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| 1 | 儿童功能性胃肠病罗马Ⅳ标准显示文摘罗马标准是目前关于功能性胃肠病( FGID)分类最全面且不断更新的标准。罗马Ⅰ、Ⅱ标准分别于1994年、1999年发布。罗马Ⅱ标准开始单列儿童FGID分类。2006年,根据年龄不同,婴幼儿(0-36个月)和儿童(〉36个月) FGID的罗马Ⅲ诊断标准发布,但相关的流行病学、病理生理学、诊断检查、治疗策略以及预后等资料都很少。 | Marc A. Benninga Samuel Nurko Christophe Faure Paul E. Hyman Ian St. James Roberts Neil L. Schechter Jeffrey S. Hyams Carlo Di Lorenzo Miguel Saps Robert J. Shulman Annamaria Staiano Miranda van Tilburg | 2017 | 中华儿科杂志2017，55，1： | 108 |
| 2 | Childhood constipation as an emerging public health problem显示文摘Functional constipation(FC) is a significant health problem in children and contrary to common belief, has serious ramifications on the lives of children and their families. It is defined by the Rome criteria which encourage the use of multiple clinical features for diagnosis. FC in children has a high prevalence(0.7%-29%) worldwide, both in developed and developing countries. Biopsychosocial risk factors such as psychological stress, poor dietary habits, obesity and child maltreatment are commonly identified predisposing factors for FC. FC poses a significant healthcare burden on the already overstretched health budgets of many countries in terms of out-patient care, in-patient care, expenditure for investigations and prescriptions. Complications are common and range from minor psychological disturbances, to lower health-related quality of life. FC in children also has a significant impact on families. Many paediatric clinical trials have poor methodological quality, and drugs proved to be useful in adults, are not effective in relieving symptoms in children. A significant proportion of inadequately treated children have similar symptoms as adults. These factors show that constipation is an increasing public health problem across the world with a significant medical, social and economic impact. This article highlights the potential public health impact of FC and the possibility of overcoming this problem by concentrating on modifiable risk factors rather than expending resources on high cost investigations and therapeutic modalities. | Shaman Rajindrajith Niranga Manjuri Devanarayana Bonaventure Jayasiri Crispus Perera Marc Alexander Benninga | 2016 | World Journal of Gastroenterology2016，22，30： | 10 |
| 3 | Epidemiology of constipation in children and adults: A systematic review显示文摘 | Suzanne M. Mugie Marc A. Benninga Carlo Di Lorenzo | 2010 | Best Practice & Research Clinical Gastroenterology2010，，1： | 4 |
| 4 | Childhood Functional Gastrointestinal Disorders: Neonate/Toddler显示文摘 | Paul E. Hyman Peter J. Milla Marc A. Benninga Geoff P. Davidson David F. Fleisher Jan Taminiau | 2006 | Gastroenterology2006，，5： | 3 |
| 5 | Evaluation and Treatment of Functional Constipation in Infants and Children: Evidence-Based Recommendations From ESPGHAN and NASPGHAN显示文摘 | M.M. Tabbers C. DiLorenzo M.Y. Berger C. Faure M.W. Langendam S. Nurko A. Staiano Y. Vandenplas M.A. Benninga | 2014 | Journal of Pediatric Gastroenterology and Nutrition2014，，： | 2 |
| 6 | Probiotics for childhood functional gastrointestinal disorders: a systematic review and meta‐analysis显示文摘 | Judith J Korterink Lize Ockeloen Marc A Benninga Merit M Tabbers Mirrian Hilbink Judith M Deckers‐Kocken | 2014 | Acta Paediatr2014，，4： | 2 |
| 7 | Functional Defecation Disorders in Children: Comparing the Rome II with the Rome III Criteria显示文摘 | Rosa Burgers Alon D. Levin Carlo Di Lorenzo Marcel G.W. Dijkgraaf Marc A. Benninga | 2012 | The Journal of Pediatrics2012，，4： | 2 |
| 8 | Value-at-Risk(VaR)显示文摘 | Benninga S Wiener Z | 1998 | Mathematica in Education and Research1998，7，4： | 1 |
| 9 | Epidemiologyof constipation in children and adults: a systematic review 显示文摘 | Mugie S M Benninga M A Di Lorenzo C | 2011 | Best Pract Res Clin Gastroenterol2011，25，1： | 1 |
| 10 | Characterization of anorectal pressure and the anorectal inhibitory reflex in healthy preterm and term infants显示文摘 | Benninga MA Omari TI Haslam RR | | 0，，02： | 1 |
| 11 | Use of Rome II criteria in childhood defecation disorders: Applicability in clinical and research practice显示文摘 | Wieger P. Voskuijl Jarom Heijmans Hugo S.A. Heijmans Jan A.J.M. Taminiau Marc A. Benninga | 2004 | The Journal of Pediatrics2004，，2： | 1 |
| 12 | Is There an Association between Functional Constipation and Excessive Bodyweight in Children?显示文摘 | Ilan J.N. Koppen Carlos A. Velasco-Benítez Marc A. Benninga Carlo Di Lorenzo Miguel Saps | 2015 | The Journal of Pediatrics2015，，： | 1 |
| 13 | Constipation in child- hood 显示文摘 | Mugie SM Di Lorenzo C Benninga MA | 2011 | Net Rev Gastroenterol2011，8，9： | 1 |
| 14 | Emerging therapies for GERD 显示文摘 | Vander-Pol R Benninga M A Smout A J | 2011 | J Pediatr Gastroenterol Nutr2011，53，2： | 1 |
| 15 | Childhood functional gastrointestinal disorders:neonate/toddler显示文摘 | Hyman P E Milla P J Benninga M A | 2006 | Gastroenterology2006，130，5： | 1 |
| 16 | Quality of life is impaired in children with functional defecation disorders 显示文摘 | Benninga MA | 2006 | J Pediatr2006，82，6： | 1 |
| 17 | Epidemiology of consti- pation in children and adults: a systematic review 显示文摘 | Mugie SM Benninga MA Di Lorenzo C | 2011 | Best Pract Res Clin Gastroenterol2011，25，1： | 1 |
| 18 | Functional constipa- tion in children :a systematic review on prognosis and predictive factors显示文摘 | Pijpers MA Bongers ME Benninga MA | 2010 | J Pediatr Gastroenterol Nutr2010，50，3： | 1 |
| 19 | Epidemiology of con- stipation in children and adults: a systematic review 显示文摘 | Mugie SM Benninga MA Di Lorenzo C | 2011 | Best Practice and Research in Clinical Gastr-nterology2011，，01： | 1 |
| 20 | Paediatric and adult colonic manometry: A tool to help unravel the pathophysiology of constipation显示文摘Colonic motility subserves large bowel functions, including absorption, storage, propulsion and defaecation. Co-lonic motor dysfunction remains the leading hypothesis to explain symptom generation in chronic constipation, a heterogeneous condition which is extremely prevalent in the general population, and has huge socioeconomic impact and individual suffering. Physiological testing plays a crucial role in patient management, as it is now accepted that symptom-based assessment, although im-portant, is unsatisfactory as the sole means of directing therapy. Colonic manometry provides a direct method for studying motor activities of the large bowel, and this review provides a contemporary understanding of how this technique has enhanced our knowledge of normalcolonic motor physiology, as well as helping to elucidate pathophysiological mechanisms underlying constipation. Methodological approaches, including available catheter types, placement technique and recording protocols, are covered, along with a detailed description of re-corded colonic motor activities. This review also criti-cally examines the role of colonic manometry in current clinical practice, and how manometric assessment may aid diagnosis, classification and guide therapeutic inter-vention in the constipated individual. Most importantly, this review considers both adult and paediatric patients. Limitations of the procedure and a look to the future are also addressed. | Philip G Dinning Marc A Benninga Bridget R Southwell S Mark Scott | 2010 | World Journal of Gastroenterology2010，16，41： | 1 |
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