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| 1 | Clinical diagnosis of Alzheimer?s disease: Report of the NINCDS-ADRDA Work Group* under the auspices of Department of Health and Human Services Task Force on Alzheimer?s Disease显示文摘 | Guy McKhann David Drachman Marshall Folstein Robert Katzman Donald Price Emanuel M. Stadlan | 1984 | Neurology1984，，7： | 7 |
| 2 | Brain metastasis in advanced colorectal cancer: results from the South Australian metastatic colorectal cancer (SAmCRC) registry显示文摘Objective:Brain metastasis is considered rare in metastatic colorectal cancer(mCRC);thus,surveillance imaging does not routinely include the brain.The reported incidence of brain metastases ranges from 0.6% to 3.2%.Methods:The South Australian mCRC Registry(SAmCRC)was analyzed to assess the number of patients presenting with brain metastasis during their lifetime.Due to small numbers,a descriptive analysis is presented.Results:Only 59 patients of 4,100 on the registry at the time of analysis had developed brain metastasis(1.4%).The clinical characteristics of those with brain metastasis were as follows:the median age was 65.3 years and 51% were female.Where the V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog(KRAS)mutation status of the tumor was known,the majority harbored a KRAS mutation(55%);31(53%)underwent craniotomy and 55(93%)underwent whole-brain radiotherapy.The median survival time from diagnosis of brain metastasis was 4.2 months(95% confidence interval 2.9–5.5).Patients who underwent craniotomy and radiotherapy had superior survival compared to those who underwent whole-brain radiotherapy(8.5 months vs.2.2 months,respectively).Data from the SAmCRC(a population-based registry)confirm that brain metastases are rare and the median time to development is approximately 2 years.Conclusions:Brain metastasis is a rare outcome in advanced CRC.Patients within the registry tended to be female,young in age,and harbored with higher rates of KRAS mutations.Whether routine surveillance brain scanning should be considered remains controversial given the relative rarity of developing brain metastases in mCRC and ultimately,most patients with central nervous system involvement die from their extracranial disease. | Gonzalo Tapia Rico Timothy J. Price Christos Karapetis Cynthia Piantadosi Rob Padbury Amitesh Roy Guy Maddern James Moore Scott Carruthers David Roder Amanda R. Townsend | 2017 | Cancer Biology & Medicine2017，14，4： | 3 |
| 3 | 重塑能源-中国:能效在中国面向2050年路线图中的作用显示文摘作为《巴黎协定》承诺的一部分,中国计划在2030年左右达到二氧化碳(CO_2)排放峰值并争取尽早达峰。在研究如何实现上述减排承诺的前提下,中美研究人员组成的团队构建了一个自下而上的中国能源供需综合模型。基于该模型对比分析了两种情景的差异,即沿着当前趋势发展的参考路径情景以及'重塑能源'替代路径情景。'重塑能源'替代路径是指为满足国家需求,在2050年前最大程度地应用当前成本有效的能源效率策略和可再生能源。结果表明,如果中国走更积极的重塑能源路径,那么其二氧化碳排放量可比参考路径提前11年达峰。本文重点分析了在更积极的路径下能源效率策略对于二氧化碳减排的作用。除能源效率外,本研究还分析了燃料替换(从碳密集型燃料转向其他燃料)的减排作用。结果表明,对于重塑能源情景,能源效率提高及相关策略贡献了中国2050年二氧化碳总减排潜力的75%,而燃料替换仅占25%。为在中国实现上述具有显著成本效益的能效潜力。 | Lynn Price Nina Khanna Nan Zhou David Fridley Ali Hasanbeigi Hongyou Lu Feng Wei 戴彦德 田智宇 杨宏伟 白泉 朱跃中 熊华文 张建国 Jon Creyts Kate Chrisman Ellen Franconi Josh Agenbroad Michael Bendewald Yi Ke Robert McIntosh David Mullaney Clay Stranger Daniel Wetzel Cvrd Yee | 2018 | 科学与管理2018，38，3： | 3 |
| 4 | Immunodominance and functional alterations of tumor‐associated antigen‐specific CD8+ T‐cell responses in hepatocellular carcinoma显示文摘 | Tobias Flecken Nathalie Schmidt Sandra Hild Emma Gostick Oliver Drognitz Robert Zeiser Peter Schemmer Helge Bruns Thomas Eiermann David A. Price Hubert E. Blum Christoph Neumann‐Haefelin Robert Thimme | 2014 | Hepatology2014，，： | 2 |
| 5 | Carrying capacity reconsidered显示文摘 | David Price | 1999 | Population and Environment1999，，1： | 2 |
| 6 | Epidemiology of neuroendocrine cancers in an Australian population显示文摘 | Colin Luke Timothy Price Amanda Townsend Christos Karapetis Dusan Kotasek Nimit Singhal Elizabeth Tracey David Roder | 2010 | Cancer Causes & Control2010，，6： | 2 |
| 7 | Current evidence and future research needs for FeNO measurement in respiratory diseases显示文摘 | Leif Bjermer Kjell Alving Zuzana Diamant Helgo Magnussen Ian Pavord Giorgio Piacentini David Price Nicolas Roche Joaquin Sastre Mike Thomas Omar Usmani | 2014 | Respiratory Medicine2014，，： | 2 |
| 8 | 平滑肌肉瘤中PRUNE2mRNA的表达及其与非编码RNAPCA3的一致性关系显示文摘目的 探讨平滑肌肉瘤中PRUNE2mRNA的表达及其与非编码RNAPCA3的关系。方法采用安捷伦基凶表达芯片的方法检测31例平滑肌肉瘤和42例胃肠间质瘤中PRUNE2mRNA的表达水平,分析其表达与平滑肌肉瘤患者的预后关系;采用实时荧光定量聚合酶链反应的方法分析13例平滑肌肉瘤中PCA3mRNA和PRUNE2mRNA的表达水平并分析二者间的关系。7例前列腺癌组织作为PCA3mRNA表达的阳性对照。结果在31例平滑肌肉瘤中,PRUNE2mRNA的平均表达水平为368.43±29.67,高于37例胃肠间质瘤(82.56±7.45)和7例前列腺癌(4.76±0.98,均P〈0.05)。PRUNE2mRNA高表达的平滑肌肉瘤患者的生存期与低表达者比较,差异无统计学意义(X2=0.96,P=0.326)。PRUNE2mRNA高表达的胃肠间质瘤患者的生存期与低表达者比较,差异无统计学意义(X2=3.10,P=0.078)。平滑肌肉瘤中PcA3mRNA平均表达水平为26.38±3.04,低于前列腺癌(3272.00±240.87,P=0.004)。在平滑肌肉瘤中,PCA3mRNA与PRUNE2mRNA的表达呈正相关(r=0.901,P〈0.001)。结论PRUNE2的表达与平滑肌肉瘤患者的生存期有关,PCA3的表达与PRUNE2mRNA的表达呈正相关。 | 杨吉龙 David Cogdell James Eddy Jonathan Trent Nathan Price ZHANG Wei | 2012 | 中华肿瘤杂志2012，34，7： | 2 |
| 9 | Soluble TNF-α receptor 1 and IL-6 plasma levels in humans subjected to the sleep deprivation model of spaceflight显示文摘 | William T. Shearer James M. Reuben Janet M. Mullington Nicholas J. Price Bang-Ning Lee E.O’Brian Smith Martin P. Szuba Hans P.A. Van Dongen David F. Dinges | 2001 | The Journal of Allergy and Clinical Immunology2001，，1： | 2 |
| 10 | Increasing background ozone during spring on the west coast of North America显示文摘 | Daniel Jaffe Heather Price David Parrish | 2003 | Geophysical Research Letters2003，30，12： | 1 |
| 11 | Accelerated Amyloid Deposition in the Brains of Transgenic Mice Coexpressing Mutant Presenilin 1 and Amyloid Precursor Proteins显示文摘 | David R Borchelt Tamara Ratovitski Judy van Lare Michael K Lee Vicki Gonzales Nancy A Jenkins Neal G Copeland Donald L Price Sangram S Sisodia | 1997 | Neuron1997，，4： | 1 |
| 12 | Hack-a-Vote: Security issues with electronic voting systems显示文摘 | Jonathan Bannet David W Price Algis Rudys | 2004 | IEEE Security and Privacy Magazine2004，2，1： | 1 |
| 13 | Biphenyl-and fluorenyl-based potential molecular electronic devices 显示文摘 | David W Price Jr James M Tour | 2003 | Tetrahedron2003，59，： | 1 |
| 14 | Comparison of the effects of di-(2-ethylhexyl)adipate on hepatic peroxisome proliferation and cell replication in the rat and mouse 1 Presented in part at the Annual Meeting of the Society of Toxicology, Dallas, Texas, March 13–17, 1994. 1显示文摘 | Brian G Lake Roger J Price Morag E Cunninghame David G Walters | 1997 | Toxicology1997，，3： | 1 |
| 15 | Perceptions, impactand management of asthma in South Africa: a patient ques-tionnaire study 显示文摘 | Robin Green Gloria Davis David Price | 2008 | J Primary Care Respiratory2008，17，4： | 1 |
| 16 | Advances in parabolic trough solar power technology显示文摘 | Price Hank Eckhard Ltipfert David Kearney | 2002 | Journal of Solar Energy Engineering2002，124，： | 1 |
| 17 | Glycosylation of the enhanced aromatic sequon is similarly stabilizing in three distinct reverse turn contexts显示文摘 | Joshua L Price David L Powers Evan T Powers | 2011 | Proceedings of the National Academy of Sciences2011，108，14： | 1 |
| 18 | The Future of Peptide‐based Drugs显示文摘 | David J. Craik David P. Fairlie Spiros Liras David Price | 2012 | Chemical Biology & Drug Design2012，，1： | 1 |
| 19 | Advances in Parabolic Trough Solar Power Technology 显示文摘 | PRICE H LUPFERT E DAVID K | 2002 | Journal of Solar Energy Engineering2002，1，： | 1 |
| 20 | Ab Initio Lattice Dynamics and Structural Stability of MgO 显示文摘 | Artem R Oganov Michael J Gillan G David Price | 2003 | Journal of Chemical Physics2003，118，10： | 1 |
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