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| 1 | DISC1 genetics, biology and psychiatric illness显示文摘精神病学的混乱是高度可继承的,并且在许多,个人们多半从基因和环境的联合效果产生。向是影响的基因之一精神分裂症,双极的混乱和消沉冒险的 DISC1 的证据点的实质的身体,和 DISC1 的功能的研究因而有潜力关于导致主要精神病的小径揭示大部分。这里,我们考察 DISC1 在发展和成年大脑在多重批评小径之上通过效果影响疾病风险的证据。 | Pippa A. THOMSON Elise L.V. MALAVASI Ellen GRüNEWALD Dinesh C. SOARES Malgorzata BORKOWSKA J. Kirsty MILLA | 2013 | Frontiers in Biology2013，8，1： | 5 |
| 2 | Pupal emergence pattern in cactophilic Drosophila and the effect of host plants显示文摘Drosophila buzzatii and D.koepferae are sibling cactophilie species.The former breeds primarily on prickly pears (genus Opuntia)whereas the latter breeds on columnar cacti of the genera Cereus and Trichocereus,although with certain degree of niche overlapping.We examined the interspecific differences in diurnal temporal patterns of adult emergence from puparia and evaluated whether this behavior is affected by rearing in the different cactus hosts available in nature.We detected important host-dependent genetic variation for this trait differentially affecting the emergence schedule of these species.Diumal pattern of emergence time was directly correlated with developmental time and negatively correlated with adult wing size,suggesting that early emergences are at least indirectly correlated with increased fitness.We discussed our results in terms of their putative effects on fitness and the genetic-metabolic pathways that would be presumably affected by host's nutritional-chemical differences. | Eduardo M.Soto Julián Padrò Pablo Milla Carmona Diego T.Tuero Valeria P.Carreira Ignacio M.Soto | 2018 | Insect Science2018，25，6： | 3 |
| 3 | Childhood Functional Gastrointestinal Disorders: Neonate/Toddler显示文摘 | Paul E. Hyman Peter J. Milla Marc A. Benninga Geoff P. Davidson David F. Fleisher Jan Taminiau | 2006 | Gastroenterology2006，，5： | 3 |
| 4 | Characterization, passive and active treatment in strabismic amblyopia: a narrative review显示文摘Strabismic amblyopia is characterized by a distorted spatial perception.In this condition,the neurofunctional disorder occurring during first years of life provoke several monocular and binocular anomalies such as crowding,deficits in the accommodative response,contrast sensitivity,and ocular motility abilities.The inhibition of the binocular function of the brain by the misaligned amblyopic eye induces a binocular imbalance leading to interocular suppression and the reduction or lack of stereoacuity.Passive treatments such as occlusion,optical and/or pharmacological penalization,and Bangerter foils has been demonstrated to be potentially useful treatments for strabismic amblyopia.Recent researches have proved new pharmacological options to improve and maintain visual acuity af ter occlusion treatment in strabismic amblyopia.Likewise,the active vision therapy,in the last years,is becoming a very relevant therapeutic option in combination with passive treatments,especially during and after monocular therapy,in the attempt of recovering the imbalanced binocular vision. | Myriam Milla David P.Pinero | 2020 | International Journal of Ophthalmology(English edition)2020，13，7： | 3 |
| 5 | Shoot-level biomass allocation is affected by shoot type in Fagus sylvatica显示文摘Aims The present study aims(i)to examine if recently reported interspecific shoot-level biomass allocational trade-offs,i.e.isometric trade-offs between leaf mass(LM)and stem mass(SM)and between leaf size and leaf number,hold intraspecifically and(ii)to explore whether those scaling relationships are independent of shoot type(i.e.long vs.short shoots).Methods In order to address our questions,we used Fagus sylvatica saplings growing under a broad light range that were sampled in theWestern Carpathians Mountains(Slovakia).Important Findings We found that:(i)intraspecific shoot-level biomass allocational trade-offs differ from those reported interspecifically and that(ii)long and short shoots differ in biomass allocation scaling coefficients.Allometric relationships with slopes statistically smaller than 1.0 or higher than -1.0,were found between SM and LM and between mean leafing intensity and individual leaf mass,respectively,in long shoots.In contrast,isometric scaling was found in short shoots.This suggests that leaf mass in short shoots is unaffected by shoot stem mass,in contrast to long shoots.Short shoots also had a larger fraction of biomass allocated to leaves.Beech shoots,as has been observed in other shoot dimorphic species,are specialized,with short shoots specializing in carbon gain and long shoots in space acquisition.A greater shift in LM than in SM among species during speciation shifting from allometric intraspecific relationships to an isometric interspecific scaling relationship between those traits could explain the discrepancies between the outputs of the present intraspecific study and others similar studies.This study draws attention to the importance of considering shoot types in future studies dealing with allocation rules in species with dimorphic shoots. | Benjamín Jarcuska Ruben Milla | 2012 | Journal of Plant Ecology2012，5，4： | 2 |
| 6 | Cloning of a disintegrin metalloprote-inase that processes precursor tumour-necrosis factoralpha显示文摘 | Moss ML Jin SL Milla ME | | 0，，： | 2 |
| 7 | A Practical Guide for the Diagnosis of Primary Enteric Nervous System Disorders显示文摘 | M.G. Sch?ppi A. Staiano P.J. Milla V.V. Smith J.A. Dias R. Heuschkel S. Husby M.L. Mearin A. Papadopoulou F.M. Ruemmele Yvan Vandenplas S. Koletzko | 2013 | Journal of Pediatric Gastroenterology and Nutrition2013，，5： | 2 |
| 8 | Systematic review with meta‐analysis: the declining risk of colorectal cancer in ulcerative colitis显示文摘 | C. Casta?o‐Milla M. Chaparro J. P. Gisbert | 2014 | Aliment Pharmacol Ther2014，，7： | 2 |
| 9 | Alzheimer病与脑缺血的相互作用聚焦炎症显示文摘进行性记忆障碍、与局部炎症相关的β-淀粉样蛋白(β-amyloid,Aβ)斑块、神经原纤维缠结和选择性脑区神经元脱失是Alzheimer病(Alzheimer’s disease,AD)的特征。虽然β-淀粉样前体蛋白(β-amyloid precursor protein,APP)和Aβ在AD的病因学中起关键作用,但究竟何种形式的APP或Aβ与AD脑内的神经元易损性有关仍不清楚。最近已经公认,作为老年人痴呆的另一种病因,脑缺血促进了AD的发病,而认知功能严重减退的患者和潜在的AD患者发生脑缺血事件的风险增高。此外,载脂蛋白E(apolipoprotein E,ApoE)ε4等位基因既是AD的危险因素,也是脑缺血和脑出血后转归不良的危险因素。最近已经报道了AD模型中降低神经元死亡阈值的一些因素和分子机制,在这些神经炎症中似乎起着重要的作用。在中枢神经系统中,AD神经病理学和缺血性损伤的发展和成熟均以神经胶质细胞活化和炎症介质上调为特征。业已证实,抗炎症策略对体内AD样神经病理学和缺血性损伤的预防和治疗的确有益。本文对提示人APP在神经元的过度表达促使脑更易遭受缺血性损伤的一些研究结果进行了总结,并对增强神经元对缺血性卒中易感性的一些因素做了介绍。 | Milla Koistinaho Jari Koistinaho 郑莹 袁宝玉 闫福岭 | 2006 | 国际脑血管病杂志2006，14，11： | 2 |
| 10 | A phase Ⅱ trial of cisplatin and vinorelbine in patients with recurrent or metastatic squamous cell carcinoma of the head and neck显示文摘 | Espinosa E Zamora P Milla A | 2002 | Head Neck2002，24，12： | 1 |
| 11 | Cloning of a disintegrin metalloproteinase that processes precursor tumour necrosis factor-alpha 显示文摘 | Moss ML Jin SL Milla ME | 1997 | Nature1997，385，6618： | 1 |
| 12 | Should perioperative supplemental oxygen be routinely recommended for surgery patients:a Bayesian meta-analysis显示文摘 | Kao LS Millas SG Pedroza C | 2012 | Ann Surg2012，256，6： | 1 |
| 13 | Increased levels of acute-phase serum proteins in diabetes显示文摘 | | 1989 | Metabolism1989，38，： | 1 |
| 14 | Managing Knowledge and Knowledge competences in projects and project organizations显示文摘 | Kasvi J J Jyrki Vartiainen Matti Hailikari Milla | 2003 | International Journal of Project Management2003，21，： | 1 |
| 15 | A practical guide for the diagnosis o{ primary Enteric nervous system disorders显示文摘 | Sch~ippi MG Staiano A Milla PJ | 2013 | J Pediatr Gastroenterol Nutr2013，57，5： | 1 |
| 16 | Hepatolithiasis and cholan- giocarcinoma in cystic fibrosis: a case series and review of the literature 显示文摘 | Perdue DG Cass OW Milla C | 2007 | Dig Dis Sei2007，52，10： | 1 |
| 17 | Wide and/or short cleft palate显示文摘 | Millaed DR | 1962 | Plast Reconstr Surg1962，29，： | 1 |
| 18 | Epicardial beating heart cryoablation using a novel argon-based cryoclamp and linear probe显示文摘 | Milla F Skubas N Briggs WM | 2006 | J Thorac Cardiovasc Surg2006，131，2： | 1 |
| 19 | Glutathione peroxidase genes in Arobidopsis are ubiquitous and regulated by abiolic stresses through diverse signalling paths 显示文摘 | Miguel Milla R Maurer A | 2003 | The Plant Journal2003，36，： | 1 |
| 20 | Managing knowledge and knowledge competences in projects and project organizations显示文摘 | Kasvi J J Jyrki Vartiainen Matti Hailikari Milla | 2003 | International Journal of Project Management2003，21，： | 1 |
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