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| 1 | Laparoscopic appendectomy for acute appendicitis: How to discourage surgeons using inadequate therapy显示文摘Acute appendicitis(AA) develops in a progressive and irreversible manner, even if the clinical course of AA can be temporarily modified by intentional medications. Reliable and real-time diagnosis of AA can be made based on findings of the white blood cell count and enhanced computed tomography. Emergent laparoscopic appendectomy(LA) is considered as the first therapeutic choice for AA. Interval/delayed appendectomy at 6-12 wk after disease onset is considered as unsafe with a high recurrent rate during the waiting time. However, this technique may have some advantages for avoiding unnecessary extended resection in patients with an appendiceal mass. Nonoperative management of AA may be tolerated only in children. Postoperative complications increase according to the patient's factors, and temporal avoidance of emergent general anesthesia may be beneficial for high-risk patients. The surgeon's skill and cooperation of the hospital are important for successful LA. Delaying appendectomy for less than 24 h from diagnosis is safe. Additionally, a semi-elective manner(i.e., LA within 24 h after onset of symptoms) may be paradoxically acceptable, according to the factors of the patient, physician, and institution. Prompt LA is mandatory for AA. Fortunately, the Japanese government uses a universal health insurance system, which covers LA. | tomohide hori takafumi machimoto yoshio kadokawa toshiyuki hata tatsuo ito shigeru kato daiki yasukawa yuki aisu yusuke kimura maho sasaki yuichi takamatsu taku kitano shigeo hisamori tsunehiro yoshimura | 2017 | World Journal of Gastroenterology2017，23，32： | 18 |
| 2 | Laparoscopic and endoscopic cooperative surgery for gastric tumors: Perspective for actual practice and oncological benefits显示文摘Laparoscopic and endoscopic cooperative surgery(LECS) is a surgical technique that combines laparoscopic partial gastrectomy and endoscopic submucosal dissection. LECS requires close collaboration between skilled laparoscopic surgeons and experienced endoscopists. For successful LECS, experience alone is not sufficient. Instead, familiarity with the characteristics of both laparoscopic surgery and endoscopic intervention is necessary to overcome various technical problems. LECS was developed mainly as a treatment for gastric submucosal tumors without epithelial lesions, including gastrointestinal stromal tumors(GISTs). Local gastric wall dissection without lymphadenectomy is adequate for the treatment of gastric GISTs. Compared with conventional simple wedge resection with a linear stapler, LECS can provide both optimal surgical margins and oncological benefit that result in functional preservation of the residual stomach. As technical characteristics, however, classic LECS involves intentional opening of the gastric wall, resulting in a risk of tumor dissemination with contamination by gastric juice. Therefore, several modified LECS techniques have been developed to av-oid even subtle tumor exposure. Furthermore, LECS for early gastric cancer has been attempted according tothe concept of sentinel lymph node dissection. LECS is a prospective treatment for GISTs and might become a future therapeutic option even for early gastric cancer. Interventional endoscopists and laparoscopic surgeons collaboratively explore curative resection. Simultaneous intraluminal approach with endoscopy allows surgeons to optimizes the resection area. LECS, not simple wedge resection, achieves minimally invasive treatment and allows for oncologically precise resection. We herein present detailed tips and pitfalls of LECS and discuss various technical considerations. | Yuki Aisu Daiki Yasukawa Yusuke Kimura Tomohide Hori | 2018 | World Journal of Gastrointestinal Oncology2018，10，11： | 15 |
| 3 | Eosinophilic gastroenteritis with cytomegalovirus infection in an immunocompetent child显示文摘A 3-year-old boy developed transient protein-losing gastroenteropathy associated with cytomegalovirus (CMV) infection. Both IgG and IgM antibodies to CMV were positive in a serologic blood test. Upper gastrointestinal endoscopy showed multiple erosions throughout the body of the stomach, without enlarged gastric folds. Histological examination of the biopsy specimens indicated eosinophilic gastroenteritis and CMV infection. The patient had complete resolution without specific therapy for CMV in four weeks. An allergic reaction as well as CMV infection played important roles in the pathogenesis of this case. | Junji Takeyama Daiki Abukawa Katsushi Miura | 2007 | World Journal of Gastroenterology2007，13，34： | 11 |
| 4 | Nutritional status in relation to lifestyle in patients with compensated viral cirrhosis显示文摘AIM:To assess the nourishment status and lifestyle of non-hospitalized patients with compensated cirrhosis by using noninvasive methods.METHODS:The subjects for this study consisted of 27 healthy volunteers,59 patients with chronic viral hepatitis,and 74 patients with viral cirrhosis,from urban areas.We assessed the biochemical blood tests,anthropometric parameters,diet,lifestyle and physical activity of the patients.A homeostasis model assessment-insulin resistance(HOMA-IR) value of ≥ 2.5 was considered to indicate insulin resistance.We measured height,weight,waist circumference,arm circumference,triceps skin-fold thickness,and handgrip strength,and calculated body mass index,arm muscle circumference(AMC),and arm muscle area(AMA).We interviewed the subjects about their dietary habits and lifestyle using health assessment computer software.We surveyed daily physical activity using a pedometer.Univariate and multivariate logistic regression modeling were used to identify the relevant factors for insulin resistance.RESULTS:The rate of patients with HOMA-IR ≥ 2.5(which was considered to indicate insulin resistance) was 14(35.9%) in the chronic hepatitis and 17(37.8%) in the cirrhotic patients.AMC(%)(control vs chronic hepatitis,111.9% ± 10.5% vs 104.9% ± 10.7%,P = 0.021;control vs cirrhosis,111.9% ± 10.5% vs 102.7% ± 10.8%,P = 0.001) and AMA(%)(control vs chronic hepatitis,128.2% ± 25.1% vs 112.2% ± 22.9%,P = 0.013;control vs cirrhosis,128.2% ± 25.1% vs 107.5% ± 22.5%,P = 0.001) in patients with chronic hepatitis and liver cirrhosis were significantly lower than in the control subjects.Handgrip strength(%) in the cirrhosis group was significantly lower than in the controls(control vs cirrhosis,92.1% ± 16.2% vs 66.9% ± 17.6%,P < 0.001).The results might reflect a decrease in muscle mass.The total nutrition intake and amounts of carbohydrates,protein and fat were not significantly different amongst the groups.Physical activity levels(kcal/d)(control vs cirrhosis,210 ± 113 kcal/d vs 125 ± 74 kcal/d,P = 0.001),number of steps(step/d)(control vs cirrhosis,8070 ±3027 step/d vs 5789 ± 3368 step/d,P = 0.011),and exercise(Ex)(Ex/wk)(control vs cirrhosis,12.4 ± 9.3 Ex/wk vs 7.0 ± 7.7 Ex/wk,P = 0.013) in the cirrhosis group was significantly lower than the control group.The results indicate that the physical activity level of the chronic hepatitis and cirrhosis groups were low.Univariate and multivariate logistic regression modeling suggested that Ex was associated with insulin resistance(odds ratio,6.809;95% CI,1.288-36.001;P = 0.024).The results seem to point towards decreased physical activity being a relevant factor for insulin resistance.CONCLUSION:Non-hospitalized cirrhotic patients may need to maintain an adequate dietary intake and receive lifestyle guidance to increase their physical activity levels. | Fumikazu Hayashi Chika Momoki Miho Yuikawa Yuko Simotani Etsushi Kawamura Atsushi Hagihara Hideki Fujii Sawako Kobayashi Shuji Iwai Hiroyasu Morikawa Masaru Enomoto Akihiro Tamori Norifumi Kawada Satoko Ohfuji Wakaba Fukusima Daiki Habu | 2012 | World Journal of Gastroenterology2012，18，40： | 11 |
| 5 | Crucial anatomy and technical cues for laparoscopic transabdominal preperitoneal repair: Advanced manipulation for groin hernias in adults显示文摘Groin hernias include indirect inguinal, direct inguinal, and femoral hernias. Obturator and supravesical hernias appear very close to the groin. High-quality repairs are required for groin hernias. The concept of 'tension-free repair' is generally accepted, and surgical repairs with mesh are categorized as 'hernioplasties'. Surgeons should have good knowledge of the relevant anatomy. Physicians generally focus on the preperitoneal space, myopectineal orifice, topographic nerves, and regional vessels. Currently, laparoscopic surgery has therapeutic potential in the surgical setting for hernioplasty, with laparoscopic transabdominal preperitoneal(TAPP) repair appearing to be a powerful tool for use in adult hernia patients. TAPP offers the advantages of accurate diagnoses, repair of bilateral and recurrent hernias, less postoperative pain, early recovery allowing work and activities, tension-free repair of the preperitoneal(posterior) space, ability to cover obturator hernias, and avoidance of potential injury to the spermatic cord. The disadvantages of TAPP are the need for general anesthesia, adhering to a learning curve, higher cost, unexpected complications related to abdominal organs, adhesion to the mesh, unexpected injuries to vessels, prolonged operative time, and as-yet-unknown long-term outcomes. Both technical skill and anatomical familiarity are important for safe, reliable surgery. With increasing awareness of the importance of anatomy during TAPP repair, we address the skills and pitfalls during laparoscopic TAPP repair in adult patients using illustrations and schemas. We also address debatable points on this subject. | Daiki Yasukawa Yuki Aisu Tomohide Hori | 2020 | World Journal of Gastrointestinal Surgery2020，12，7： | 11 |
| 6 | Systemic gemcitabine combined with intra-arterial low-dose cisplatin and 5-fluorouracil for advanced hepatocellular carcinoma: Seven cases显示文摘The combination of intra-arterial low-dose cisplatin and 5-fluorouracil (5-FU) is effective against advanced hepatocellular carcinoma (HCC). Systemic gemcitabine chemotherapy seems effective in many cancers. We report the results of combination therapy with systemic gemcitabine, intra-arterial low-dose cisplatin and 5-FU (GEMFP). Seven patients with non-resectable advanced HCC were treated with GEMFP. One course of chemotherapy consisted of daily intra-arterial cisplatin (20 mg/body weight/hour on d 1, 10 mg/body weight per 0.5 h on d 2-5 and 8-12), followed by 5-FU (250 mg/body weight per 5 h on d 1-5 and 8-12) via an injection port. Gemcitabine at 1000 mg/m2 was administered intravenously at 0.5 h on d 1 and 8. The objective response was 57%. The response to GEMFP was as follows: complete response (no patients), partial response (four patients), stable disease (three patients), and progressive disease (no patients). The median survival period was 8 mo (range, 5-55). With regard to the National Cancer Institute Common Toxicity Criteria (NCI-CTC) grade 3 or 4 adverse reactions, seven (100%), seven, six (86%) and one (14%) patients developed leukopenia, neutropenia, thrombocytopenia and anemia, respectively. GEMFP may potentially be effective for non- resectable advanced HCC, but it has severe hematologic toxicity. | Kiminori Uka Hiroshi Aikata Shintaro Takaki Tomokazu Kawaoka Hiromi Saneto Daiki Miki Shoichi Takahashi Naoyuki Toyota Katsuhide Ito Kazuaki Chayama | 2008 | World Journal of Gastroenterology2008，14，16： | 4 |
| 7 | Flow Range Enhancement by Secondary Flow Effect in Low Solidity Circular Cascade Diffusers显示文摘High-pressure ratio and wide operating range are highly required for compressors and blowers. The technical issue of the design is achievement of suppression of flow separation at small flow rate without deteriorating the efficiency at design flow rate. A numerical simulation is very effective in design procedure, however, cost of the numerical simulation is generally high during the practical design process, and it is difficult to confirm the optimal design which is combined with many parameters. A multi-objective optimization technique is the idea that has been proposed for solving the problem in practical design process. In this study, a Low Solidity circular cascade Diffuser(LSD) in a centrifugal blower is successfully designed by means of multi-objective optimization technique. An optimization code with a meta-model assisted evolutionary algorithm is used with a commercial CFD code ANSYS-CFX. The optimization is aiming at improving the static pressure coefficient at design point and at low flow rate condition while constraining the slope of the lift coefficient curve. Moreover, a small tip clearance of the LSD blade was applied in order to activate and to stabilize the secondary flow effect at small flow rate condition. The optimized LSD blade has an extended operating range of 114 % towards smaller flow rate as compared to the baseline design without deteriorating the diffuser pressure recovery at design point. The diffuser pressure rise and operating flow range of the optimized LSD blade are experimentally verified by overall performance test. The detailed flow in the diffuser is also confirmed by means of a Particle Image Velocimeter. Secondary flow is clearly captured by PIV and it spreads to the whole area of LSD blade pitch. It is found that the optimized LSD blade shows good improvement of the blade loading in the whole operating range, while at small flow rate the flow separation on the LSD blade has been successfully suppressed by the secondary flow effect. | Daisaku Sakaguchi Min Thaw Tun Kanata Mizokoshi Daiki Kishikawa | 2014 | Journal of Thermal Science2014，23，4： | 4 |
| 8 | 构建公铁货物一体化运输系统的基础分析显示文摘建立多种运输方式一体化运输系统要考虑一些基础要素,如货物特点、托运人和承运人的评价,及其运输网的通道条件等.货物特点决定了相关潜在需求和不同交通方式组合形成多式一体化运输的可能性.托运人和承运人的评价会对运输方式的选择产生重要影响.而运输网的通道条件要求各种运输方式改进相应的运输设备及服务.本文对这些要素进行对比分析,并讨论了形成公铁货物一体化运输系统的可能性及相关问题,最后,提出一些改进铁路货运服务的建议. | LI Guoquan TAMURA Kazuki MUTO Masai OKUDA Daiki | 2014 | 交通运输系统工程与信息2014，14，6： | 3 |
| 9 | Laparoscopic approach for choledochojejunostomy显示文摘Laparoscopic hepatobiliary and pancreatic (HBP) surgery has been developed slowly because of technical challenges and a protracted learning curve with the exception of laparoscopic cholecystectomy [1]. Surgical treatments for benign diseases of the extrahepatic bile duct (EHBD) are classified according to their therapeutic purpose as lithotomy (i.e., choledocholithotomy) or diversion (i.e., choledochojejunostomy)[2]. | Tomohide Hori Yuki Aisu Michihiro Yamamoto Daiki Yasukawa Taku Iida Shintaro Yagi Kentaro Taniguchi Shinji Uemoto | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，3： | 3 |
| 10 | Case of angina pectoris at rest and during effort due to coronary spasm and myocardial bridging显示文摘We present a case of a 71-year-old male who hadchest symptoms at rest and during effort. He had felt chest oppression during effort for 1 year,and his chest symptoms had recently worsened. One month before admission he felt chest squeezing at rest in the early morning. He presented at our institution to evaluate his chest symptoms. Electrocardiography and echocardiography failed to show any specific changes. Because of the possibility that his chest symptoms were due to myocardial ischemia,he was admitted to our institution for coronary angiography(CAG). An initial CAG showed mild atherosclerotic changes in the proximal segment of the left anterior descending coronary artery(LAD) and mid-segment of the left circumflex coronary artery. Subsequent spasm provocation testing using acetylcholine revealed a bilateral coronary vasospasm,which was relieved after the intracoronary infusion of nitroglycerin. Finally,a CAG showed myocardial bridging(MB) of the mid-distal segments of the LAD. Fractional flow reserve using the intravenous administration of adenosine triphosphate was positive at 0.77,which jumped up to 0.90 through the myocardial bridging segments when the pressure wire was pulled back. Thus,coronary vasospasm and MB might have contributed to his chest symptoms at rest and during effort. Interventional cardiologists should consider the presence of MB as a potential cause of myocardial ischemia. | Hiroki Teragawa Yuichi Fujii Tomohiro Ueda Daiki Murata Shuichi Nomura | 2015 | World Journal of Cardiology2015，7，6： | 3 |
| 11 | Protocol for laparoscopic cholecystectomy: Is it rocket science?显示文摘Laparoscopic cholecystectomy(LC) does not require advanced techniques, and its performance has therefore rapidly spread worldwide. However, the rate of biliary injuries has not decreased. The concept of the critical view of safety(CVS) was first documented two decades ago. Unexpected injuries are principally due to misidentification of human factors. The surgeon's assumption is a major cause of misidentification, and a high level of experience alone is not sufficient for successful LC. We herein describe tips and pitfalls of LC in detail and discuss various technical considerations.Finally, based on a review of important papers and our own experience, we summarize the following mandatory protocol for safe LC:(1) consideration that a high level of experience alone is not enough;(2) recognition of the plateau involving the common hepatic duct and hepatic hilum;(3) blunt dissection until CVS exposure;(4) Calot's triangle clearance in the overhead view;(5) Calot's triangle clearance in the view from underneath;(6) dissection of the posterior right side of Calot's triangle;(7) removal of the gallbladder body; and(8) positive CVS exposure. We believe that adherence to this protocol will ensure successful and beneficial LC worldwide, even in patients with inflammatory changes and rare anatomies. | Tomohide Hori Fumitaka Oike Hiroaki Furuyama Takafumi Machimoto Yoshio Kadokawa Toshiyuki Hata Shigeru Kato Daiki Yasukawa Yuki Aisu Maho Sasaki Yusuke Kimura Yuichiro Takamatsu Masato Naito Masaya Nakauchi Takahiro Tanaka Daigo Gunji Kiyokuni Nakamura Kiyoko Sato Masahiro Mizuno Taku Iida Shintaro Yagi Shinji Uemoto Tsunehiro Yoshimura | 2016 | World Journal of Gastroenterology2016，22，47： | 3 |
| 12 | Comparison of cerebral activation between motor execution and motor imagery of self-feeding activity显示文摘Motor imagery is defined as an act wherein an individual contemplates a mental action of motor execution without apparent action.Mental practice executed by repetitive motor imagery can improve motor performance without simultaneous sensory input or overt output.We aimed to investigate cerebral hemodynamics during motor imagery and motor execution of a self-feeding activity using chopsticks.This study included 21 healthy right-handed volunteers.The self-feeding activity task comprised either motor imagery or motor execution of eating sliced cucumber pickles with chopsticks to examine eight regions of interest:pre-supplementary motor area,supplementary motor area,bilateral prefrontal cortex,premotor area,and sensorimotor cortex.The mean oxyhemoglobin levels were detected using near-infrared spectroscopy to reflect cerebral activation.The mean oxyhemoglobin levels during motor execution were significantly higher in the left sensorimotor cortex than in the supplementary motor area and the left premotor area.Moreover,significantly higher oxyhemoglobin levels were detected in the supplementary motor area and the left premotor area during motor imagery,compared to motor execution.Supplementary motor area and premotor area had important roles in the motor imagery of self-feeding activity.Moreover,the activation levels of the supplementary motor area and the premotor area during motor execution and motor imagery are likely affected by intentional cognitive processes.Levels of cerebral activation differed in some areas during motor execution and motor imagery of a self-feeding activity.This study was approved by the Ethical Review Committee of Nagasaki University(approval No.18110801)on December 10,2018. | Moemi Matsuo Naoki Iso Kengo Fujiwara Takefumi Moriuchi Daiki Matsuda Wataru Mitsunaga Akira Nakashima Toshio Higashi | 2021 | Neural Regeneration Research2021，16，4： | 3 |
| 13 | The performance of variance ratio unit root tests under nonlinear stationary TAR and STAR processes:evidence from Monte-Carlo simulations and application显示文摘 | Daiki Maki | 2008 | Computation Economics2008，31，1： | 1 |
| 14 | Pretreatment predictor of response, time to progression, and survival to intraarterial 5-fluorouracil/interferon combination therapy in patients with advanced hepatocellular carcinoma显示文摘 | Kiminori Uka Hiroshi Aikata Shintaro Takaki Daiki Miki Tomokazu Kawaoka Soo Cheol Jeong Shoichi Takahashi Naoyuki Toyota Katsuhide Ito Kazuaki Chayama | 2007 | Journal of Gastroenterology2007，，10： | 1 |
| 15 | Natural course of portal hemodynamics in patients with chronic liver diseases, evaluated by per-rectal portal scintigraphy with Tc-99m pertechnetate显示文摘 | Susumu Shiomi Nobumitsu Sasaki Daiki Habu Tadashi Takeda Shuhei Nishiguchi Tetsuo Kuroki Takashi Tanaka Hironobu Ochi | 1998 | Journal of Gastroenterology1998，，4： | 1 |
| 16 | The nanoparticulation by octaarginine-modified liposome improves α-galactosylceramide-mediated antitumor therapy via systemic administration显示文摘 | Takashi Nakamura Daiki Yamazaki Jun Yamauchi Hideyoshi Harashima | 2013 | Journal of Controlled Release2013，，2： | 1 |
| 17 | Finite-difference time-domain simulation of partial discharges in a gas insulated switchgear显示文摘It is important to estimate the current magnitude and charge amount of a partial discharge (PD) in a gasinsulatedswitchgear (GIS). In this study, electromagnetic fields generated by a PD in an 84 kV-class three-phase GIS fortesting have been measured with a voltage probe installed on the outer surface of an insulation spacer of the GIS tank,and the corresponding simulations have been carried out using the three-dimensional finite-difference time-domain(FDTD) method. FDTD-computed time-domain voltages across spacers agree reasonably well with the correspondingmeasured ones, and the current magnitude of PD and its charge amount have been estimated. | Hiroki Tanaka Daiki Tanahashi Yoshihiro Baba Naoto Nagaoka Naoki Okada Hideto Ohki Masayasu Takeuchi | 2016 | High Voltage2016，1，1： | 1 |
| 18 | Diagnostic accuracy of the 13 C-urea breath test for childhood Helicobacter pylori infection: a multicenter Japanese study显示文摘 | Seiichi Kato Kyoko Ozawa Mutsuko Konno Hitoshi Tajiri Norikazu Yoshimura Toshiaki Shimizu Takuji Fujisawa Daiki Abukawa Takanori Minoura Kazuie Iinuma | 2002 | The American Journal of Gastroenterology2002，，： | 1 |
| 19 | IL28B polymorphism is associated with fatty change in the liver of chronic hepatitis C patients显示文摘 | Mayu Ohnishi Masataka Tsuge Tomohiko Kohno Yizhou Zhang Hiromi Abe Hideyuki Hyogo Yuki Kimura Daiki Miki Nobuhiko Hiraga Michio Imamura Shoichi Takahashi Hidenori Ochi C. Hayes Shinji Tanaka Koji Arihiro Kazuaki Chayama | 2012 | Journal of Gastroenterology2012，，7： | 1 |
| 20 | Fatigue strength of newly developed high-strength low alloy TRIP-aided steels with good hardenability 显示文摘 | Koh-ichi Sugimoto Daiki Fiji Nobuo Yoshikaw | 2010 | Procedia Engineering2010，，2： | 1 |
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