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| 1 | Oxidative stress in humans following the Pringle manoeuvre显示文摘BACKGROUND: Oxidative stress is induced in the liver by application of the Pringle manoeuvre. Malondialdehyde is a carbonyl compound formed during lipid peroxidation and prostaglandin biosynthesis, which combines with DNA to form a number of adducts. Among them is the DNA ad-duct; 3-(2-deoxybeta-dierythropentafuranosyl) pyr [1,2-alpha]-purin-10(3H) one or M1G. This study was undertaken to determine the suitability of M1G as a novel marker of ischemia-reperfusion injury in the liver and its correlation with both the length of Pringle clamp application and the overall length of the operation. METHODS: Normal and colorectal liver metastatic tissues were obtained in 12 patients before and after application of the Pringle manoeuvre. All samples were snap-frozen in liquid nitrogen at -80 ℃. DNA was extracted and M1G quantification was performed by immunoslotblot analysis. RESULTS: M1G levels in normal liver tissue were 4.0 + 1.0 per 107 nucleotides before the Pringle manoeuvre and 7.4 ± 1.0 per 10 nucleotides after the Pringle manoeuvre (mean ± standard deviation) (P<0.05 by ANOVA). M1G levels in malignant liver tissue were 2.5 ±1.4 per 107 nucleotides before the Pringle manoeuvre and 6. 5 ±1.9 adducts per 10 nucleotides after the Pringle manoeuvre (P <0. 05). Ad-duct levels in normal liver tissue showed a significant correlation with cumulative period of Pringle application. CONCLUSIONS: This is the first time that the tissue levels of M1G before and after application of the Pringle manoeuvre have been studied. The results show that the Pringle manoeuvre exerts significant oxidative stress in human hepa-tocytes, which is Pringle-time dependent. The results highlight the potential for oxidative DNA adducts levels as a tool for measuring the severity of ischemia-reperfusion injury. | Giuseppe Garcea Andreas Gescher William Steward Ashley Dennison David Berry | 2006 | Hepatobiliary & Pancreatic Diseases International2006，5，2： | 4 |
| 2 | 从博物馆到博物馆群——古根海姆博物馆的历程显示文摘总部设在纽约的美国古根海姆博物馆,在西班牙毕尔巴鄂、意大利威尼斯、德国柏林和美国拉斯维加斯拥有4处分馆。2006年7月又与阿布扎比政府签订合同在当地建立分馆,这将会是古根海姆众多美术馆中最大的一个。与此同时,古根海姆也一直积极谋求在亚洲地区、尤其是中国的战略发展。这种连锁经营的模式和全球化策略已经成为世界博物馆领域一个不容忽视的趋势'。美国艺术300年:适应与革新'大型展览的构想始于1998年,其后有着十年的筹展历程。2006年10月16日,美国古根海姆博物馆代表团访问中国美术馆,亚洲战略发展部主任Min Jun Kim,展览收藏及设计部主任Karen Meyerhoff,展览策展人Susan Davidson,教育部主任Kim Kanitani等就展览事宜,与中国美术馆馆长范迪安,副馆长钱林祥、马书林及相关部门的负责人举行了会谈,并分三个小组,就展览、教育、学术活动等合作的具体问题进行讨论。此次会谈之后,展览进行到实质性的筹备阶段,各项工作全面展开。11月,古根海姆博物馆向中国美术馆馆长范迪安、学术一部主任陈履生发出访问古根海姆博物馆的邀请,后因范迪安馆长不能成行,而由学术一部主任陈履生作为代表于12月5日赴纽约,与先期在纽约的公共教育部副主任何琳,在古根汉美术馆与泰拉基金会公共教育部主任Jennifer、古根汉美术馆策展人Susan、教育部主任Kim、教育部资深经理Christina、发展部主任Renee、亚洲部主管Alexandra,就'美国艺术三百年'展览的一些具体事宜和两馆合作的其他问题进行了会谈。2007年1月4日至5日,古根海姆博物馆财团发展部主任Meryl Cohen一行再次访问中国美术馆,中方谈判小组与美方代表就展览新闻发布会、开幕式、晚宴等相关问题进行协商确认,并达成共识。可以说,两馆对于这个展览的筹备都给与了高度的重视,组织精心而细致,计划周密而严谨。为了更好地向读者全面介绍这个展览,以及为这个展览作出重要贡献的古根海姆博物馆,本刊特别选译了由古根海姆新任馆长Lisa Dennison(当时任副馆长)(1)撰写的这篇文章,介绍古根海姆博物馆由一个家族的私人收藏到如今庞大博物馆群的发展过程及其背后的经营理念。 | Lisa Dennison 赵容 | 2007 | 中国美术馆2007，0，2： | 3 |
| 3 | 中国模内标签发展现状与分析显示文摘模内标签是目前标签应用的最高形式,与当前流行的不干胶标签相比,模内标签近乎完美,所以近年来发达国家的模内标签产业,包括标签原材料、印刷加工工艺、制造模具和塑料成型设备,如吹塑机.注塑机等均得到了快速发展。 | Avery Dennison 傅强 | 2007 | 印刷技术2007，，12： | 2 |
| 4 | A comparison of error metrics and constraints for multiple endmember spectral mixture analysis and spectral angle mapper显示文摘 | Philip E. Dennison Kerry Q. Halligan Dar A. Roberts | 2004 | Remote Sensing of Environment2004，，3： | 2 |
| 5 | The diagnosis and management of Sphincter of Oddi dysfunction: a systematic review显示文摘 | Thomas Hall Ashley Dennison Giuseppe Garcea | 2012 | Langenbeck’s Archives of Surgery2012，，6： | 2 |
| 6 | Elevation of Carbohydrate Antigen 19.9 in Benign Hepatobiliary Conditions and Its Correlation with Serum Bilirubin Concentration显示文摘 | S. L. Ong A. Sachdeva G. Garcea G. Gravante M. S. Metcalfe D. M. Lloyd D. P. Berry A. R. Dennison | 2008 | Digestive Diseases and Sciences2008，，12： | 2 |
| 7 | Physiologically based pharmacokinetic/pharmacodynamic model for the organophosphorus pesticide dizainon 显示文摘 | Poet TS Kousba AA Dennison SL | 2004 | Neurotoxicology2004，25，： | 1 |
| 8 | Median nerve injuries associated with distal radius fractures显示文摘 | David G Dennison MD | 2006 | Tech Orthop2006，21，1： | 1 |
| 9 | Sediment ammonium availability and eelgrass (Zostera marina ) growth显示文摘 | Dennison W C Aller R C Alberte R S | 1987 | Marine Biology1987，94，3： | 1 |
| 10 | The effects of vegetation phenology on endmember selection and species mapping in southern California Chaparral显示文摘 | PHILIP E Dennison DAR A Roberts | 2003 | Remote Sensing of Environment2003，87，： | 1 |
| 11 | Anthropology and tourism 显示文摘 | Dennison Nash Valene L Smith | 1991 | Annals of Tourism Research1991，18，1： | 1 |
| 12 | A comparison of error metrics and constraints for multiple endmember spectral mixture analysis and spectral angle mapper显示文摘 | Dennison P E Halligan K Q Roberts D A | 2004 | Remote Sensing of Environment2004，93，3： | 1 |
| 13 | Geographic variation in osteopo- rotic hip fracture incidence: the growing importance of Asian influences in coming decades 显示文摘 | Dhanwal DK Cooper C Dennison EM | 2010 | J Osteoporos2010，8，2： | 1 |
| 14 | Epigenetic influences in the developmental origins of osteoporosis显示文摘 | Holroyd C Harvey N Dennison E | | 0，，02： | 1 |
| 15 | Eutrophication and harmful algal blooms: A scientific consensus显示文摘 | J. Heisler P.M. Glibert J.M. Burkholder D.M. Anderson W. Cochlan W.C. Dennison Q. Dortch C.J. Gobler C.A. Heil E. Humphries A. Lewitus R. Magnien H.G. Marshall K. Sellner D.A. Stockwell D.K. Stoecker M. Suddleson | 2008 | Harmful Algae2008，，1： | 1 |
| 16 | Influence of nitrogen source and availability on amino acids pigments and tissue nitrogen of Gracilaria eduils (Rhodophyta) 显示文摘 | Dennison W C Stewart G R | 1996 | J Phycol1996，32，： | 1 |
| 17 | A review of psychological correlates of adjustment in patients with multiple sclerosis显示文摘 | Dennison L Moss-Morris R Chalder T | 2009 | Clin Psychol Rev2009，29，： | 1 |
| 18 | Quantification of oxygen-induced retinopathy in the mouse:a model of vessel loss,vessel regrowth and pathological angiogenesis显示文摘 | Connor KM Krah NM Dennison RJ | 2009 | Nat Protoc2009，4，11： | 1 |
| 19 | Inflammation, Telomere Length, and Grip Strength: A 10-year Longitudinal Study显示文摘 | Daniel Baylis Georgia Ntani Mark H. Edwards Holly E. Syddall David B. Bartlett Elaine M. Dennison Carmen Martin-Ruiz Thomas Zglinicki Diana Kuh Janet M. Lord Avan Aihie Sayer Cyrus Cooper | 2014 | Calcified Tissue International2014，，1： | 1 |
| 20 | In situ seagrass photosynthesis measured using a submersible,pulse-am- plitude modulated fluorometer显示文摘 | Ralph P J Gademann R Dennison W C | 1998 | Marine Biology1998，132，3： | 1 |
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