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| 1 | Management of biliary complications after orthotopic liver transplantation:The role of endoscopy显示文摘Biliary complications are signifi cant causes of morbidity and mortality after orthotopic liver transplantation (OLT). The estimated incidence of biliary complications after OLT ranges between 10%-25%,however,these numbers continue to decline due to improvement in surgical techniques. The most common biliary complications are strictures (both anastomotic and non-anastomotic) and bile leaks. Most of these problems can be appropriately managed with endoscopic retrograde colangiography (ERC). Other complications such as bile duct stones,bile casts,sphincter of Oddi dysfunction,and hemobilia,are less frequent and also can be managed with ERC. This article will review the risk factors,diagnosis,and endoscopic management of the most common biliary complications after OLT. | Maria C Londoo Domingo Balderramo Andrés Cárdenas | 2008 | World Journal of Gastroenterology2008，14，4： | 22 |
| 2 | Nitric Oxide: A Multitasked Signaling Gas in Plants显示文摘 | Patricia Domingos Ana Margarida Prado Aloysius Wong Christoph Gehring Jose A. Feijo | 2015 | Molecular Plant2015，8，4： | 19 |
| 3 | Safety of once‐daily insulin detemir in patients with type 2 diabetes treated with oral hypoglycemic agents in routine clinical practice (在常规临床实践中使用口服降糖药治疗的2型糖尿病患者每日一次使用地特胰岛素治疗的安全性)显示文摘 | Stuart Ross Grzegorz Dzida Qiuhe Ji Marcel Kaiser Robert Ligthelm Luigi Meneghini Avideh Nazeri Domingo Orozco‐Beltran Changyu Pan Anne Louise Svendsen | 2014 | Journal of Diabetes2014，，3： | 18 |
| 4 | Wilson's disease:Revisiting an old friend显示文摘Wilson's disease(WD)is a rare condition caused by copper accumulation primarily in the liver and secondly in other organs,such as the central nervous system.It is a hereditary autosomal recessive disease caused by a deficiency in the ATP7B transporter.This protein facilitates the incorporation of copper into ceruloplasmin.More than 800 mutations associated with WD have been described.The onset of the disease frequently includes manifestations related to the liver(as chronic liver disease or acute liver failure)and neurological symptoms,although it can sometimes be asymptomatic.Despite it being more frequent in young people,WD has been described in all life stages.Due to its fatal prognosis,WD should be suspected in all patients with unexplained biochemical liver abnormalities or neurological or psychiatric symptoms.The diagnosis is established with a combination of clinical signs and tests,including the measurement of ceruloplasmin,urinary copper excretion,copper quantification in liver biopsy,or genetic assessment.The pharmacological therapies include chelating drugs,such as D-penicillamine or trientine,and zinc salts,which are able to change the natural history of the disease,increasing the survival of these patients.In some cases of end-stage liver disease or acute liver failure,liver transplantation must be an option to increase survival.In this narrative review,we offer an overview of WD,focusing on the importance of clinical suspicion,the correct diagnosis,and treatment. | Ana Lucena-Valera Domingo Perez-Palacios Rocio Muñoz-Hernandez Manuel Romero-Gómez Javier Ampuero | 2021 | World Journal of Hepatology2021，13，6： | 8 |
| 5 | Coexistence of papillary thyroid microcarcinoma and mucosa-associated lymphoid tissue lymphoma in a context of Hashimoto's thyroiditis显示文摘Papillary thyroid cancer(PTC)represents 80%-85%of thyroid cancer and its prevalence has been rising in the last decades.Primary thyroid lymphoma(PTL)accounts for 3%of extranodal lymphomas and about 5%of thyroid malignancies,having a prevalence of one or two cases per million people.Mucosa-Associated Lymphoid Tissue lymphoma represents approximately30%of PTL.Both entities have an indolent course and a very good prognosis.Diagnosis is made by ultrasound and fine needle aspiration(FNA)or surgery specimen pathology.They have also been associated with Hashimoto’s thyroiditis(HT),but pathogenesis and its links remains to be known.Treatment remains controversial and surgery is generally accepted in cases of disease limited to thyroid,as the present.Patients with thyroid nodules should be observed and followed.If there is an enlargement by ultrasound or clinical symptoms,FNA should be performed promptly.Patients with HT deserve additional surveillance,since this condition is associated with both PTC and PTL.In this case,the management with surgery and radioactive iodine ablation therapy was effective for both entities.Patients with thyroid nodules should be properly evaluated with ultrasound and thyroid function tests.If there is an enlargement of the neck,reported by symptoms or ultrasound,it requires further investigation.HT is associated to both PTC and PTL so if the enlargement of the nodules is on this context additional tests such as FNA should be performed.In this case,the patient was managed with surgery and radioactive iodine ablation therapy and it was effective for both entities. | Saul Levy-Blitchtein Stefany Plasencia-Rebata Domingo Morales Luna Juana del Valle Mendoza | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，8： | 5 |
| 6 | 广义坐标中动量算符的自伴性显示文摘本文旨在藉助希耳伯特空间算符理论方面的知识,澄清在量子力学书籍上通常出现的一些概念.在量子力学书籍里常常对有界和无界算符之间的基本区别不予理会.一个无界算符是对称(厄密)的条件并不足以使它成为自伴的,这一点经常被忽视.遗憾的是,量子力学里差不多所有的算符都是无界的.时常看到这样的叙述:对于任意线性算符A,我们可以写出厄密算符HA=(A+A+) /2,其中的厄密性被设想为具有自伴性的意义.沿着这条思路,在广义坐标里采取那种表述的动量算符的自伴性是有问题的.本文特别研究了运用球极坐标的重新描述,并且引出了与这些坐标相共轭的动量失去了自伴性的结论. | J. M. Domingos M. H. Caldeira | 1988 | 大学物理1988，0，2： | 4 |
| 7 | Adult stem cells in neural repair: Current options, limitations and perspectives显示文摘Stem cells represent a promising step for the future of regenerative medicine. As they are able to differentiate into any cell type, tissue or organ, these cells are great candidates for treatments against the worst diseasesthat defy doctors and researchers around the world. Stem cells can be divided into three main groups:(1) embryonic stem cells;(2) fetal stem cells; and(3) adult stem cells. In terms of their capacity for proliferation, stem cells are also classified as totipotent, pluripotent or multipotent. Adult stem cells, also known as somatic cells, are found in various regions of the adult organism, such as bone marrow, skin, eyes, viscera and brain. They can differentiate into unipotent cells of the residing tissue, generally for the purpose of repair. These cells represent an excellent choice in regenerative medicine, every patient can be a donor of adult stem cells to provide a more customized and efficient therapy against various diseases, in other words, they allow the opportunity of autologous transplantation. But in order to start clinical trials and achieve great results, we need to understand how these cells interact with the host tissue, how they can manipulate or be manipulated by the microenvironment where they will be transplanted and for how long they can maintain their multipotent state to provide a full regeneration. | Eric Domingos Mariano Manoel Jacobsen Teixeira Suely Kazue Nagahashi Marie Guilherme Lepski | 2015 | World Journal of Stem Cells2015，7，2： | 3 |
| 8 | 婴儿常见胃肠道症状的实用处理法则(一)显示文摘在婴儿,特别是配方奶喂养的婴儿中功能性胃肠道(GI)症状较为常见[1]。应对这一问题,儿科医师常采用更换配方奶的方式来处理。由于治疗婴儿功能性GI症状的双盲的、安慰剂对照的、前瞻性干预的试验非常有限,本文在世界各地儿童胃肠病专科医师和过敏症专科医师一致意见的基础上,制定了婴儿常见GI的实用处理法则,并具体介绍各种婴幼儿. | Yvan Vandenplas Pedro Gutierrez-Castrellon Carlos Velasco-Benitez Jorge Palacios Domingo Jaen Hugo Ribeiro Lynette Pei-Chi Shek Bee-Wah Lee Pedro Alarcon | 2013 | 临床儿科杂志2013，31，7： | 3 |
| 9 | Heart rate variability to assess ventilatory thresholds in professional basketball players显示文摘Purpose: The aim of this study was to determine if heart rate variability(HRV) during incremental test could be used to estimate ventilatory threshold(VT) in professional basketball players, with sufficient precision to be used in their training. Furthermore, the second aim was to analyse the association between HRV and 3 methods of VT determination by gas analysis.Methods: Twenty-four professional basketball players(age: 23.4 ± 4.9 years; height: 195.4 ± 9.8 cm; body mass: 92.2 ± 11.9 kg) performed an incremental running test to exhaustion. First ventilatory threshold(VT1) was determined by ventilatory equivalent(VE) and HRV and second ventilatory threshold(VT2) was determined by 3 methods of gases analysis(V-slope, VE and gas exchange ratio(R), and HRV). Pearson's coefficient(r) was used to detect differences between data and the strength of each relationship. The mean of absolute differences and Bland–Altman analysis were used to evaluate whether there was agreement.Results: The results showed no significant differences in HR and oxygen consumption(VO2) at VT1 between the 2 methods. Furthermore, no significant differences among the methods of gases analysis and HRV were observed in speed, HR, and VO2 at VT2. Moreover, VTs estimated using HRV and gas methods were significantly correlated. Correlation in HR values was higher between R and HRV(r = 0.96) and VE and HRV(r = 0.96) than V-slope and HRV(r = 0.90).Conclusion: These findings provide a practical, inexpensive approach for evaluating specific training loads when determining VT2 in basketball players. Therefore, HRV is an alternative method to determine VT2 without the application of expensive technology that limits its use to laboratories. | Domingo Jesús Ramos-Campo Jacobo A. Rubio-Arias Vicente Avila-Gandia Cristian Marin-Pagan Antonio Luque Pedro E. Alcaraz | 2017 | Journal of Sport and Health Science2017，6，4： | 3 |
| 10 | Boosting k -nearest neighbor classifier by means of input space projection显示文摘 | Nicolás García-Pedrajas Domingo Ortiz-Boyer | 2009 | Expert Systems With Applications2009，，7： | 3 |
| 11 | The influence of transforming growth factor‐α, cyclooxygenase‐2, matrix metalloproteinase (MMP)‐7, MMP‐9 and CXCR4 proteins involved in epithelial–mesenchymal transition on overall survival of patients with gastric cancer显示文摘 | Marcello Ferretti Fanelli Ludmilla T Domingos Chinen Maria Dirlei Begnami Wilson Luis Costa José Humberto T Fregnami Fernando A Soares André Luis Montagnini | 2012 | Histopathology2012，，2： | 2 |
| 12 | Current management of biliary complications after liver transplantation: Emphasis on endoscopic therapy显示文摘 | Domingo Balderramo Miguel Navasa Andres Cardenas | 2010 | Gastroenterologia y Hepatologia2010，，2： | 2 |
| 13 | Genome-wide Introgression Lines and their Use in Genetic and Molecular Dissection of Complex Phenotypes in Rice (Oryza sativa L.)显示文摘 | Zhi-Kang Li Bin-Ying Fu Yong-Ming Gao Jian-Long Xu J. Ali H. R. Lafitte Yun-Zhu Jiang J. Domingo Rey C. H. M. Vijayakumar R. Maghirang Tian-Qing Zheng Ling-Hua Zhu | 2005 | Plant Molecular Biology2005，，1： | 2 |
| 14 | Evaluation of biodegradable electric conductive tube-guides and mesenchymal stem cells显示文摘AIM: To study the therapeutic effect of three tubeguides with electrical conductivity associated to mesenchymal stem cells(MSCs) on neuro-muscular regeneration after neurotmesis.METHODS: Rats with 10-mm gap nerve injury were tested using polyvinyl alcohol(PVA), PVA-carbon nanotubes(CNTs) and MSCs, and PVA-polypyrrole(PPy). The regenerated nerves and tibialis anterior muscles were processed for stereological studies after 20 wk. The functional recovery was assessed serially for gait biomechanical analysis, by extensor postural thrust, sciatic functional index and static sciatic functionalindex(SSI), and by withdrawal reflex latency(WRL). In vitro studies included cytocompatibility, flow cytometry, reverse transcriptase polymerase chain reaction and karyotype analysis of the MSCs. Histopathology of lung, liver, kidneys, and regional lymph nodes ensured the biomaterials biocompatibility. RESULTS: SSI remained negative throughout and independently from treatment. Differences between treted groups in the severity of changes in WRL existed, showing a faster regeneration for PVA-CNTs-MSCs(P < 0.05). At toe-off, less acute ankle joint angles were seen for PVA-CNTs-MSCs group(P = 0.051) suggesting improved ankle muscles function during the push off phase of the gait cycle. In PVA-PPy and PVA-CNTs groups, there was a 25% and 42% increase of average fiber area and a 13% and 21% increase of the 'minimal Feret's diameter' respectively. Stereological analysis disclosed a significantly(P < 0.05) increased myelin thickness(M), ratio myelin thickness/axon diameter(M/d) and ratio axon diameter/fiber diameter(d/D; g-ratio) in PVA-CNT-MSCs group(P < 0.05). CONCLUSION: Results revealed that treatment with MSCs and PVA-CNTs tube-guides induced better nerve fiber regeneration. Functional and kinematics analysis revealed positive synergistic effects brought by MSCs and PVA-CNTs. The PVA-CNTs and PVA-PPy are promising scaffolds with electric conductive properties, bio- and cytocompatible that might prevent the secondary neurogenic muscular atrophy by improving the reestablishment of the neuro-muscular junction. | Jorge Ribeiro Tiago Pereira Ana Rita Caseiro Paulo Armada-da-Silva Isabel Pires Justina Prada Irina Amorim Sandra Amado Miguel Franca Carolina Goncalves Maria Ascensao Lopes Jose Domingos Santos Dina Morais Silva Stefano Geuna Ana Lúcia Luís Ana Colette Maurício | 2015 | World Journal of Stem Cells2015，7，6： | 2 |
| 15 | Trochanteric fractures treated with a proximal femoral nail显示文摘 | L. Domingo D. Cecilia A. Herrera C. Resines | 2001 | International Orthopaedics2001，，5： | 2 |
| 16 | Do current anti-cyberloafing disciplinary practices have a replica in research findings?: A study of the effects of coercive strategies on workplace Internet misuse显示文摘 | Pablo Zoghbi Manrique de Lara Domingo Verano Tacoronte Jyh-Ming Ting Ding | 2006 | Internet Research2006，，4： | 2 |
| 17 | Aortic valve stenosis provides complementary information to bleeding risk scores in non-valvular atrial fibrillation patients initiating anticoagulation显示文摘Background The identification of modifiable bleeding risk factors may be of relevance.The aim is to evaluate if aortic stenosis(AS)provides additional information to bleeding risk scores for predicting major bleeding(MB)in non-valvular atrial fibrillation(AF).Methods We designed a retrospective multi-center study including 2880 consecutive non-valvular AF patients initiating oral anticoagulation between January 2013 and December 2016.AS was defined as moderate or severe according to European echocardiography guidelines criteria.HASBLED,ATRIA and ORBIT scores were used to evaluate the bleeding risk.MB was defined according to the International Society on Thrombosis and Haemostasia criteria and registered at 18 months of follow-up.Results 168(5.8%)patients had AS.Patients with AS had higher risk for MB compared to those without AS(HR=2.13,95%CI:1.40-3.23,P<0.001).Patients without AS and low-intermediate bleeding risk(0 points)showed the lowest MB rate,whereas the MB rate observed among patients with AS and high bleeding risk(2 points)was the highest one.Discrimination and reclassification analyses showed that AS provided additional information to bleeding risk scores for predicting MB at 18 months of follow-up.Conclusions In this population,AS was associated with an increased risk for MB at midterm follow-up.The three scoring systems showed a moderate discriminatory ability for MB.Moreover,the addition of AS was associated with a significant improvement in their predictive accuracy.We suggest that the presence of this valvulopathy should be taken into account for bleeding risk assessment. | Gines Elvira-Ruiz Cesar Caro-Martinez Pedro JoseFlores-Blanco Juan JoseCerezo-Manchado Helena Albendin-Iglesias Alejandro Lova-Navarro Francisco Arregui-Montoya Francisca Maria Munoz-Franco Natalia Garcia-Iniesta Arcadio Garcia-Alberola JoseLuis Bailen-Lorenzo Domingo Andres Pascual-Figal Sergio Manzano-Fernández | 2020 | Journal of Geriatric Cardiology2020，17，3： | 2 |
| 18 | A graph-based approach for the structural analysis of road and building layouts显示文摘A better understanding of the relationship between the structure and functions of urban and suburban spaces is one of the avenues of research still open for geographical information science.The research presented in this paper develops several graph-based metrics whose objective is to characterize some local and global structural properties that reflect the way the overall building layout can be cross-related to the one of the road layout.Such structural properties are modeled as an aggregation of parcels,buildings,and road networks.We introduce several computational measures(Ratio Minimum Distance,Minimum Ratio Minimum Distance,and Metric Compactness)that respectively evaluate the capability for a given road to be connected with the whole road network.These measures reveal emerging sub-network structures and point out differences between less-connective and moreconnective parts of the network.Based on these local and global properties derived from the topological and graph-based representation,and on building density metrics,this paper proposes an analysis of road and building layouts at different levels of granularity.The metrics developed are applied to a case study in which the derived properties reveal coherent as well as incoherent neighborhoods that illustrate the potential of the approach and the way buildings and roads can be relatively connected in a given urban environment.Overall,and by integrating the parcels and buildings layouts,this approach complements other previous and related works that mainly retain the configurational structure of the urban network as well as morphological studies whose focus is generally limited to the analysis of the building layout. | Mathieu Domingo Rémy Thibaud Christophe Claramunt | 2019 | Geo-Spatial Information Science2019，22，1： | 2 |
| 19 | A comparative study of the trochanteric fractures treated with Gamma nail or the proximal nail显示文摘 | Herrera A Domingo IJ Calvo A | 2002 | Int Orthop2002，26，： | 1 |
| 20 | Pyramiding of bacterial blight resistance genes in rice:marker-assisted selection using RFLP and PCR显示文摘 | Hunag N Angeles ER Domingo J | 1997 | Theor Appl Genet1997，95，： | 1 |
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