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| 1 | Combined carriership of TLR9 -1237C and CD14 -260T alleles enhances the risk of developing chronic relapsing pouchitis显示文摘AIM: To investigate the single nucleotide polymorphisms (SNPs) in genes involved in bacterial recognition and the susceptibility to pouchitis or pouchitis severity.METHODS: Analyses of CD14 -260C>T, CARD15/NOD2 3020insC, Toll-like receptor (TLR)4 +896A>G,TLR9 -1237T>C, TLR9+ 2848G>A, and IRAKM +22148G>A SNPs were performed in 157 ileal-pouch anal anastomosis (IPAA) patients (79 patients who did not develop pouchitis, 43 infrequent pouchitis patients,35 chronic relapsing pouchitis patients) and 224 Italian Caucasian healthy controls.RESULTS: No significant differences were found in SNP frequencies between controls and IPAA patients.However, a significant difference in carriership frequency of the TLR9-1237C allele was found between the infrequent pouchitis and chronic relapsing pouchitis groups [P = 0.028, odd's ratio (OR) = 3.2, 95%CI = 1.2-8.6].This allele uniquely represented a 4-locus TLR9 haplotype comprising both studied TLR9 SNPs in Caucasians.Carrier trait analysis revealed an enhanced combined carriership of the alleles TLR9 -1237C and CD14 -260T in the chronic relapsing pouchitis and infrequent pouchitis group (P = 0.018, OR = 4.1, 95%CI = 1.4 -12.3).CONCLUSION: There is no evidence that the SNPs predispose to the need for IPAA surgery. The significant increase of the combined carriership of the CD14 -260T and TLR9 -1237C alleles in the chronic relapsing pouchitis group suggests that these markers identify a subgroup of IPAA patients with a risk of developing chronic or refractory pouchitis. | KM Lammers S Ouburg SA Morré JBA Crusius P Gionchetti F Rizzello C Morselli E Caramelli R Conte G Poggioli M Campieri AS Pea | 2005 | World Journal of Gastroenterology2005，11，46： | 7 |
| 2 | Stress and the welfare of cultured fish 显示文摘 | Conte F S | 2004 | Applied Animal Behaviour Science2004，86，34： | 1 |
| 3 | Metal catalysis in oxidation by peroxides, electrophilic oxygen transfer from anionic, coordinatively saturated molybdenum peroxo complexes显示文摘 | CAMPESTRINI S CONTE V FURIA F D | 1988 | Org Chem1988，53，： | 1 |
| 4 | Growth and feed efficiency of white sturgeon (Acipenser transmontanus) sub-yearling at different feeding rates 显示文摘 | Hung S SO Lutes P B Conte F S | 1989 | Aquaculture1989，80，12： | 1 |
| 5 | Long-term follow-up of neuroblastoma-associated op-soclonus-myoclonus-ataxia syndrome显示文摘 | De Grandis E Parodi S Conte M Angelini P Battaglia F Gan-dolfo C | 2009 | Neuropediatrics2009，40，3： | 1 |
| 6 | Surgical management of neonatal coarctation显示文摘 | CONTE S LACOUR-GAYET F SERRAF A | 1995 | J Thorac Cardiovasc Surg1995，109，： | 1 |
| 7 | Stress and the welfare of cultured fish 显示文摘 | Conte F S | 2004 | Appl Anim Behav Sci2004，86，： | 1 |
| 8 | Growth and feed efficiency of white sturgeon(Acepenser transmontanus)subyearlings at diferent feeding rates显示文摘 | Hung S S O Lutes P B Conte F S | 1989 | Aquaculture1989，80，： | 1 |
| 9 | Mimicking the vanadium bromoperoxidases reactions:mild and selective bromination of arenes and alkents in a two-phase system显示文摘 | Conte V D Furia F D Moro S | 1994 | Tetrahedron Letter1994，35，41： | 1 |
| 10 | Mimicking the vanadium bromperoxidases reactions:mild and selective bromination of arenas and alkenes in a two-phase system显示文摘 | Conte V Di Furia F Maro S | 1994 | Tetrahedron Lett1994，35，40： | 1 |
| 11 | Stress and the welfare of cultured fish显示文摘 | Conte F S | | 0，，3： | 1 |
| 12 | Alltrans retinoie acid induces free radical generation and modulate antioxidant enzyme activities in rat sertoli cells显示文摘 | CONTE F M GOMES S E BEHR G A | 2006 | Mol Cell Biochem2006，285，12： | 1 |
| 13 | Phase Ⅱ/Ⅲ weekly nab-paclitaxel plus gemcitabine or carboplatin versus gemcitabine/carboplatin as first-line treatment of patients with metastatic triple-negative breast cancer (the tnAcity study): study protocol for a randomized controlled trial显示文摘 | Yardley D A Brufsky A Coleman R E Conte P F Cortes J Glück S | 2015 | Trials2015，16，： | 1 |
| 14 | Bats are a major natural reservoir for hepaeiviruses and pegiviruses显示文摘 | Quan P L Firth C Conte J M Williams S H Zam- brana-Torrelio C M Anthony S J Ellison J A Gilbert A T Kuzmin I V Niezgoda M Osinubi M O Re-cuenco S Markotter W Breiman R F Kalemba L Malekani J Lindblade K A Rostal M K Ojeda-Flores R Suzan G Davis L B Blau D M Ogunkoya A B Alvarez Castillo D A Moran D Ngam S Akaibe D Agwanda B Briese T Epstein J H Daszak P Rup- precht C E Holmes E C Lipkin W I | 2013 | PNAS2013，110，20： | 1 |
| 15 | Prevalence of hepati- tis B and hepatitis C in an orthopaedics and traumatology ward显示文摘 | VILLANI C CONTE S CHIOZZI F | 2001 | La Chirurg/a Degli Organi Di Movimento2001，86，2： | 1 |
| 16 | Growth and feed efficiency of white sturgeon (Acipenser transmontanus) sub-yearlings at different feeding rates显示文摘 | Lutes P B Conte F S | 1989 | Aquaculture1989，80，： | 1 |
| 17 | Optimum feeding rate of white sturgeon (Acipenser transmontanus) yearlings under commercial production conditions 显示文摘 | Conte F S Lutes P B | 1995 | Appl Aquac1995，5，： | 1 |
| 18 | Growth of white sturgeon fed seven commercial feeds 显示文摘 | Hung S S O Conte F S Frost F | 1998 | Aquaculture1998，161，： | 1 |
| 19 | 牧绵羊日粮中添加栗子单宁提取物和挤压亚麻籽对牛奶产量、成分和脂肪酸组成的影响显示文摘单宁通过与日粮蛋白质形成非降解配合物,通过调节一些细菌的活动,干扰瘤胃内蛋白质和脂质的代谢,包括多不饱和脂肪酸的生物氢化,其是一种生物活性物质。试验研究日粮中添加栗子水解单宁提取物对母羊奶产量和品质的影响。将经产的萨尔达母羊96头在泌乳中期阶段均匀分为两组,对照组(C组)和补充栗子单宁提取物(CHE组),每组48头,进行饲养试验。两组动物每天在相同的牧场放牧8 h,牧场是黑麦草、燕麦和白三叶的混合牧场(比例为1??1??1)。两组日粮仅在精料补充上不同。对照组母羊每头每天饲喂不含栗子单宁提取物的浓缩料450 g,而CHE组母羊每头每天饲喂与对照组原料相同且添加80.0 g·kg-1栗单宁提取物干物质的日粮500 g。为获得等蛋白和等能日粮处理动物的预期干物质采食量,试验对两组母羊浓缩料饲喂量进行了计算。浓缩料中添加板栗单宁使羊产乳量得到较大提高,提高了18.64%(P<0.001)。两组羊奶的酪蛋白部分组成无差异,CHE组酪蛋白指数比对照组更大(P=0.034)。关于脂肪酸组成,与对照组相比,CHE组奶的ω-3脂肪酸的浓度更高,C组和CHE组总脂质中α-亚麻酸含量分别为2.18、2.57 g·100 g-1,而CHE组共轭亚油酸和trans11C18??1的百分比较小,C和CHE两组总脂质中CLA含量分别为2.20·100 g-1、1.85 g·100 g-1(P=0.001),trans11C18??1含量分别为3.89、3.57 g·100 g-1(P=0.001)。栗子单宁提取物实际剂量的使用可以改善放牧绵羊对日粮亚麻籽的反应,从而提高奶中α-亚麻酸浓度。 | Buccioni A Serra A Minieri S Mannelli F Cappucci A Benvenuti D Rapaccini S Conte G Mele M | 2015 | 饲料博览2015，0，9： | 1 |
| 20 | Risk factors,medical therapies and perioperative events in limb salvage surgery:Obervartions feom the PREVENT Ill multicenter trial显示文摘 | Conte M S Bandyk D F Clowes A W | 2005 | J Vase Surg2005，42，3： | 1 |
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