|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 2018年美国糖尿病学会和欧洲糖尿病研究协会关于2型糖尿病高血糖管理的共识显示文摘美国糖尿病学会(ADA)和欧洲糖尿病研究协会(EASD)近期组织专家对2012—2015年间发表的关于成年2型糖尿病的管理共识进行了更新。专家组系统评价了2014年至今发表的文献,对高血糖的管理提出了新的共识。新共识包括更加强调2型糖尿病患者的生活方式管理、自我管理教育和支持。共识指出对于2型糖尿病伴肥胖者建议通过生活方式干预、药物和手术进行减重。 | Davies MJ D'Alessio DA Fradkin J 姜莹莹(编译) | 2019 | 中华预防医学杂志2019，53，2： | 19 |
| 2 | Quantitative monitoring of gene expression patterns with a complementary DNA microarray显示文摘 | Schena M Shalon D Davis RW | | 0，，： | 16 |
| 3 | Differential regulation of protein synthesis in skeletal muscle and liver of neonatal pigs by leucine through an mTORC1-dependent pathway显示文摘Neonatal growth is characterized by a high protein synthesis rate that is largely due to an enhanced sensitivity to the postprandial rise in insulin and amino acids, especially leucine. The mechanism of leucine's action in vivo is not well understood. In this study, we investigated the effect of leucine infusion on protein synthesis in skeletal muscle and liver of neonatal pigs. To evaluate the mode of action of leucine, we used rapamycin, an inhibitor of mammalian target of rapamycin (mTOR) complex-1 (mTORC1). Overnight-fasted 7-day-old piglets were treated with rapamycin for 1 hour and then infused with leucine (400 μmol·kg -1 ·h -1 ) for 1 hour. Leucine infusion increased the rate of protein synthesis, and ribosomal protein S6 kinase 1 (S6K1) and eukaryotic initiation factor (eIF) 4E-binding protein-1 (4E-BP1) phosphorylation in gastrocnemius and masseter muscles (P < 0.05), but not in the liver. The leucine-induced stimulation of protein synthesis and S6K1 and 4E-BP1 phosphorylation were completely blocked by rapamycin, suggesting that leucine action is by an mTORC1-dependent mechanism. Neither leucine nor rapamycin had any effect on the activation of the upstream mTORC1 regulators, AMP-activated protein kinase and protein kinase B, in skeletal muscle or liver. The activation of eIF2a and elongation factor 2 was not affected by leucine or rapamycin, indicating that these two pathways are not limiting steps of leucine-induced protein synthesis. These results suggest that leucine stimulates muscle protein synthesis in neonatal pigs by inducing the activation of mTORC1 and its downstream pathway leading to mRNA translation. | Agus Suryawan Hanh V Nguyen Rosemarie D Almonaci Teresa A Davis | 2012 | Journal of Animal Science and Biotechnology2012，3，1： | 9 |
| 4 | Definition and classification of cancer cachexia: an international consensus显示文摘 | Kenneth Fearon Florian Strasser Stefan D Anker Ingvar Bosaeus Eduardo Bruera Robin L Fainsinger Aminah Jatoi Charles Loprinzi Neil MacDonald Giovanni Mantovani Mellar Davis Maurizio Muscaritoli Faith Ottery Lukas Radbruch Paula Ravasco Declan Walsh Andrew | 2011 | Lancet Oncology2011，，5： | 8 |
| 5 | Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘 | W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van | 1997 | Cell1997，，2： | 6 |
| 6 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010，，9742： | 3 |
| 7 | Amino acids with in hypervariable region of avian coronavirus IBV (Massachusetts serotype) spike glycoprotein are associated with neutraiizan on epimpes显示文摘 | Cavanagh D Davis P L Mockett A P | 1998 | Virus Research1998，11，： | 2 |
| 8 | Biomarkers for diet and cancer prevention research:potentials and challenges显示文摘当癌症发生被投射增加十年,对有效预防策略有需要。幸好,证据继续到改变饮食的习惯是为减少癌症风险并且为修改肿瘤的生物行为的一条有效、成本效率的途径的山。预兆,验证并且敏感简历标记,包括可靠地评估“吸入”或暴露到特定的食物或简历的那些活跃部件,估计被连接到癌症的至少一特定的生物“效果”,并且有效地作为滋养营养素的相互作用和遗传的功能预言单个“危险性”,对评估基本将从饮食的 interventions.These 简历标记有益于大多数的人,一定容易地温和,容易并且可靠地 assayed ,并且涉及 cancer.Theresponse 到食物的一个关键过程( es )预兆被简历的有效集中决定不仅到达目标织物的活跃食物部件,而且由目标 requiringmodification.Thus 的数量,对食物和他们的部件的这阀值回答将从对理解个性化的回答是更大的知识 ofnutrigenomics , proteomics 和 metabolomics 关键的单个 toindividual.The 变化。 | Cindy D DAVIS John A MILNER | 2007 | Acta Pharmacologica Sinica2007，28，9： | 2 |
| 9 | 澳洲淡水龙虾(Cherax quadricarinatus)商业饲料中鸡肉粉替代鱼粉研究显示文摘水产动物红螯螯虾(Cherax quadricarinatus),俗称澳洲淡水龙虾,在热带和亚热带区域养殖发展十分迅速。由于饲料工业处于初级发展期,红螯螯虾营养需求与各种原料消化吸收率数据极其有限,生产饲料一般并未按照螯虾的特殊要求来单独设计配方。考虑到近期鱼粉价格上涨,使用类似鸡肉粉等替代蛋白源显得更为经济。本研究评价螯虾幼虾投喂使用鸡肉粉替代鱼粉的商业饲料生长效果。红螯螯虾幼虾(0.45±0.01) g暂养在户外圆池(容积24 600 L),密度为12.5尾/m2。养殖池水源为水库抽提,养殖期间保持流水。小龙虾投喂6种饲料,蛋白为26%,粗脂肪为7%,每个处理4个重复,在同等环境条件下生长良好。基础饲料中的鱼粉按比例被鸡肉粉替代,鱼粉含量递减为15%、12%、9%、6%、3%和0,而鸡肉粉含量递增为7.8%、10.5%、13.2%、15.8%、18.5%和21.2%,等氮等能饲料。经过56 d养殖试验,小龙虾所有试验组的存活率大于83%,增长11.3 g以上,处理组间没有显著差异。基于以上试验结果,可以得出结论,鸡肉粉适合作为小龙虾饲料中鱼粉的替代物。 | 刘训华 何志刚 Saoud,I P Rodgers,L J Davis,D A | 2019 | 饲料与畜牧2019，0，6： | 2 |
| 10 | Fiber grating sensors显示文摘 | Kersey A D Davis M A | 1997 | Journal of Lightwave Technology1997，15，8： | 2 |
| 11 | Vascular-specific growth factors and blood vessel formation显示文摘 | Yancopoulos G D Davis S Gale NW | | 0，，： | 2 |
| 12 | A machine program for theorem proving显示文摘 | M Davis G Logemann D Loveland | 1962 | Communications of the ACM1962，5，： | 2 |
| 13 | Fiber grating sensors显示文摘 | Kersey A D Davis M A Patrick H J | | 0，，： | 2 |
| 14 | Compact distributed RLC interconnect models-Part II: coupled line transient expressions and peak crosstalk in multilevel networks显示文摘 | Davis J A Meindl J D | 2000 | IEEE Trans Elec Dev2000，47，11： | 2 |
| 15 | Effective interventions for lifestyle change after myocardial infarction or coronary artery revascularization显示文摘 | COBB S L BROWN D J DAVIS L L | 2006 | J Am Acad Nurs Pract2006，18，1： | 1 |
| 16 | FT-IR and FT-raman spectral investigations of anatolian attapulgite and its interaction with 4,4'-bipyridyi显示文摘 | S Akyuz T Akyuz J E D Davies | 1995 | Journal of Molecular Structure1995，349，： | 1 |
| 17 | Triazoles as plant growth regulators and stress protectants 显示文摘 | FLETCHER R A GILLEY A DAVIS T D | 2000 | Horticulture Reviews2000，24，： | 1 |
| 18 | Undersea gliders for 6cean research 显示文摘 | Rudnick L Davis R Eriksen D | 2004 | Marine Tech Soc2004，38，2： | 1 |
| 19 | Perceived usefulness, perceived ease of use, and user acceptance of information technology 显示文摘 | Davis F D | 1989 | MIS Quarterly1989，13，3： | 1 |
| 20 | Calibration of near infrared reflectance spectroscopy to estimate nitrogen concentration in potato tissues显示文摘 | YOUNG M W MACKRRON D K L DAVIES H V | 1997 | PotatoResearch1997，，40： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员