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| 1 | Sustained low diffusing capacity in hepatopulmonary syndrome after liver transplantation显示文摘AIM: To study the presence of sustained low diffusing capacity (DLCO) after liver transplantation (LT) in patients with hepatopulmonary syndrome (HPS).METHODS: Six patients with mild-to-severe HPS and 24 without HPS who underwent LT were prospectively followed before and after LT at mid-term (median, 15 mo). HPS patients were also assessed at long-tem (median, 86 mo).RESULTS: Before LT, HPS patients showed lower PaO2 (71 ± 8 mmHg), higher AaPO2 (43 ± 10 mmHg) and lower DLCO (54% ± 9% predicted), due to a combination of moderate-to-severe ventilation-perfusion (VA/Q) imbalance, mild shunt and diffusion limitation, than non-HPS patients (94 ± 4 mmHg and 19 ± 3 mmHg, and 85% ± 3% predicted, respectively) (P < 0.05 each). Seven non-HPS patients had also reduced DLCO (70% ± 4% predicted).At mid- and long-term after LT, compared to pre-LT, HPS patients normalized PaO2 (91 ± 3 mmHg and 87 ± 5 mmHg), AaPO2 (14 ± 3 mmHg and 23 ± 5 mmHg) and all VA/Q descriptors (P < 0.05 each) without changes in DLCO (53% ± 8% and 56% ± 7% predicted, respectively). Post-LT DLCO in non-HPS patients with pre-LT low DLCO was unchanged (75% ± 6% predicted).CONCLUSION: While complete VA/Q resolution in HPS indicates a reversible functional disturbance, sustained low DLCO after LT also present in some non-HPS patients, points to persistence of sub-clinical liver-induced pulmonary vascular changes. | Graciela Martínez-Pallí Federico P Gómez Joan A Barberà Miquel Navasa Josep Roca Robert Rodríguez-Roisin Felip Burgos Conchi Gistau | 2006 | World Journal of Gastroenterology2006，12，36： | 6 |
| 2 | Systemic, renal, and hepatic hemodynamic derangement in cirrhotic patients with spontaneous bacterial peritonitis显示文摘 | Luis Ruiz-del-Arbol Jesús Urman Javier Fernández Mónica González Miguel Navasa Alberto Monescillo Agustín Albillos Wladimiro Jiménez Vicente Arroyo | 2003 | Hepatology2003，，5： | 4 |
| 3 | Bacterial infections in cirrhosis: Epidemiological changes with invasive procedures and norfloxacin prophylaxis显示文摘 | Javier Fernández Miquel Navasa Juliá Gómez Jordi Colmenero Jordi Vila Vicente Arroyo Juan Rodés | 2002 | Hepatology2002，，1： | 3 |
| 4 | ARFI, FibroScan?, ELF, and their combinations in the assessment of liver fibrosis: A prospective study显示文摘 | Gonzalo Crespo Guillermo Fernández-Varo Zoe Mari?o Gregori Casals Rosa Miquel Stella M. Martínez Rosa Gilabert Xavier Forns Wladimiro Jiménez Miquel Navasa | 2012 | Journal of Hepatology2012，，2： | 3 |
| 5 | Current management of biliary complications after liver transplantation: Emphasis on endoscopic therapy显示文摘 | Domingo Balderramo Miguel Navasa Andres Cardenas | 2010 | Gastroenterologia y Hepatologia2010，，2： | 2 |
| 6 | Cost-effectiveness of enhanced liver fibrosis test to assess liver fibrosis in chronic hepatitis C virus and alcoholic liver disease patients显示文摘AIM To assess liver fibrosis(LF) in hepatitis C virus(HCV) and alcoholic liver disease(ALD), estimate health outcomes and costs of new noninvasive testing strategies METHODS A Markov model was developed to simulate LF progression in HCV and ALD for a cohort of 40-yearold men with abnormal levels of transaminases. Three different testing alternatives were studied: a single liver biopsy; annual Enhanced liver fibrosis(ELF?) followed by liver stiffness measurement(LSM) imaging as a confirmation test if the ELF test is positive; and annual ELF test without LSM. The analysis was performed from the perspective of a university hospital in Spain.Clinical data were obtained from published literature. Costs were sourced from administrative databases of the hospital. Deterministic and probabilistic sensitivity analyses were performed.RESULTS In HCV patients, annual sequential ELF test/LSM and annual ELF test alone prevented respectively 12.9 and 13.3 liver fibrosis-related deaths per 100 persons tested, compared to biopsy. The incremental costeffectiveness ratios(ICERs) were respectively €13400 and €11500 per quality-adjusted life year(QALY). In ALD, fibrosis-related deaths decreased by 11.7 and 22.1 per 100 persons tested respectively with sequential ELF test/LSM and annual ELF test alone. ICERs were €280 and €190 per QALY, respectively.CONCLUSION The use of the ELF test with or without a confirmation LSM are cost-effective options compared to a single liver biopsy for testing liver fibrosis in HCV and ALD patients in Spain. | Marcelo Soto Laura Sampietro-Colom Luis Lasalvia Aurea Mira Wladimiro Jiménez Miquel Navasa | 2017 | World Journal of Gastroenterology2017，23，17： | 2 |
| 7 | Renal Failure in Patients With Cirrhosis and Sepsis Unrelated to Spontaneous Bacterial Peritonitis: Value of MELD Score显示文摘 | Carlos Terra Mónica Guevara Aldo Torre Rosa Gilabert Javier Fernández Marta Martín-Llahí Maria E. Baccaro Miquel Navasa Conxita Bru Vicente Arroyo Juan Rodés Pere Ginès | 2005 | Gastroenterology2005，，6： | 2 |
| 8 | Norfloxacin vs Ceftriaxone in the Prophylaxis of Infections in Patients With Advanced Cirrhosis and Hemorrhage显示文摘 | Javier Fernández Luis Ruiz del Arbol Cristina Gómez Rosa Durandez Regina Serradilla Carlos Guarner Ramón Planas Vicente Arroyo Miguel Navasa | 2006 | Gastroenterology2006，，4： | 2 |
| 9 | Retransplantation in patients with hepatitis C recurrence after liver transplantation显示文摘 | José A. Carrión Miquel Navasa Xavier Forns | 2010 | Journal of Hepatology2010，，5： | 2 |
| 10 | Diagnosis, treatment and prophylaxis of spontaneous bacterial peritonitis: a consensus document显示文摘 | Antoni Rimola Guadalupe García-Tsao Miquel Navasa Laura J.V. Piddock Ramon Planas Brigitte Bernard John M. Inadomi | 2000 | Journal of Hepatology2000，，1： | 2 |
| 11 | Liver transplantasion in pations with non- biliary cirrhosis:prognostic valuc of preoperative factors显示文摘 | Gonzale EE Rimola A Navasa M ct al | 1998 | J Hepatol1998，28，： | 1 |
| 12 | Bacterial infections in cirrhosis:epidemiological changes with invasive procedures and norfloxacin prophylaxis显示文摘 | Fernandez J Navasa M Gomez J | 2002 | Hepatology2002，35，1： | 1 |
| 13 | Renal impairment after spontaneous bacterial peritonitis in cirrhosis: incidence、clinical course,predictive factors and prognosis显示文摘 | Follo A Llovet JM Navasa M | 1994 | Hepatology1994，20，： | 1 |
| 14 | Bactcrial transloeation of enteric organisma in patients with cirrhosis显示文摘 | Cirera I Bauer TM Navasa M | 2001 | Hepatology2001，34，： | 1 |
| 15 | Regulation of oxi-dative stress by methylation-controlled J protein controls macro-phage responses to inflammatory insults 显示文摘 | Navasa N Martin I Iglesias-Pedraz JM | 2015 | J Infect Dis2015，211，1： | 1 |
| 16 | Incidence and predictive factors of first episode of spontaneons bacterial peritonitis in cirrhosis with ascites:relevance of aseitie fluid protein concentration显示文摘 | Llach J Rimola A Navasa M | 1992 | Hepatology1992，16，： | 1 |
| 17 | Bacterial translocation of enteric organisms in patients with cirrhosis 显示文摘 | Cirera I Bauer TM Navasa M | 2001 | J Hepatol2001，34，： | 1 |
| 18 | Treatment of HCV infection in patients with advanced cirrhosis显示文摘 | Forns X Navasa M Rodes J | 2004 | Hepatology2004，40，2： | 1 |
| 19 | Renal impairment after spontaneous bacterial peritonitis in cirrhosis:incidence,clinical course,predictive factors and prognosis显示文摘 | Follo A Llovet JM Navasa M | 1994 | Hepatology1994，20，： | 1 |
| 20 | Acute cellular rejection in liver transplant recipients under cyclosporine immunosuppression:predictive factors of response to antirejection therapy显示文摘 | Andreu H Rimola A Bruguera M Navasa M Cirera I Grande L | 2002 | Transplantation2002，73，： | 1 |
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