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| 1 | Low hypoxia inducible factor-1α(HIF-1α)expression in testicular germ cell tumors--a major reason for enhanced chemosensitivity?显示文摘The molecular basis for enhanced chemosensitivity of testicular germ cell tumors(GCT)has been an area of great interest,as it could potentially give us therapeutic leads in other resistant malignancies.Thus far,however,the increased sensitivity of GCT has been variously attributed to multiple factors—an inability to detoxify cisplatin,a lack of export pumps,an inability to repair the DNA damage,an intact apoptotic cascade and lack of p53 mutation;but a unifying underlying etiology leading to the aforementioned processes and having a translational implication has so far been elusive.Herein,we offer evidence to support a potential significant role for the previously demonstrated low hypoxia inducible factor-1α(HIF-1α)expression in mediating the general exquisite chemosensitivity of testicular GCT,through the aforementioned processes.This molecular mechanism based hypothesis could have a significant translational implication in platinum refractory GCT as well as other platinum resistant malignancies. | niraj shenoy roxana dronca fernando quevedo stephen a boorjian john cheville brian costello manish kohli thomas witzig lance pagliaro | 2017 | Chinese Journal of Cancer Research2017，29，4： | 4 |
| 2 | Ultrastructural morphmetric analysis of BrucelIa abortus-infected trophoblasts in experimental placentitis显示文摘 | Anderson T D Cheville N F | 2006 | Pathol2006，124，： | 1 |
| 3 | Nephron sparing surgery for appropriately selected renal cell carcinoma between 4 and 7 cm results in outcome similar to radical nephrectomy显示文摘 | LEIBOVICH B C BLUTE M CHEVILLE J C | 2004 | J Urol2004，171，3： | 1 |
| 4 | Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma显示文摘 | Cheville JC Lohse CM Zincke H | 2003 | Am J Surg Pathol2003，27，5： | 1 |
| 5 | Pathogenesis of virulent Newcastle disease in chickens显示文摘 | Cheville N F Riley J Ritchie A E | 1972 | J Am Vet Med Assoc1972，，： | 1 |
| 6 | Costimulatory B7- H1 in renal cell carcinoma patients: Indicator of tumor aggressive- ness and potential therapeutic target 显示文摘 | Thompson RH Gillett MD Cheville JC | 2004 | Proc Natl Acad Sci U S A2004，101，17： | 1 |
| 7 | Fatigue, dyspnea, and cough comprise a persistent symptom cluster up to five years after diagnosis with lung cancer显示文摘 | Cheville AL Novotny PJ Sloan JA | 2011 | J Pain Symptom Manage2011，42，2： | 1 |
| 8 | Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma显示文摘 | Cheville JC Lohse CM Zincke H | 2003 | Am J Surg Pathol2003，27，： | 1 |
| 9 | Renal Cell Carcinoma in the Solitary Kidney: An Analysis of Complications and Outcome After Nephron Sparing Surgery显示文摘 | Reza Ghavamian John C. Cheville Christine M. Lohse Amy L. Weaver Horst Zincke Michael L. Blute | 2002 | The Journal of Urology2002，，2： | 1 |
| 10 | Nephron sparing surgery for appropriately selected renal cell carcinoma between 4 and 7 cm results in outcome similar to radical nephrectomy显示文摘 | Leibovich BC Blute ML Cheville JC | 2004 | J Urol2004，171，3： | 1 |
| 11 | Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma显示文摘 | Cheville JC Lohse CM Zincke H | 2003 | Am J Surg Pathol2003，27，5： | 1 |
| 12 | Carcinosarcoma of the prostate: report of 21 cases显示文摘 | Dundore PA Cheville JC Nascimento AG | 1995 | Cancer1995，76，6： | 1 |
| 13 | A protocol for performing extended lymph node dissection using primary tumor pathological features for patients treated with radical nephrectomy for clear cell renal cell carcinoma显示文摘 | Blute ML Leibovich BC Cheville JC | 2004 | J Urol2004，172，2： | 1 |
| 14 | A prospective cohort study defining utilities using time trade-offs and the Euroqol-5D to assess the impact of cancer-related lymphedema显示文摘 | Cheville AL Almoza M Courmier JN | | 0，，15： | 1 |
| 15 | Mate pair se- quencing of whole- genome- amplified DNA following laser capture microdissection of prostate cancer 显示文摘 | MURPHY S J CHEVILLE J C ZAREI S | 2012 | DNA Res2012，19，5： | 1 |
| 16 | Is renal sinus fat invasion the same as perinephric fat invasion for pT3a renal cell car- cinoma显示文摘 | Thompson RH Leibovich BC Cheville JC | 2005 | J Uro12005，174，： | 1 |
| 17 | Randomized controlled trial of maintaining quality of life during radiotherapy for advanced cancer显示文摘 | Matthew M. Clark Teresa A. Rummans Pamela J. Atherton Andrea L. Cheville Mary E. Johnson Marlene H. Frost Janis J. Miller Jeff A. Sloan Karen M. Graszer Jean G. Haas Jean M. Hanson Yolanda I. Garces Katherine M. Piderman Maria I. Lapid Pamela J. Netzel Ja | 2012 | Cancer2012，，4： | 1 |
| 18 | Para ganglioma of the urinary bladder: can biologic poten tialbe predicted? 显示文摘 | C heng L Leibovich B C Cheville J C | 2000 | Cancer2000，88，4： | 1 |
| 19 | A scoring algorithm to predict survival for patients with metastatic dear cell renal cell carcinoma:a stratification tool for prospective clinical trials显示文摘 | Leibovich BC Cheville JC Lohse CM | 2005 | J Urol2005，174，5： | 1 |
| 20 | Sarcomatoid renal cell carcinoma: an examinalion of underlying histologic subtype and an analysis of associations with patient outcome显示文摘 | CHEVILLE JOHN C LOHSE | 2004 | Am J Surg Pathol2004，28，4： | 1 |
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