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| 1 | Contrast-enhanced ultrasound evaluation of hepatic microvascular changes in liver diseases显示文摘AIM:To assess if software assisted-contrast-enhanced ultrasonography (CEUS) provides reproducible perfusion parameters of hepatic parenchyma in patients affected by chronic liver disease. METHODS:Forty patients with chronic viral liver disease, with (n = 20) or without (n = 20) cirrhosis, and 10 healthy subjects underwent CEUS and video recordings of each examination were then analysed with Esaote's Qontrast software. CEUS dedicated software Qontrast was used to determine peak (the maximum signal intensity), time to peak (TTP), region of blood value (RBV) proportional to the area under the time-intensity curve, mean transit time (MTT) measured in seconds and region of blood flow (RBF). RESULTS:Qontrast-assisted CEUS parameters displayed high inter-observer reproducibility (k coefficients of 0.87 for MTT and 0.90 TTP). When the region of interest included a main hepatic vein, Qontrast-calculated TTP was significantly shorter in cirrhotic patients (vs non-cirrhotics and healthy subjects) (71.0 ± 11.3 s vs 82.4 ± 15.6 s, 86.3 ± 20.3 s, P < 0.05). MTTs in the patients with liver cirrhosis were significantly shorter than those of controls (111.9 ± 22.0 s vs 139.4 ± 39.8 s, P < 0.05), but there was no significant difference between the cirrhotic and non-cirrhotic groups (111.9 ± 22.0 s vs 110.3 ± 14.6 s). Peak enhancement in the patients with liver cirrhosis was also higher than that observed in controls (23.9 ± 5.9 vs 18.9 ± 7.1, P = 0.05). There were no significant intergroup differences in the RBVs and RBFs. CONCLUSION:Qontrast-assisted CEUS revealed reproducible differences in liver perfusion parameters during the development of hepatic fibrogenesis. | Francesco Ridolfi Teresa Abbattista Paolo Busilacchi Eugenio Brunelli | 2012 | World Journal of Gastroenterology2012，18，37： | 10 |
| 2 | Antithrombin III (ATILL) replacement therapy in patients with sepsis and/or postsurgical complications: a controlled double-blind, randomized, multicenter study显示文摘 | F. Baudo T. M. Caimi F. deCataldo A. Ravizza S. Arlati G. Casella D. Carugo G. Palareti C. Legnani L. Ridolfi R. Rossi A. D’Angelo L. Crippa D. Giudici G. Gallioli A. Wolfler G. Calori | 1998 | Intensive Care Medicine1998，，4： | 2 |
| 3 | 对高风险的胰腺吻合行胰管置管胰液外引流:一组病例对照研究显示文摘 | G. Balzano G. Capretti A. Zerbi C. Ridolfi N. Pecorelli D. Valerio 张频捷(摘译) 赵红川(审校) | 2009 | 肝胆外科杂志2009，17，4： | 2 |
| 4 | Diagnosis of liv- er cirrhosis by transit-time analysis at contrast-enhanced ulra- sonography 显示文摘 | Abbattista T Ridolfi F Ciabattoni E | 2008 | Radiol Med2008，113，： | 1 |
| 5 | Diagnosis of liver cirrhosis by transit-time analysis at contrast-enhanced ultrasonography显示文摘 | Abbattista T Ridolfi F Ciabattoni E | | 0，，06： | 1 |
| 6 | Contrast-enhanced ultrasound to evaluate the severity of chronic hepatitis C显示文摘 | F. Ridolfi T. Abbattista F. Marini A. Vedovelli P. Quagliarini P. Busilacchi E. Brunelli | 2007 | Digestive and Liver Disease2007，，10： | 1 |
| 7 | Multivariate nonlinear prediction of river flows显示文摘 | Porporato A Ridolfi L | 2001 | Journal of Hydrology2001，248，： | 1 |
| 8 | Multivariate nonlinear prediction of river flows显示文摘 | PORPORATO A RIDOLFI L | 2001 | Journal of Hydrology2001，248，： | 1 |
| 9 | Contrast-enhanced ultrasound to evaluate the severity of chronic hepatitis C显示文摘 | Ridolfi F Abbattista T Marini F | | 0，，10： | 1 |
| 10 | Unexpected highresponse rate to traditional therapy after dendritic cell-based vac-cine in advanced melanoma:update of clinical outcome and sub-group analysis显示文摘 | Ridolfi L Petrini M Fiammenghi L | 2010 | Clin Dev Immunol2010，2010，50： | 1 |
| 11 | Effect of alloying elements onthermal contraction and crack susceptibility during in-mold solidi-fication 显示文摘 | Ridolfi M T Vito A D Ferro L | 2008 | Metallurgical and Materials Transactions B2008，39，4： | 1 |
| 12 | Detecting determinism and nonlinearity in riverflow time series显示文摘 | Ridolfi L | 2003 | Hydrology Sci J2003，48，5： | 1 |
| 13 | Intracellular signaling pathways involved in acetaldehyde-induced collagen and fibronectin gene expression in human hepatic stellate cells显示文摘 | Ridolfi F Di-Sario A | 2001 | Hepatology2001，33，5： | 1 |
| 14 | lntralesional granulocyte-monocyte colony-stimulating factor followed by subcutaneous interleukin-2 in metastatic melanoma: a pilot study in elderly patients 显示文摘 | Ridolfi L Ridolfi R Ascari-Raccagni A | 2001 | J Eur Acad Dermatol Venereol2001，15，3： | 1 |
| 15 | Intraedlular signaling pathways involved in acetaldehyde-induced collagen and fibronectin gene expression in human hepatic stellate cells 显示文摘 | Svegliati-Baroni G Ridolfi F Di Sario A | 2001 | Hepatology2001，33，5： | 1 |
| 16 | Intracellular signaling pathways involved in acetaldehyde induced collagen and fibronectin gene expression in human hepatic stellate cells显示文摘 | Svegliati Baroni G Ridolfi F Di Sario A | 2001 | J Hepatol2001，33，5： | 1 |
| 17 | Delayed gastrointestinal recovery after abdominal operation - role of alvimopan 显示文摘 | Berger NG Ridolfi TJ Ludwig KA | 2015 | Clin Exp GastroenternI2015，，8： | 1 |
| 18 | Regulation of ERK/JUN/ pTOS6K in two rat models of liver injury and fibrosis显示文摘 | SVEGLIATI-BARONI G RIDOLFI F | 2003 | J Hepatol2003，39，4： | 1 |
| 19 | Containerisation in the Mediterranean: between global ocean routeways and feeder services 显示文摘 | Giovanni Ridolfi | 1999 | GeoJournal1999，，48： | 1 |
| 20 | Multivariate nonlinear prediction of river flows显示文摘 | Porporato A Ridolfi L | 2001 | Journal of Hydrology2001，，248： | 1 |
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