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| 1 | Testing for HCV Infection: An Update of Guidance for Clinicians and Laboratorians显示文摘 | Getchell Jane P Wroblewski Kelly E DeMaria Alfred Bean Christine L Parker Monica M Pandori Mark Dufour D Robert Busch Michael P Brecher Mark E Meyer William A Pesano Rick L Teo Chong-Gee Beckett Geoffrey A Araujo Aufra C Branson Bernard M D | 2013 | MMWR. Morbidity and Mortality Weekly Report2013，，18： | 3 |
| 2 | Emerging role of caldesmon in cancer:A potential biomarker for colorectal cancer and other cancers显示文摘Colorectal cancer(CRC) is a devastating disease, mainly because of metastasis. As a result, there is a need to better understand the molecular basis of invasion and metastasis and to identify new biomarkers and therapeutic targets to aid in managing these tumors. The actin cytoskeleton and actin-binding proteins are known to play an important role in the process of cancer metastasis because they control and execute essential steps in cell motility and contractility as well as cell division. Caldesmon(CaD) is an actin-binding protein encoded by the CALD1 gene as multiple transcripts that mainly encode two protein isoforms: High-molecular-weight CaD, expressed in smooth muscle, and low-molecular weight CaD(l-CaD), expressed in nonsmooth muscle cells. According to our comprehensive review of the literature, CaD, particularly l-CaD, plays a key role in the development, metastasis, and resistance to chemoradiotherapy in colorectal, breast, and urinary bladder cancers and gliomas, among other malignancies. CaD is involved in many aspects of the carcinogenic hallmarks, including epithelial mesenchymal transition via transforming growth factor-beta signaling, angiogenesis, resistance to hormonal therapy, and immune evasion. Recent data show that CaD is expressed in tumor cells as well as in stromal cells, such as cancerassociated fibroblasts, where it modulates the tumor microenvironment to favor the tumor. Interestingly, CaD undergoes selective tumor-specific splicing, and the resulting isoforms are generally not expressed in normal tissues, making these transcripts ideal targets for drug design. In this review, we will analyze these features of CaD with a focus on CRC and show how the currently available data qualify CaD as a potential candidate for targeted therapy in addition to its role in the diagnosis and prognosis of cancer. | Alya R Alnuaimi Vidhya A Nair Lara J Bou Malhab Eman Abu-Gharbieh Anu Vinod Ranade Gianfranco Pintus Mohamad Hamad Hauke Busch Jutta Kirfel Rifat Hamoudi Wael M Abdel-Rahman | 2022 | World Journal of Gastrointestinal Oncology2022，14，9： | 2 |
| 3 | Agenetic framework for floral patterning显示文摘 | Parcy F Nilsson O Busch M A Lee I Weigel D | 1998 | Nature1998，395，： | 1 |
| 4 | Regulatory elements of the floral homeotie gene AGAMOUS identified by phylogenetic footprinting and shadowing显示文摘 | HONG R L HAMAGUCHI L H BUSCH M A WEIGEL D | 2003 | The Plant Cell2003，15，： | 1 |
| 5 | Cardiomyocytes, endothelial ceils and car- diac fibroblasts: S100AI' s triple action in cardiovascular pathophysiology 显示文摘 | Rohde D Busch M Volkert A | 2015 | Future Cardio12015，11，3： | 1 |
| 6 | Methane and carbon dioxide adsorption-diffusion experiments on coal: upscaling and modeling显示文摘 | Busch A Gensterblum Y Krooss B M | 2004 | Coal Geology2004，，60： | 1 |
| 7 | Catheter-based radiofre- quency ablation therapy of the renal sympathetic nerve system for drug resistant hypertension in a patient with end-stage renal dis- ease显示文摘 | Prochnau D Lauten A Busch M | 2012 | Int J Cardiol2012，154，2： | 1 |
| 8 | Catheterbased radiofrequen- cy ablation therapy of the renal sympathetic-nerve system for drug resistant hypertension in a patient with end-stage renal disease 显示文摘 | Prochnau D Lauten A Busch M | 2012 | Int J Cardiol2012，154，2： | 1 |
| 9 | Investigation of high - pressure selective adsorption/desorption behavior of CO2 and CH4 on coals: An experimental study 显示文摘 | Busch A Gensterblum Y Krooss B M | 2006 | International Journal of Coal Geology2006，，1： | 1 |
| 10 | microRNAs in the regulation of dendritic cell functions in inflammation dnd athernsclerosis 显示文摘 | Busch M Zernecke A | 2012 | J Mol Med (Berl)2012，90，8： | 1 |
| 11 | A genetic framework for floral patterning显示文摘 | PARCY F NILSSON O BUSCH M A | 1998 | Nature1998，395，6702： | 1 |
| 12 | Evolution of methane sorption capacity of coal seams as a function of burial history - a case study from the Campine Basin, NE Belgium显示文摘 | Hildenbrand A Krooss B M Busch A Gaschnitz R | 2005 | International Journal of Coal Geology2005，19，： | 1 |
| 13 | Methane and carbon dioxide adsorption-diffusion experiments on coal: upscaling and modeling 显示文摘 | BUSCH A GENSTERBLUM Y BERNHARD M | 2004 | International Journal of Coal Geology2004，60，： | 1 |
| 14 | Transport properties of random arrays of dielectric cylinders显示文摘 | KIRCHNER A BUSCH K SOUKOULIS C M | 1998 | Phys Rev B1998，57，： | 1 |
| 15 | Modification to the capsid of the adenovirus vector that enhances dendritic cell infection and transgene - specific cellular immune responses 显示文摘 | Worgall S Busch A Rivara M | 2004 | J Virol2004，78，5： | 1 |
| 16 | Advanced glycation end products and β2-Microglobulin as predictors of carpal tunnel syndrome in hemodialysis patients 显示文摘 | Busch M Schwenzky A Franke S | 2012 | Blood Purif2012，34，1： | 1 |
| 17 | Determination of the enantiomeric composition of some molecules of pharmaceutical interest by chemometric analysis of the UV spectra of guest host complexes formed with modified cyclodextrins显示文摘 | Fakayode S O Swamidoss I M Busch M A | 2005 | Talanta2005，65，： | 1 |
| 18 | Advanced Glyca tion End Products and t32 Microglobulin as Predictors of Carpal Tunnel Syndrome in Hemodialysis Patients 显示文摘 | Busch M Schwenzky A Franke S | 2012 | Blood Purification2012，34，1： | 1 |
| 19 | Novel role of macrophage migration inhibitory factor in angiotensin II regulation of neuromodulation in rat brain显示文摘 | Busche S Gallinat S Fleegal M A | 2001 | Endocrinology2001，142，11： | 1 |
| 20 | Superior induction and maintenance of protective cd8 t ceils in mice infected with mouse cytomegalovirus vector expressing RAE-I'/显示文摘 | Trsan T Busche A Abram M | | Proc Natl Acad Sci U S A0，110，16： | 1 |
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