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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Characterizations and mechanical properties of impregnated diamond segment using Cu-Fe-Co metal matrix显示文摘Diamond impregnated Cu-Fe-Co based saw-blade segments are directly processed by vacuum and pressure-assisted sintering at different temperature,with the purpose of reducing the cobalt content in diamond tools.Copper and iron are used as the bonding elements and co-balt-chrome pre-alloyed powder is used as the hardening phase.Effects of sintering temperature on microstructures and mechanical properties of the sintered matrix and diamond graphitization were investigated by X-ray diffraction analysis,electron probe micro-analyzer,universal testing machine,digital Rockwell hardness tester and Raman scattering analyzer.Results showed that microstructures of the sintered matrix were refined and porosities in the sintered matrix were closed to a more spherical-like shape with the increase of the sintering temperature.Densification,hardness and tensile strength of the matrix sintered at 820 ℃ were 12.75%,2.72% and 156.38% higher than that of the matrix sintered at 740 ℃,respectively.Diamond graphitization was not occurred at 820 ℃.The hardness and the tensile strength rose 32.8% and 13.5%,respectively,after 7.5 h ageing treatment.The matrix densification ascent and the dispersed distribution of Co-Cr pre-alloyed powders contributed a hardness improvement and a tensile strength improvement to the Cu-Fe based matrix. | Li, Wensheng Zhang, Jie Wang, Shucai Dong, Hongfeng Li, Yaming Liu, Yi | 2012 | Rare Metals2012，31，1： | 19 |
| 3 | MicroRNAs regulate osteogenesis and chondrogenesis显示文摘 | Shiwu Dong Bo Yang Hongfeng Guo Fei Kang | 2012 | Biochemical and Biophysical Research Communications2012，，4： | 2 |
| 4 | Measurement-Based Channel Characterization for 5G Wireless Communications on Campus Scenario显示文摘The fifth generation(5G)communication has been a hotspot of research in recent years,and both research institutions and industrial enterprises put a lot of interests in 5G communications at some new frequency bands.In this paper,we investigate the radio channels of 5G systems below 6 GHz according to the 5G communication requirements and scenarios.Channel measurements were conducted on the campus of Beijing Jiaotong University,China at two key optional frequency bands below 6 GHz.By using the measured data,we analyzed key channel parameters at 460 MHz and 3.5 GHz,such as power delay profile,path loss exponent,shadow fading,and delay spread.The results are helpful for the 5G communication system design. | YANG Mi HE Ruisi AI Bo XIONG Lei DONG Honghui LI Jianzhi WANG Wei FAN Wei QIN Hongfeng | 2017 | ZTE Communications2017，15，1： | 2 |
| 5 | Piezoelectric PU/PVDF electrospun scaffolds for wound healing applications显示文摘 | GUO Hongfeng LI Zhensheng DONG Shiwu | 2012 | Colloids and Surfaces B2012，96，： | 1 |
| 6 | Comparable charge transport property based on S…S interactions with that of π-π stacking in a bis-fused tetrathiafulvalene compound显示文摘Compact molecular packing with short π-π stacking and large π-overlap in organic semiconductors is desirable for efficient charge transport and high carrier mobility.Thus charge transport anisotropy along different directions is commonly observed in organic semiconductors.Interestingly,in this article,we found that comparable charge transport property were achieved based on the single crystals of a bis-fused tetrathiafulvalene derivative(EM-TTP) compound along two interaction directions,that is,the multiple strong S…S intermolecular interactions and the π-π stacking direction,with the measured electrical conductivity and hole mobility of 0.4 S cm^(-1),0.94 cm^2 V^(-1) s^(-1) and 0.2 S cm^(-1),0.65 cm2 V^(-1) s^(-1),respectively.This finding provides us a new molecular design concept for developing novel organic semiconductors with isotropic charge transport property through the synergistic effect of multiple intermolecular interactions(such as S…S interactions) and π-π stacking. | Ke Zhou Hongfeng Chen Huanli Dong Qi Fang Wenping Hu | 2017 | Science China Chemistry2017，60，4： | 1 |
| 7 | Electrochemical catalytic activity of tungsten trioxide- modified graphite felt toward VO 2 + /VO 2+ redox reaction显示文摘 | Yang Shen Hongfeng Xu Pengcheng Xu Xiaoxin Wu Yiming Dong Lu Lu | 2014 | Electrochimica Acta2014，，： | 1 |
| 8 | Effects of sintering temperature on the properties of Cu-Co-based alloys matrix显示文摘 | LU Yang DONG Hongfeng LI Wensheng | 2011 | Advanced Materials Research2011，，24： | 1 |
| 9 | Iron-catalyzed one-pot reactions of o-aryloxybenzaldehydes to xanthones显示文摘An efficient one-pot procedure for the synthesis of multisubstituted xanthone derivatives using Fe-catalyzed reactions of 2-aryloxybenzaldehydes followed by DDQ(2,3-dichloro-5,6-dicyano-1,4-benzoquinone) oxidation has been developed.This method offers a convenient high-yield route to xanthones from easily accessible starting materials. | YANG JingYu DONG ChunYi LI HaiYan LI HongFeng LI YanZhong | 2012 | Chinese Science Bulletin2012，57，19： | 1 |
| 10 | Extraordinary high-temperature mechanical properties in binder-free nanopolycrystalline WC ceramic显示文摘From the perspective of high-temperature applications,materials with excellent high-temperature mechanical properties are always desirable.The present work demonstrates that the binder-free nanopolycrystalline WC ceramic with an average grain size of 103 nm obtained by high-pressure and hightemperature sintering exhibits excellent mechanical properties at both room temperature and high temperature up to 1000℃.Specifically,the binder-free nanopolycrystalline WC ceramic still maintains a considerably high Vicker hardness H_(V)of 23.4 GPa at 1000℃,which is only 22%lower than the room temperature H_(V).This outstanding thermo-mechanical stability is superior to that of typical technical ceramics,e.g.SiC,Si_(3)N_(4),Al_(2)O_(3),etc.Nanocrystalline grains with many dislocations,numerous low-energy,highly stableΣ2 grain boundaries,and a relatively low thermal expansion coefficient,are responsible for the observed outstanding high-temperature mechanical properties. | Hongfeng Dong Baozhong Li BoBo Liu Yang Zhang Lei Sun Kun Luo Yingju Wu Mengdong Ma Bing Liu Wentao Hu Julong He Dongli Yu Bo Xu Zhisheng Zhao Yongjun Tian | 2022 | Journal of Materials Science & Technology2022，，2： | 1 |
| 11 | Regulation of autophagic flux by CHIP显示文摘Autophagy is a major degradation system which processes substrates through the steps of autophagosome formation, autophagosome-lysosome fusion, and substrate degradation. Aberrant autophagic flux is present in many pathological conditions including neurodegeneration and tumors. CHIP/STUB1, an E3 ligase, plays an important role in neurodegeneration. In this study, we identified the regulation of autophagic flux by CHIP(carboxy-terminus of Hsc70-interacting protein). Knockdown of CHIP induced autophagosome formation through increasing the PTEN protein level and decreasing the AKT/m TOR activity as well as decreasing phosphorylation of ULK1 on Ser757. However, degradation of the autophagic substrate p62 was disturbed by knockdown of CHIP, suggesting an abnormality of autophagic flux. Furthermore, knockdown of CHIP increased the susceptibility of cells to autophagic cell death induced by bafilomycin A1. Thus, our data suggest that CHIP plays roles in the regulation of autophagic flux. | Dongkai Guo Zheng Ying Hongfeng Wang Dong Chen Feng Gao Haigang Ren Guanghui Wang | 2015 | Neuroscience Bulletin2015，31，4： | 1 |
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