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389篇 您的检索式:作者名="Beamer"
    题名 作者 年代 出处 被引量
1Characterization of the Expression of the ATP-Gated P2X7 Receptor Following Status Epilepticus and during Epilepsy Using a P2X7-EGFP Reporter Mouse显示文摘Mounting evidence suggests that the ATP-gated P2X7 receptor contributes to increased hyperexcitability in the brain.While increased expression of P2X7 in the hippocampus and cortex following status epilepticus and during epilepsy has been repeatedly demonstrated,the cell type-specific expression of P2X7 and its expression in extra-hippocampal brain structures remains incompletely explored.In this study,P2X7 expression was visualized by using a transgenic mouse model overexpressing P2X7 fused to the fluorescent protein EGFP.The results showed increased P2X7-EGFP expression after status epilepticus induced by intra-amygdala kainic acid and during epilepsy in different brain regions including the hippocampus,cortex,striatum,thalamus and cerebellum,and this was most evident in microglia and oligodendrocytes.Colocalization of P2X7-EGFP with cell type-specific markers was not detected in neurons or astrocytes.These data suggest that P2X7 activation is a common pathological hallmark across different brain structures,possibly contributing to brain inflammation and neurodegeneration following acute seizures and during epilepsy.James Morgan Mariana Alves Giorgia Conte Aida Menendez-Mendez Laura de Diego-Garcia Gioacchino de Leo Edward Beamer Jonathon Smith Annette Nicke Tobias Engel 2020Neuroscience Bulletin2020,36,11:3
2Extraction and characterisation of lipids from Antarctic krill ( Euphausia superba )显示文摘Joseph C. Gigliotti Matthew P. Davenport Sarah K. Beamer Janet C. Tou J. Jaczynski 2010Food Chemistry2010,,3:2
3Association of the Pro12Ala variant in the peroxisome proliferator activated receptor γ gene with obesity in two Caucasian populations显示文摘Beamer B Yen C Andersen R 1998Diabetes1998,47,:2
4Chronic blood hyperviscosity in subjects with acute stroke,transient ischemic attack,and risk factor for stroke显示文摘Coull BM Beamer NB de Garmo P 1991Stroke1991,22,:1
5GHRH receptor of little mice contains a missense mutation in the extraceL lular domain that disrupts receptor function显示文摘Godfrey P Rahal J O Beamer W G 1993Nat Genet1993,4,:1
6Nutritional composi- tion of novel nutraceufical egg products developed with omega-3 rich oils显示文摘KASSIS N BEAMER S K MATAK K E 2010LWT- Food Science and Technology2010,43,8:1
7Interlerleukin- 6 and interleukim- 1 receptor antagonist in acute stroke显示文摘Beamer NB Coull BM Clark WM 1995Ann Neurol1995,37,6:1
8Fibrinogen and the albumin-globulin ratio in recurrent stroke显示文摘Beamer N Coull BM Sexton G 1993Stroke1993,24,:1
9C-reactive protein is associated with sleep disordered breathing independent of adiposity显示文摘Punjabi NM Beamer BA 2007Sleep2007,30,:1
10Critical role of MARCO in crystalline silica-induced pulmonary inflammation 显示文摘Thakur SA Beamer CA Migliaccio CT 2009Toxicol Sci2009,108,2:1
11Development of nutraceutical egg products with omega-3-rich oils显示文摘KASSIS N DRAKE S R BEAMER S K 2010LWT-Food Sci- ence and Technology2010,43,5:1
12Genetic variability in adult bone density among inbred strains of mice显示文摘Beamer WG Donahue LR Rosen CJ 0,,05:1
13Ogilvie syndrome as a postoperative complication 显示文摘Tenofsky PL Beamer L Smith RS 2000Arch-Surg2000,135,6:1
14Extrac- tion and characterisation of lipids from Antarctic krill ( Euphausia superba) 显示文摘GIGLIOTTI J C DAVENPORT M P BEAMER S K 2011Food Chemistry2011,125,3:1
15Endosteal strut augment reduces complications associated with proximal humeral locking plates显示文摘Neviaser AS Hettrich CM Beamer BS 0,,12:1
16Locked plating of the proximal humerus using an endosteal implant 显示文摘Hettrieh CM Neviaser A Beamer BS 2012Orthop Trauma2012,26,4:1
17Alterations in glucose disposal in sleep - disordered breathinng 显示文摘Punjabi NM Beamer BA 2009Respir Crit Care Med2009,179,3:1
18Critical role ofMARCO in crystalline silica-induced pulmonary inflammation 显示文摘Thakur S A Beamer C A Migliaccio C T 2009Toxicol Sci2009,108,2:1
19Interleukin-10 promotes Mycobacterium tuberculosis disease progression in CBA/J mice显示文摘Beamer G Flaherty DB Stromberg P 2008J Immunol2008,181,8:1
20in diabetic caucasians: Identification of a P12A PPARγ2 Missense Mutation 显示文摘Yen CJ Beamer BA Negri C Molecular scanning of the human peroxisome proliferator activated receptorγ gene 8 1997Biochem Biophys Res Commun1997,241,:1
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