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| 1 | Enhanced secondary pollution offset reduction of primary emissions during COVID-19 lockdown in China显示文摘To control the spread of the 2019 novel coronavirus(COVID-19),China imposed nationwide restrictions on the movement of its population(lockdown)after the Chinese New Year of 2020,leading to large reductions in economic activities and associated emissions.Despite such large decreases in primary pollution,there were nonetheless several periods of heavy haze pollution in eastern China,raising questions about the well-established relationship between human activities and air quality.Here,using comprehensive measurements and modeling,we show that the haze during the COVID lockdown was driven by enhancements of secondary pollution.In particular,large decreases in NOx emissions from transportation increased ozone and nighttime NO_(3)radical formation,and these increases in atmospheric oxidizing capacity in turn facilitated the formation of secondary particulate matter.Our results,afforded by the tragic natural experiment of the COVID-19 pandemic,indicate that haze mitigation depends upon a coordinated and balanced strategy for controlling multiple pollutants. | Xin Huang Aijun Ding Jian Gao Bo Zheng Derong Zhou Ximeng Qi Rong Tang Jiaping Wang Chuanhua Ren Wei Nie Xuguang Chi Zheng Xu Liangduo Chen Yuanyuan Li Fei Che Nini Pang Haikun Wang Dan Tong Wei Qin Wei Cheng Weijing Liu Qingyan Fu Baoxian Liu Fahe Chai Steven JDavis Qiang Zhang Kebin He | 2021 | National Science Review2021，8，2： | 47 |
| 2 | Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009-2013显示文摘 | Ying Peng Song-Hua Chen Le Zhang Bin Chen Ming-Wu Zhang Tie-Niu He Fei Wang Cheng-Liang Chai Lin Zhou Yu Zhang Xiao-Meng Wang Zhongwei Jia | 2017 | Chinese Medical Journal2017，，17： | 13 |
| 3 | Accuracy of physical examination, ultrasonography, and magnetic resonance imaging in predicting response to neo-adjuvant chemotherapy for breast cancer显示文摘 | CHEN Man ZHAN Wei-wei HAN Bao-san FEI Xiao-chun JIN Xiao-long CHAI Wei-min WANG Deng-bing SHEN Kun-wei WANG Wen-ping | 2012 | Chinese Medical Journal2012，，11： | 12 |
| 4 | Plasma soluble C-type lectin-like receptor-2 is associated with the risk of coronary artery disease显示文摘Accumulating evidence suggests that C-type lectin-like receptor-2(CLEC-2)plays an important role in atherothrombosis.In this case-control study,we investigated the association between CLEC-2 and incidence of coronary artery disease(CAD).A total of 216 patients,including 14 cases of stable angina pectoris(SAP,non-ACS)and 202 cases of acute coronary syndrome(ACS),and 89 non-CAD control subjects were enrolled.Plasma levels of soluble CLEC-2(sCLEC-2)were measured using the enzyme-linked immunosorbent assay(ELISA).Compared with the control group(65.69(55.36–143.22)pg/mL),the plasma levels of sCLEC-2 were significantly increased in patients with CAD(133.67(88.76–220.09)pg/mL)and ACS(134.16(88.88–225.81)pg/mL).The multivariate adjusted odds ratios(95%confidence interval)of CAD reached 2.01(1.52–2.66)(Ptrend<0.001)for each 1-quartile increase in sCLEC-2.Restricted cubic splines showed a positive dose-response association between sCLEC2 and CAD incidence(Plinearity<0.001).The addition of sCLEC-2 to conventional risk factors improved the C statistic(0.821 vs.0.761,P=0.004)and reclassification ability(net reclassification improvement:57.45%,P<0.001;integrated discrimination improvement:8.27%,P<0.001)for CAD.In conclusion,high plasma sCLEC-2 is independently associated with CAD risk,and the prognostic value of sCLEC-2 may be evaluated in future prospective studies. | Min Fei Li Xiang Xichen Chai Jingchun Jin Tao You Yiming Zhao Changgeng Ruan Yiwen Hao Li Zhu | 2020 | Frontiers of Medicine2020，14，1： | 5 |
| 5 | Several significant hydrographic characteristics and their formation mechanism in the South China Sea during the spring and summer of 1998显示文摘On the basis of the CTD data obtained by the two cruises before and after summer monsoon burst (25th May, 1998), several significant hydrographic characteristics, their variation and formation mechanism in the South China Sea (SCS) are analyzed. The results show that the Kuroshio water intrudes into the SCS in the form of loop current, and its main part is limited to the east of 118°E near the Luzon Strait. Then it continuously extends westwards under the influence of the large-scale circulation, and has a distinct impact on the area north of 16°N. There are two high temperature and low salinity regions:west off Luzon and east off Vietnam respectively. One region west off Luzon strengthens obviously after summer monsoon burst, the other east off Vietnam shows a tendency of weakening in the north and strengthening in the south. The formation of these two high temperature and low salinity regions is related to the anti-cyclonic eddies existing in this area, besides, it is also related to the high temperature feature west of Luzon, the influx of Sulu Sea water and the influence of the large-scale air circulation. There is a cold region below the depth of 50 m in the south of Zhongsha Islands, and it strengthens after monsoon burst. The formation of cold water is related to the upwelling there. | Xu Jianping 1,2,Chai Fei 2,3,Liu Zenghong 1,2,Zhu Bokang 1,2 1.Second Institute of Oceanography,State Oceanic Administration,Hangzhou 310012,China. 2.Key Laboratory of Ocean Dynamic Processes and Satellite Oceanography of State Oceanic Administration, Hangzhou 310012, China 3.School of Marine Science, University of Maine, Orono, ME 04469-5741,USA | 2003 | Acta Oceanologica Sinica2003，22，4： | 5 |
| 6 | Using cell membrane chromatography and HPLC-TOF/MS method for in vivo study of active components from roots of Aconitum carmichaeli显示文摘An offline two-dimensional system combining a rat cardiac muscle cell membrane chromatography time-of-flight mass spectrometry(CMC-TOF/MS)with a high performance liquid chromatography time-of-flight mass spectrometry(HPLC-TOF/MS)was established for investigating the parent components and metabolites in rat urine samples after administration of the roots of Aconitum carmichaeli.On the basis of the analysis of the first dimension,retention components of the urine sample were collected into 30 fractions(one fraction per minute).Then offline analysis of the second dimension was carried out.34 compounds including 24 parent alkaloids and 10 potential metabolites were identified from the dosed rat urine,and then binding affinities of different compounds on cell membranes were compared and influences of some functional groups on activity were estimated with the semi-quantification and curve fitting method.As a result,binding affinities decreased along with the process of deacylation,debenzoylation and demethylation,which may be related to the alleviation of toxicity in the procedure of herb processing or metabolism.Moreover,some minor components in rat urine(Songorine,14-benzoylneoline,Deoxyaconitine,etc.)exerted relatively strong affinity on cell membranes are worth exploring.The results delivered by the system suggest that the CMC can be applied to in vivo study. | Yan Cao Xiao- Fei Chen Di- Ya Lu Xin Dong Guo-Qing Zhang Yi- Feng Chai | 2011 | Journal of Pharmaceutical Analysis2011，1，2： | 4 |
| 7 | Strengthening and toughening mechanism of a Cu-bearing high-strength low-alloy steel with refined tempered martensite/bainite(M/B)matrix and minor inter-critical ferrite显示文摘The microstructure–mechanical property relationship of a Cu-bearing low-carbon high-strength low-alloy steel,subjected to a novel multistage heat treatment including quenching(Q),lamellarization(L)and tempering(T),is presented.Yield strength of 989.5 MPa and average toughness at-80℃of 41 J were obtained in this steel after quenching and tempering(QT)heat treatments.Specimen QLT gained a little lower yield strength(982.5 MPa),but greatly enhanced average toughness at-80℃(137 J).To further clarify the strengthening and toughening mechanisms in specimen QLT,parameters of microstructural characteristic and crack propagation process were compared and analyzed for specimens Q,QL,QT and QLT.The microstructure of tempered martensite/bainite(M/B)in specimen QT changed to refined tempered M/B matrix mixed with minor IF(inter-critical ferrite)in specimen QLT.Cu-rich precipitates existed in tempered M/B for both specimens QT and QLT,as well as in IF.Compared with QT,adding a lamellarization step before tempering made the effective grains of specimen QLT refined and also led to coarser Cu-rich precipitates in tempered M/B matrix.The weaker strengthening effect of coarser Cu-rich precipitates should be a key reason for the slightly lower yield strength in specimen QLT than in specimen QT.No austenite was found in all specimens Q,QL,QT and QLT.Specimen QLT showed purely ductile fracture mode at-80℃due to the refined effective grains.The greatly improved toughness is mainly attributed to the enhanced energy of crack propagation.The combination of refined microstructure,softened matrix and deformation of minor'soft'IF during crack propagation led to the most superior toughness of specimen QLT among all specimens. | Fei Zhu Feng Chai Xiao-bing Luo Zheng-yan Zhang Cai-fu Yang | 2021 | Journal of Iron and Steel Research(International)2021，28，4： | 4 |
| 8 | Pollution characteristics and health risk assessment of polycyclic aromatic hydrocarbons and nitrated polycyclic aromatic hydrocarbons during heating season in Beijing显示文摘Polycyclic aromatic hydrocarbons(PAHs)and their nitrated derivatives(NPAHs)attract continuous attention due to their outstanding carcinogenicity and mutagenicity.In order to investigate the diurnal variations,sources,formation mechanism,and health risk assessment of them in heating season,particulate matter(PM)were collected in Beijing urban area from December 26,2017 to January 17,2018.PAHs and NPAHs in PM were quantitatively analyzed via gas chromatography-mass spectrometry(GC-MS).Average daily concentrations of PAHs and NPAHs were(78±54)ng/m^(3)and(783±684)pg/m^(3),respectively.The concentrations of them were significantly higher at nighttime than at daytime,and NPAHs concentrations were 1-2 orders of magnitude lower than PAHs concentrations.In the heating season,the dominant species of PAHs include benzo[b]fluoranthene,fluoranthene,pyrene,and chrysene,while 9-nitroanthracene,2+3-nitrofluoranthene,and 2-nitropyrene were dominant species for NPAHs.NPAHs were found to have a single peak during heating and to be primarily distributed in the 0.4-0.7μm particle size.Primary emissions such as biomass burning,coal combustion,and traffic emissions were the major sources of PAHs.NPAHs were produced by the primary source of vehicle emissions and the secondary reaction triggered by OH radicals,as well as biomass burning during daytime.According to the health risk assessment,the total carcinogenic risk was higher in adults than in children.While upon oral ingestion,the carcinogenic risk in children was higher than that of adults,but the risk of adults was higher than children through skin contact and respiratory inhalation. | Xurong Bai Jie Wei Yanqin Ren Rui Gao Fahe Chai Hong Li Fei Xu Yuxue Kong | 2023 | Journal of Environmental Sciences2023，，1： | 3 |
| 9 | Role of tetraspanin CD151–α3/α6 integrin complex: Implication in angiogenesis显示文摘 | Wei-Feng Liu Hou-Juan Zuo Bo-lan Chai Dan Peng Yu-Jie Fei Jing-Yang Lin Xiao-Hui Yu Dao-Wen Wang Zheng-Xiang Liu | 2011 | International Journal of Biochemistry and Cell Biology2011，，4： | 3 |
| 10 | Burden of pancreatitis and associated risk factors in China,1990 to 2019:a systematic analysis for the Global Burden of Disease Study 2019显示文摘Background: Pancreatitis is a common disease of the digestive system. Acute pancreatitis is one of the most common reasons for gastrointestinal hospital admission, and chronic pancreatitis significantly reduces quality of life. However, national epidemiological data on pancreatitis in China are lacking. This study aimed to quantify the disease burden of pancreatitis in China from 1990 to 2019.Methods: This study was based on the Global Burden of Disease Study 2019 dataset. Age-standardized rates of incidence (ASIR), prevalence (ASPR), mortality (ASMR), and disability-adjusted life years (DALYs) were used to describe the disease burden of pancreatitis, and estimated annual percentage change (EAPC) was used to indicate the average change in age-standardized rates. We also described the trend of pancreatitis-related mortality and DALYs, which are attributable to alcohol use by age and sex.Results: From 1990 to 2019, the ASIR, ASPR, ASMR, and age-standardized DALYs of pancreatitis in China decreased by 10.90, 1.50, 0.49, and 15.54 per 100,000, respectively, with EAPCs of -1.35 (95% uncertainty interval [UI]: -1.67, -1.02) and -0.37 (95% UI: -0.43, -0.31), -2.01 (95% UI: -2.07, -1.94) and -2.32 (95% UI: -2.37, -2.28), respectively. Recently, the numbers of incident and prevalent cases have risen, with estimates of 380,018 (95% UI: 308,669-462,767) and 493,765 (95% UI: 416,705-578,675), respectively, in 2019. Among men, the disease burden of pancreatitis was more severe than among women, and with variances in the distribution among different age groups. Age-standardized DALYs caused by alcohol-related pancreatitis have gradually worsened in the past decade, accounting for 34.09% of the total in 2019.Conclusions: The disease burden of pancreatitis in China has declined in the past 30 years, but the exacerbation of population aging poses a challenge to prevention and control of pancreatitis. Alcohol use has gradually become an important factor in the disease burden of pancreatitis in recent years. | Ke Han Shimin Chen Yang Song Chen Du Fei Gao Shaohua Liu Yao He Ningli Chai Enqiang Linghu Miao Liu | 2022 | Chinese Medical Journal2022，，11： | 3 |
| 11 | Effect of Doped Boron on the Properties of ZnO Thin Films Prepared by Sol-gel Spin Coating显示文摘 | WEN Bin LIU Chaoqian FEI Weidong WANG Hualin LIU Shimin WANG Nan CHAI Weiping | 2014 | Chemical Research in Chinese Universities2014，30，3： | 3 |
| 12 | The solar wind plasma upstream of Mars observed by Tianwen-1:Comparison with Mars Express and MAVEN显示文摘On the great journey to Mars,China’s first planetary exploration mission,the Tianwen-1 came within 26 million kilometers of Mars from 31 October 2020 to 25 January 2021 and was getting closer to its destination,the red planet,in search of answers to the cataclysmic climate change that occurred in Martian history.Both the escape of the Martian atmosphere and the loss of surface water were firmly influenced by solar activities.Tianwen-1 provided a unique chance to depict the solar wind streams between Earth and Mars during the minimum of Solar Cycle 25.During the three-month cruise phase of Tianwen-1,the solar wind flows were successively observed at Earth,Tianwen-1,and Mars.After the field of view correction and noise reduction,the solar wind velocity and density measured by Tianwen-1 show good agreement with those at Earth and Mars.The results indicate that the performance of the ion analyzer onboard the Tianwen-1 orbiter is reliable and stable.It is worth looking forward to the joint observations of ion escape with other Mars probes in the following Martian years. | Kai FAN Limei YAN Yong WEI Aibing ZHANG Linggao KONG Markus FRÄNZ Fei HE Lihui CHAI Chongjing YUAN Yuqi WANG Jun ZHONG Zhaojin RONG Zhonghua YAO Yongxin PAN Jun CUI Jiansen HE Wenya LI Binbin TANG Chi WANG | 2022 | Science China Earth Sciences2022，65，4： | 2 |
| 13 | Microstructure Evolution and Mechanical Behavior of Laser Melting Deposited TA15 Alloy at 500℃ under In-Situ Tension in SEM显示文摘TA15 alloy fabricated by laser melting deposition was investigated at 500℃ under tensile deformation. The damage behavior of microstructure was analyzed by the real time observation of the microstructure evolution, microcracks initiation and propagation using in-situ tensile equipment fitted in the SEM chamber. Finally, the mechanism of fracture was discussed. The result showed anisotropic mechanical properties in X-and Z-direction. The existence of columnar β grains and its orientation to the tensile direction were the major factors inducing the anisotropic mechanical properties. As compared to Z-direction specimen, high tensile strength was observed in X-direction specimen due to the resistance in slips propagation provided by the prior-β grain boundaries( β GBs). Accumulation of the cracks at prior β GB caused the shear fracture. In case of Z-direction specimen, parallel orientation of prior β GB and GB α with the tensile direction resulted in a homogeneous deformation. The high reduction of cross section showed the enhanced ductile characteristics at high temperature. | Muhammad Rizwan Junxia Lu Fei Chen Ruxia Chai Rafi Ullah Yuefei Zhang Ze Zhang | 2021 | Acta Metallurgica Sinica(English Letters)2021，34，9： | 2 |
| 14 | Thermal influence of ponding and buried warm-oil pipelines on permafrost: a case study of the China-Russia Crude Oil Pipeline显示文摘Buried pipelines are widely used for transporting oil in remote cold regions. However, the warm oil can induce considerable thermal influence on the surrounding frozen soils and result in severe maintenance problems. This paper presents a case study of the thermal influence of ponding and buried warm-oil pipelines on permafrost along the China-Russia Crude Oil Pipeline(CRCOP) in Northeast China. Since its operation in 2011, the operation of the warm-oil pipelines has led to rapid warming and thawing of the surrounding permafrost and development of sizable ponding along the pipeline route,which, in return, exacerbates the permafrost degradation. A field study was conducted along a 400-km long segment of the CRCOP in permafrost regions of Northeast China to collect the location and size information of ponding. A two-dimensional heat transfer model coupled with phase change was established to analyze the thermal influence of ponding and the operation of warm-oil pipelines on the surrounding permafrost. In-situ measured ground temperatures from a monitoring site were obtained to validate the numerical model. The simulation results show that ponding accelerates the development of the thaw bulb around the pipeline. The maximum thaw depth below the pipeline increases from 4 m for the case without ponding to 9 m for the case with ponding after 50 years of operation, and ponding directly above the pipe induces the maximum thaw depth. Engineering measures should be adopted to control the size or even eliminate surface water-rich ponding for the long-term performance of buried warm-oil pipelines. | YanHu Mu MingTang Chai GuoYu Li Wei Ma Fei Wang YaPeng Cao | 2020 | Research in Cold and Arid Regions2020，12，2： | 2 |
| 15 | Modeling the circulation in the Gulf of Tonkin, South China Sea显示文摘 | GAO Jingsong XUE Huijie CHAI Fei SHI Maochong | 2013 | Ocean Dynamics2013，63，8： | 1 |
| 16 | Influence of rolling speed on microstructure and mechanical properties of AZ31 Mg alloy rolled by large strain hot rolling显示文摘 | Fei Guo Dingfei Zhang Xusheng Yang Luyao Jiang Sensen Chai Fusheng Pan | 2014 | Materials Science & Engineering A2014，，： | 1 |
| 17 | Synthesis and biological activities of N-dichloroacetyl-2-n-propyl-1-oxa-4-aza-spiro-4, 5-decane显示文摘The title compound was synthesized and characterized by IR, 1HNMR and elemental analysis. The preliminary biological test showed that the compound protected maize against injury by imazethapyr to some extent. | YE Fei CHAI Chao | 2007 | Journal of Northeast Agricultural University(English Edition)2007，14，1： | 1 |
| 18 | Seasonal andinterannual variability of carbon cycle in South China Sea: athree-dimensional physical-biogeochemical modeling study显示文摘 | CHAI FEI LIU GUIMEI XUE HUIJIE 2009 | 2009 | Journal of Oceanography2009，65，5： | 1 |
| 19 | Uranium(VI) adsorption on graphene oxide nanosheets from aqueous solutions显示文摘 | Zijie Li Fei Chen Liyong Yuan Yalan Liu Yuliang Zhao Zhifang Chai Weiqun Shi | 2012 | Chemical Engineering Journal2012，，： | 1 |
| 20 | Physical-biological oceanographic coupling influencingphytoplankton and primary production in the South ChinaSea显示文摘 | NING XIUREN CHAI FEI XUE HUIJIE 2004 | 2004 | Journal of Geophysical Research2004，109，10： | 1 |
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