|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Nocardia infections among immunomodulated inflammatory bowel disease patients:A review显示文摘Human nocardiosis,caused by Nocardia spp.,an ubiquitous soil-borne bacteria,is a rare granulomatous disease close related to immune dysfunctions.Clinically can occur as an acute life-threatening disease,with lung,brain and skin being commonly affected.The infection was classically diagnosed in HIV infected persons,organ transplanted recipients and long term corticosteroid treated patients.Currently the widespread use of immunomodulators and immunossupressors in the treatment of inflammatory diseases changed this scenario.Our purpose is to review all published cases of nocardiosis in immunomodulated patients due to inflammatory diseases and describe clinical and laboratory findings.We reviewed the literature concerning human cases of nocardiosis published between 1980 and 2014 in peer reviewed journals.Eleven cases of nocardiosis associated with anti-tumor necrosis factor(TNF) prescription(9 related with infliximab and 2 with adalimumab) were identified; 7 patients had inflammatory bowel disease(IBD),4 had rheumatological conditions; nocardia infection presented as cutaneous involvement in 3 patients,lung disease in 4 patients,hepatic in one and disseminated disease in 3 patients.From the 10 cases described in IBD patients 7 were associated with anti-TNF and 3 with steroids and azathioprine.In conclusion,nocardiosis requires high levels of clinical suspicion and experience of laboratory staff,in order to establish a timely diagnosis and by doing so avoid worst outcomes.Treatment for long periods tailored by the susceptibility of the isolated species whenever possible is essential.The safety of restarting immunomodulators or anti-TNF after the disease or the value of prophylaxis with cotrimoxazole is still debated. | Candida Abreu Nuno Rocha-Pereira António Sarmento Fernando Magro | 2015 | World Journal of Gastroenterology2015，21，21： | 18 |
| 2 | Thiol-peptide level and proteomic changes in response to cadmium toxicity in Oryza sativa L. roots显示文摘 | Roberta Aina Massimo Labra Pietro Fumagalli Candida Vannini Milena Marsoni Ulisse Cucchi Marcella Bracale Sergio Sgorbati Sandra Citterio | 2006 | Environmental and Experimental Botany2006，，3： | 2 |
| 3 | 利用稳定氮同位素跟踪污水氮对沿海生态系统的影响显示文摘本文评价了稳定氮同位素(δ^(15)N)用于阐述污水氮对沿海生态系统的影响,重点描述波罗的海希默兰湾个案的情况,该海湾接纳主要以溶解的无机氮(DIN)形式排泄的富含^(15)N的三级处理过的污水。巨藻(Fucus vesiculosus)和表层沉积物的δ^(15)N梯度变化曲线示踪到距排泄口24km污水衍生氮的情况。但是高δ^(15)N值(>7‰)说明污水在10km的范围内影响最大。强化的三级处理前后巨藻δ^(15)N值的比较研究表明,从距排泄口约24km到12km范围内污水氮的空间影响是减弱的,而且对于最近生长的组织中的较高的海洋δ^(15)N值来说也是下降的。沉积物中δ^(15)N的记载表明,在污水氮含量最大的年份里随着沉积物中δ^(15)N的急剧增加污水对该湾有机物的生产已造成重大的影响。当污水氮将明显的同位素特征引入系统时以及当它对有机物质的生产已产生主导影响时,生物群和沉积物中的δ^(15)N值可用来跟踪污水氮在水生生态系统中的时空影响。 | Candida Savage 高战朝 | 2005 | AMBIO-人类环境杂志2005，34，2： | 2 |
| 4 | Outcome of isolated antenatal hydronephrosis: a prospective cohort study显示文摘 | Graziela M. Coelho Maria Candida F. Bouzada Alamanda K. Pereira Bruno F. Figueiredo Maria Rafaela S. Leite Danielly S. Oliveira Eduardo A. Oliveira | 2007 | Pediatric Nephrology2007，，10： | 2 |
| 5 | A Critical Overview of Internal and External Cylin- der Contact Force Models 显示文摘 | Pereira Candida M Ramalho Amilcar L Ambr6si Jorge A | 2011 | Nonlinear Dynamics2011，63，： | 1 |
| 6 | Effects of methotrexate on inflammatory alterations induced by obesity: An in vivo and in vitro study显示文摘 | Caroline Candida DeOliveira Simone Coghetto Acedo érica Martins Ferreira Gotardo Patricia de Oliveira Carvalho Thalita Rocha José Pedrazzoli Alessandra Gambero | 2012 | 2012 (1-2)2012，，1： | 1 |
| 7 | Gene expression programming: a new adaptive algorithm for mlving problerns显示文摘 | Candida Ferreira | 2001 | Complex Systems2001，13，2： | 1 |
| 8 | Gene expression programming:A new adaptivealgorithm for solving problems显示文摘 | Candida F | 2001 | Complex Systems2001，13，2： | 1 |
| 9 | Gene expression programming: a new adaptive algorithm for solving problems显示文摘 | Candida Ferreira | 2001 | Complex Systems2001，13，2： | 1 |
| 10 | Procalcitonin:a possible marker of invasive fungal infection in high risk patients?显示文摘 | Candida BSI | 2011 | J Prev Med Hyg2011，52，： | 1 |
| 11 | Husbands' and wives' percep- tions of marital fairness across the family life cycle显示文摘 | Petersen Candida C | 1990 | The I - ntemational Journal of Aging and Human Development1990，31，3： | 1 |
| 12 | RAC/ROP GTPases:‘ hubs’ for signal integration and diversification in plants显示文摘 | NIBAU CANDIDA WU HEN-MING CHEUNG ALICE Y | 2006 | Trends in Plant Science2006，11，6： | 1 |
| 13 | A Practical Synthesis of 7-Azaindolylcarboxy-endo-tropanamide(DF 1012)显示文摘 | Marcello A Roberto A Candida CM | 2003 | Organic Process Research & Development2003，7，： | 1 |
| 14 | Co-alignment in the resource–performance relationship: strategy as mediator显示文摘 | Linda F. Edelman Candida G. Brush Tatiana Manolova | 2004 | Journal of Business Venturing2004，，3： | 1 |
| 15 | Arabidopsis thaliana plants overexpressing thylakoidal ascorbate peroxidase show increased resistance to Paraquat induced photooxidative stress and to nitric oxide-induced cell death显示文摘 | IRENE MURGIA DELIA TARANTINO CANDIDA VANNIN | 2004 | Plant2004，38，6： | 1 |
| 16 | Doctoral Education in the Field of Entrepreneurship显示文摘 | Candida G. Brush | 2003 | Journal of Management2003，，3： | 1 |
| 17 | Gene expression programming: a new adaptive algorithm for solving problems 显示文摘 | Candida Ferreira | 2001 | Complex Systems2001，13，2： | 1 |
| 18 | The landscape of social entrepreneurship显示文摘 | Heidi Neck Candida Brush Elaine Allen | | 0，，： | 1 |
| 19 | Rifampicin induced flu-syndrome and toxicpsychosis显示文摘 | Salafia A Candida | 1992 | Indian J Leprosy1992，64，4： | 1 |
| 20 | Detection of Schistosoma mansoni eggs in feces through their interaction with paramagnetic beads in a magnetic field显示文摘 | Candida FT Erli N Renata B | 2007 | PLoS Negl Trop Dis2007，1，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员