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| 1 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 2 | Oral Candida in HIV infection and AIDS: new perspectives/new approaches显示文摘 | Coleman DC Bennett DE Sullivan DJ | 1993 | Crit Rev Microbiol1993，19，： | 1 |
| 3 | Human melanocyte senescence and melanoma susceptibility genes显示文摘 | Bennett DC | 2003 | Oncogene2003，22，20： | 1 |
| 4 | 2013 ACC/ AHA Guideline on the Assessment of Cardiovascular Risk: A Re- port of the American College of Cardiology/American Heart Associ- ation Task Force on Practice Guidelines 显示文摘 | Goff DC Jr Lloyd - Jones DM Bennett G | 2013 | Circulation2013，8，4： | 1 |
| 5 | Protein tyrosine kinases in malignant melanoma显示文摘 | Easy DJ Bennett DC | | 0，，05： | 1 |
| 6 | Identification of the albino mutation of mouse tyrosinase by analysis of an in vitro revertant 显示文摘 | Jackson IJ Bennett DC | 1990 | Pro-ceedings of the national academy of sciences of USA1990，87，1： | 1 |
| 7 | Balance training improves function and postural control in those with chronic ankle instability显示文摘 | McKcon PO Ingersoll CD Kerrigan DC Saliba E Bennett BC Hertel J | 2008 | Med Sci Sports Exerc2008，1040，10： | 1 |
| 8 | An association of fibromyalgia with primary Sjogren' s syndrome:a prospective study of 72 patients显示文摘 | Bonafede RP Downey DC Bennett RM | 1995 | J Rheumatol1995，22，1： | 1 |
| 9 | Abnormal pigmentation in hypomela- nosis of rto and pigmentary mosaicism : the role of pigmentary genes 显示文摘 | Taibjee SM Bennett DC Moss C | 2004 | Br J Dermatol2004，151，2： | 1 |
| 10 | 2013 ACC/AHA guideline on the assessment of cardiovascular risk:a report of the American College of Cardiology/American Heart Association task force on practice guidelines显示文摘 | Goff DC Jr Lloyd-Jones DM Bennett G | 2014 | J Am Coll Cardiol2014，63，25： | 1 |
| 11 | Protein tyrosine kinases in malignant melanoma 显示文摘 | Easty DJ Bennett DC | 2000 | Melanoma Res2000，10，5： | 1 |
| 12 | 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines 显示文摘 | Goff Jr DC Lloyd-Jones DM Bennett G | 2014 | Circulation2014，129，： | 1 |
| 13 | Down-regulation of the c-myc proto-oncogene in inhibition of vascular smooth-muscle cell proliferation:a signal for growth arrest显示文摘 | Littlewood TD Hancock DC | 1994 | Biochem J1994，302，： | 1 |
| 14 | Comprehensive association analy- sis of candidate genes for generalized vitiligo supports XBP1, FOXP3, and TSLP显示文摘 | Birlea SA Jin Y Bennett DC | 2011 | J Invest Dermatol2011，131，2： | 1 |
| 15 | Clonal separation of mature melanocytes from premelanocytes in a diploid human cell strain:spontaneous and induced pigmentation of premelanocytes显示文摘 | Bennett DC Bridges K Mckay I | 1985 | J Cell Sci1985，77，6： | 1 |
| 16 | The color loci of miee-a genetic century 显示文摘 | Bennett DC Lamoreux ML | 2003 | Pigment Cell Res2003，16，4： | 1 |
| 17 | Tyrosinase stabilization by Tyrpl ( the brown locus protein) 显示文摘 | Kobayashi T Imokawa G Bennett DC | 1998 | JBC1998，273，31： | 1 |
| 18 | Novel vitiligo susceptibility loci on chromosomes ( AIS2 ) and $ ( AIS3 ), confirmation of SLEV 1 on chromosome 17 and their roles in an autoimmune diathesis显示文摘 | Sprita RA Gowan K Bennett DC | 2004 | Am J Hum Genet2004，74，1： | 1 |
| 19 | Human melanocyte senescence and melanoma susceptibility genes显示文摘 | Bennett DC | 2003 | Oncogene2003，22，： | 1 |
| 20 | Artifi- cial dermis as an alternative for coverage of complex scalp defects following excision of malignant tumors 显示文摘 | Komorowska-Timek E Gabriel A Bennett DC | 2005 | Plast Re- eonstr Surg2005，115，： | 1 |
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