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| 1 | Relationship between the severity of hepatitis C virus-related liver disease and the presence of Helicobacter species in the liver: A prospective study显示文摘AIM: To determine the presence of Helicobacter species DNA in the liver of chronic hepatitis C (CHC) patients with and without cirrhosis as compared to controls, and to identify the bacterial species involved. METHODS: Seventy-nine consecutive patients (HBV and HIV negative) with a liver sample obtained after liver biopsy or hepatic resection were studied: 41 with CHC without cirrhosis, 12 with CHC and cirrhosis, and 26 controls (HCV negative). Polymerase chain reactions (PCRs) targeting Helicobacter 16S rDNA and species- specific were performed on DNA extracted from the liver. A gastric infection with H pylori was determined by serology and confirmed by 13C-urea breath test. RESULTS: Overall, Helicobacter 16S rDNA was found in 16 patients (20.2%). Although positive cases tended to be higher in CHC patients with cirrhosis (41.6%) than in those without cirrhosis (17.0%) or in controls (15.4%), the difference was not statistically significant (P =0.08). H pylori-like DNA was identified in 12 cases and H. pullorum DNA in 2, while 2 cases remained unidenti- fied. Gastric infection with H pylori was found in only 2 of these patients. CONCLUSION: Our results do not confirm the associ- ation of Helicobacter species DNA in the liver of CHC patients with advanced liver disease. The lack of correlation between positive H pylori serology and the presence of H pylori-like DNA in the liver may indicate the presence of a variant of this species. | Laurent Castéra Anne Pedeboscq Marcia Rocha Brigitte Le Bail Corinne Asencio Victor de Lédinghen Pierre-Henri Bernard Christophe Laurent Marie-Edith Lafon Maylis Capdepont Patrice Couzigou Paulette Bioulac-Sage Charles Balabaud FrancisMégraud Armelle Ménard | 2006 | World Journal of Gastroenterology2006，12，45： | 3 |
| 2 | 加工时间离散可控作业车间调度问题分解方法显示文摘给出了加工时间离散可控的作业车间调度问题(job-shop scheduling problem with discretely controllable processing times,JSP-DCPT)基于析取图的模型及其数学描述.提出一种三步分解方法,使得JSP-DCPT可以通过求解一个作业车间调度问题(job-shop scheduling problem,JSP)以及一系列离散时间-成本权衡问题得到解决.为简化分解方法,引入时间-成本相平面描述离散时间-成本权衡问题的权衡点,并详细阐释了一种基于极限模式的集合支配理论以确定用于消减JSP-DCPT分解所得离散时间-成本权衡问题的一个上界.随后提出一种基于极限模式的集合支配分解算法EMSDDA(extreme mode-based set dominant decomposition algorithm).基于JSP标准算例FT10构造了测试算例JSPDCPT_FT10,实验仿真验证了提出的理论及分解方法的有效性. | 牛刚刚 孙树栋 Lafon Pascal 杨宏安 | 2011 | 中国科学:技术科学2011，41，3： | 2 |
| 3 | A decomposition approach to job-shop scheduling problem with discretely controllable processing times显示文摘Job-shop scheduling problem with discretely controllable processing times (JSP-DCPT) is modeled based on the disjunctive graph, and the formulation of JSP-DCPT is presented. A three-step decomposition approach is proposed so that JSP-DCPT can be handled by solving a job-shop scheduling problem (JSP) and a series of discrete time-cost tradeoff problems. To simplify the decomposition approach, the time-cost phase plane is introduced to describe tradeoffs of the discrete time-cost tradeoff problem, and an extreme mode-based set dominant theory is elaborated so that an upper bound is determined to cut discrete time-cost tradeoff problems generated by using the proposed decomposition approach. An extreme mode-based set dominant decomposition algorithm (EMSDDA) is then proposed. Experimental simulations for instance JSPDCPT_FT10, which is designed based on a JSP benchmark FT10, demonstrate the effectiveness of the proposed theory and the decomposition approach. | NIU GangGang SUN ShuDong LAFON Pascal YANG HongAn | 2011 | Science China(Technological Sciences)2011，54，5： | 2 |
| 4 | Distribution of trace metals and Pb isotopes in bottom sediments of the Murucupi River,North Brazil显示文摘The Murucupi River belongs to the hydrographic network of the Para River estuary,at the southern portion of the Amazon River mouth,which consists of a fluvial-marine transitional zone under strong impact of both tidal and fluvial currents.The geochemical results obtained for bottom sediments from the Murucupi River,the Arrozal Channel,and the Para River indicate a natural variation of Pb,Cr,Cu,Zn,and Ni content among these water ways with no significant anthropogenic influence.According to the threshold effects level(TEL),the contents of trace metals do not offer risk to the local biota.By contrast,the differences in the Pb isotopic composition of sediments in the Murucupi River,the Arrozal Channel,and the Para River are significant.These isotopic signatures indicate an anthropogenic contribution of Pb in the Murucupi River originating from the domestic effluents of urban centers;industrial waste represented by red mud is not included.These results demonstrate that the Pb isotopic signature is a prospective indicator for future contamination of bottom sediments by trace metals and is useful for identifying contaminants among the possible anthropogenic sources. | Diomar Cavalcante Oliveira Jean Michel Lafon Marcelo de Oliveira Lima | 2016 | International Journal of Sediment Research2016，31，3： | 2 |
| 5 | Modafinil显示文摘 | Lafon L | 1990 | Drugs Fut1990，15，2： | 1 |
| 6 | Intraoperative three dimensional correction during in situ contouring surgery by using a numerical model显示文摘 | Lafon Y Steib JP Skal i W | | 0，，1976： | 1 |
| 7 | An evaluation of second generation tissue culture rabies vaccines for use in man: a fourvaccine comparative immunogenicity study using a pre-exposure vaccination schedule and an abbreviated 2-1-1 postexposure schedule 显示文摘 | Vodopija I Sureau P Lafon M | 1986 | Vaccine1986，4，4： | 1 |
| 8 | Immunobiology of lyssaviruses:the basis for immunoprotection显示文摘 | Lafon M | 1994 | Curr Top Microbiol Immund1994，187，： | 1 |
| 9 | An evaluation of sec- ondgeneration tissue culture rabies vaccines for use in man : a four- vaccine comparative immunogenicity study using a preexposure vaccination schedule and an abbreviated 2 - 1 - 1 postexposure schedule 显示文摘 | VODOPIJA I SUREAU P LAFON M | 1986 | Vaccine1986，4，4： | 1 |
| 10 | Diffusion maps, spectral clustering and the reaction coordinates of dynamical systems 显示文摘 | Nadler B Lafon S Coifman R R | 2006 | Applied and Computational Harmonic Analysis2006，21，1： | 1 |
| 11 | Diffusion maps and coarse-graining:a uni- fied framework for dimensionality reduction, graph partitio- ning, and data set parametefization 显示文摘 | Lafon S Lee A B | 2006 | IEEE Transactions on Pattern Analysis and Machine Intelligence2006，28，9： | 1 |
| 12 | Diffusion maps, reduction coordinates, and low dimensional representation of stochastic systems 显示文摘 | Coifman R R Kevrekidis I G Lafon S | 2008 | Muhiscale Model and Simulation2008，7，2： | 1 |
| 13 | An original approach based on data exchange between car manu- facturers and suppliers to estimate susceptibility threshold by numerical simulation at early design stage显示文摘 | Chahine I Bunlon X Lafon F | 2013 | IEEE Transactions on Electromagnetic Compatibility2013，55，2： | 1 |
| 14 | Endoscopic treatment of cholangiocarcinoma and carcinoma of the duodenal papilla by intraductal high intensity US: results of a pilot study显示文摘 | Prat F Lafon C De Lima DM | 2002 | Gas trointest Endosc2002，56，6： | 1 |
| 15 | Gel phantom for use in high-intensity focused ultrasound dosimetery显示文摘 | Lafon C Zderic V Noble ML | 2005 | Ultrasound Med Bio2005，31，10： | 1 |
| 16 | PDZ domain-mediated protein interactions: therapeutic targets in neurological disorders显示文摘 | KHAN Z LAFON M | 2014 | Curr Med Chem2014，21，23： | 1 |
| 17 | Lateralization of prefrontal activation during internal mental calculation:a functional magnetic resonance imaging study显示文摘 | Burbaud P Degreze P Lafon P | 1995 | J Neurophysiol1995，74，5： | 1 |
| 18 | Antivirai activity of monoclonal antibodies specific for the international proteins N and NS of rabies virus 显示文摘 | Lafon M Lafage M | 1987 | J Virul1987，68，： | 1 |
| 19 | Aerody- namics and acoustics of rectangular and swept rotor blade tips显示文摘 | PRIEUR J LAFON P CAPLOT M | 1989 | Journal of the American Helicopter So- ciety1989，34，1： | 1 |
| 20 | Intraoperative three dimen- sional correction during in situ contouring surgery by u- sing a numerical model显示文摘 | Lafon Y Steib JP Skalli W | 2010 | Spine(Phila Pa 1976)2010，35，45： | 1 |
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