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| 1 | Effectiveness of Acupuncture on Pain, Physical Function and Health-Related Quality of Life in Patients with Rheumatoid Arthritis: A Systematic Review of Quantitative Evidence显示文摘Objective: To identify and synthesize the most recent available evidence of effectiveness of acupuncture on pain, physical function and health-related quality of life(HRQoL) in patients with rheumatoid arthritis(RA). Methods: A comprehensive search of 12 Western and Chinese databases was undertaken from their inception up to end of 2016. Randomized controlled trials(RCTs), concerning patients with RA treated with needle acupuncture, written in English, Portuguese, German or Chinese were included. Primary outcomes included pain, physical function and HRQoL. Secondary outcomes included morning stiffness, functional impairment, number of tender and swollen joints and serum concentrations of inflamatory markers. Methodological quality was assessed by three independent reviewers using the standardized critical appraisal instrument from the Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instrument. Results: Twenty-two studies met the inclusion criteria. Of those, 9 studies were excluded after assessment of their methodological quality. The remaining 13 original RCTs included 974 patients. Ten of these studies published in China, showed favorable statistical significant effects of acupuncture in relieving symptoms of RA compared with controls. Conclusions: Evidence suggests that acupuncture interventions may have a positive effect in pain relief, physical function and HRQo L in RA patients. However, due to the heterogeneity and methodologic limitations of the studies included in this systematic review, evidence is not strong enough to produce a best practice guideline. | Susana Seca Diana Miranda Daniela Cardoso Bernice Nogueira Henry J.Greten Antonio Cabrita Manuel Alves Rodrigues | 2019 | Chinese Journal of Integrative Medicine2019，25，9： | 11 |
| 2 | Community-based lifestyle modification programme for non-alcoholic fatty liver disease: A randomized controlled trial显示文摘 | Vincent Wai-Sun Wong Ruth Suk-Mei Chan Grace Lai-Hung Wong Bernice Ho-Ki Cheung Winnie Chiu-Wing Chu David Ka-Wai Yeung Angel Mei-Ling Chim Jennifer Wing-Yan Lai Liz Sin Li Mandy Man-Mei Sea Francis Ka-Leung Chan Joseph Jao-Yiu Sung Jean Woo Henry Lik-Yue | 2013 | Journal of Hepatology2013，，3： | 2 |
| 3 | Effect of vitamin E and human placenta cysteine peptidase inhibitor on expression of cathepsins B and L in implanted hepatoma Morris 5123 tumor model in Wistar rats显示文摘AIM: To examine the effectiveness of human placental inhibitors, by injecting vitamin E to rats with transplanted Norris-5123 hepatoma, on the expression of cathepsins B and L in tumor, liver, lung and blood sera after transplantation of Norris 5123 hepatoma.METHODS: Animals were divided into 10 groups receiving three different concentrations of vitamin E and inhibitors along or in combination and compared with negative control (healthy rats) and positive control (tumor rats). Effectiveness of treatment was evaluated with regard to survival time,tumor response and determination of the activities of proteolytic enzymes and their inhibitors using flurogenic substrates.RESULTS: Cathepsins B and L activities were elevated by 16-fold in comparison with negative control tissues, and their endogenous inhibitor activity decreased by 1.2-fold before treatment. In several cases, tumors completely disappeared following vitamin E plus human placental cyteine protease inhibitor (CPI) compared with controls.The number of complete tumor responses was higher when 20 m/kg vitamin E plus 400 μg of CPI was used, i.e.7/10 rats survived more than two mo. Cathepsins B and L were expressed significantly in tumor, liver, lung tissues and sera in parallel to the increasing of the endogenous inhibitor activity compared with the controls after treatment (P<0.0001).CONCLUSION: The data indicate formation of metastasis significantly reduced in treated rats, which might provide a therapeutic basis for anti-cancer therapy. | Tadeusz Sebzda Piotr Hanczyc Yousif Saleh Bernice F Akinpelumi Maciej Siewinski Jerzy Rudnicki | 2005 | World Journal of Gastroenterology2005，11，4： | 2 |
| 4 | Management of esophageal caustic injury显示文摘Ingestion of caustic substances and its long-term effect on the gastrointestinal system maintain its place as an important public health issue in spite of the multiple efforts to educate the public and contain its growing number. This is due to the ready availability of caustic agents and the loose regulatory control on its production. Substances with extremes of pH are very corrosive and can create severe injury in the upper gastrointestinal tract. The severity of injury depends on several aspects: Concentration of the substance, amount ingested, length of time of tissue contact, and p H of the agent. Solid materials easily adhere to the mouth and pharynx, causing greatest damage to these regions while liquids pass through the mouth and pharynx more quickly consequently producing its maximum damage in the esophagus and stomach. Esophagogastroduodenoscopy is therefore a highly recommended diagnostic tool in the evaluation of caustic injury. It is considered the cornerstone not only in the diagnosis but also in the prognostication and guide to management of caustic ingestions. The degree of esophageal injury at endoscopy is a predictor of systemic complication and death with a 9-fold increase in morbidity and mortality for every increased injury grade. Because of this high rate of complication, prompt evaluation cannot be overemphasized in order to halt development and prevent progression of complications. | Mark Anthony A De Lusong Aeden Bernice G Timbol Danny Joseph S Tuazon | 2017 | World Journal of Gastrointestinal Pharmacology and Therapeutics2017，8，2： | 2 |
| 5 | Student anxiety and depression:Comparison of questionnaire and interview assessments显示文摘 | Bernice Andrews Jennie Hejdenberg John Wilding | | 0，，： | 1 |
| 6 | The Effect of Progressive, Reinforcing Telephone Education and Counseling Versus Brief Educational Intervention on Knowledge, Self-Care Behaviors and Heart Failure Symptoms显示文摘 | David W. Baker Darren A. DeWalt Dean Schillinger Victoria Hawk Bernice Ruo Kirsten Bibbins-Domingo Morris Weinberger Aurelia Macabasco-O’Connell Kathy L. Grady George M. Holmes Brian Erman Kimberly A. Broucksou Michael Pignone | 2011 | Journal of Cardiac Failure2011，，10： | 1 |
| 7 | Depressive symptoms and health-related quality of life显示文摘 | Bernice R John S Mark A | 2003 | JAMA2003，290，2： | 1 |
| 8 | Relationships Between First and Second Language Phonological Processing Skills and Reading in Chinese-Engish Speakers living in English-Speaking Contexts显示文摘 | GOTTARDOA A PENNY CHIAPPEB BERNICE YANC | | 0，，： | 1 |
| 9 | Agnathia- otocephaly complex: a case report and examination of the OTX2 显示文摘 | Sean Herman Maria Delio Bernice Morrow | 2012 | Gene2012，494，1： | 1 |
| 10 | Auditory P3 a deficits in male subjects at high risk for alcoholism显示文摘 | Michio H Bernice P David B | 2001 | Biol Psychiatry2001，49，： | 1 |
| 11 | Semantic friendly indexing and querying of images based on the extraction of the objective semantic cues显示文摘 | Mojsilovic Aleksandra Gomes Jose Rogowitz Bernice | 2004 | The International Journal of Computer Vision2004，56，12： | 1 |
| 12 | ERP componentsin category matching tasks 显示文摘 | Ji Jun Porjesz Bernice Begleiter Henri | 1998 | Electroencephalography andClinical Neurophysiology1998，108，4： | 1 |
| 13 | Auditory P3 a deficits in male subjects at high risk for alcoholism显示文摘 | Michio H Bernice P David B | 2001 | Biol Psychiatry2001，49，： | 1 |
| 14 | Expert Perspectives on Western European Prison Health Services: Do Ageing Prisoners Receive Equivalent Care?显示文摘 | Wiebke Bretschneider Bernice Simone Elger | 2014 | Journal of Bioethical Inquiry2014，，3： | 1 |
| 15 | Alcoholism is a disinhibitory disorder: neurophysiological evidence from a Go/No-Go task 显示文摘 | CHELLA K BERNICE P KEVIN A J | 2005 | Biological Psychology2005，69，3： | 1 |
| 16 | Visual object priming differs from visual word priming an ERP study显示文摘 | Zhang Xiaolei Begleiter Henri Porjesz Bernice | 1997 | Electroencephalography and Clinical Neurophysiology1997，102，3： | 1 |
| 17 | Event related potentials during object recognition tasks 显示文摘 | ZHANG X L HENRI B BERNICE P | 1995 | Brain Research Bulletin1995，38，6： | 1 |
| 18 | Distribution of a viscous binder during high shear granulation—Sensitivity to the method of delivery and its impact on product properties显示文摘 | Bernice Mei Jin Tan Zhi Hui Loh Josephine Lay Peng Soh Celine Valeria Liew Paul Wan Sia Heng | 2013 | International Journal of Pharmaceutics2013，，： | 1 |
| 19 | C/T polymorphism in the 5′untranslated region of the apolipoprotein(a) gene introduces an upstream ATG and reduces in vitro translation显示文摘 | Bernice R Zysow Gisela E | 1995 | Arteriosclerosis Thrombosis and Vascular Biology1995，15，： | 1 |
| 20 | C/T Polymorphism in the 5' Untranslated Region of the Apolipoprotein(a) Gene Introduces an Upstream ATG and Reduces In Vitro Translation显示文摘 | Zysow Gisela E | 1995 | Arteriosclerosis Thrombosis and Vascular Biology1995，15，： | 1 |
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