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28篇 您的检索式：作者名="Conchillo"

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	题名	作者	年代	出处	被引量
1	Mitochondrial protection by low doses of insulin-like growth factor-Ⅰin experimental cirrhosis显示文摘AIM: To characterize the mitochondrial dysfunction in experimental cirrhosis and to study whether insulin-like growth factor-Ⅰ(IGF-Ⅰ) therapy (4 wk) is able to induce beneficial effects on damaged mitochondria leading to cellular protection. METHODS: Wistar rats were divided into three groups: Control group, untreated cirrhotic rats and cirrhotic rats treated with IGF-Ⅰtreatment (2 μg/100 g bw/d). Mitochondrial function was analyzed by flow cytometry in isolated hepatic mitochondria, caspase 3 activation was assessed by Western blot and apoptosis by TUNEL in the three experimental groups. RESULTS: Untreated cirrhotic rats showed a mitochon- drial dysfunction characterized by a significant reduction of mitochondrial membrane potential (in status 4 and 3); an increase of intramitochondrial reactive oxigen species (ROS) generation and a significant reduction of ATPase activity. IGF-Ⅰtherapy normalized mitochondrial func-tion by increasing the membrane potential and ATPase activity and reducing the intramitochondrial free radical production. Activity of the electron transport complexes Ⅰand Ⅲ was increased in both cirrhotic groups. In addition, untreated cirrhotic rats showed an increase of caspase 3 activation and apoptosis. IGF-Ⅰtherapy reduced the expression of the active peptide of caspase 3 and resulted in reduced apoptosis.	Raquel Pérez María García-Fernández Matías Díaz-Sánchez Juan E Puche Gloria Delgado Marian Conchillo Jordi Muntané Inma Castilla-Cortázar	2008	World Journal of Gastroenterology2008，14，17：	11
2	Combined effect of cooking (grilling and roasting) and chilling storage (with and without air) on lipid and cholesterol oxidation in chicken breast显示文摘	CONCHILLO D A ASTIASARAN I	2003	Journal of Food Protection2003，66，5：	1
3	Is type Ⅲ intestinal metaplasia an obligatory precancerous lesion in intestinal-type gastric carcinoma? 显示文摘	Conchillo JM Houben G de Bruine A	2001	Eur J Cancer Pre2001，10，4：	1
4	Is type Ⅲ intestinal metaplasia an obligatnry precancerous lesion in intestinal-type gastric carcinoma? 显示文摘	Conchillo J M Houben G de Bruine A	2001	Eur J Cancer Prey2001，10，4：	1
5	Insulin-like growth factor I (IGF-I)replacement therapy increases albumin concentration in liver cirrhosis:results of a pilot randomized controlled clinical trial显示文摘	Conchillo M de Knegt R J Payeras M Castilla-Cortazar I, Frystyk J, Flyvbjerg A, Yoshizawa C, Jansen PL, Scharschmidt B, Prieto J		0，，：	1
6	Insulin-like growth factor Ⅰ (IGF-Ⅰ) replacement therapy increases albumin concentration in liver cirrhosis:results of a pilot randomized controlled clinical trial显示文摘	Conchillo M de knegt RJ Payeras M		0，，04：	1
7	Overexpression of GATA2 predicts an adverse prognosis for patients with acute myeloid leukemia and it is associated with distinct molecular abnormalities显示文摘	Vicente C Vazquez I Conchillo A	2011	Leukemia2011，26，3：	1
8	Acid and nonacid reflux patterns in patients with erosive esophagitis and nonerosive reflux disease (NERD):a study using intraluminal impedance monitoring显示文摘	Conchillo J M Schwartz M P Selimah M	2008	Dig Dis Sci2008，53，6：	1
9	Re- view article: the clinical relevance of transient lower oesophageal sphincter relaxations in gastro - oesophageal reflux disease 显示文摘	KESSING BF CONCHILLO JM BREDENOORD AJ	2011	Aliment Pharm Therap2011，33，6：	1
10	Insulin-like growth factor I (IGF-I) replacement therapy increases albumin concentration in liver cirrhosis: Results of a pilot randomized controlled clinical trial显示文摘	Mariam Conchillo Robert J. de Knegt Marina Payeras Jorge Quiroga Bruno Sangro Jose-Ignacio Herrero Inma Castilla-Cortazar Jan Frystyk Allan Flyvbjerg Carl Yoshizawa Peter L.M. Jansen Bruce Scharschmidt Jesús Prieto	2005	Journal of Hepatology2005，，4：	1
11	Acid and non-acid reflux patterns in patients with erosive esophagitis and non-erosive reflux disease (NERD): a study using intraluminal impedance monitoring 显示文摘	Conchillo J M Schwartz M P Selimah M	2008	Dig Dis Sci2008，53，6：	1
12	Insulin-like growth factor Ⅰ (IGF-Ⅰ )replacement therapy increases albumin concentration in liver cirrhosis: results of a pilot randomized controlled clinical trial 显示文摘	Conchillo M de Knegt R J Payeras M	2005	J Hepatol2005，43，：	1
13	Hyperemesis gravidarum and severe liver enzyme elevation显示文摘	José M Conchillo Ger Koek	2002	Journal of Hepatology2002，，1：	1
14	Insulin-like growth factor I (IGF-I) replacement therapy increases albumin concentration in liver cirrhosis : results of a pilot randomized controlled clinical trial 显示文摘	Conchillo M de Knegt R J Payeras M	2005	J Hepatol2005，43，4：	1
15	Insulin-like growth factor I (IGF-I) and liver cirrhosis 显示文摘	Conchillo M Prieto J Quiroga J	2007	Rev Esp Enferm Dig2007，99，3：	1
16	Acid and Non-Acid Reflux Patterns in Patients with Erosive Esophagitis and Non-Erosive Reflux Disease (NERD): A Study Using Intraluminal Impedance Monitoring显示文摘	José M. Conchillo Matthijs P. Schwartz Mohamed Selimah Melvin Samsom Daniel Sifrim André J. Smout	2008	Digestive Diseases and Sciences2008，，6：	1
17	Endoscopic gastric volume reduction with a novel articulating plication device is safe and effective in the treatment of obesity (with video)显示文摘	Tessa Verlaan Givan F. Paulus Lisbeth M.H. Mathus-Vliegen Lilianne A.M.L. Veldhuyzen José M. Conchillo Nicole D. Bouvy Paul Fockens	2014	Gastrointestinal Endoscopy2014，，：	1
18	Acid and non-acid reflux patterns in patients with erosive esophagitis and non-erosive reflux disease: NERD: a study using intraluminal impedance monitoring显示文摘	Conchillo JM Schwartz MP Selimah M	2008	Dig Dis Sci2008，53，6：	1
19	Acid and nonacid reflux patterns in patients with erosive esophagitis and nonerosive reflux disease (NERD):a study using intraluminal impedance monitoring显示文摘	Conchillo JM Schwartz MP Selimah M	2008	Dig Dis Sci2008，53，：	1
20	Acid and non-acid reflux patterns in patients with erosiveesophagitis and non-erosive reflux disease(NERD):a study using intraluminal impedance monitoring显示文摘	Conchillo JM Schwartz MP Selimah M	2008	Dig Dis Sci2008，53，：	1

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