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| 1 | Integrative genome-wide analysis reveals HLP1, a novel RNA-binding protein, regulates plant flowering by targeting alternative polyadenylation显示文摘 | Yong Zhang Lianfeng Gu Yifeng Hou Lulu Wang Xian Deng Runlai Hang Dong Chen Xiansheng Zhang Yi Zhang Chunyan Liu Xiaofeng Cao | 2015 | Cell Research2015，25，7： | 11 |
| 2 | Characteristics analysis on high density spatial sampling seismic data显示文摘中国的大陆人免职盆被复杂地质的结构和各种各样的水库岩性学描绘。因此,高精确探索方法被需要。高密度空间采样是一种新技术增加地震探索的精确性。我们简短讨论点来源和接收装置技术,分析高密度在 situ 方法的空间采样,介绍吉季斯· J · O 介绍的对称的采样原则。Vermeer,并且讨论高密度从波浪地连续性的观点的空间采样技术。我们强调高密度的分析空间采样特征,包括高密度,首先,裂缝为近的表面结构的调查有利,改善静态的修正精确,在到增加的短偏移量的稠密的接收装置间距的使用在浅深度的有效范围,和思考成像的精确性。协调噪音不是 aliased 和噪音分析精确,抑制作为结果增加。空间采样提高的高密度各种各样的数学变换的波浪地连续性和精确性,它受益飘动地分离。最后,我们指出空间采样技术是的高密度的困难的部分处理的数据。更多的研究需要在分析并且处理地震数据的巨大的数量的方法上被做。 | Cai Xiling Liu Xuewei Deng Chunyan Lv Yingme | 2006 | Applied Geophysics2006，3，1： | 11 |
| 3 | A Novel Approach to Automatic Security Protocol Analysis Based on Authentication Event Logic显示文摘Since security protocols form the cornerstones of modern secure networked systems, it is important to develop informative, accurate, and deployable approach for finding errors and proving that protocols meet their security requirements. We propose a novel approach to check security properties of cryptographic protocols using authentication event logic. Compared with logic of algorithm knowledge, authentication event logic guarantees that any well-typed protocol is robustly safe under attack while reasoning only about the actions of honest principals in the protocol. It puts no bound on the size of the principal and requires no state space enumeration and it is decidable. The types for protocol data provide some intuitive explanation of how the protocol works. Our approach has led us to the independent rediscovery of flaws in existing protocols and to the design of improved protocols. | XIAO Meihua MA Chenglin DENG Chunyan ZHU Ke | 2015 | Chinese Journal of Electronics2015，24，1： | 10 |
| 4 | Epigenetic regulation and epigenomic landscape in rice显示文摘Epigenetic regulation has been implicated in the control of complex agronomic traits in rice(Oryza sativa),a staple food crop and model monocot plant. Recent advances in high-throughput sequencing and the moderately complex genome of rice have made it possible to study epigenetic regulation in rice on a genome-wide scale. This review discusses recent advances in our understanding of epigenetic regulation in rice, with an emphasis on the roles of key epigenetic regulators, the epigenomic landscape, epigenetic variation, transposon repression, and plant development. | Xian Deng Xianwei Song Liya Wei Chunyan Liu Xiaofeng Cao | 2016 | National Science Review2016，3，3： | 8 |
| 5 | A Multicenter Study of Viral Aetiology of Community-Acquired Pneumonia in Hospitalized Children in Chinese Mainland显示文摘Community-acquired pneumonia(CAP) is one of the leading causes of morbidity and mortality in children worldwide.In this study,we aimed to describe the aetiology of viral infection of pediatric CAP in Chinese mainland.During November2014 to June 2016,the prospective study was conducted in 13 hospitals.The hospitalized children under 18 years old who met the criteria for CAP were enrolled.The throat swabs or nasopharyngeal aspirates(NPAs) were collected which were then screened 18 respiratory viruses using multiplex PCR assay.Viral pathogens were present in 56.6%(1539/2721) of the enrolled cases,with the detection rate of single virus in 39.8% of the cases and multiple viruses in 16.8% of the cases.The most frequently detected virus was respiratory syncytial virus(RSV)(15.2%,414/2721).The highest detection rate of virus was in <6-month-age group(70.7%,292/413).RSV,human metapneumovirus(HMPV),human parainfluenza viruses(HPIVs) and influenza B virus(Flu B) showed the similar prevalence patterns both in north and south China,but HPIVs,Flu A,human bocavirus(HBoV),human adenovirus(HAdV) and human coronaviruses(HCoVs) showed the distinct circulating patterns in north and south China.Human enterovirus/human rhinovirus(HEV/HRV)(27.6%,27/98),HBoV(18.4%,18/98),RSV(16.3%,16/98) and HMPV(14.3%,14/98) were the most commonly detected viruses in severe pneumonia cases with single virus infection.In conclusion,viral pathogens are frequently detected in pediatric CAP cases and may therefore play a vital role in the aetiology of CAP.RSV was the most important virus in hospitalized children with CAP in Chinese mainland. | Yun Zhu Baoping Xu Changchong Li Zhimin Chen Ling Cao Zhou Fu Yunxiao Shang Aihuan Chen Li Deng Yixiao Bao Yun Sun Limin Ning Shuilian Yu Fang Gu Chunyan Liu Ju Yin Adong Shen Zhengde Xie Kunling Shen | 2021 | Virologica Sinica2021，36，6： | 7 |
| 6 | Effects of the Fhb1 gene on Fusarium head blight resistance and agronomic traits of winter wheat显示文摘The gene Fhb1 has been used in many countries to improve wheat Fusarium head blight(FHB) resistance. To make better use of this gene in the Yellow-Huai River Valleys Winter Wheat Zone(YHWZ), the most important wheat-producing region of China, it is desirable to elucidate its effects on FHB resistance and agronomic traits in different genetic backgrounds. Based on a diagnostic marker for Fhb1, six BC2 populations were developed by crossing dwarf-male-sterile(DMS)-Zhoumai 16 to three Fhb1 donors(Ningmai 9, Ningmai 13, and Jianyang 84) and backcrossing to Zhoumai 16 and Zhoumai16’s derivative cultivars(Lunxuan 136 and Lunxuan 13) using marker-assisted backcross breeding. The progenies were assessed for FHB resistance and major agronomic traits.The Fhb1 alleles were identified using the gene-specific molecular marker. The plants with the Fhb1-resistant genotype(Fhb1-R) in these populations showed significantly fewer infected spikelets than those with the Fhb1-susceptible genotype(Fhb1-S). When Lunxuan 136 was used as the recurrent parent, Fhb1-R plants showed significantly fewer infected spikelets per spike than Fhb1-R plants produced using Lunxuan 13 as the recurrent parent, indicating that the genetic backgrounds of Fhb1 influence the expression of FHB resistance. Fhb1-R plants from the DMS-Zhoumai 16/Ningmai 9//Zhoumai 16/3/Lunxuan 136 population showed the highest FHB resistance among the six populations and a significantly higher level of FHB resistance than the moderately susceptible control Huaimai 20. No significant phenotypic differences between Fhb1-R and Fhb1-S plants were observed for the eight agronomic traits investigated. These results suggest that it is feasible to improve FHB resistance of winter wheat withoutreducing yield potential by introgressing Fhb1 resistance allele into FHB-susceptible cultivars in the YHWZ. | Teng Li Hongjun Zhang Yiwen Huang Zhenqi Su Yun Deng Hongwei Liu Chunyan Mai Guangjun Yu Huili Li Liqiang Yu Tongquan Zhu Li Yang Hongjie Li Yang Zhou | 2019 | The Crop Journal2019，7，6： | 6 |
| 7 | IL-17A-dependent gut microbiota is essential for regulating diet-induced disorders in mice显示文摘The gut microbiota plays a key role in obesity and related metabolic disorders, and multiple factors including diet, host genotype, and age regulate it. Many studies have examined the contribution of extrinsic factors to the regulation of the gut microbiota, but the importance of the host genetic constitution cannot be ignored. Interleukin 17A(IL-17A), a pro-inflammatory cytokine, is important in the defense against infection and diseases. Here, we investigated the association among IL-17, a high-fat diet(HFD), and the gut microbiota. Mice deficient in IL-17A were resistant to diet-induced obesity and related diseases. Compared with the Ⅱ-17^(-/-)mice, wild-type(WT) mice challenged with HFD showed obvious weight fluctuations, such as those seen in type 2 diabetes, and hematological changes similar to those associated with metabolic syndrome. However, housing WT mice and Ⅱ-17a^(-/-)mice together significantly alleviated these symptoms in the WT mice. A metagenomic analysis of the mouse feces indicated that the microbial community compositions of these two groups differed before HFD feeding. The HFD mediated shifts in the gut microbial compositions, which were associated with the mouse phenotypes.We also identified potentially beneficial and harmful species present during this period, and drew networks of the most abundant species. A functional analysis indicated pathway changes in the WT and Ⅱ-17a^(-/-)mice when fed the HFD. Collectively, these data underscore the importance of the host factor IL-17 A in shaping and regulating the gut microbiota, which conversely, influences the host health. | Yujing Bi Chunxiao Li Lin Liu Jiyuan Zhou Zhengchao Li Huimin Deng Chunyan Wu Yanping Han Yajun Song Yafang Tan Xiaoyi Wang Zongmin Du Yujun Cui Yanfeng Yan Fachao Zhi Guangwei Liu Nan Qin Heping Zhang Ruifu Yang | 2017 | Science Bulletin2017，62，15： | 5 |
| 8 | Stability control of steer by wire system based on μ synthesis robust control显示文摘The uncertainty influences may result in performance deterioration and instability to the steer by wire(SBW) system. Thus, it must make the control system keep robust stability from uncertainty, and have good robustness. In order to effectively restrain the interference and improve steering stability, this paper presents a μ synthesis robust controller based on SBW system, which considers the effect of model uncertainty and external disturbance on the system dynamics. Taking the ideal yaw rate tracking, interference suppression and excellent robustness as the control objectives, the μ synthesis robust controller is designed using linear fractional transformation theory to deal with the uncertainty. Then, it is testified through time domain and robustness simulation analysis. Simulation results show that the proposed controller can not only ensure robustness and robust stability of the system quite well, but improve handling stability of the vehicle effectively. The results of this study provide certain theoretical basis for the research and application of SBW system. | WANG ChunYan DENG Ke ZHAO WanZhong ZHOU Guan ZHOU Dong | 2017 | Science China(Technological Sciences)2017，60，1： | 5 |
| 9 | The direct electrochemistry of glucose oxidase based on the synergic effect of amino acid ionic liquid and carbon nanotubes显示文摘Amino acid ionic liquids(AAILs) have attracted much attention due to their special chemical and physical properties,especially their outstanding biocompatibility and truly green aspect.In this work,a novel electrochemical biosensing platform based on AAILs/carbon nanotubes(CNTs) composite was fabricated.AAILs were used as a novel solvent for glucose oxidase(GOD) and the GOD-AAILs/CNTs/GC electrode was conveniently prepared by immersing the carbon nanotubes(CNTs) modified glassy carbon(GC) electrode into AAILs containing GOD.The direct electrochemistry of GOD on the GOD-AAILs/CNTs/GC electrode has been investigated and a pair of reversible peaks was obtained by cyclic voltammetry.The immobilized glucose oxidase could retain bioactivity and catalyze the reduction of dissolved oxygen.Due to the synergic effect of AAILs and CNTs,the GOD-AAILs/CNTs/GC electrode shows excellent electrocatalytic activity towards glucose with a linear range from 0.05 to 0.8 mM and a detection limit of 5.5 μM(S/N = 3).Furthermore,the biosensor exhibits good stability and ability to exclude the interference of commonly coexisting uric and ascorbic acid.Therefore,AAILs/CNTs composite can be a good candidate biocompatible material for the direct electrochemistry of the redox-active enzyme and the construction of third-generation enzyme sensors. | WANG MengDong DENG ChunYan NIE Zhou XU XiaHong YAO ShouZhuo | 2009 | Science China Chemistry2009，52，11： | 4 |
| 10 | Image retrieval based on multi-concept detector and semantic correlation显示文摘With the rapid development of future network, there has been an explosive growth in multimedia data such as web images. Hence, an efficient image retrieval engine is necessary. Previous studies concentrate on the single concept image retrieval, which has limited practical usability. In practice, users always employ an Internet image retrieval system with multi-concept queries, but, the related existing approaches are often ineffective because the only combination of single-concept query techniques is adopted. At present semantic concept based multi-concept image retrieval is becoming an urgent issue to be solved. In this paper, a novel Multi-Concept image Retrieval Model(MCRM) based on the multi-concept detector is proposed, which takes a multi-concept as a whole and directly learns each multi-concept from the rearranged multi-concept training set. After the corresponding retrieval algorithm is presented, and the log-likelihood function of predictions is maximized by the gradient descent approach. Besides, semantic correlations among single-concepts and multiconcepts are employed to improve the retrieval performance, in which the semantic correlation probability is estimated with three correlation measures, and the visual evidence is expressed by Bayes theorem, estimated by Support Vector Machine(SVM). Experimental results on Corel and IAPR data sets show that the approach outperforms the state-of-the-arts. Furthermore, the model is beneficial for multi-concept retrieval and difficult retrieval with few relevant images. | XU HaiJiao HUANG ChangQin PAN Peng ZHAO GanSen XU ChunYan LU YanSheng CHEN Deng WU JiYi | 2015 | Science China Chemistry2015，58，12： | 3 |
| 11 | Robust control for active suspension system under steering condition显示文摘To minimize the auto body's posture change caused by steering and uneven road, and improve the vehicle's riding comfort and handling stability, this paper presents an H∞ robust controller of the active suspension system, which considers the effects of different steering conditions on its dynamic performance. The vehicle's vibration in the yaw, roll, pitch and vertical direction and the suspension's dynamic deflection in the steering process are taken into account for the designed H∞ robust controller, and it introduces the frequency weight function to improve the riding comfort in the specific sensitive frequency bands to human body. The proposed robust controller is testified through simulation and steering wheel angle step test. The results show that the active suspension with the designed robust controller can enhance the anti-roll capability of the vehicle, inhibit the changes of the body, and improve the riding comfort of the vehicle under steering condition. The results of this study can provide certain theoretical basis for the research and application of active suspension system. | WANG ChunYan DENG Ke ZHAO WanZhong ZHOU Guan LI XueSong | 2017 | Science China(Technological Sciences)2017，60，2： | 3 |
| 12 | BUB1B and circBUB1B_544aa aggravate multiple myeloma malignancy through evoking chromosomal instability显示文摘Multiple myeloma(MM)is an incurable plasma cell malignancy in the bone marrow characterized by chromosome instability(CIN),which contributes to the acquisition of heterogeneity,along with MM progression,drug resistance,and relapse.In this study,we elucidated that the expression of BUB1B increased strikingly in MM patients and was closely correlated with poor outcomes.Overexpression of BUB1B facilitated cellular proliferation and induced drug resistance in vitro and in vivo,while genetic targeting BUB1B abrogated this effect.Mechanistic studies unveiled that enforced expression of BUB1B evoked CIN resulting in MM poor outcomes mainly through phosphorylating CEP170.Interestingly,we discovered the existence of circBUB1B_544aa containing the kinase catalytic center of BUB1B,which was translated by a circular RNA of BUB1B.The circBUB1B_544aa elevated in MM peripheral blood samples was closely associated with MM poor outcomes and played a synergistic effect with BUB1B on evoking CIN.In addition,MM cells could secrete circBUB1B_544aa and interfere the MM microenvironmental cells in the same manner as BUB1B full-length protein.Intriguingly,BUB1B siRNA,targeting the kinase catalytic center of both BUB1B and circBUB1B_544aa,significantly inhibited MM malignancy in vitro and in vivo.Collectively,BUB1B and circBUB1B_544aa are promising prognostic and therapeutic targets of MM. | Xiaozhu Tang Mengjie guo Pinggang Ding Zhendong Deng Mengying Ke Yuxia Yuan Yanyan Zhou Zigen Lin Muxi Li Chunyan Gu Xiaosong Gu Ye Yang | 2021 | Signal Transduction and Targeted Therapy2021，6，11： | 2 |
| 13 | Implementation method of Oil and Gas Geologic Information System with ArcGIS Engine显示文摘ComGIS is the mainstream of developing GIS currently.Developing Geographic Information System with the technology of components can reduce the difficulties of developing,improving the developing efficiency and enhancing the flexibility and opening of system.ArcObjects(AO) is based on the technology of COM,and ArcGIS Engine(AE) is a set of embedded AO which can extend to various platforms.Compared with AO,ArcGIS Engine can shorten the period of developing and improve the efficiency greatly.Having introduced the techniques of ArcObjects and ArcGIS Engine,we offer the method of developing GIS with Visual Basic and ArcGIS Engine with Oil and Gas Geologic Information System. | Chunyan DENG Yunliang YU Shixiang LIU Ruiqing QIE Zhiguo ZHOU | 2007 | Global Geology2007，10，1： | 2 |
| 14 | Sensitive and specific HBV genomic DNA detection using RCA-based QCM biosensor显示文摘 | Chunyan Yao Yang Xiang Kun Deng Han Xia Weiling Fu | 2013 | Sensors & Actuators: B Chemical2013，，： | 1 |
| 15 | Assembly of layer-by-layer films of superoxide dismutase and gold nanorods:A third generation biosensor for superoxide anion显示文摘Based on the layer-by-layer self-assembly of positively charged cetyltrimethylammonium bromide (CTAB) wrapped gold na- norods (AuNRs) and negatively charged superoxide dismutase (SOD) from their aqueous solutions on cysteine modified gold electrode (Cys/Au), a third generation electrochemical biosensor ((SOD/AuNRs)2/Cys/Au) for superoxide anion (O2·-) was developed. The two layers assembly of SOD/AuNRs can significantly enhance the direct electron transfer between SOD and the electrode. The functional enzymatic activities of the SOD offer an electrochemical approach to the determination of O2·-. In the reductive regions, the proposed sensor exhibits excellent analytical performances, such as wide linear range (200 nM to 0.2 mM O2·-), low detection limit (100 nM O2·-), high sensitivity (22.11 nA cm-2 μM-1), short response time (less than 5 s), good stability and reproducibility, while no obvious interferences are caused by commonly met interfering species including hydrogen peroxide (H2O2), uric acid (UA) and ascorbic acid (AA). | WANG MengDong HAN YiTao LIU XingXing NIE Zhou DENG ChunYan GUO ManLi YAO ShouZhuo | 2011 | Science China Chemistry2011，54，8： | 1 |
| 16 | Study on the effect of EDTA on the photocatalytic reduction of mercury onto nanoerystalline titania using quartz crystal microbalanee and differential pulse voltammetry 显示文摘 | Zhou Jianhong Deng Chunyan Si Shihui | 2011 | Eleetroehimiea Acta2011，56，5： | 1 |
| 17 | Long-term outcomes of intensity-modulated radiotherapy for 868 patients with nasopharyngeal carcinoma: An analysis of survival and treatment toxicities显示文摘 | Xueming Sun Shengfa Su Chunyan Chen Fei Han Chong Zhao Weiwei Xiao Xiaowu Deng Shaomin Huang Chengguang Lin Taixiang Lu | 2013 | Radiotherapy and Oncology2013，，： | 1 |
| 18 | Deterministic secure quantum communication without maximally entangled states显示文摘 | Li Xihan Deng Fuguo Li Chunyan | 2006 | Journal of the Korean Physical Society2006，49，： | 1 |
| 19 | Quantum state sharing of an arbitrary two-qubit state with two-photon entanglements and Bell- state measurements显示文摘 | Deng Fugue Li Xihan Li Chunyan | 2006 | European Physical Journal D2006，39，3： | 1 |
| 20 | Multiparty quantum-state sharing of an arbitrary two-particle state with Einstein-Podolsky-Rosen Pairs显示文摘 | Deng Fugue Li Xihan Li Chunyan | 2005 | Physical Review A2005，72，04： | 1 |
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