motifs.We identified 1 546 differentially-expressed genes and 21 distinct patterns of gene expression in early Wallerian degeneration,and an enrichment of genes associated with the immune response,acute inflammation,apoptosis,cell adhesion,ion transport and the extracellular matrix.Kyoto Encyclopedia of Genes and Genomes pathway analysis revealed components involved in the Jak-STAT,ErbB,transforming growth factor-β,T cell receptor and calcium signaling pathways.Key factors included interleukin-6,interleukin-1,integrin,c-sarcoma,carcinoembryonic antigen-related cell adhesion molecules,chemokine(C-C motif) ligand,matrix metalloproteinase,BH3 interacting domain death agonist,baculoviral IAP repeat-containing 3 and Rac.The data were validated with real-time quantitative PCR.This study provides a global view of gene expression profiles in early Wallerian degeneration of the rat sciatic nerve.Our findings provide insight into the molecular mechanisms underlying early Wallerian degeneration,and the regulation of nerve degeneration and regeneration.Dengbing Yao Meiyuan Li Dingding Shen Fei Ding Shibi Lu Qin Zhao Xiaosong Gu 2012Neural Regeneration Research2012,7,17:5
5A microfluidic all-vanadium photoelectrochemical cell with a full-spectrum-responsive Ti2O3 photoanode for efficient solar energy storage显示文摘The all-vanadium photoelectrochemical cell is one of the promising solar energy storage technologies. However, conventional photoanodes surfer from low solar energy utilization efficiency as a result of narrow spectrum response and poor mass transfer.Hence, in this study, a microfluidic all-vanadium photoelectrochemical cell with a full-spectrum-responsive Ti2O3 photoanode was proposed for efficient solar energy storage. Experimental results indicated that the Ti2O3 photoanode responded to almost the full spectrum of sunlight and exhibited excellent photoresponse and operation stability, which facilitated efficient solar energy utilization. Additionally, the effects of the light intensity, vanadium ion concentration, and electrolyte flow rate were studied. It was found that increasing the light intensity and vanadium ion concentration and reducing the electrolyte flow rate promoted photoelectrochemical reactions and thus improved the solar energy storage performance. The obtained results demonstrate the feasibility and superiority of using Ti2O3 as the photoanode for a photoelectrochemical cell to achieve efficient solar energy storage.LIN YingYing FENG Hao CHEN Rong YE DingDing ZHANG Biao YU YouXu LI JinWang 2019Science China(Technological Sciences)2019,62,9:3
6Influences of Sense of Place on Farming Households' Relocation Willingness in Areas Threatened by Geological Disasters:Evidence from China显示文摘Scholars from environmental psychology,geography, disaster science, and sociology have recently focused attention on evacuation and relocation behaviors and influencing factors in hazard-threatened areas. However, existing studies are mainly focused on developed countries and the influence of individual characteristics,household characteristics, and the perception of risk of urban households on evacuation and relocation behaviors.Few studies examine developing countries and the influence of farmers' sense of place in geological hazardthreatened areas. Using statistics of farming households in an area threatened by landslides, this is a pilot study to explore the relationship of sense of place to the relocation willingness of farming households while controlling for other variables. The results show that:(1) Households with higher scores of place identity and place dependence are less willing to relocate, whereas place attachment has no significant relationship to household relocation willingness;(2) Risk perception dimensions, including probability,threat, and controllability have a significant relationship to household relocation willingness, while worry and fear of the unknown have no significant relationship;(3) Household characteristics, including income, whether a household has experienced economic loss from landslides, and social support are significantly correlated with household relocation willingness, while gender, age, experience, distance to hazard sites, size of household, children, older people, and housing material are not. The results for information and education are not robust. This study contributes to the current literature by improving the understanding of the relationship of sense of place to the relocation willingness of farming households in villages threatened by geological disasters in rural China.Dingde Xu Li Peng Shaoquan Liu Chunjiang Su Xuxi Wang Tiantian Chen 2017International Journal of Disaster Risk Science2017,8,1:2
7Biofilm formation and electricity generation of a microbial fuel cell started up under different external resistances显示文摘Liang Zhang Xun Zhu Jun Li Qiang Liao Dingding Ye 2011Journal of Power Sources2011,,15:2
8Prevalence and risk factors of enteral nutrition intolerance in intensive care unit patients: a retrospective study显示文摘Background: Feeding intolerance (FI) among intensive care unit (ICU) patients undergoing early continuous enteral nutrition (EN) is related to poor outcomes. This study aimed to explore the prevalence and risk factors of FI in ICU patients.Methods: We retrospectively enrolled 1057 patients who received early continuous EN via a nasogastric tube between January 2014 and August 2019. The prevalence of FI during the first 7 days of ICU stay was calculated, and the risk factors were investigated using multivariate logistic regression analysis.Results: The prevalence of FI during the first 7 days of ICU stay was 10.95%. FI occurred in 159 of 1057 (15.04%) patients on ICU day 2, 114 of 977 (11.67%) patients on ICU day 3, and 86 of 715 (12.03%) patients on ICU day 7. Mechanical ventilation (MV) (odds ratio [OR]: 1.928, 95% confidence interval [CI]: 1.064–3.493,P = 0.03) was an independent risk factor for FI defined by a gastric residual volume (GRV) of 200 mL and/or vomiting, and acute renal failure (OR: 3.445, 95% CI: 1.115–10.707,P = 0.032) was an independent risk factor of FI defined by a GRV of 500 mL and/or vomiting. Continuous renal replacement therapy (CRRT) was an independent predictor regardless of the FI defined by a GRV of 200 mL (OR: 2.064, 95% CI: 1.233–3.456,P = 0.006) or 500 mL (OR: 6.199, 95% CI: 2.108–18.228,P = 0.001) in the ICU patients.Conclusions: FI occurs frequently in early ICU days, especially in patients receiving MV and CRRT. However, further investigation of a consensus definition of FI and risk factors is still warranted in future studies.Kunrong Yu Na Guo Dingding Zhang Ying Xia Yanling Meng Li Weng Bin Du 2022Chinese Medical Journal2022,,15:2
9An MFC capable of regenerating the cathodic electron acceptor under sunlight显示文摘A renewable MFC (microbial fuel cell) cathode was used in this study because the iodide ion could react with oxygen to generate triiodide under natural sunlight.The feasibility of the regeneration of triiodide ion under natural sunlight and the effect of the regenerated triiodide ion concentration on the MFC performance were studied.The results showed that the power density of the MFC using triiodide ion as cathodic electron acceptor was significantly higher than that of using ferricyanate,and that the iodide ion can be oxidized to triiodide ion by oxygen in air at the expense of natural sunlight.In addition,it was obvious from the experimental results that the MFC performance was improved with the increase of the triiodide concentration,indicating that the concentration of triiodide ion had a critical effect on the MFC performance.The linear sweep voltammetry (LSV) curves for the electro-reduction of triiodide ion on the carbon paper were obtained and the results suggested that the diffusion process of triiodide ions to cathode was the control factor for the MFC performance.FU Qian,LI Jun,ZHU Xun,LIAO Qiang,YE DingDing & ZHANG Liang Institute of Engineering Thermophysics,Chongqing University,Chongqing 400030,China 2010Science China(Technological Sciences)2010,53,9:2
10An intelligent PE-malware detection system based on association mining 显示文摘YE Yanfang WANG Dingding LI Tao 2008Ioumal in Computer Virology2008,4,4:1
11Electrodeposition of Pd catalyst layer on graphite rod electrodes for direct formic acid oxidation显示文摘Biao Zhang Dingding Ye Jun Li Xun Zhu Qiang Liao 2012Journal of Power Sources2012,,:1
12Related-key security for hybrid encryption显示文摘Lu Xianhui Li Bao Jia Dingding 2014Lecture Notes in Computer Science2014,8783,:1
13SCENE : A Scalable Two-Stage PersonalizedNews Recommendation System显示文摘Lei Li Dingding Wang Tao Li 2011Research and development in Information Retrieval2011,32,1:1
14Feature Selection for Gene Expression Using Model-Based Entro- py显示文摘Zhu Shenghuo Wang Dingding Yu Kai Li Tao Gong Yihong 2010IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)2010,7,1:1
15ZMP-CoP Testing and Research of Biped Walking Robot 显示文摘Lin Dingding Liu Li Zhao Jiandong 2004Robot2004,6,4:1
16Insecticidal evaluation of Beauveria bassiana engineered to express a scorpion neurotoxin and a cuticle degrading protease 显示文摘Dingding Lu Monica Pava-Ripoll Zengzhi Li 2008Appl Microbiol Biotechnol2008,,81:1
17The partially linear regression model: Monte Carlo evidence from the projection pursuit regression approach 显示文摘Dingding Li Thanasis Stengos 2001Economics Letters2001,75,2:1
18ZMP-CoP Testing and Research of Biped Walking Robot显示文摘Lin Dingding Liu Li Zhao Jiandong 2004Robot2004,26,4:1
19Immune responses induced by DNA vaccines bearing Spike gene of PEDV combined with porcine IL-18显示文摘Siqingaowa Suo Yudong Ren Guangxing Li Dante Zarlenga Ri-e Bu Dingding Su Xunliang Li Pengchong Li Fandan Meng Chao Wang Xiaofeng Ren 2012Virus Research2012,,2:1
20Writeback throttling in a virtualized system with SCM显示文摘Dingding LI Xiaofei LIAO Hai JIN Yong TANG Gansen ZHAO 2016Frontiers of Computer Science2016,10,1:1
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