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2360篇 您的检索式:作者名="Crooke"
    题名 作者 年代 出处 被引量
1基于业绩表现:系统设计复杂学习的十大步骤显示文摘复杂学习任务理论把人的业绩表现置于中心位置。这些理论首先对预期业绩表现加以分析,强调整体性业绩表现目标的重要性。具体来说,复杂技能要求把重复性技能(又称“常规性”技能,即不随情况而变化的技能)与非重复性技能(如以知识为基础的问题解决与推理,即是随情形而变化的技能)加以协调组合。因此,没有必要严格区分陈述性知识学习与程序性知识学习,因为两者都是复杂学习任务的有效组成部分。复杂学习任务理论明确以改进业绩表现为宗旨,对单纯的记忆和知识构建不感兴趣。相反,它们注重的是如何应用这些知识解决实际生活中所遇到问题的能力。Jeroen J.G.van Merriěnboer Marcel B.M.de Crook 程景利 2003远程教育杂志2003,21,6:10
2Role of myeloid-derived suppressor cells in autoimmune disease显示文摘Myeloid-derived suppressor cells(MDSCs) represent an important class of immunoregulatory cells that can be activated to suppress T cell functions. These MDSCs can inhibit T cell functions through cell surface interactions and the release of soluble mediators. MDSCs accumulate in the inflamed tissues and lymphoid organs of patients with autoimmune diseases. Much of our knowledge of MDSC function has come from studies involving cancer models, however many recent studies have helped to characterize MDSC involvement in autoimmune diseases. MDSCs are a heterogeneous group of immature myeloid cells with a number of different functions for the suppression of T cell responses. However, we have yet to fully understand their contributions to the development and regulation of autoimmune diseases. A number of studies have described beneficial functions of MDSCs during autoimmune diseases, and thus there appears to be a potential role for MDSCs in the treatment of these diseases. Nevertheless, many questions remain as to the activation, differentiation, and inhibitory functions of MDSCs. This review aims to summarize our current knowledge of MDSC subsets and suppressive functions in tissue-specific autoimmune disorders. We also describe the potential of MDSC-basedcell therapy for the treatment of autoimmune diseases and note some of hurdles facing the implementation of this therapy.Kristen R Crook Peng Liu 2014World Journal of Immunology2014,4,1:9
3INCREASING CREATIVITY AND INNOVATION IN ENGLISH LANGUAGE TEACHING IN CHINA显示文摘Creativity and innovation in English language teaching(ELT)are frequently discussed and debated. Recently the Ministry of Education(MOE)of China has urged the development of a system,which en- hances creative ability in students at all levels. Hawaii’s East-West Center in collaboration with the Ohana Foundation implemented an educational re- search activity designed to assess the current needs and best practices for English language teaching and learn- ing at the middle school level in China.The project focused on increasing creativity and innovation in English language education and used case studies of successful English language teaching/learning as the unit of analysis. Researchers from both China and the United States were involved with the analysis and made rec- ommendations for implementing innovative approach- es to English language instruction and on how to in- crease creativity in teacher training,curriculum de- velopment,and the use of appropriate technology.Larry E.Smith Graham Crookes Frank Tang 2000Chinese Journal of Applied Linguistics2000,23,3:8
4Trace element characteristics of graywackes and tectonic setting discrimination of sedimentary basins显示文摘Mukul R. Bhatia Keith A. W. Crook 1986Contributions to Mineralogy and Petrology1986,,2:5
5Experiences in Teaching World History in English显示文摘如何用英语开设世界历史课程?本文作者谈了他在教学中的体会: 1.要在这门概述性课程中体现历史唯物主义的观点,防止“欧洲中心论”。 2.中国学生习惯于依赖教师的讲课获取知识。因此,在教学的各个环节都要鼓励学生独立阅读与思考。 3.课堂讨论既可锻炼学生用英语表达思想,又可了解和纠正学生中一些不正确的想法,推动学习的深入。 4.目前学生选课过多,这难免影响他们独立、主动地学习,造成知识的浅薄。 5.用英语开设世界历史课程,促进了语言课和知识课的结合,显示了把单纯的外语学院办成综合性的文科外语大学的重要性。David Crook 1983外语教学与研究1983,15,3:3
6The Study of Nursing Care project: back to the future for contemporary nursing research?显示文摘Kylie M. Smith Patrick A. Crookes 2012Journal of Advanced Nursing2012,,11:2
7Analysis of somatostatin receptor subtype mRNA expression in human breast cancer显示文摘Evans AA Crook T Laws S 1997BrJ Cancer1997,75,:2
8System dynamic modelling to assess economic viability and risk trade-offs for ecological restoration in South Africa显示文摘D.J. Crookes J.N. Blignaut M.P. de Wit K.J. Esler D.C. Le Maitre S.J. Milton S.A. Mitchell J. Cloete P. de Abreu H. Fourie (nee Vlok) K. Gull D. Marx W. Mugido T. Ndhlovu M. Nowell M. Pauw A. Rebelo 2013Journal of Environmental Management2013,,:2
9Is Type II diabetes mellitus a disease of the innate immune system?显示文摘J. C. Pickup M. A. Crook 1998Diabetologia1998,,10:2
10An evaluation of risk factors for inadequate cytology in EUS-guided FNA of pancreatic tumors and lymph nodes显示文摘Patrick Cleveland Kanwar Rupinder S. Gill Susan G. Coe Timothy A. Woodward Massimo Raimondo Laith Jamil Seth A. Gross Michael G. Heckman Julia E. Crook Michael B. Wallace 2010Gastrointestinal Endoscopy2010,,7:2
11Variation in fibre diameter profile characteristics between wool staple in Merino sheep 显示文摘Brown D J Crook B J Purvis I W 2000Wool Technology and Sheep Breeding2000,,48:2
12Antisense Technology: An Emerging Platform for Cardiovascular Disease Therapeutics显示文摘Richard G. Lee Jeff Crosby Brenda F. Baker Mark J. Graham Rosanne M. Crooke 2013Journal of Cardiovascular Translational Research2013,,6:2
13Selectively permeable dendrimers as molecular gates显示文摘Gregory P Perez Richard M Crooks 2001Interface2001,10,:2
14Effective stress paths and yielding in soft clays below embankments显示文摘Flokes D J Crooks J H A 1985Canadian Geotechnical Journal1985,22,1:2
15The isothermal austenite-ferrite transformation in some deformed vanadium steels显示文摘M J Crooks A J Garratt-Reed J B Vander Sande W S Owen 1982Metallurgical Transactions A1982,,8:2
16Is type 2 diabetes mellitus a disease of the innate immune system显示文摘Pick JC Crook MA 1998Diahetologia1998,41,:1
17Characterization of the glucuronide conjugate of cotinine: A previously unidentified major metabolite of nicotine in smoker urine 显示文摘Caldwell W S Crooks P A Bhatti B S et ol 1992Chem Res Toxicol1992,5,:1
18Is type 2 diabetes mellitus a disease of the innate immune system显示文摘Pickup JC Crook MA 2000Diabetolog2000,41,10:1
19CD147 (EMMPRIN) and matrix metallopro- teinase-2 expression in uterine endometrioid adenocarcinoma 显示文摘Stewart C J Crook ML 2011Pathol Res Pract2011,207,1:1
20Potential roles of antisense technology in cancer chemotherapy显示文摘Crooke S T 2000Oncogene2000,19,66:1
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