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| 1 | Cold adaptation in pigs depends on UCP3 in beige adipocytes显示文摘 | Jun Lin Chunwei Cao Cong Tao Rongcai Ye Meng Dong Qiantao Zheng Chao Wang Xiaoxiao Jiang Guosong Qin Changguo Yan Kui Li John R. Speakman Yanfang Wang Wanzhu Jin Jianguo Zhao | 2017 | Journal of Molecular Cell Biology2017,9,5: | 20 |
| 2 | Targeted delivery of chlorogenic acid by mannosylated liposomes to effectively promote the polarization of TAMs for the treatment of glioblastoma显示文摘Tumor-associated macrophages(TAMs)generally display an immunosuppressive M2 phenotype and promote tumor progression and metastasis,suggesting their potential value as a target in cancer immunotherapy.Chlorogenic acid(CHA)has been identified as a potent immunomodulator that promotes the polarization of TAMs from an M2 to an M1 phenotype.However,rapid clearance in vivo and low tumor accumulation have compromised the immunotherapeutic efficacy of CHA in clinical trials.In this study,mannosylated liposomes are developed for targeted delivery of CHA to TAMs.The immunoregulatory effects of CHA,along with the overall antitumor efficacy of CHA-encapsulated mannosylated liposomes,are investigated through in vitro and in vivo experiments.The prepared CHA-encapsulated mannosylated liposomes exhibit an ideal particle size,favorable stability,and preferential accumulation in tumors via the mannose receptor-mediated TAMs-targeting effects.Further,CHA-encapsulated mannosylated liposomes inhibit G422 glioma tumor growth by efficiently promoting the polarization of the pro-tumorigenic M2 phenotype to the anti-tumorigenic M1 phenotype.Overall,these findings indicate that CHA-encapsulated mannosylated liposomes have great potential to enhance the immunotherapeutic efficacy of CHA by inducing a shift from the M2 to the M1 phenotype. | Jun Ye Yanfang Yang Jing Jin Ming Ji Yue Gao Yu Feng Hongliang Wang Xiaoguang Chen Yuling Liu | 2020 | Bioactive Materials2020,5,3: | 9 |
| 3 | Famitinib in combination with concurrent chemoradiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma: a phase 1, open-label, dose-escalation Study显示文摘Background:Famitinib is a tyrosine kinase inhibitor against multiple targets,including vascular endothelial growth factor receptor 2/3,platelet-derived growth factor receptor,and stem cell factor receptor(c-kit).Previous studies have demonstrated anti-tumour activities of famitinib against a wide variety of advanced-stage solid cancers.We aimed to determine the safety and efficacy of famitinib with concurrent chemoradiotherapy(CCRT)in patients with locoregionally advanced nasopharyngeal carcinoma(NPC).We also evaluated the feasibility of contrast-enhanced ultrasound(D-CEUS)as a predictor of early tumour response to famitinib and to correlate functional parameters with clinical efficacy.Methods:The trial was conducted in subjects with stage III or IVa-b NPC using a 3+3 design of escalating fami-tinib doses.Briefly,subjects received 2 weeks of famitinib monotherapy followed by 7 weeks of famitinib plus CCRT.D-CEUS of the neck lymph nodes was performed at day 0,8 and 15 after famitinib was administered before starting concurrent chemoradiotherapy.End points included safety,tolerability and anti-tumour activity.Results:Twenty patients were enrolled(six each for 12.5,16.5 and 20 mg and two for 25 mg).Two patients in the 25 mg cohort developed dose-limiting toxicities,including grade 4 thrombocytopenia and grade 3 hypertension.The most common grade 3/4 adverse events were leukopenia,neutropenia and radiation mucositis.D-CEUS tests showed that more than 60%of patients achieved a perfusion parameter response after 2 weeks taking famitinib alone,and the parameter response was associated with disease improvement.In the famitinib monotherapy stage,three patients(15%)showed partial responses.The complete response rate was 65%at the completion of treatment and 95%3 months after the treatment ended.After a median follow-up of 44 months,the 3-year progression-free survival(PFS)and distant metastasis-free survival were 70%and 75%,respectively.Subjects with a decrease of perfusion parameter response,such as peak intensity decreased at least 30%after 1 week of famitinib treatment,had higher 3-year PFS(90.9%vs.44.4%,95%CI 73.7%-100%vs.11.9%-76.9%,P<0.001)than those with an increase or a reduction of less than 30%.Conclusions:The recommended famitinib dose for phase II trial is 20 mg with CCRT for patients with local advanced NPC.D-CEUS is a reliable and early measure of efficacy for famitinib therapies.Further investigation is required to confirm the effects of famitinib plus chemoradiotherapy. | Qiuyan Chen Linquan Tang Na Liu Feng Han Ling Guo Shanshan Guo Jianwei Wang Huai Liu Yanfang Ye Lu Zhang Liting Liu Pan Wang Yingqin Li Qingmei He Xiaoqun Yang Qingnan Tang Yang Li YuJing Liang XueSong Sun Chuanmiao Xie Yunxian Mo Ying Guo Rui Sun Haoyuan Mo Kajia Cao Xiang Guo Musheng Zeng Haiqiang Mai Jun Ma | 2018 | Cancer Communications2018,38,1: | 6 |
| 4 | Feasibility of Tea Saponin-Enhanced Soil Washing in a Soybean Oil-Water Solvent System to Extract PAHs/Cd/Ni Efficiently from a Coking Plant Site显示文摘Mixed contaminated brownfield sites have brought serious risks to human health and environmental safety. With the purpose of removing polycyclic aromatic hydrocarbons(PAHs) and heavy metals from a coking plant site, an innovative technology for ex-situ washing was developed in the present work. The combination of 15.0 mL L^(-1) soybean oil and 7.5 g L^(-1) tea saponin proved an effective method to extract co-pollutants from soil. After two consecutive washing cycles, the efficiency rates of removal for 3-, 4-,5(+6)-ring, and total PAHs, Cd, and Ni were approximately 98.2%, 96.4%, 92.3%, 96.3%, 94.1%, and 89.4%, respectively. Meanwhile,as evaluated by Tenax extraction method and metal stability indices, the residual PAHs and heavy metals after consecutive washing mainly existed in the form with extremely low bioaccessibility in the soil. Thus, in the soil after two washing cycles, there appeared limited environmental transfer risk of co-pollutants. Moreover, a subsequent precipitation method with alkaline solution and PAHdegrading strain Sphingobium sp. PHE9 inoculation effectively removed 84.6%–100% of Cd, 82.5%–91.7% of Ni, and 92.6%–98.4% of PAHs from the first and second washing solvents. The recovered solvents also exhibited a high recycling effectiveness. Therefore, the combined cleanup strategy proposed in this study proved environmentally friendly, which also played a major role in risk assessment and management in mixed polluted sites. | YE Mao SUN Mingming XIE Shanni LIU Kuan FENG Yanfang ZHAO Yu WAN Jinzhong HU Feng LI Huixin ZONG Lianggang JIANG Xin | 2017 | Pedosphere2017,27,3: | 5 |
| 5 | Thermoresponsive Lignin-Reinforced Poly(Ionic Liquid)Hydrogel Wireless Strain Sensor显示文摘To meet critical requirements on flexible electronic devices,multifunctionalized flexible sensors with excellent electromechanical performance and temperature perception are required.Herein,lignin-reinforced thermoresponsive poly(ionic liquid)hydrogel is prepared through an ultrasound-assisted synthesized method.Benefitting from the electrostatic interaction between lignin and ionic liquid,the hydrogel displays high stretchability(over 1425%),excellent toughness(over 132 kPa),and impressive stress loading-unloading cyclic stability.The hydrogel strain sensor presents excellent electromechanical performance with a high gauge factor(1.37)and rapid response rate(198 ms),which lays the foundation for human body movement detection and smart input.Moreover,owing to the thermal-sensitive feature of poly(ionic liquid),the as-prepared hydrogel displays remarkable thermal response sensitivity(0.217℃^(-1))in body temperature range and low limit of detection,which can be applied as a body shell temperature indicator.Particularly,the hydrogel can detect dual stimuli of strain and temperature and identify each signal individually,showing the specific application in human-machine interaction and artificial intelligence.By integrating the hydrogel strain sensor into a wireless sensation system,remote motion capture and gesture identification is realized in real-time. | Xinyu Qu Ye Zhao Zi’ang Chen Siying Wang Yanfang Ren Qian Wang Jinjun Shao Wenjun Wang Xiaochen Dong | 2021 | Research2021,,1: | 3 |
| 6 | Structural Characterization of Glucan Produced by Lactobacillus sake L-7 from Sausage显示文摘A linear glucan was produced by Lactobacillus sake L-7 isolated from homemade sausage. Cultivation of the strain in Man–Rogosa–Sharpe(MRS) medium containing 50 g/L sucrose yielded 5.3 g/L of purified exopolysaccharide(EPS). The EPS was characterized by gas chromatography(GC), Fourier-transform infrared(FT-IR) spectroscopy, high-performance sizeexclusion chromatography(HPSEC), nuclear magnetic resonance(NMR) spectroscopy, and scanning electron microscopy(SEM). The monosaccharide composition of the EPS was glucose, and its molecular weight was 1 × 10~7 Da. The FT-IR and NMR spectra revealed that the L-7 EPS was a linear glucan with α-(1 → 6) glucosidic bonds. SEM images of the dried EPS revealed a hollow tubular structure. The water solubility index and water holding capacity of L-7 EPS were 96 and 272%, respectively. The results of hydrolysis indicated that L-7 EPS was not susceptible to hydrolysis by physiological barriers and can be used as a soluble dietary fiber with health benefits. All these characteristics suggest that L-7 EPS might have potential applications in the food, cosmetic, and pharmaceutical industries. | Fang Feng Qingqing Zhou Yanfang Yang Fangkun Zhao Renpeng Du Ye Han Zhijiang Zhou | 2019 | Transactions of Tianjin University2019,25,1: | 3 |
| 7 | Ultradurable,freeze-resistant,and healable MXene-based ionic gels for multi-functional electronic skin显示文摘Hydrogel is a potential matrix material of electronic-skins(E-skins)because of its excellent ductility,tunability,and biocompatibility.However,hydrogel-based E-Skins will inevitably lose their sensing performance in practical applications for water loss,physical damage,and ambient interferences.It remains a challenge to manufacture highly durable gel-based E-skins.Herein,an E-Skin is fabricated by introducing ionic liquids(ILs)into MXene-composited binary polymer network.The obtained ionic gel shows excellent mechanical properties,strong adhesion,and superior tolerance to harsh environments.The E-skin exhibits high sensitivity to both strain and pressure in a wide range of deformations,which enables a monitoring function for various human motions and physiological activities.Importantly,the E-skin shows consistent electrical response after being stored in the open air for 30 days and can be quickly healed by irradiation with 808 nm near-infrared light,originating from the photo-thermal effect induced self-healing acceleration.It is noteworthy that the E-skin also reveals a highly sensitive perception of temperature and near-infrared light,displaying the promising potential applications in the multifunctional flexible sensor. | Yao Lu Xinyu Qu Siying Wang Ye Zhao Yanfang Ren Wenli Zhao Qian Wang Chencheng Sun Wenjun Wang Xiaochen Dong | 2022 | Nano Research2022,15,5: | 2 |
| 8 | Isolation, Purification, and Characterization of Exopolysaccharide Produced by Leuconostoc Citreum N21 from Dried Milk Cake显示文摘A strain with high production of exopolysaccharide(EPS) was isolated from dried milk cake(a traditional fermented food from Inner Mongolia). The strain was called N21 and later identified as Leuconostoc citreum( Leu. citreum). The strain was cultured in Man-Rogosa-Sharpe medium containing 50 g/L of sucrose for 48 h at 30 °C and the EPS purified, with a yield of 24.5 g/L. An average molecular weight of 6.07 × 10~6 g/mol was determined by high-performance size-exclusion chromatography. The structure of the purified EPS was investigated through gas chromatography, ~1H and ^(13)C nuclear magnetic resonance spectroscopy, and Fourier transform infrared spectroscopy. The results demonstrated a polysaccharide composed of D-glucopyranose units in a linear chain with consecutive α(1 → 6) linkages. No branching was found in the structure of the exopolysaccharide. The purified EPS showed high water solubility and emulsibility. Based on the thermogravimetric curve, the degradation temperature of the EPS was 308.47 °C, which suggested that the dextran in the study exhibited high thermal stability. The results indicated that Leu. citreum N21 could be widely used to produce linear EPS and that the EPS has potential applications in food science and processing as a food additive. | Yanfang Yang Fang Feng Qingqing Zhou Fangkun Zhao Renpeng Du Zhijiang Zhou Ye Han | 2019 | Transactions of Tianjin University2019,25,2: | 2 |
| 9 | Construction of chlorogenic acid-containing liposomes with prolonged antitumor immunity based on T cell regulation显示文摘As a potential cancer immunotherapeutic agent,chlorogenic acid(CHA)has entered phase II clinical trials in China as a lyophilized powder formulation for treating glioma.However,the in vivo instability of CHA necessitates daily intramuscular injections,resulting in patient noncompliance.In this study,CHA-phospholipid complex(PC)-containing PEGylated liposomes(CHA-PC PEG-Lipo,named as CPPL),with CHA-PC as the drug intermediate,were prepared to lower the administration frequency.CPPL demonstrated excellent physicochemical properties,enhanced tumor accumulation,and inhibited tumor growth even when the administration interval was prolonged to 4 days when compared to a CHA solution and CHA-PC loaded liposomes(CHA-PC Lipo,labeled as CPL),both of which only demonstrated antitumor efficacy with once-daily administration.Further evaluation of the in vivo antitumor immune mechanism suggested that the extended antitumor immune efficacy of CPPL could be attributed to its distinct immune-stimulating mechanism when compared with CHA solution and CPL,such as stimulating both CD4+and CD8+T cell infiltration,inhibiting myeloid-derived suppressor cell expression,reducing the expression of Th2 related factors,and notably,increasing the memory T cells in tumor tissues.This CHA-containing formulation could reduce the frequency of in vivo CHA administration during cancer treatment via T cells,especially memory T cell regulation. | Yun Zhang Yanfang Yang Jun Ye Yue Gao Hengfeng Liao Junzhuo Zhou Yu Feng Dongdong Liu Yingying Meng Xiaoguang Chen Lili Gao Yuling Liu | 2021 | Science China(Life Sciences)2021,64,7: | 2 |
| 10 | CIMDS: A- dapting Postprocessing Techniques of Associative Classifi- cation for Malware Detection 显示文摘 | YE Yanfang LI Tao JIANG Qingshan | 2010 | IEEE Transactions On Systems Man And Cybernetics-Part C : Applications And Reviews2010,40,3: | 1 |
| 11 | An intelligent PE-malware detection system based on association mining 显示文摘 | YE Yanfang WANG Dingding LI Tao | 2008 | Ioumal in Computer Virology2008,4,4: | 1 |
| 12 | CIMDS: a- dapting post-processing techniques of associative classifica- tion for virus detection 显示文摘 | YE Yanfang LI Tao JIANG Qingshan | 2010 | IEEE Transactions on Sys- tems Man and Cybernetics Part C: Applications and Reviews2010,40,3: | 1 |
| 13 | Ensemble clustering for internet security applications 显示文摘 | ZHUANG Weiwei YE Yanfang CHEN Yong | 2012 | Systems Man and Cybernetics Part C: Applications and Reviews IEEE Transactions on2012,42,6: | 1 |
| 14 | A novel immunogenomic signature to predict prognosis and reveal immune infiltration characteristics in pancreatic ductal adenocarcinoma显示文摘Background:The immune response in the tumor microenvironment(TME)plays a crucial role in cancer progression and recurrence.We aimed to develop an immune-related gene(IRG)signature to improve prognostic predictive power and reveal the immune infiltration characteristics of pancreatic ductal adenocarcinoma(PDAC).Methods:The Cancer Genome Atlas(TCGA)PDAC was used to construct a prognostic model as a training cohort.The International Cancer Genome Consortium(ICGC)and the Gene Expression Omnibus(GEO)databases were set as validation datasets.Prognostic genes were screened by using univariate Cox regression.Then,a novel optimal prognostic model was developed by using least absolute shrinkage and selection operator(LASSO)Cox regression.Cell type identification by estimating the relative subsets of RNA transcripts(CIBERSORT)and estimation of stromal and immune cells in malignant tumors using expression data(ESTIMATE)algorithms were used to characterize tumor immune infiltrating patterns.The tumor immune dysfunction and exclusion(TIDE)algorithm was used to predict immunotherapy responsiveness.Results:A prognostic signature based on five IRGs(MET,ERAP2,IL20RB,EREG,and SHC2)was constructed in TCGA-PDAC and comprehensively validated in ICGC and GEO cohorts.Multivariate Cox regression analysis demonstrated that this signature had an independent prognostic value.The area under the curve(AUC)values of the receiver operating characteristic(ROC)curve at 1,3,and 5 years of survival were 0.724,0.702,and 0.776,respectively.We further demonstrated that our signature has better prognostic performance than recently published ones and is superior to traditional clinical factors such as grade and tumor node metastasis classification(TNM)stage in predicting survival.Moreover,we found higher abundance of CD8+T cells and lower M2-like macrophages in the low-risk group of TCGA-PDAC,and predicted a higher proportion of immunotherapeutic responders in the low-risk group.Conclusions:We constructed an optimal prognostic model which had independent prognostic value and was comprehensively validated in external PDAC databases.Additionally,this five-genes signature could predict immune infiltration characteristics.Moreover,the signature helped stratify PDAC patients who might be more responsive to immunotherapy. | Ang Li Bicheng Ye Fangnan Lin Yilin Wang Xiaye Miao Yanfang Jiang | 2022 | Precision Clinical Medicine2022,5,2: | 1 |
| 15 | An intelligent PE-malware detection system based on association mining显示文摘 | YE YANFANG WANG DINGDINC LI TAO | 2008 | Journal in Computer Virology2008,4,4: | 1 |
| 16 | Synthesis and Antitumor Activity of Sorafenib Analogs Containing a Tetrazole Moiety显示文摘A novel series of diaryl biuret derivatives containing a tetrazole moiety was designed and synthesized.All the target compounds were evaluated for their in vitro antitumor activity against HT-29,HepG2,MCF-7 and A549 cells by MTT assay.Most of them exhibited obvious antitumor activity,and four of them(4a,4c,4h and 7a)were superior to sorafenib in general.Among them,Compound 4h displayed more potent activity than sorafenib in all tested cancer cells.Compound 4c exhibited the most outstanding activity in inhibition of growth of HepG2 cells(IC50=0.55 μmol/L).Further,they both revealed favorable metabolic stability in in vitro assay.Compounds 4c and 4h are promising candidates for further development. | TIAN Ye YU Simiao CAI Lude GONG Guowei WU Guodong QI Hongxia ZHAO Yanfang QIN Mingze | 2019 | Chemical Research in Chinese Universities2019,35,1: | 0 |
| 17 | Tumor-targeting intravenous lipid emulsion of paclitaxel:Characteristics,stability,toxicity,and toxicokinetics显示文摘Lipid nanoemulsions are promising nanodrug delivery carriers that can improve the efficacy and safety of paclitaxel(PTX).However,no intravenous lipid emulsion of PTX has been approved for clinical treatment,and systemic safety profiles have not yet been reported.Here we outline the development of a PTXloaded tumor-targeting intravenous lipid emulsion(PTX Emul)and describe its characteristics,colloidal stability,and systemic safety profiles in terms of acute toxicity,long-term toxicity,and toxicokinetics.We also compare PTX Emul with conventional PTX injection.Results showed that PTX Emul exhibited an ideal average particle size(approximately 160 nm)with narrow size distribution and robust colloidal stability under different conditions.Hypersensitivity reaction and hemolysis tests revealed that PTX Emul did not induce hypersensitivity reactions and had no hemolytic potential.In addition,where the alleviated systemic toxicity of PTX Emul may be attributed to the altered toxicokinetic characteristics in beagle dogs,including the decreased AUC and increased plasma clearance and volume of distribution,PTX Emul alleviated acute and long-term toxicity as evidenced by the enhanced the median lethal dose and approximate lethal dose,moderate body weight change,decreased bone marrow suppression and organ toxicity compared with those under PTX injection at the same dose.A fundamental understanding of the systemic safety profiles,high tumor-targeting efficiency,and superior antitumor activity in vivo of PTX Emul can provide powerful evidence of its therapeutic potential as a future treatment for breast cancer. | Jun Ye Lin Li Jiye Yin Hongliang Wang Renjie Li Yanfang Yang Yongbiao Guan Xuejun Xia Yuling Liu | 2022 | Journal of Pharmaceutical Analysis2022,12,6: | 0 |
| 18 | Strategies and opportunities of micro/nano delivery systems for targeted therapy of ulcerative colitis:Focus on underlying mechanisms and future perspectives显示文摘Ulcerative colitis(UC)is a common progressive inflammatory disease whose incidence has increased rapidly in recent years,and can develop into colorectal cancer in severe cases.There are currently no adequate or effective treatments for UC due to the fact that some patients have found suboptimal results after repeated administration,while others have experienced adverse effects.With the rapid development of nanotechnology,developing innovative colon-targeting platforms is essential to improving efficacy,reducing side effects,and improving patient compliance.In this review,we summarize the pathophysiological characteristics of UC and the most recent status of numerous nanodrug delivery systems based on different targeting mechanisms in treating UC.Oral,intravenous,and rectal drug delivery nanoparticles targeting the colon are discussed,which can provide ideas for the design of colon-targeting nanoparticles for the treatment of colon diseases,especially for the treatment of UC.Last but not least,we provide a glimpse into the future of colon-targeted delivery systems,as well as future advancements in the field. | Zihan Liu Han Liu Jialing Cheng Hongliang Wang Yanfang Yang Jun Ye Yuling Liu | 2024 | Chinese Chemical Letters2024,35,2: | 0 |
| 19 | Unlocking the potential of amorphous calcium carbonate: A star ascending in the realm of biomedical application显示文摘Calcium-based biomaterials have been intensively studied in the field of drug delivery owing to their excellent biocompatibility and biodegradability.Calcium-based materials can also deliver contrast agents,which can enhance real-time imaging and exert a Ca^(2+)-interfering therapeutic effect.Based on these characteristics,amorphous calcium carbonate(ACC),as a brunch of calcium-based biomaterials,has the potential to become a widely used biomaterial.Highly functional ACC can be either discovered in natural organisms or obtained by chemical synthesis However,the standalone presence of ACC is unstable in vivo.Additives are required to be used as stabilizers or core-shell structures formed by permeable layers or lipids with modified molecules constructed to maintain the stability of ACC until the ACC carrier reaches its destination.ACC has high chemical instability and can produce biocompatible products when exposed to an acidic condition in vivo,such as Ca^(2+) with an immune-regulating ability and CO_(2) with an imaging-enhancing ability.Owing to these characteristics,ACC has been studied for selfsacrificing templates of carrier construction,targeted delivery of oncology drugs,immunomodulation,tumor imaging,tissue engineering,and calcium supplementation.Emphasis in this paper has been placed on the origin,structural features,and multiple applications of ACC.Meanwhile,ACC faces many challenges in clinical translation,and long-term basic research is required to overcome these challenges.We hope that this study will contribute to future innovative research on ACC. | Han Liu Zhiyang Wen Zihan Liu Yanfang Yang Hongliang Wang Xuejun Xia Jun Ye Yuling Liu | 2024 | Acta Pharmaceutica Sinica B2024,14,2: | 0 |
| 20 | Thermoresponsive Lignin-Reinforced Poly(Ionic Liquid) Hydrogel Wireless Strain Sensor显示文摘To meet critical requirements on flexible electronic devices,multifunctionalized flexible sensors with excellent electromechanical performance and temperature perception are required.Herein,lignin-reinforced thermoresponsive poly(ionic liquid)hydrogel is prepared through an ultrasound-assisted synthesized method.Benefitting from the electrostatic interaction between lignin and ionic liquid,the hydrogel displays high stretchability(over 1425%),excellent toughness(over 132 kPa),and impressive stress loading-unloading cyclic stability.The hydrogel strain sensor presents excellent electromechanical performance with a high gauge factor(1.37)and rapid response rate(198 ms),which lays the foundation for human body movement detection and smart input.Moreover,owing to the thermal-sensitive feature of poly(ionic liquid),the as-prepared hydrogel displays remarkable thermal response sensitivity(0.217℃^(-1))in body temperature range and low limit of detection,which can be applied as a body shell temperature indicator.Particularly,the hydrogel can detect dual stimuli of strain and temperature and identify each signal individually,showing the specific application in human-machine interaction and artificial intelligence.By integrating the hydrogel strain sensor into a wireless sensation system,remote motion capture and gesture identification is realized in real-time. | Xinyu Qu Ye Zhao Zi’ang Chen Siying Wang Yanfang Ren Qian Wang Jinjun Shao Wenjun Wang Xiaochen Dong | 2022 | Research2022,,1: | 0 |