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| 1 | 儿童功能性胃肠病罗马Ⅳ标准显示文摘罗马标准是目前关于功能性胃肠病( FGID)分类最全面且不断更新的标准。罗马Ⅰ、Ⅱ标准分别于1994年、1999年发布。罗马Ⅱ标准开始单列儿童FGID分类。2006年,根据年龄不同,婴幼儿(0-36个月)和儿童(〉36个月) FGID的罗马Ⅲ诊断标准发布,但相关的流行病学、病理生理学、诊断检查、治疗策略以及预后等资料都很少。 | Marc A. Benninga Samuel Nurko Christophe Faure Paul E. Hyman Ian St. James Roberts Neil L. Schechter Jeffrey S. Hyams Carlo Di Lorenzo Miguel Saps Robert J. Shulman Annamaria Staiano Miranda van Tilburg | 2017 | 中华儿科杂志2017，55，1： | 108 |
| 2 | 光激酶C基因突变导致的大头精子畸形是阿尔及利亚男性不育症的最常见遗传因素显示文摘克氏综合征和Y染色体微缺失是过去针对男性不育症仅有的两项基因检测分析技术。北非男性经常出现两种罕见的畸形精子症:大头和圆头精子畸形,推荐进行AURKC和DPYl9L2基因检测。对阿尔及利亚男性不育患者进行以上基因检测,评估两种畸形精子症的患病率,并与克氏综合征和Y染色体微缺失的频率进行比较。我们对阿尔及利亚君士坦丁市的IbnRochd医院辅助生殖中心进行不育症咨询的599名患者进行了回顾性研究,其中404人存在精液参数异常现象。14人和7人分别患有典型的大头精子畸形或圆头精子畸形,进而对这些患者进行了AURKC和DPYl9L2基因分析显示,11名大头精子畸形患者存在4URKC基因突变(79%),相当于所有精液异常人群的2.7%。而5名圆头精子畸形患者,相当于1.2%的不育症患者,均存在DPYl9L2基因缺失。通过比较,我们预测该人群中克氏综合症和Y染色体微缺失的患病率分别是1.6%和0.23%。我们的研究表明AURKC基因突变较克氏综合症更常见,它是导致北非男性不育的主要遗传因素。此外,本文也预测了AURKC和DP"觋2基因缺陷发生率分别是Y染色体微缺失发生率的10倍和5倍。 | Leyla Ounis Abdelali Zoghmar Charles Coutton Leila Rouabah Maroua Hachemil Delphine Martinez Guillaume Martinez Ines Bellil Douadi Khelifi Christophe Arnoult Julien Faure Sebti Benbouhedja Abdelkader Rouabah Pierre F Ray | 2015 | Asian Journal of Andrology2015，17，1： | 5 |
| 3 | Body mass index is not associated with sperm-zona pellucida binding ability in subfertile males显示文摘生活方式因素,可以影响男富饶例如重量和营养的地位,包括精子授精能力。这回顾的研究的目的是评估在身体团索引(BMI ) 和根据带绑定(ZB ) 估计的精子带 pellucida 绑定能力之间的协会测试,它被描述了是为预言的一个相关诊断工具在 vitro 授精(IVF ) 能力。从与主要自发或温和的男因素不孕诊断的夫妇的 306 个男病人被包括。在根据 ZB,测试索引的 BMI 和精液参数之间的关联被估计,和越过 BMI 范畴的阳性、否定的测试的频率。在这张选择人口, BMI 不与根据精子的能力估计绑在带 pellucida 的常规精液参数或精子质量有关。在男肥胖的情况下的 IVF 过程的以前描述的差的结果能由于另外的精子缺点,例如精子 capacitation 或 acrosome 反应的改变。在男 BMI 和生物结果之间的连接例如授精率,应该进一步在 IVF 过程期间被评估。 | Nathalie Sermondade Charlotte Dupont Celine Faure Marouane Boubaya Isabelle Cedrin-Durnerin Pascale Chavatte-Palmer Christophe Sifer Rachel Levy | 2013 | Asian Journal of Andrology2013，15，5： | 4 |
| 4 | Solid,non-skin,post-liver transplant tumors:Key role oflifestyle and immunosuppression management显示文摘Liver transplantation has been the treatment of choice for end-stage liver disease since 1983.Cancer has emerged as a major long-term cause of death for liver transplant recipients.Many retrospective studies that have explored standardized incidence ratio have reported increased rates of solid organ cancers postliver transplantation;some have also studied risk factors.Liver transplantation results in a two to five-fold mean increase in the rate of solid organ cancers.Risk of head and neck,lung,esophageal,cervical cancers and Kaposi’s sarcoma is high,but risk of colorectal cancer is not clearly demonstrated.There appears to be no excess risk of developing breast or prostate cancer.Environmental risk factors such as viral infection and tobacco consumption,and personal risk factors such as obesity play a key role,but recent data also implicate the role of calcineurin inhibitors,whose cumulative and dose-dependent effects on cell metabolism might play a direct role in oncogenesis.In this paper,we review the results of studies assessing the incidence of non-skin solid tumors in order to understand the mechanisms underlying solid cancers in post-liver transplant patients and,ultimately,discuss how to prevent these cancers.Immunosuppressive protocol changes,including a calcineurin inhibitor-free regimen,combined with dietary guidelines and smoking cessation,are theoretically the best preventive measures. | Christophe Carenco Stéphanie Faure JoséUrsic-Bedoya Astrid Herrero Georges Philippe Pageaux | 2016 | World Journal of Gastroenterology2016，22，1： | 2 |
| 5 | Fractalkine/CX3CL1 production by human aortic smooth muscle cells impairs monocyte procoagulant and inflammatory responses显示文摘 | Véronique Ollivier Sophie Faure Nadine Tarantino Sylvie Chollet-Martin Philippe Deterre Christophe Combadière Dominique de Prost | 2003 | Cytokine2003，，6： | 1 |
| 6 | Functional Gastrointestinal Disorders: Working Group Report of the First World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition显示文摘 | Jeffrey Hyams Richard Colletti Christophe Faure Elizabeth Gabriel-Martinez Helga Verena L. Maffei Mauro B. Morais Quak Seng Hock Yvan Vandenplas | 2002 | Journal of Pediatric Gastroenterology and Nutrition2002，，： | 1 |
| 7 | Duration of adrenal inhibition following a?single dose of etomidate in critically ill patients显示文摘 | Marc Vinclair Christophe Broux Patrice Faure Julien Brun Céline Genty Claude Jacquot Olivier Chabre Jean-Fran?ois Payen | 2008 | Intensive Care Medicine2008，，4： | 1 |
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