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10962篇 您的检索式:作者名="CARLSONS"
    题名 作者 年代 出处 被引量
1Reversible Middle Cerebral Artery Occlusion Without Craniectomy in Rats显示文摘Enrique Zea Longa Philip R. Weinstein Sara Carlson Robert Cummins 1989Stroke1989,,1:27
2青少年运动员早期专业化训练的生理学问题显示文摘青少年运动员是运动员的一个特殊群体 ,正面临着身体的生长发育和运动能力提高的双重压力。如何在不影响身体正常发育的同时又能在运动能力及身体素质等方面得到充分的发展 ,始终是青少年运动员在运动训练中亟待解决的问题。研究对处在发育期青少年的生理特点、运动能力及训练等问题进行了探讨 。金爱晶 Geraldine Naughton 王耀光 John Carlson Clermont Ferrand 2000体育科学2000,20,6:16
3Reversible Middle Cerebral Artery Occlusion Without Craniectomy in Rats显示文摘Enrique Zea Longa Philip R. Weinstein Sara Carlson Robert Cummins 1989Stroke1989,,1:9
4Fecal markers of inflammation used as surrogate markers for treatment outcome in relapsing inflammatory bowel disease显示文摘AIM: To evaluate fecal calprotectin (FC) as a surrogate marker of treatment outcome of relapse of inflammatory bowel disease (IBD) and, to compare FC with fecal myeloperoxidase (MPO) and fecal eosinophil protein X (EPX). METHODS: Thirty eight patients with IBD, comprising of 27 with ulcerative colitis (UC) and 11 with Crohn’s disease (CD) were investigated before treatment (inclusion), and after 4 and 8 wk of treatment. Treatment outcomes were evaluated by clinical features of disease activity and endoscopy in UC patients, and disease activity in CD patients. In addition, fecal samples were analyzed for FC by enzyme-linked immunosorbent assay (ELISA), and for MPO and EPX with radioimmunoassay (RIA). RESULTS: At inclusion 37 of 38 (97%) patients had elevated FC levels (> 94.7 μg/g). At the end of the study, 31 of 38 (82%) patients fulfilled predefined criteria of a complete response [UC 21/27 (78%); CD 10/11 (91%)]. Overall, a normalised FC level at the end of the study predicted a complete response in 100% patients, whereas elevated FC level predicted incomplete response in 30%. Normalised MPO or EPX levels predicted a complete response in 100% and90% of the patients, respectively. However, elevated MPO or EPX levels predicted incomplete response in 23% and 22%, respectively. CONCLUSION: A normalised FC level has the potential to be used as a surrogate marker for successful treatment outcome in IBD patients. However, patients with persistent elevation of FC levels need further evaluation. FC and MPO provide superior discrimination than EPX in IBD treatment outcome.Michael Wagner Christer GB Peterson Peter Ridefelt Per Sangfelt Marie Carlson 2008World Journal of Gastroenterology2008,14,36:9
5腕管综合征主要症状体征敏感性与特异性的比较显示文摘目的 比较腕管综合征 (carpaltunnelsyndrome ,CTS)主要症状、体征的敏感性与特异性。方法 对 10 1例 ( 162只手 )进行症状严重程度与功能状况的询问 ,感觉、运动功能的检查 ;其中 62只手在术后 6周再次测定。结果 162只患手中 15 8只具有典型症状 ( 98% )。Phalen征、前臂正中神经加压征、Semmes Weinstein单丝纤维测试阳性率分别为 98%、96%、82 %。 87%的患手出现肌力下降 ,拇短展肌肌力测定 (定量法 )结果显示 ,与徒手法相比 ,不同性别间、术前与术后的差异均具非常显著意义 (P <0 .0 1)。结论 典型症状、Phalen征、前臂正中神经加压征、拇短展肌肌力变化的敏感性与特异性最高 ,拇短展肌肌力定量法测定是判断腕管综合征严重程度、评定疗效的一个良好的客观指标。刘璠 Lois Carlson H.Kirk Watson 2004中华手外科杂志2004,20,3:8
6Femtosecond-laser sharp shaping of millimeter-scale geometries with vertical sidewalls显示文摘As femtosecond(fs)laser machining advances from micro/nanoscale to macroscale,approaches capable of machining macroscale geometries that sustain micro/nanoscale precisions are in great demand.In this research,an fs laser sharp shaping approach was developed to address two key challenges in macroscale machining(i.e.defects on edges and tapered sidewalls).The evolution of edge sharpness(edge transition width)and sidewall tapers were systematically investigated through which the dilemma of simultaneously achieving sharp edges and vertical sidewalls were addressed.Through decreasing the angle of incidence(AOI)from 0◦to−5◦,the edge transition width could be reduced to below 10µm but at the cost of increased sidewall tapers.Furthermore,by analyzing lateral and vertical ablation behaviors,a parameter-compensation strategy was developed by gradually decreasing the scanning diameters along depth and using optimal laser powers to produce non-tapered sidewalls.The fs laser ablation behaviors were precisely controlled and coordinated to optimize the parameter compensations in general manufacturing applications.The AOI control together with the parameter compensation provides a versatile solution to simultaneously achieve vertical sidewalls as well as sharp edges of entrances and exits for geometries of different shapes and dimensions.Both mm-scale diameters and depths were realized with dimensional precisions below 10µm and surface roughness below 1µm.This research establishes a novel strategy to finely control the fs laser machining process,enabling the fs laser applications in macroscale machining with micro/nanoscale precisions.Qiuchi Zhu Peixun Fan Nan Li Timothy Carlson Bai Cui Jean-François Silvain Jerry L Hudgins Yong Feng Lu 2021International Journal of Extreme Manufacturing2021,3,4:6
7转基因大麦中gfp基因的染色体位置及其表达(英文)显示文摘通过对大麦小孢子进行基因枪轰击获得 4株转绿色荧光蛋白基因 (gfp)的植株 (A、C、D、E) ,以gfp基因为探针进行荧光原位杂交 (FISH)研究转化植株中转基因插入位置和基因表达。 4个株系在染色体 7L(5HL)的不同位置都有一个插入点 ,而E株系在染色体 5S(7HS)还有第 2个插入点。所有的转基因T0 代植株都是半合子并在T1、T2代发生分离。D株系GFP未表达 ,但FISH和PCR分析表明gfp基因已成功插入其染色体。各株系在根尖和花粉中的GFP表达水平不同 :C株系在花粉表达强而在根尖表达中等 ;A株系在花粉中等表达而在根尖表达较淡 ;E株系则在根尖高表达 ,花粉中等表达。A和C株系在根尖和花粉的GFP分离都表现单位点特性 ,而E株系的根尖分离表现重叠作用 (15∶1)特征 ,但在花粉中表达GFP的频率低。PCR结果和 3个分离株系的根尖表达结果一致。D和E株系的GFP表达不正常可能和gfp基因插入位置或基因的结构有关。陈建民 Carlson A R 万建民 Kasha K J 2003Acta Genetica Sinica2003,30,8:6
8Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed.Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee 2014World Journal of Clinical Oncology2014,5,2:5
9Phase 2 trial of linifanib (ABT‐869) in patients with unresectable or metastatic hepatocellular carcinoma显示文摘Han Chong Toh Pei‐Jer Chen Brian I. Carr Jennifer J. Knox Sharlene Gill Peter Ansell Evelyn M. McKeegan Barry Dowell Michelle Pedersen Qin Qin Jiang Qian Frank A. Scappaticci Justin L. Ricker Dawn M. Carlson Wei Peng Yong 2012Cancer2012,,2:4
101987年美国股灾回顾显示文摘1987年10月19日,美国股票市场连同相关的期货和期权市场发生崩盘,当天的标准普尔500指数大跌近20%。Mark Carlson 张浩 李军 陈浩 周晓刚 王海慧 缪仕国 曹清 田晓琳 2007金融纵横2007,,16:4
11Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-Analysis显示文摘Ulrike Peters Shuo Jiao Fredrick R. Schumacher Carolyn M. Hutter Aaron K. Aragaki John A. Baron Sonja I. Berndt Stéphane Bézieau Hermann Brenner Katja Butterbach Bette J. Caan Peter T. Campbell Christopher S. Carlson Graham Casey Andrew T. Chan Jenny Chan 2012Gastroenterology2012,,:4
12On the relation between NDVI, fractional vegetation cover, and leaf area index显示文摘Toby N. Carlson David A. Ripley 1997Remote Sensing of Environment1997,,3:3
13华南栖霞组菊花石假象内正延性玉髓的成因及其地质意义显示文摘正延性玉髓常被视为干旱蒸发沉积环境的标志。正延性玉髓亦广泛分布于华南地区栖霞组菊花石 (目前绝大多数为天青石假象 )内。本文在天青石后期矿物交代序列识别的基础上 ,通过对菊花石内各期次碳酸盐交代矿物的电子探针分析 ,发现菊花石内正延性玉髓形成于富含硫酸根离子和镁离子的成岩介质条件中。结合已有的正延性玉髓研究报道和栖霞组的沉积、成岩作用环境特征分析 ,认为华南地区栖霞组菊花石内正延性玉髓的形成环境与高蒸发沉积环境或高盐度成岩环境无关。因此 。颜佳新 夏琼霞 E H Carlson 2001沉积学报2001,19,3:3
1410例女性生殖道的腺泡状软组织肉瘤的形态学、免疫组化和分子遗传学研究及鉴别诊断显示文摘腺泡状软组织肉瘤(ASPS)是一种起源未明,具有独特形态学特征的肿瘤,并具有ASPSCR1和TFE3的特征性融合基因。ASPS可罕见的发生在女性生殖道。作者对11例原诊断为女性生殖道部位的ASPS形态学特征进行总结研究,并使用一组抗体(TFE3、HMB45、melan-A、SMA、desmin和hCaldesmon)评估其免疫表型。此外,通过荧光原位杂交检测TFE3重排和ASPSCR1-TFE3融合基因。Schoolmeester J K Carlson J Keeney G L 许春伟(摘译) 张建中(审校) 2018临床与实验病理学杂志2018,34,6:3
15如何为工业机械选择安全光幕显示文摘如果能将安全光幕适当地应用到工业机械上,那么它就能够为工作人员和设备提供防护功能,可以显著降低工作人员和设备所面临的风险。Mike Carlson 张雪磊(译) 张良辰(译) 2010软件2010,31,8:3
16Pharmacogenetic Trial of a Cannabinoid Agonist Shows Reduced Fasting Colonic Motility in Patients With Nonconstipated Irritable Bowel Syndrome显示文摘Banny S. Wong Michael Camilleri Irene Busciglio Paula Carlson Lawrence A. Szarka Duane Burton Alan R. Zinsmeister 2011Gastroenterology2011,,5:3
17拇短展肌肌力定量检测的正常值及其可信度研究显示文摘目的 探讨拇短展肌肌力定量检测所得的正常值并分析其可信度。方法 用微电脑控制便携式肌力测量仪对 2 0~ 59岁的 2 97位正常人进行拇短展肌肌力正常值的测定。另 1组 12位正常人被用于组内及组间可信度测定。结果 各组正常值相当恒定 ,男性均大于女性。年龄、性别、优势与非优势手之间无显著差异。组内及组间可信度系数分别为 0 .92、0 .89。结论 该研究可为临床检测拇短展肌肌力提供客观、量化的正常值标准 。刘璠 Lois Carlson H.Kirk Watson 2004中华手外科杂志2004,20,1:3
18Phenomenological Model for Magnetorheological Dampers显示文摘B. F. Spencer Jr. S. J. Dyke M. K. Sain J. D. Carlson 1997Journal of Engineering Mechanics1997,,3:3
19百乐锌与氧化锌的比较试验:减少猪饲粮中的锌添加量同时维持猪的生长性能显示文摘猪的饲料原料通常含有适量浓度的锌(Zn)似乎可以满足猪对Zn的需要。研究证实,高浓度饲粮锌能刺激保育猪的生长和改善饲料利用率。但是,近年来养殖业日渐意识到饲粮中高浓度的矿物质会引起环境问题。人们也日益关注使用有机微量元素作为一种减少矿物质添加量和排泄量的方法。Wedekind(1990,1992)的试验表明,与硫酸锌(100%)相比,蛋氨酸锌(Zn—Met)的生物学效价在117%~206%。Carlson M S Veum T L 汪静霞 2007养猪2007,,3:2
20发生于乳房假体置入女性的间变性大细胞淋巴瘤:173例临床分析显示文摘背景与目的1962年,首例硅胶乳房假体被成功置人体内。1997年,报道了首例与硅胶乳房假体相关的间变性大细胞淋巴瘤(ALCL)。笔者回顾了已发表的37篇文献报道,共79例患者,并收集了94例未报道的病例。方法复习全世界文献。向作者和主治医师寻求文献或病例中缺少的临床和实验数据。由于需要收集的病例信息很多,有时需要在多个地点获得完整的病例信息。因为不是所有被询问的作者和主治医师均提供了信息,所以造成了数据的不完整。结果ALCL病变首先在假体周围血清肿内发现,其肿块附着于包膜,肿块可侵及皮肤,可在区域淋巴结发生,也可在乳房矫形手术中被发现。临床特点呈现多样化,有的仅表现为细胞学阳性结果,肿块自发消退;有的表现为转移性、难治性肿瘤,甚至死亡。其与假体填充物(盐水或硅胶)和置入假体目的(隆乳或乳房再造)没有相关性。在假体信息完整的病例中,患者体内至少置入过1个毛面假体;18例肿块扩散至包膜外,其中9例是致命的。主要的组织化学标记物是cD-30和Alk-1;其他标记物出现频率较低。乳房假体置入女性发生ALCL的风险评估范围是1/500000—1/3000000。结论与乳房假体相关的ALCL是一种新的淋巴瘤,其起源于瘢痕,具有部位和材料特异性,且临床表现呈现多样化,由多因素引起。Garry S. Brody Dennis Deapen Clive R. Taylor Lauren Pinter-Brown Sarah Rose House-Lightner James S. Andersen Grant Carlson Melissa G. Lechner Alan L. Epstein 朱利娜 高景恒 张晨 袁继龙 2015中国美容整形外科杂志2015,26,12:2
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