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| 1 | Testing for HCV Infection: An Update of Guidance for Clinicians and Laboratorians显示文摘 | Getchell Jane P Wroblewski Kelly E DeMaria Alfred Bean Christine L Parker Monica M Pandori Mark Dufour D Robert Busch Michael P Brecher Mark E Meyer William A Pesano Rick L Teo Chong-Gee Beckett Geoffrey A Araujo Aufra C Branson Bernard M D | 2013 | MMWR. Morbidity and Mortality Weekly Report2013，，18： | 3 |
| 2 | Emerging role of caldesmon in cancer:A potential biomarker for colorectal cancer and other cancers显示文摘Colorectal cancer(CRC) is a devastating disease, mainly because of metastasis. As a result, there is a need to better understand the molecular basis of invasion and metastasis and to identify new biomarkers and therapeutic targets to aid in managing these tumors. The actin cytoskeleton and actin-binding proteins are known to play an important role in the process of cancer metastasis because they control and execute essential steps in cell motility and contractility as well as cell division. Caldesmon(CaD) is an actin-binding protein encoded by the CALD1 gene as multiple transcripts that mainly encode two protein isoforms: High-molecular-weight CaD, expressed in smooth muscle, and low-molecular weight CaD(l-CaD), expressed in nonsmooth muscle cells. According to our comprehensive review of the literature, CaD, particularly l-CaD, plays a key role in the development, metastasis, and resistance to chemoradiotherapy in colorectal, breast, and urinary bladder cancers and gliomas, among other malignancies. CaD is involved in many aspects of the carcinogenic hallmarks, including epithelial mesenchymal transition via transforming growth factor-beta signaling, angiogenesis, resistance to hormonal therapy, and immune evasion. Recent data show that CaD is expressed in tumor cells as well as in stromal cells, such as cancerassociated fibroblasts, where it modulates the tumor microenvironment to favor the tumor. Interestingly, CaD undergoes selective tumor-specific splicing, and the resulting isoforms are generally not expressed in normal tissues, making these transcripts ideal targets for drug design. In this review, we will analyze these features of CaD with a focus on CRC and show how the currently available data qualify CaD as a potential candidate for targeted therapy in addition to its role in the diagnosis and prognosis of cancer. | Alya R Alnuaimi Vidhya A Nair Lara J Bou Malhab Eman Abu-Gharbieh Anu Vinod Ranade Gianfranco Pintus Mohamad Hamad Hauke Busch Jutta Kirfel Rifat Hamoudi Wael M Abdel-Rahman | 2022 | World Journal of Gastrointestinal Oncology2022，14，9： | 2 |
| 3 | WUSCHEL controls meristem function by direct regulation of cytokinin-inducible response regulators 显示文摘 | Leibfried A To JP Busch W | 2005 | Nature2005，438，7071： | 1 |
| 4 | CBM and CO2-ECBM related sorption processes in coal:A review显示文摘 | Busch A Gensterblum Y | 2011 | International Journal of Coal Geology2011，87，2： | 1 |
| 5 | Agenetic framework for floral patterning显示文摘 | Parcy F Nilsson O Busch M A Lee I Weigel D | 1998 | Nature1998，395，： | 1 |
| 6 | Transient tumor fibro blast interactions increase tumor cell malignancy by a TGF beta mediated mechanism in a mouse xenograft model of breast caneer显示文摘 | Stuehen CH Busch JI Tang B et a! | 2010 | PLoS One2010，5，3： | 1 |
| 7 | Hand-assisted laparoscopic splenectomy显示文摘 | Bemelman W A de Wit L T Busch O R | 2000 | Surg Endosc2000，14，11： | 1 |
| 8 | Long-term outcome and quality of life after thymectomy for myasthenia gravis显示文摘 | Busch C Machens A Pichlmeier U | 1996 | Ann Surg1996，224，2： | 1 |
| 9 | Regulatory elements of the floral homeotie gene AGAMOUS identified by phylogenetic footprinting and shadowing显示文摘 | HONG R L HAMAGUCHI L H BUSCH M A WEIGEL D | 2003 | The Plant Cell2003，15，： | 1 |
| 10 | Biochemical constrains limit the potential of the photochemical reflectance in- dex as a predictor of effective quantum efficiency of photosynthe- sis during the winter-spring transition in Jack pine seedlings 显示文摘 | Busch F Hunter N P A Ensminger I | 2009 | Functional Plant Biology2009，36，11： | 1 |
| 11 | Cardiomyocytes, endothelial ceils and car- diac fibroblasts: S100AI' s triple action in cardiovascular pathophysiology 显示文摘 | Rohde D Busch M Volkert A | 2015 | Future Cardio12015，11，3： | 1 |
| 12 | Complete genome sequence of Streptomyces lividans TK24显示文摘 | Rückert C Albersmeier A Busche T | 2015 | Journal of Biotechnology2015，199，1： | 1 |
| 13 | Methane and carbon dioxide adsorption-diffusion experiments on coal: upscaling and modeling显示文摘 | Busch A Gensterblum Y Krooss B M | 2004 | Coal Geology2004，，60： | 1 |
| 14 | Recent spectra of atmospheric turbulence显示文摘 | Busch N E Panofsky H A | 1968 | Quarterly Journal of the Royal Meteorological Society1968，94，： | 1 |
| 15 | Calcite textures, microtextures and rheological properties os marble mylonites in the Bancroft shear zone, Ontario, Canada显示文摘 | Busch J P Van der Pluijm B A | 1991 | J Struct Geol1991，17，： | 1 |
| 16 | IGF-1 and PDGF-bb suppress IL- 113-induced cartilage degradation through down-regulation of NF-lcB signaling: involvement of Src/PI-3K/AKT pathway 显示文摘 | Montaseri A Busch F Mobasheri A | 2011 | PLoS One2011，6，28： | 1 |
| 17 | Catheter-based radiofre- quency ablation therapy of the renal sympathetic nerve system for drug resistant hypertension in a patient with end-stage renal dis- ease显示文摘 | Prochnau D Lauten A Busch M | 2012 | Int J Cardiol2012，154，2： | 1 |
| 18 | Catheterbased radiofrequen- cy ablation therapy of the renal sympathetic-nerve system for drug resistant hypertension in a patient with end-stage renal disease 显示文摘 | Prochnau D Lauten A Busch M | 2012 | Int J Cardiol2012，154，2： | 1 |
| 19 | Development of a sensitive PCRinhibitong method to demonstrate HBV nucleic acid inactivation显示文摘 | Aytay A Ohagen A Busch Mr | 2004 | Transfusion2004，44，4： | 1 |
| 20 | IGF-1 and PDGF-bb suppress IL-1β-induced cartilage degradation through down-regulation of NF-κB signaling:involvement of Src/PI-3K/AKT pathway显示文摘 | MONTOSERI A BUSCH F MOBASHIERI A | 2011 | PLoS One2011，6，28： | 1 |
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