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1188篇 您的检索式：作者名="Andersen R"

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	题名	作者	年代	出处	被引量
1	Impaired contractility and remodeling of the upper gastrointestinal tract in diabetes mellitus type-1显示文摘AIM: To investigate that both the neuronal function of the contractile system and structural apparatus of the gastrointestinal tract are affected in patients with longstanding diabetes and auto mic neuropathy. METHODS: The evoked esophageal and duodenal contractile activity to standardized bag distension was assessed using a specialized ultrasound-based probe. Twelve type-1 diabetic patients with autonomic neuropathy and severe gastrointestinal symptoms and 12 healthy controls were studied. The geometry and biomechanical parameters (strain, tension/stress, and stiffness) were assessed. RESULTS: The diabetic patients had increased frequency of distension-induced contractions (6.0 ± 0.6 vs 3.3 ± 0.5, P < 0.001). This increased reactivity was correlated with the duration of the disease (P = 0.009). Impaired coordination of the contractile activity in diabetic patients was demonstrated as imbalance between the time required to evoke the first contraction at the distension site and proximal to it (1.5 ± 0.6 vs 0.5 ± 0.1, P = 0.03). The esophageal wall and especially the mucosa-submucosa layer had increased thickness in the patients (P < 0.001), and the longitudinal and radial compressive stretch was less in diabetics (P <0.001). The esophageal and duodenal wall stiffness and circumferential deformation induced by the distensions were not affected in the patients (all P > 0.14). CONCLUSION: The impaired contractile activity with an imbalance in the distension-induced contractions likely reflects neuronal abnormalities due to autonomic neuropathy. However, structural changes and remodeling of the gastrointestinal tract are also evident and may add to the neuronal changes. This may contribute to the pathophysiology of diabetic gut dysfunction and impact on future management of diabetic patients with gastrointestinal symptoms.	Jens BrΦndum FrΦkjΦr SΦren Due Andersen Niels EjskjΦr Peter Funch-Jensen AsbjΦrn Mohr Drewes Hans Gregersen	2007	World Journal of Gastroenterology2007，13，36：	8
2	Association of the Pro12Ala variant in the peroxisome proliferator activated receptor γ gene with obesity in two Caucasian populations显示文摘	Beamer B Yen C Andersen R	1998	Diabetes1998，47，：	2
3	Viability Thresholds of Ischemic Penumbra of Hyperacute Stroke Defined by Perfusion-Weighted MRI and Apparent Diffusion Coefficient显示文摘	L. R?hl L. ?stergaard C.Z. Simonsen P. Vestergaard-Poulsen G. Andersen M. Sakoh D. Le Bihan C. Gyldensted	2001	Stroke: Journal of the American Heart Association2001，，5：	2
4	Phylogenetic analysis of 32 strains of Vaucheria (Xanthophyceae) using the rbcL gene and ITS two flanking space regions显示文摘	Andersen R A Bailey J C	2002	J Phycol2002，38，：	1
5	Serotonin transporter mRNA levels are associated with the methylation of an upstream CpG Island显示文摘	Philibert R Madan A Andersen A	2007	Am J Medical Genetics Part B2007，144，1：	1
6	Topologies for VSC transmission显示文摘	Andersen B R Xu L Horton P J	2002	Power Engineering Journal2002，16，3：	1
7	VSC transmission operating under unbalanced AC conditions-analysis and control design显示文摘	Xu L Andersen B R Cartwright P	2005	IEEE Trans on Power Delivery2005，20，1：	1
8	Hydraulic and chemical signals in the control of leaf expansion and stomatal conductance in soybean exposedto drought stress显示文摘	Liu F Jensen C R Andersen M N	2003	Functional Plant Biol2003，30，1：	1
9	Functional markers in plants 显示文摘	Andersen J R Liibberstedt T	2003	Trends in Plant Science2003，8，：	1
10	The structural relation betweenprecipitates in Al-Mg-Si alloys显示文摘	ANDERSEN S J MARIOARA C D VISSERS R FROSETH A ZANDBERGEN H W	2007	Materials Science andEngineering A2007，444，：	1
11	Age-related de- clines in car following performance under simulated fog conditions显示文摘	Ni R Kang J J Andersen G J	2010	Accident Analysis and Preven- tion2010，42，3：	1
12	Molecular dynamics simulations of a supercooled monatomic liquid and glass显示文摘	Fox J R Andersen H C		0，，18：	1
13	Randomised trial of endoscopic endoprosthesis versus operative bypass in malig- nant obstructive jaundice 显示文摘	Andersen J R Sorensen S M Kruse A	1989	Gut1989，30，8：	1
14	Diet effects onintrinsic rate of increase and rearing of Proprioseiopsis asetus(Acari:Phytoseiidae)显示文摘	Emmert C J Mizell R F Andersen P C	2008	Annals of the Entomological Societyof America2008，101，6：	1
15	Cox's regression model for counting processes: a large sample study显示文摘	Andersen P K Gill R D	1982	Annals of Statistics1982，10，：	1
16	Imagery of Denmark among Visitors to Danish Fine Arts Exhibitions in Scotland显示文摘	Andersen R Prentice Guerin S	1997	Tourism Management1997，，18：	1
17	Iron accumulation in the striatum predicts aging - related decline in motor function in rhesus monkeys显示文摘	Cass WA Grondin R Andersen AH	2007	Neurobiol Aging2007，28，2：	1
18	显示文摘	Karinen R Andersen JM Ripel A	2009	Journal of Analytical Toxicology2009，33，7：	1
19	Topologies for VSC transmission显示文摘	Andersen B R Xu L Horton P J	2002	Power Engineering Journal2002，21，4：	1
20	Ants as bioindicator of habitat disturbance:validation of the functional group model for Australia's humid tropics显示文摘	King J R Andersen A N Cutter A D	1998	Biodiversity and Conservation1998，7，：	1

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