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2118篇 您的检索式:作者名="Becker R"
    题名 作者 年代 出处 被引量
1异源nifA基因对苜蓿中华根瘤菌nifA突变体的互补分析显示文摘为深入研究苜蓿中华根瘤菌NifA的特性,分别用组成型表达的慢生型大豆根瘤菌和紫云英根瘤菌的nifA基因互补苜蓿中华根瘤菌nifA突变体,观察其共生表型.结果表明,慢生型大豆根瘤菌和紫云英根瘤菌nifA基因不能互补苜蓿中华根瘤菌nifA突变体的共生表型.以苜蓿中华根瘤菌nifA突变体为遗传背景,利用全基因组微阵列实验比较分析引入异源nifA基因后产生的基因表达谱的变化.结果显示,苜蓿中华根瘤菌自身NifA蛋白引起238个基因的表达发生变化.这些表达差异的基因分属共生、能量和中心代谢、持家、细胞结构与运输等生物学功能组.慢生型大豆根瘤菌、紫云英根瘤菌和阴沟肠杆菌的NifA蛋白分别引起了20,7和9个基因的表达发生变化.这些基因主要是固氮相关基因,但差异不及苜蓿中华根瘤菌NifA互补菌明显.以苜蓿中华根瘤菌nifH启动子与lacZ融合基因为报道基因,研究nifH的表达.结果指出,慢生型大豆根瘤菌和紫云英根瘤菌的NifA蛋白只能部分激活苜蓿中华根瘤菌nifH的表达,激活水平分别为苜蓿中华根瘤菌NifA蛋白激活率的70%和50%,与微阵列实验结果相符.姚振华 田哲贤 戴小密 Anke Becker 李健 严海芹 肖琰 朱家璧 俞冠翘 Silvia Rüberg 王忆平 邹华松 2006科学通报2006,51,19:4
2Neoadjuvant chemotherapy with cisplatin, 5-FU, and leucovorin (PLF) in locally advanced gastric cancer: a prospective phase II study显示文摘Katja Ott Andreas Sendler Karen Becker Hans-Joachim Dittler Hermann Helmberger Raimonde Busch Christian Kollmannsberger J. Rüdiger Siewert Ulrich Fink 2003Gastric Cancer2003,,3:3
3nifA突变的苜蓿根瘤菌在根瘤中的转录组学分析显示文摘用全基因组微阵列比较了根瘤中苜蓿根瘤菌1021的nifA突变菌和野生菌的基因表达谱.分析结果表明,nifA的缺失引起601个基因的表达发生变化.这些基因分别属于生物大分子的合成代谢、三羧酸循环及呼吸代谢以及结瘤固氮过程等多个功能组,预示着根瘤中细菌的生长状态发生了显著的变化.在根瘤中,fixK以及受其激活的基因在nifA突变菌中的表达量显著高于野生菌.定量实时PCR分析表明,根瘤中fixLJ的转录水平在nifA突变菌中显著高于野生菌.通过统计学方法从13个表达发生显著变化的基因的上游调控序列中找到推测的NifA结合位点.田哲贤 邹华松 李健 张远涛 刘影 俞冠翘 朱家璧 Silvia Rüberg Anke Becker 王忆平 2006科学通报2006,51,15:3
4Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial显示文摘Claus R?del Torsten Liersch Heinz Becker Rainer Fietkau Werner Hohenberger Torsten Hothorn Ullrich Graeven Dirk Arnold Marga Lang-Welzenbach Hans-Rudolf Raab Heiko Sülberg Christian Wittekind Sergej Potapov Ludger Staib Clemens Hess Karin Weigang-K?hler G 2012Lancet Oncology2012,,7:2
5The cost of hospitalization in Crohn’s disease显示文摘Russell D Cohen Leanne R Larson Joel M Roth Russell V Becker Lisa L Mummert 2000The American Journal of Gastroenterology2000,,2:2
6Preoperative versus postoperative chemoradiotherapy for rectal Cancer显示文摘Sauer R Becker H Hohenberger W New England Journal of Medicine0,,:2
7Primary prevention of ischemic stroke: A statement for healthcaro professionals from the Stroke Council of American Heart Association显示文摘Goldstein LB Adams R Becker K 2001Stroke2001,32,1:1
8The potential to deposit good quality thin films atrelatively mater显示文摘BECKER R S ZHENG Tan ELTON J 1986Sol Energy Mater1986,13,:1
9Preoperative versus postoperative chemoradiotherapy for rectal cancer显示文摘Sauer R Becker H Hohenberger W 2004N Engl J Med2004,351,17:1
10Risperidone,but not olanzapine,decreases bone mineral density in female premenopausal schizophrenia patients显示文摘 Liver O Mester R 2003J Clin Psychiatry2003,64,7:1
11Evidence from ultra-high pressure marbles for recycling of sediments into the mantle显示文摘 Altherr R 1992Nature1992,358,74:1
12New isocyanates from amino acids 显示文摘HETTRICH W BECKER R 1997Polymer1997,38,10:1
13Post- traumatic stress disorder symptoms following media exposure to tragic events: Impact of 9/11 on children at risk for anxiety disorders显示文摘Otto M W Henin A Hirshfeld- Becker D R 2007Journal of Anxiety Disorders2007,21,7:1
14Oscillatory Motions Sunspots 显示文摘Beckers J M Schuhz R B 1972Solar Physics1972,27,1:1
15Comparison of pretherapeutic and posttherapeutic expression levels of Chemotherapy-Associated genes in adenocarcinomas of the esophagus treated by 5-Fluorouracil - and Cisplatin- Based neoadjuvant chemotherapy 显示文摘Langer R Specht K Becker K 2007Am J Clin Pathol2007,28,2:1
16Impact event at the Permian-Triassic boundary:Evidence from extraterrestrial noble gases in fullerenes显示文摘Becker L Poreda R J Hunt A G 2001Science2001,291,:1
17CT of coronary artery disease显示文摘SCHOEPF U J BECKER C R OHNESORGE B M 2004Radiology2004,23,1:1
18显示文摘Timothy A Becker Daryl R Kipke 2002Journal of Biomedical Materials Research2002,61,4:1
19Fertility Choice in a Model of Economic Growth 显示文摘Barro R J Becker G S 1989Econometric1989,2,:1
20Inhibition of human brain and RBC acetylcholinesterase (ACHE) by heptylphysostigmine (HPTL)显示文摘Moriearty P L Becker R E 1992Methods Find Exp Clin Pharmacol1992,14,8:1
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