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| 1 | Research advances on the multiple uses of Moringa oleifera: a sustainable alternative for socially neglected population显示文摘Moringa oleifera Lam(Moringaceae) is a plant with high nutritional and medicinal value. Native to India, it is now widely distributed throughout tropical and subtropical regions of the world. Its different parts are sources of proteins, vitamins and minerals and present different pharmacological and biotechnological potential. Moreover, M. oleifera seeds are widely used in water and effluent treatment, for their coagulation, flocculation and sedimentation properties, their ability of improving water quality, by reducing organic matter and microbial load, with special applicability in intensive animal production systems, such as aquaculture. In addition, due to its high nutritional value and several medicinal properties, this tree may act as a nutritional and medical alternative for socially neglected populations. In this context, this review gathers information on M. oleifera, emphasizing its chemical constituents, nutritional, pharmacological and antimicrobial properties, applications in the treatment of water effluents, and ecological and social aspects. | Raimunda Samia Nogueira Brilhante Jamille Alencar Sales Vandbergue Santos Pereira Débora de Souza Collares Maia Castelo-Branco Rossana de Aguiar Cordeiro Célia Maria de Souza Sampaio Manoel de Araújo Neto Paiva Joao Bosco Feitosa dos Santos JoséJúlio CostaSidrim Marcos Fábio Gadelha Rocha | 2017 | Asian Pacific Journal of Tropical Medicine2017，10，7： | 10 |
| 2 | Bioconversion of D-xylose to xylitol by Debaryomyces hansenii UFV-170: product formation versus growth显示文摘 | Fa' bio C Sampaio Hila' rio C Mantovani Frederico Jo e' Vieira Passos | 2005 | Process Biochemistry2005，40，： | 1 |
| 3 | Destination attributes’ evaluation, satisfaction and behavioural intentions: A structural modelling approach 显示文摘 | Eusébio C Vieira A L | 2013 | International Journal of Tourism Research2013，15，1： | 1 |
| 4 | Respiratory Symptoms and lung function impairment in underground gold miners in ghana 显示文摘 | Bio F Sadhra S Jackson C | 2007 | Ghana Med J2007，41，2： | 1 |
| 5 | How does glutamine synthetase activity determine plant tolerance to ammonium显示文摘 | Cruz C Bio AFM Dominguez-Valdivia MD | | 0，，5： | 1 |
| 6 | Evaluation of the efficacy of triple therapy regimen for Helicobacter pylori eradication in gastrectomized patients with gastric adenocarcinoma显示文摘 | Jose Luiz Bertoli Neto Laercio Gomes Louren?o Cícero Fernando Bertoli Fábio Samsonowski Ulbrich Antoninho Ricardo Sabbi Alexandre Galv?o Bueno | 2006 | Gastric Cancer2006，，4： | 1 |
| 7 | hafluence of temperature and pH on xylitol production from xylose by Debaryomyces hansenii UFV-170 显示文摘 | Fa' bio C Sampaio Ce' lia Alencar de Moraes Danilo De Faveri el al | 2006 | Process Biochemistry2006，41，： | 1 |
| 8 | Forced vital capacity in patients with idiopathic pulmonary fibrosis: test properties and minimal clinically important difference显示文摘 | Du Bios R M Weycker D Albera C | 2011 | Am J Respir Crit Care Med2011，184，12： | 1 |
| 9 | Calibration and validation of FAO-AquaCrop model to estimate the total biomass and yacon root yield显示文摘Due to the current water scarcity in the world,it is extremely important to improve the use of this natural and exhaustible resource in agriculture,by contributing to increase agricultural production and sustainability.Several models of crop growth simulation were developed to predict the edaphoclimatic effects on crop yield.These models are calibrated and validated for a given region using the data generated from field experiments.Therefore,the objective of this study was to calibrate and validate the FAO AquaCrop model for yacon(Smallanthus sonchifolius)crop in a tropical climate.The experiment was conducted in an experimental area located in the municipality of Ibatiba,state of Espírito Santo(Brazil)during the years of 2013 and 2014.The calibration was done using the Autumn planting and validation with the Winter and Spring plantings.For the statistical analysis,the coefficient of determination,Willmott concordance index,bias for the systematic error,root mean square error and the mean absolute error to test the model performance were used.In general,the FAO AquaCrop model predicted the root yield,total biomass and harvest index with acceptable accuracy,and with deviations of less than 6%for total and root biomass.Late planting of yacon showed a reduction in yield as well as total biomass. | Ramon Amaro de Sales Alexandre Cândido Xavier Evandro Chaves de Oliveira Fábio Luiz de Oliveira Diego Mathias Natal da Silva Sávio da Silva Berilli | 2020 | International Journal of Agricultural and Biological Engineering2020，13，3： | 1 |
| 10 | Osmotin purified from the latex of Calotropis procera : Biochemical characterization, biological activity and role in plant defense显示文摘 | Cleverson Diniz Teixeira de Freitas Fábio César Sousa Nogueira Ilka Maria Vasconcelos José Tadeu Abreu Oliveira Gilberto Barbosa Domont Márcio Viana Ramos | 2011 | Plant Physiology and Biochemistry2011，，7： | 1 |
| 11 | Two-stage anaerobic membrane bioreactor for the treatment of sugarcane vinasse:assessment on biological activity and filtration performance显示文摘 | TAINá MOTA Vera SANTOS Fábio S AMARAL Míriam C S | 2013 | Bioresource Technology2013，146，： | 1 |
| 12 | 血浆和(或)酵母提取物对7-63日龄仔猪生长性能和肠道形态的影响显示文摘研究旨在评估在7~63日龄仔猪日粮中添加血浆和(或)酵母提取物对仔猪日增质量、日采食量和饲料转化率及肠道形态的影响。试验采用288头体质量为(2.57±0.05)kg的7日龄仔猪,按照日粮差别随机分为4组,每组6个重复,每重复12头仔猪。试验预备期I(7~21日龄)、预备期II(22—35日龄)及第1阶段(36~49日龄)各组日粮为对照组(CD组),不添加血浆或酵母提取物;血浆组(PL组),添加6%、4%和2%血浆;酵母提取物组(YE组),添加6%、4%和2%酵母提取物;血浆+酵母提取物组(PL+YE组),血浆和酵母提取物分别添加3%、2%和1%。第1I阶段(50—63日龄)所有仔猪饲喂相同的饲料。7~21和7~28日龄没有观察到生长性能的差别,但是第7天一第35天PL+YE组的日增质量有优势(CD、PL、YE和PL+YE组的日增质量分别为268、278、271和288g)。观察7~49及7~63日龄发现,PL+YE组仔猪的日增质量(分别为330和519g)和日采食量(分别为307和647g)都比CD组的日增质量(分别为295和486g)和日采食量(分别为266和594g)要高。不同组间的肠道形态没有显著差异(P〉0.05)。试验结果表明,血浆和酵母提取物提高7~63日龄的仔猪日增质量,但是没有影响到仔猪的肠道形态。 | Leandro César Milagres Rigueira Maria Cristina Thomaz Dalton César Milagres Rigueira Leonardo Augusto Fonseca Pascoal Alessandro Borges Amorim Fábio Enrique Lemos Budio 周小辉 骆明霞 严书林 | 2014 | 饲料研究2014，37，9： | 1 |
| 13 | Meplazumab in hospitalized adults with severe COVID-19(DEFLECT):a multicenter,seamless phase 2/3,randomized,third-party double-blind clinical trial显示文摘Meplazumab,a humanized CD147 antibody,has shown favourable safety and efficacy in our previous clinical studies.In DEFLECT(NCT04586153),167 patients with severe COVID-19 were enroled and randomized to receive three dosages of meplazumab and a placebo.Meplazumab at 0.12 mg/kg,compared to the placebo group,showed clinical benefits in significantly reducing mortality by 83.6%(2.4%vs.14.6%,p=0.0150),increasing the proportion of patients alive and discharged without supplemental oxygen(82.9%vs.70.7%,p=0.0337)and increasing the proportion of patients who achieved sustained clinical improvement(41.5%vs.31.7%).The response rate in the 0.2 mg/kg group was relatively increased by 16.0%compared with the placebo group(53.7%vs.46.3%).Meplazumab also reduced the viral loads and multiple cytokine levels.Compare with the placebo group,the 0.3 mg/kg significantly increased the virus negative rate by 40.6%(p=0.0363)and reduced IL-8 level(p=0.0460);the 0.2 mg/kg increased the negative conversion rate by 36.9%,and reduced IL-4(p=0.0365)and IL-8 levels(p=0.0484).In this study,the adverse events occurred at a comparable rate across the four groups,with no unexpected safety findings observed.In conclusion,meplazumab promoted COVID-19 convalescence and reduced mortality,viral load,and cytokine levels in severe COVID-19 population with good safety profile. | Huijie Bian Liang Chen Zhao-Hui Zheng Xiu-Xuan Sun Jie-Jie Geng Ruo Chen Ke Wang Xu Yang Shi-Rui Chen Si-Yu Chen Rong-Hua Xie Kui Zhang Jin-Lin Miao Jun-Feng Jia Hao Tang Shuang-Shuang Liu Hong-Wei Shi Yong Yang Xiao-Chun Chen Vinay Malhotra Nosheen Nasir Iffat Khanum Faisal Mahmood Saeed Hamid Claudio Marcel Berdun Stadnik Kengi Itinose Caroline Cândida Carvalho de Oliveira Cesar Dusilek Lucas Rivabem Adilson Joaquim Westheimer Cavalcante Suzara Souto Lopes Wladmir Faustino Saporito Fábio JoséConcilio Fucci Jesus Abraham Simon-Campos Ling Wang Lin-Na Liu Qing-Yi Wang Ding Wei Zheng Zhang Zhi-Nan Chen Ping Zhu | 2023 | Signal Transduction and Targeted Therapy2023，8，2： | 1 |
| 14 | Respiratory symptoms and lung function impairment in underground gold miners in Ghana显示文摘 | Bio FY Sadhra S Jackson C | 2007 | Ghana medical journal2007，41，2： | 1 |
| 15 | How does glutamine synthetase activity determine plant tolerance to ammonium? 显示文摘 | Cruz C Bio A F M Dominguez-Valdivia M D | 2006 | Planta2006，223，： | 1 |
| 16 | Comparisons of finite element J and KJ estimation scheme predictions for a surface cracked pipe under bending or tension 显示文摘 | Gilles Ph Bios C | 1996 | Fatigue and Fracture American Society of Mechanical Engineers Pressure Vessels and Piping Division (Publication) PVP ASME New York USA1996，323，1： | 1 |
| 17 | Update on the pharmacologic management of neonatal abstinence syndrome 显示文摘 | Bio L L Siu A Poon C Y | 2011 | J Perina-tol2011，31，11： | 1 |
| 18 | Feelings of loss in parents of children with infantile cerebral palsy显示文摘 | Ferndndez-Aledntara M Garcia-Caro M P Laynez-Ru- bio C | 2015 | Disabil Health J2015，8，1： | 1 |
| 19 | How does glutamine synthctase activity determine plant toleranee to ammonium显示文摘 | Cruz C Bio A F Dominguez-Valdivia M D | 2005 | Planta2005，10，： | 1 |
| 20 | Evaluation of sample preparation protocols for proteomic analysis of sunflower leaves显示文摘 | Marcelo Anselmo Oseas da Silva Jerusa Simone Garcia Gustavo Henrique Martins Ferreira de Souza Marcos Nogueira Eberlin Fábio César Gozzo Marco Aurélio Zezzi Arruda | 2009 | Talanta2009，，4： | 1 |
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