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| 1 | Hypertension and renal disease显示文摘The relationship between chronic kidney disease(CKD)and hypertension remains enigmatic and a matter of considerable clinical and academic interest with evidence indicating that hypertension is both a cause and a consequence of kidney disease[1-2]. | Huang Chunfa Louis Stokes Cleveland Veteran Affairs Medical Center Division of Nephrology,Departments of Medicine,Case Western Reserve University and Rammelkamp Center for Research and Education,MetroHealth System Campus,Cleveland,Ohio 441061 | 2011 | 中华高血压杂志2011，19，12： | 23 |
| 2 | 人口普查净误差估计中的三系统估计量研究显示文摘本文针对作为当今人口普查质量评估领域主流方法的双系统估计量因受独立性不满足困扰而有偏估计总体人数的问题,明确提出了用三系统估计量替代双系统估计量的研究目标。三系统估计量指的是依据对同一时点上同一总体的人口普查、人口普查之后的质量评估调查和人口行政记录系统这三个不同途径获得的三份人口登记数据来估计总体人数所使用的估计量。为实现上述目标,采用实地调研、数理模型、抽样估计与实证分析相结合的研究方法,以及借鉴国际相关前沿研究成果的研究思路,研究了人口普查质量评估中三系统估计量的构建、三系统估计量应用操作等问题。通过理论与实证研究,得出如下结论:三系统估计量能够有效地摆脱双系统估计量的独立性约束从而解决估计量偏误的问题;将三系统估计量应用于人口普查质量评估,必须科学合理地解决三个人口登记系统定格在统一的标准时点、人口在三个登记系统等概率分层、用人口普查质量评估调查样本对三系统估计量再估计等实践方面的问题;基于Logistic回归模型的三系统估计量可以较好地实现人口等概率分层目标,但尚有较多的理论与实践问题有待研究解决,在这一问题上有着相当大的研究空间。建议我国在未来人口普查质量评估中应用三系统估计量。 | 胡桂华 Robert McCaa Lara Cleveland | 2017 | 统计研究2017，34，6： | 16 |
| 3 | BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules显示文摘Error-free mitosis depends on accurate chromosome attachment to spindle microtubules, powered congression of those chromosomes, their segregation in anaphase, and assembly of a spindle midzone at mitotic exit. The centromere-associated kinesin motor CENP-E, whose binding partner is BubR1, has been implicated in congression of misaligned chromosomes and the transition from lateral kinetochore-microtubule association to end-on capture. Although previously proposed to be a pseudokinase, here we report the structure of the kinase domain of Drosophila melanogaster BubR1, revealing its folding into a conformation predicted to be catalytically active. BubR1 is shown to be a bona fide kinase whose phosphorylation of CENP-E switches it from a laterally attached microtubule motor to a plus-end microtubule tip tracker. Computational modeling is used to identify bubristatin as a selective BubR1 kinase antagonist that targets the αN1 helix of N-terminal extension and αC helix of the BubR1 kinase domain. Inhibition of CENP-E phosphorylation is shown to prevent proper microtubule capture at kinetochores and, surprisingly, proper assembly of the central spindle at mitotic exit. Thus, BubR1-mediated CENP-E phosphorylation produces a temporal switch that enables transition from lateral to end-on microtubule capture and organization of microtubules into stable midzone arrays. | Yuejia Huang Lin Lin Xing Liu Sheng Ye Phil Y. Yao Wenwen Wang Fengrui Yang Xinjiao Gao Junying Li Yin Zhang Jiancun Zhang Zhihong Yang Xu Liu Zhenye Yang Jianye Zang Maikun Teng Zhiyong Wang Ke Ruan Xia Ding Lin Li Don W. Cleveland Rongguang Zhang Xuebiao Yao | 2019 | Cell Research2019，29，7： | 8 |
| 4 | Effect of Recql5 deficiency on the intestinal tumor susceptibility of Apc^(min) mice显示文摘AIM:To investigate whether Recql5,a DNA helicase that plays an important role in the maintenance of genome integrity,is a tumor suppressor in the gastrointestinal tract in mice.METHODS:We generated cohorts of both Recql5-proficient and Recql5-deficient Apcmin/+mice and compared the tumor susceptibility in their gastrointestinal tracts.RESULTS:Recql5 deficiency in Apcmin/+mice resulted in a significant increase in the tumor incidence in both the colon(P=0.0162)and the small intestine(P<0.01).These findings have provided the first genetic evidence for a tumor suppression role of Recql5 in the gastrointestinal tract of mice.Importantly,since mouse Recql5 and human RECQL5 are highly conserved,these findings also suggest that RECQL5 may be a tu-mor suppressor for human colon cancer.CONCLUSION:Recql5 has a tumor suppression role in the mouse gastrointestinal tract. | Yiduo Hu,Xincheng Lu,Guangbin Luo,Department of Genetics,Case Comprehensive Cancer Center and University Hospitals of Cleveland,Case Western Reserve University,Cleveland,OH 44106,United States Yiduo Hu,Department of Cancer Biology,Dana-Farber Cancer Institute,Boston,MA 02115,United States | 2010 | World Journal of Gastroenterology2010，16，12： | 6 |
| 5 | Composition Operators on a Banach Space of Analytic Functions | Cao Guangfu (Department of Mathematics,Sichuan University,Chengdu 610064,China)N.Elias (6611 Tauglewood Court 3B,Hammond,IN46323)P.Ghatage (Department of Mathematics,Cleveland State University,Cleveland,OH44115)Yu Dahai (Department of Mathematics,Sichuan University,Chengdu 610064,China) | 1998 | Acta Mathematica Sinica,English Series1998，14，2： | 4 |
| 6 | 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society显示文摘 | Craig T. January L. Samuel Wann Joseph S. Alpert Hugh Calkins Joaquin E. Cigarroa Joseph C. Cleveland Jamie B. Conti Patrick T. Ellinor Michael D. Ezekowitz Michael E. Field Katherine T. Murray Ralph L. Sacco William G. Stevenson Patrick J. Tchou Cynthia | 2014 | Circulation2014，，23： | 4 |
| 7 | C:N:P stoichiometry in soil: is there a “Redfield ratio” for the microbial biomass?显示文摘 | Cory C. Cleveland Daniel Liptzin | 2007 | Biogeochemistry2007，，3： | 4 |
| 8 | Nitrogen Cycles: Past, Present, and Future显示文摘 | J. N. Galloway F. J. Dentener D. G. Capone E. W. Boyer R. W. Howarth S. P. Seitzinger G. P. Asner C. C. Cleveland P. A. Green E. A. Holland D. M. Karl A. F. Michaels J. H. Porter A. R. Townsend C. J. V?osmarty | 2004 | Biogeochemistry2004，，2： | 4 |
| 9 | Widely predicting specific protein functions based on protein-protein interaction data and gene expression profile显示文摘GESTs (gene expression similarity and taxonomy similarity), a gene functional prediction approach previously proposed by us, is based on gene expression similarity and concept similarity of functional classes defined in Gene Ontology (GO). In this paper, we extend this method to protein-protein interac-tion data by introducing several methods to filter the neighbors in protein interaction networks for a protein of unknown function(s). Unlike other conventional methods, the proposed approach automati-cally selects the most appropriate functional classes as specific as possible during the learning proc-ess, and calls on genes annotated to nearby classes to support the predictions to some small-sized specific classes in GO. Based on the yeast protein-protein interaction information from MIPS and a dataset of gene expression profiles, we assess the performances of our approach for predicting protein functions to “biology process” by three measures particularly designed for functional classes organ-ized in GO. Results show that our method is powerful for widely predicting gene functions with very specific functional terms. Based on the GO database published in December 2004, we predict some proteins whose functions were unknown at that time, and some of the predictions have been confirmed by the new SGD annotation data published in April, 2006. | GAO Lei1, LI Xia1,2, GUO Zheng1,2, ZHU MingZhu1, LI YanHui1 & RAO ShaoQi1,3 1 Department of Bioinformatics, Harbin Medical University, Harbin 150086, China 2 School of Biology Science and Technology, Tongji University, Shanghai 200092, China 3 Departments of Molecular Cardiology and Cardiovascular Medicine, the Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleve-land, Ohio 44195, USA | 2007 | Science China(Life Sciences)2007，50，1： | 3 |
| 10 | Nitrogen Cycles: Past, Present, and Future显示文摘 | J. N. Galloway F. J. Dentener D. G. Capone E. W. Boyer R. W. Howarth S. P. Seitzinger G. P. Asner C. C. Cleveland P. A. Green E. A. Holland D. M. Karl A. F. Michaels J. H. Porter A. R. Townsend C. J. V?osmarty | 2004 | Biogeochemistry2004，，2： | 2 |
| 11 | 所谓'朱子的社仓'与当代道学社群和政府里的士大夫的关系显示文摘尽管建立社仓系统的功劳总是归于朱熹一人名下,但是本文强调建立社仓如何从诸儒的社交 往来,道学群体和官员合作中产生发展。我并不是想贬低朱熹的贡献,而只希望我们可以回溯到诸儒的群体 中去考察他们之间的交游与合作,而不仅仅局限于朱熹一人。也希望我们可以稍微增强我们对于朱熹的社会 与政治关系网的理解。 | 田浩(Hoyt Cleveland Tillman) 阎琨 | 2004 | 黄山学院学报2004，，4： | 2 |
| 12 | A randomized, controlled trial of oral sulfate solution plus polyethylene glycol as a bowel preparation for colonoscopy显示文摘 | Douglas K. Rex John McGowan Mark vB. Cleveland Jack A. Di Palma | 2014 | Gastrointestinal Endoscopy2014，，： | 2 |
| 13 | 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society显示文摘 | Craig T. January L. Samuel Wann Joseph S. Alpert Hugh Calkins Joaquin E. Cigarroa Joseph C. Cleveland Jamie B. Conti Patrick T. Ellinor Michael D. Ezekowitz Michael E. Field Katherine T. Murray Ralph L. Sacco William G. Stevenson Patrick J. Tchou Cynthia | 2014 | Circulation2014，，23： | 2 |
| 14 | An evaluation of risk factors for inadequate cytology in EUS-guided FNA of pancreatic tumors and lymph nodes显示文摘 | Patrick Cleveland Kanwar Rupinder S. Gill Susan G. Coe Timothy A. Woodward Massimo Raimondo Laith Jamil Seth A. Gross Michael G. Heckman Julia E. Crook Michael B. Wallace | 2010 | Gastrointestinal Endoscopy2010，，7： | 2 |
| 15 | A randomized, placebo-controlled, multicenter study of the safety and efficacy of a new polyethylene glycol laxative显示文摘 | Jack A DiPalma Peter H DeRidder Roy C Orlando Byron E Kolts Mark vB Cleveland | 2000 | The American Journal of Gastroenterology2000，，2： | 2 |
| 16 | Oral Sulfonylurea Hypoglycemic Agents Prevent Ischemic Preconditioning in Human Myocardium: Two Paradoxes Revisited显示文摘 | Joseph C. Jr Cleveland Daniel R. Meldrum Brian S. Cain Anirban Banerjee Alden H. Harken | 1997 | Circulation1997，，1： | 2 |
| 17 | Bacteriocins: safe natural antimierobials for food preservation显示文摘 | Cleveland J Montville T J Nes I F | 2001 | International Journal of Food Microbiology2001，71，1： | 1 |
| 18 | The benefits of combined anti-platelet treatment in carotid artery stenting显示文摘 | RANDALL MS CLEVELAND TJ | 2005 | Eur J Vasc Endovasc Surg2005，29，： | 1 |
| 19 | STL:A Seasonal-Trend Decomposition Procedure Based on Loess显示文摘 | Cleveland R B Cleveland W S Mcrae J E | 1990 | Journal of Official Statistics1990，6，1： | 1 |
| 20 | Automated pKa determination at low solute concentration by capillary electrophoresis 显示文摘 | Cleveland J J Benko M H Gluck S J | 1993 | Journal of Chromatography A1993，652，2： | 1 |
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