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| 1 | Joint effect among p53, CYP1A1, GSTM1 polymorphism combinations and smoking on prostate cancer risk: an exploratory genotype-environment interaction study显示文摘瞄准:与前列腺癌症的调节的人冒的风险的一个环境因素在联合估计几个基因因素的角色。我们集中于与房间控制联系的低外显率的基因的等位基因变体, detoxification 进程并且吸烟。方法:在盒子控制研究,我们比较了与他们的前列腺癌症风险带 p53cd72 职业人员等位基因, CYP1A1 M1 等位基因和 GSTM1 空遗传型的人。结果:为带专业版的吸烟者的联合风险 * 并且 M1 * ,专业版 * 并且 GSTM1null 或 GSTM1 0 和 CYP1A1 M1 * 变体显著地更高(机会比率[或] :13.13, 95% 信心间隔[CI ] :2.41-71.36;或:3.97, 95% CI:1.13-13.95 并且或:6.87, 95% CI:1.68-27.97,分别地) 不为参考组,并且为不抽烟的人与那相比是重要的。或为在 p53cd72, GSTM1 和 CYP1A1 之中的联合,在吸烟者的 M1 断然并且显著地与不抽烟的人相比并且与通常认为的最低风险组相比与前列腺癌症风险被联系(或:8.87, 95% CI:1.25-62.71 ) 。结论:我们的结果建议那在修改前列腺癌症的一个重要角色在学习人口上冒的风险的 p53cd72, CYP1A1, GSTM1 等位基因和吸烟的戏的联合,哪个带易受影响的遗传型的吸烟者可能有的工具显著地更高的风险比带非易受影响的遗传型的那些。 | Luis A. Quinones Carlos E. Irarrázabal Claudio R. Rojas Cristian E. Orellana Cristian Acevedo Christian Huidobro Nelson E. Varela Dante D. Cáiceres | 2006 | Asian Journal of Andrology2006，8，3： | 6 |
| 2 | Glutathione peroxidase activity in cell cultures from different regions of human epididymis显示文摘Aim: To study the secretory activity and androgen regulation of glutathione peroxidase (GPx) in epithelial cell cultures from human epididymis. Methods: Tissue was obtained from patients undergoing therapeutic orchidectomy for prostatic cancer. Epithelial cell cultures were obtained from the caput, corpus and cauda epididymides. Enzymatic activity was measured in conditioned media by colorimetric methods in absence or presence of 1, 10 or 100 nmol·L^-1 testosterone. The effect of 1 μmol·L^-1 flutamide was also evaluated. Results: GPx activity was higher in cultures from corpus and cauda than caput epididymidis. The presence of different concentrations of testosterone increase enzyme activity in cell cultures from all epididymal regions. Addition of flutamide reverses the androgen dependent increase of GPx activity. Conclusion: GPx activity is secreted from human epididymal cells in a region dependent manner and is regulated by androgens. | Enrique Castellon Hernan Rioseco Juan Rojas Michel Royer Eduardo Salas Hoctor Contreras Christian Huidobro | 2005 | Asian Journal of Andrology2005，7，1： | 2 |
| 3 | Usefulness of biodegradable polydioxanone stents in the treatment of postsurgical colorectal strictures and fistulas显示文摘 | F. Pérez Roldán P. González Carro M. Villafá?ez García S. Aoufi Rabih M. Legaz Huidobro N. Sánchez-Manjavacas Mú?oz O. Roncero García-Escribano M. Ynfante Ferrús E. Bernardos Martín F. Ruiz Carrillo | 2012 | Endoscopy2012，，03： | 2 |
| 4 | Development and validation of a HPLC method for the determination of sertraline and three non-chiral related impurities 显示文摘 | Ferrarini A Huidobro AL Pellati F | 2010 | J Pharm Biomed Anal2010，53，2： | 1 |
| 5 | A comparison between two methods (Warner-Bratzler and texture profile analysis) for testing either raw meat or cooked meat显示文摘 | de HUIDOBRO F R MIGUE E BLAZQUEZ B | 2005 | Meat Science2005，69，3： | 1 |
| 6 | Major components of honey analysis by near-infrared transflectance spectroscopy 显示文摘 | Garcia-Alvarez M Huidobro J F Hermida M | 2000 | Journal of Agriculture and Food Chemistry2000，48，： | 1 |
| 7 | Major components of honey analysis by near-in- frared transflectance spectroscopy 显示文摘 | GARCfA -ALVAREZ M HUIDOBRO J F HERMIDA M | 2000 | Journal of Agri- cultural and Food Chemistry2000，48，11： | 1 |
| 8 | A review of the analytical methods to determine organic acids in grape juices and wines显示文摘 | Ines Mato Silvia Suarez-Luque Jose F Huidobro | 2005 | Food Research International2005，38，： | 1 |
| 9 | Acomparison between two methods (Warner-Bratzler andtexture profile analysis) for testing either raw meat or cookedmeat显示文摘 | F Ruiz de Huidobro E Miguel B Bla'zquez | 2005 | Meat Science2005，69，： | 1 |
| 10 | A comparison between two methods (Warner-Bratzler and texture profile analysis) for testing either raw meat or cooked meat显示文摘 | de Huidobro F R Miguel E Bla'zquez B | 2005 | Meat Science2005，69，3： | 1 |
| 11 | A DNA methylation signature associated with aberrant promoter DNA hypermethylation of DNMT3B in human colorectal cancer显示文摘 | Covadonga Huidobro Rocío G. Urdinguio Ramón María Rodríguez Cristina Mangas Vincenzo Calvanese Pablo Martínez-Camblor Cecilia Ferrero Adolfo Parra-Blanco Luis Rodrigo álvaro J. Obaya Laura Suárez-Fernández Aurora Astudillo Henar Hernando Esteban Ballestar | 2011 | European Journal of Cancer2011，，14： | 1 |
| 12 | Positive correlation between single or combined genotypes of CYP1 A1 and GSTM1 in relation to prostate cancer in Chilean people 显示文摘 | Acevedo C Opazo JL Huidobro | 2003 | Prostate2003，57，2： | 1 |
| 13 | Enzymatic determination of glycerol in honey显示文摘 | Huidobro | 1993 | Journal of Agricultural and Food Chemistry1993，41，： | 1 |
| 14 | Gemcitabine,cisplatin and vinorelbine as inducation chemotherapy followed by radical therapy in stage Ⅲ non-small cell lung cancer:a multicenter study of Galician-lung-cancer-group显示文摘 | Leon L Cueva-Banuelos JF Huidobro G | 2003 | Lung Cancer2003，40，2： | 1 |
| 15 | Neonatal screening for congenital adrenal hyperplasia: transitory elevation of 17-hydroxyprogesterone显示文摘 | Huidobro Fernandez B Echeverria Fernindez M Dulin Ifiiguez E | 2011 | J Pediatr Endocrinol Metab2011，24，34： | 1 |
| 16 | Rapid determination of minority organic acids in honey by high-performance liquid chromatography显示文摘 | Silvia Sua'rez-Luque Ine' s Mato Jose' F Huidobro etc | 2002 | Journal of Chro- matography A2002，955，： | 1 |
| 17 | Simple determination of main organic acids in grape juice and wine by using capillary zone electrophorcsis with direct UV detection 显示文摘 | Ines Mato Silvia Sua'rcz-Luquc Jose F Huidobro | 2007 | Food Chemistry2007，102，： | 1 |
| 18 | Incidence of hypocalcemia after total thyroidectomy显示文摘 | Gac E P Caban: T P Amat V J Huidobro G F Rossi F R Rodriguez F F | 2007 | Rev Med Chil2007，135，： | 1 |
| 19 | Quality index method developed for raw gihhead seabream (Sparus aurata)显示文摘 | Huidobro A Pastor A Tejada M | 2000 | Journal of Food Science2000，65，7： | 1 |
| 20 | A review of the analytical methods to determine organic acids in grape juices and wines 显示文摘 | Mato I Su6rez-Luque S Huidobro J F | 2005 | Food Research International2005，38，10： | 1 |
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