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| 1 | 美国急性病医院预防医院感染策略纲要(2014更新版)Ⅰ显示文摘今年本刊已经介绍过2014版的英国NHS医院预防医院感染循证指南,现在呈现在读者面前的是2014更新版《美国急性病医院预防医院感染策略纲要》。这两个指南都是基于循证医学证据更新的,各有特点。2014更新版《美国急性病医院预防医院感染策略纲要》包括导尿管相关尿路感染(CAUTI)预防策略、艰难梭菌感染(CDI)预防策略、预防手术部位感染的策略、中心静脉导管相关血流感染(CLABSI)预防策略、耐甲氧西林金黄色葡萄球菌(MRSA)预防策略、呼吸机相关性肺炎(VAP)预防策略、手卫生预防医疗机构相关感染策略。这7个策略由美国医院流行病学会(SHEA)、感染病学会(IDSA)、医院协会(AHA)、感染控制与流行病专业人员协会(APIC),以及疾病预防控制中心(CDc)、医疗卫生改善研究院(IHI)、儿科感染病学会(PIDS)、重症医学学会(SCCM)、医院药学协会(SHM)、外科感染协会(SIS)等有关协会组织参加的联合委员会共同制定。 | 刘思娣 吴安华 Yokoe D S Anderson D J Berenholtz S M | 2014 | 中国感染控制杂志2014，13，11： | 17 |
| 2 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 3 | 美国急性病医院预防医院感染策略纲要(2014更新版)Ⅱ显示文摘预防手术部位感染(SSI)的策略
Ⅰ预防SSI的基本方法推荐给所有急性病医院。
1.依据基于循证医学证据的标准及指南,对患者预防性使用抗菌药物。(Ⅰ级质量证据)
2.除非毛发干扰手术操作,否则无需剃除手术部位的毛发;需要去除毛发时,也不使用剃须刀剃毛。(Ⅱ级质量证据)
3.接受心脏手术(Ⅰ级质量证据)和非心脏手术患者(Ⅱ级质量证据)术后要立刻控制血糖。4.围手术期维持体温在常温(≥35.5℃)。 | 刘思娣 吴安华 Yokoe D S Anderson D J Berenholtz S M | 2014 | 中国感染控制杂志2014，13，12： | 7 |
| 4 | 一种新型的高频半导体量子点单电子泵显示文摘除了直流负电压外,还在浅法刻蚀出的GaAs/AlGaAs量子线上的两个金属指形门上分别叠加两个相位相差π的正弦信号,从而对形成量子点的两个势垒作不等幅调制.在无源漏偏压的情况下,通过周期形成的量子点实现了单电子的搬运.由于新的半导体量子点单电子泵不是依赖库仑阻塞效应通过隧穿进行单电子输运,因此,该器件就不会受到固定隧穿时间引起的低工作频率限制.在1.7K温度下,频率达到3GHz仍然可以观测到量子化电流平台,对应的电流值达到0.5nA量级.这种新器件提供了实现高速度、高精度搬运单电子的另一种可能途径. | 李玲 Kaestner B Blumenthal M D Giblin S Janssen T J B M Pepper M Anderson D Jones G Ritchie D A 高洁 | 2008 | 物理学报2008，57，3： | 4 |
| 5 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010，，9742： | 3 |
| 6 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | 2012 (9859)2012，，9859： | 3 |
| 7 | Immunohistochemical analysis of the activation of NF-kappaB and expression of associated cytokines and adhesion molecules in human models of allergic inflammation显示文摘 | Wilson SJ Leone BA Anderson D | 1999 | J Pathol1999，189，： | 3 |
| 8 | Evaluation of C-reactive protein, an inflammatory marker, and infectious serology as risk factors for coronary artery disease and myocardial infarction显示文摘 | Jeffrey L Anderson John F Carlquist Joseph B Muhlestein Benjamin D Horne Sidney P Elmer | 1998 | Journal of the American College of Cardiology1998，，1： | 2 |
| 9 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 10 | Protein kinase B kinases that mediate phosphatidy linositol 3,4,5-trisphosphate-dependent activation of protein kinase B显示文摘 | Stephens L Anderson K Stokoe D | | 0，，： | 2 |
| 11 | 14-day triple, 5-day concomitant, and 10-day sequential therapies for Helicobacter pylori infection in seven Latin American sites: a randomised trial显示文摘 | E Robert Greenberg Garnet L Anderson Douglas R Morgan Javier Torres William D Chey Luis Eduardo Bravo Ricardo L Dominguez Catterina Ferreccio Rolando Herrero Eduardo C Lazcano-Ponce María Mercedes Meza-Montenegro Rodolfo Pe?a Edgar M Pe?a Eduardo Salazar- | 2011 | The Lancet2011，，9790： | 2 |
| 12 | Expression of a novel high-molecular-weight glutenin subunit gene in transgenic wheat显示文摘 | Blechl A E Anderson O D | 1996 | Nat Biotechnol1996，14，： | 2 |
| 13 | Duration of protection against Aeromonas salmonicida in brook trout immunostimulated with glucan or chitosan by injection or immersion显示文摘 | Anderson D P Siwicki A K | 1994 | The Progressive Fish Culturist1994，56，： | 2 |
| 14 | Precision atomic gravimeter based on Bragg diffraction显示文摘 | P A Altin M T Johnsson V Negnevitsky G R Dennis R P Anderson J E Debs S S Szigeti K S Hardman S Bennetts G D McDonald L D Turner J D Close N P Robins | 2013 | New Journal of Physics2013，，2： | 2 |
| 15 | Bone grafting, implants, and plating options for anterior cervical fusions显示文摘 | D Greg Anderson Todd J Albert | 2002 | Orthopedic Clinics of North America2002，，2： | 2 |
| 16 | The effect various antioxidants and other modifying agents on oxygen-radical-generated DNA damage in human lymphocytes in the COMET assay显示文摘 | Anderson D Yu TW Pillips BT | 1994 | Matation Res1994，307，： | 2 |
| 17 | Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing显示文摘 | Tice RR Agurell E Anderson D | 2000 | Environmental and molecular mutagenesis2000，35，： | 2 |
| 18 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | The Lancet2012，，9859： | 2 |
| 19 | Modulation of β-lactam resistance in Staphylococcus aureus by catechins and gallates显示文摘 | Paul D Stapleton Saroj Shah James C Anderson Yukihiko Hara Jeremy M.T Hamilton-Miller Peter W Taylor | 2004 | International Journal of Antimicrobial Agents2004，，5： | 2 |
| 20 | Unfrozen water contents of submarine permafrost determined by nuclear magnetic resonance 显示文摘 | Tice A R Anderson D M Sterrett K F | 1981 | Engineering Geology1981，18，： | 2 |
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