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| 1 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 2 | Chest neoplasms with infectious etiologies显示文摘A wide spectrum of thoracic tumors have known or suspected viral etiologies.Oncogenic viruses can be classified by the type of genomic material they contain.Neoplastic conditions found to have viral etiologies include post-transplant lymphoproliferative disease,lymphoid granulomatosis,Kaposi's sarcoma,Castleman's disease, recurrent respiratory papillomatosis,lung cancer,malignant mesothelioma,leukemia and lymphomas.Viruses involved in these conditions include Epstein-Barr virus, human herpes virus 8,human papillomavirus,Simian virus 40,human immunodeficiency virus,and Human T-lymphotropic virus.Imaging findings,epidemiology and mechanism of transmission for these diseases are reviewed in detail to gain a more thorough appreciation of disease pathophysiology for the chest radiologist. | Carlos S Restrepo Melissa M Chen Santiago Martinez-Jimenez Jorge Carrillo Catalina Restrepo | 2011 | World Journal of Radiology2011，3，12： | 6 |
| 3 | Usefulness of biodegradable polydioxanone stents in the treatment of postsurgical colorectal strictures and fistulas显示文摘 | F. Pérez Roldán P. González Carro M. Villafá?ez García S. Aoufi Rabih M. Legaz Huidobro N. Sánchez-Manjavacas Mú?oz O. Roncero García-Escribano M. Ynfante Ferrús E. Bernardos Martín F. Ruiz Carrillo | 2012 | Endoscopy2012，，03： | 2 |
| 4 | In vitro antibacterial effects of antilipopolysaccharide DNA aptamer-C1 qrs complexes 显示文摘 | Bruno J G Carrillo M P Phillips T | 2008 | Folia Microbiol(Praha)2008，53，4： | 1 |
| 5 | Daily rhythms of insulin and glucose levels in the plasma of sea bass Dicentrarchus labrax after experimental feeding显示文摘 | Gutierrez J Carrillo M Zanuy S | 1984 | General and Comparative Endocrinology1984，55，3： | 1 |
| 6 | Peripheral inflammatory and fibrinolytic markers in adolescents with growth hormone deficiency:Relation to postprandial dyslipidemia显示文摘 | Lanes R Paoli M Carrillo E | | 0，，05： | 1 |
| 7 | Electrocardiographic changes of ST-elevation myocardial infarction in patients with complete occlusion of the left main trunk without collateral circulation : differential diag- nosis and clinical considerations 显示文摘 | Fiol M Carrillo A Rodriguez A | 2012 | J Electrocardiol2012，45，5： | 1 |
| 8 | Video thoracoscopy expedites the diagnosis and treatment of penetrating diaphragmatic injuries显示文摘 | Briz JE Carrillo EH | 2001 | Surg Endosc2001，15，： | 1 |
| 9 | Effect of al- kali pretreatment on cellulase hydrolysis of wheat straw: Kinetic study 显示文摘 | CARRILLO F LIS M J COLOM X | 2005 | Process Biochemistry2005，40，10： | 1 |
| 10 | Characterization of the entire cystatin gene family in barley and their target cathepsin L-like eysteine -proteases, partners in the hordein mobilization during seed germination 显示文摘 | MARTINEZ M CAMBRA I CARRILLO L | 2009 | Plant Physiology2009，151，3： | 1 |
| 11 | Evaluation of the effect of nutrient ratios on biosurfactant production by Serratia marcescens using a Box-Behnken design显示文摘 | CARRILLO T R GARCIA X M PENASCO I Z | 2011 | Colloids and Surfaces B: Biointerfaces2011，86，2： | 1 |
| 12 | Long pho-toperiod on sea cages delays timing of first spermiation and enhances growth in male European sea bass (Di-centrarchus labrax) 显示文摘 | Carrillo M Begtashi I Rodriguez L | 2010 | Aquaculture2010，299，14： | 1 |
| 13 | Influence of high molecular weight (HMW)and low molecular weight (LMW) glutenin subunits controlled Glu-1 and Glu-3 loci on durum wheat quality显示文摘 | Brites C Carrillo J M | 2001 | Cereal Chemistry2001，78，： | 1 |
| 14 | Influence of high molecular weight and low molecular weight glutenin subunits controlled by Glu - 1 and Glu - 3 loci on durum wheat quality显示文摘 | Brites C Carrillo J M | 2001 | Cereal Chem2001，78，1： | 1 |
| 15 | Induction of a protective antibody response to food and month disease virus in mice following oral or parenteral immunization with alfalfa transgenic plants expressing the viral structural protein VP1显示文摘 | Wigdorovitz A Carrillo C Dus Santos M J | 1999 | Virology1999，255，2： | 1 |
| 16 | Brief treatment with an aromatase inhibitor during sex differentiation causes chromosomally female salmon to develop as normal, functional males显示文摘 | Piferrer F Zanuy S Carrillo M | 1994 | Journal of experimental zoology1994，270，： | 1 |
| 17 | Influence of high molecular weight (HMW) and low molecular weight (LMW) glutenin subunits controlled by Glu-1 and Glu-3 loci on durum wheat quality 显示文摘 | Brites C Carrillo J M | 2001 | Cereal Chem2001，78，： | 1 |
| 18 | Dual-specificity phos- phatases are imaplicated in severe hyperplasia and lack of response to fgf-23 of uremic parathyroid glands from rats显示文摘 | Roman P Carrillo N Naves M | 2012 | Endocrinology2012，153，4： | 1 |
| 19 | Development of transgenic alfalfa plants containing the foot and mouth disease virus structural polyprotein gene P1 and its utilization as an experimental immunogen显示文摘 | DUS SANTOS M J CARRILLO C ARDILA F | 2005 | Vaccine2005，23，15： | 1 |
| 20 | Peripheral inflammatory and fibrinolytic markers in adolescents with growth hormone deficiency:Relation to postprandial dyslipidemia显示文摘 | Lanes R Paoli M Carrillo E | 2004 | J Pediatr2004，145，5： | 1 |
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