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| 1 | 螺内酯与可乐定作为难治性高血压第4种治疗药物的比较:难治性高血压的最佳治疗随机研究显示文摘该研究旨在通过一个多中心随机试验对作为难治性高血压患者的第4种治疗药物的螺内酯与可乐定进行比较。采用药丸计数评估药物治疗依从性。难治性高血压患者(定义为包括1种利尿剂在内的3种药物治疗12周,诊室及动态血压监测血压仍未控制)随机给予螺内酯(12.5~50 mg/d)或可乐定(0.1~0.3mg,2次/d)继续治疗12周。 | Krieger EM Drager LF Giorgi DMA Pereira AC Barreto-Filho JAS Nogueira AR Mill JG Lotufo PA Amodeo C Batista MC Bodanese LC Carvalho ACC Castro I Chaves H Costa EAS Feitosa GS Franco RJS Fuchs FD Guimarāes AC Jardim PC Machado CA Magalhāes ME Mion D Jr Nascimento RM Nobre F Nóbrega AC Ribeiro ALP Rodrigues-Sobrinho CR Sanjuliani AF Teixeira MDCB Krieger JE ReHOT Investigators 赵狄 练桂丽 | 2018 | 中华高血压杂志2018，26，3： | 7 |
| 2 | Pseudomelanosis duodeni associated with chronic renal failure显示文摘Pseudomelanosis duodeni (PD) is a rare dark speckled appearance of the duodenum associated with gastrointestinal bleeding,hypertension,chronic heart failure,chronic renal failure and consumption of different drugs.We report four cases of PD associated with chronic renal failure admitted to the gastroenterology outpatient unit due to epigastric pain,nausea,melena and progressive reduction of hemoglobin index.Gastroduodenal endoscopy revealed erosions in the esophagus and stomach,with no active bleeding at the moment.In addition,the duodenal mucosa presented marked signs of melanosis;later confirmed by histopathological study.Even though PD is usually regarded as a benign condition,its pathogenesis and clinical significance is yet to be defined. | Marcia Henriques de Magalhes Costa Maria da Gloria Fernandes Pegado Cleber Vargas Maria Elizabeth C Castro Kalil Madi Tiago Nunes Cyrla Zaltman | 2012 | World Journal of Gastroenterology2012，18，12： | 2 |
| 3 | How to manage inflammatory bowel disease during the COVID-19 pandemic:A guide for the practicing clinician显示文摘Managing inflammatory bowel disease(IBD)during the coronavirus disease 2019(COVID-19)pandemic has been a challenge faced by clinicians and their patients,especially concerning whether to proceed with biologics and immunosuppressive agents in the background of a global outbreak of a highly contagious new coronavirus(severe acute respiratory syndrome coronavirus 2,SARS-CoV-2).The knowledge about the impact of this virus on patients with IBD,although it is still scarce,is rapidly evolving.In particular,concerns surrounding medications’impact for IBD on the risk of acquiring SARS-CoV-2 infection or developing COVID-19,and potentially exacerbate viral replication and the COVID-19 course,are a current thinking of both practicing clinicians and providers caring for patients with IBD.Managing patients with IBD infected with SARS-CoV-2 depends on both the clinical activity of the IBD and the occasional development and severity of COVID-19.In this review,we summarize the current data regarding gastrointestinal involvement by SARS-CoV-2 and pharmacologic and surgical management for IBD concerning this infection,and the COVID-19 impact on both the patient's psychological functioning and endoscopy services,and we concisely summarize the telemedicine roles during the COVID-19 pandemic. | Júlio Maria Fonseca Chebli Natália Sousa Freitas Queiroz Adérson Omar Mourão Cintra Damião Liliana Andrade Chebli Márcia Henriques de Magalhães Costa Rogério Serafim Parra | 2021 | World Journal of Gastroenterology2021，27，11： | 2 |
| 4 | Development of hepatorenal syndrome in bile duct ligated rats显示文摘AIM: To evaluate in bile duct ligated rats whether there were progressive alterations of renal function without changes in histopathology. METHODS: Male Wistar rats were submitted to sham-surgery or bile duct ligation (BDL) and divided according to the post-procedure time (2, 4 and 6-wk). To determine renal function parameters, rats wereplaced in metabolic cages and, at the end of the experiment, blood and urine samples were obtained. Histology and hydroxyproline content were analyzed in liver and renal tissue. RESULTS: Rats with 2 wk of BDL increased free water clearance (P = 0.02), reduced urinary osmolality (P = 0.03) and serum creatinine (P = 0.01) in comparison to the sham group. In contrast, rats at 6 wk of BDL showed features of HRS, including signif icant increase in serum creatinine and reductions in creatinine clearance, water excretion and urinary sodium concentration. Rats with 4 wk of BDL exhibited an intermediate stage of renal dysfunction. Progressive hepatic f ibrosis according to post-procedure time was confirmed by histology. The increased levels of liver hydroxyproline contrasted with the absence of structural changes in the kidney, as assessed by histology and unchanged hydroxyproline content in renal tissue. CONCLUSION: Our data show that BDL produced progressive renal dysfunction without structural changes in the kidney, characterizing HRS. The present model will be useful to understand the pathophysiology of HRS. | Regina M Pereira Robson AS dos Santos Eduardo A Oliveira Virgínia HR Leite Filipi LC Dias Alysson S Rezende Lincoln P Costa Lucíola S Barcelos Mauro M Teixeira Ana Cristina Sim■es e Silva | 2008 | World Journal of Gastroenterology2008，14，28： | 2 |
| 5 | Blood Pressure and Giancoma 显示文摘 | Costa ~P Arcieri ES Harris A | 2009 | Br J Ophthalmol2009，93，10： | 1 |
| 6 | Biodiesel compatibility with carbon steel and HDPE parts显示文摘 | Marcia Marie Maru Marcia Maria Lucchese Cristiano Legnani Welber Gianini Quirino Andrea Balbo Isabele Bulh?es Aranha Lílian Terezinha Costa Cecília Vilani Lídia ágata de Sena Jailton Carreteiro Damasceno Talita dos Santos Cruz Leandro Reis Lidízio Rui Fer | 2009 | Fuel Processing Technology2009，，9： | 1 |
| 7 | Strapping the spinal cord: An innovateive experimental model of CNS injury in rats 显示文摘 | da Costa ES Carvalho AL Martinez AM | 2008 | J Neurosci Methods2008，170，1： | 1 |
| 8 | Variational elliptic problems which are nonquadratic at infinity显示文摘 | Costa D G Magalh(a)es C A | 1994 | Nonlinear Anal1994，23，11： | 1 |
| 9 | The Wnt signaling pathway regulates Nalm-16 b-cell precursor acute lymphoblastic leukemic cell line survival and etoposide resistance显示文摘 | Thiago l_S Costa ES Lopes DV | 2010 | Biomed Pharmacother2010，64，1： | 1 |
| 10 | Impact of trace metals on denitrification in estuarine sediments of the Douro River estuary, Portugal 显示文摘 | MAGALH? ES C COSTA J TEIXEIRA C | 2007 | Marine Chemistry2007，107，3： | 1 |
| 11 | Normal hematopoiesis is maintained by activated bone marrow CD4^+ T cells 显示文摘 | Monteiro JP Benjamin A Costa ES | 2005 | Blood2005，105，4： | 1 |
| 12 | A probabilistic ap- proach for the evaluation of minimal residual disease by muhiparameter flow cytometry in leukemic B-cell chronic lymphopmlifemtive disorders 显示文摘 | Pedreira CE Costa ES Almeida J | 2008 | Cytometry Part A2008，73，： | 1 |
| 13 | Multiprobe chloride sensor for in situ monitoring of reinforced concrete structures显示文摘 | M.F. Montemor J.H. Alves A.M. Sim?es J.C.S. Fernandes Z. Louren?o A.J.S. Costa A.J. Appleton M.G.S. Ferreira | 2006 | Cement and Concrete Composites2006，，3： | 1 |
| 14 | Variational elliptic problems which are nonquadratic at infinity显示文摘 | Costa D G Magalhāes C A | | 0，，： | 1 |
| 15 | Evaluation of free radical-scavenging and antihemolytic activities of quince (Cydonia oblonga) leaf: A comparative study with green tea (Camellia sinensis) 显示文摘 | Costa R Magalh es A Pereira J | 2009 | Food Chem Toxicol2009，47，4： | 1 |
| 16 | Robust Position Sliding-mode Control of a Permanent Magnet Motor Using A Load-torque Observer显示文摘 | JHMMIN JESTEV ES Pf COSTA | 1993 | New York:PESS IEEE1993，，： | 1 |
| 17 | Allergy to cow's milk pro- teins: what contribution does hypersensitivity in skin tests have to this diagnosis? 显示文摘 | Costa AJ Sarinho ES Motta ME | 2011 | Pediatr Allergy Immunol2011，22，12： | 1 |
| 18 | Photodiagnosis and treatment of condyloma acuminatum using 5-aminolevulinic acid and homemade devices 显示文摘 | Inada NM Costa MM Guimar? es OC | 2012 | Photodiagnosis photodyn Ther2012，9，1： | 1 |
| 19 | Comparison of two- and three-dimensional ultrasonography in the evaluation of fetal heart: image quality and time spent in the exam显示文摘 | Hélio Antonio Guimar?es Filho Lavoisier Linhares Dias da Costa Edward Araujo Júnior Sebasti?o Marques Zanforlin Filho Cláudio Rodrigues Pires Luciano M. M. Nardozza Antonio Fernandes Moron Rosiane Mattar | 2007 | Archives of Gynecology and Obstetrics2007，，3： | 1 |
| 20 | Breast cancer metastasis to the pituitary gland显示文摘 | Magalh(a)es JF Bacchin RP Costa PS | 2014 | Arq Bras Endocrinol Metabol2014，58，8： | 1 |
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