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| 1 | Relationship between the severity of hepatitis C virus-related liver disease and the presence of Helicobacter species in the liver: A prospective study显示文摘AIM: To determine the presence of Helicobacter species DNA in the liver of chronic hepatitis C (CHC) patients with and without cirrhosis as compared to controls, and to identify the bacterial species involved. METHODS: Seventy-nine consecutive patients (HBV and HIV negative) with a liver sample obtained after liver biopsy or hepatic resection were studied: 41 with CHC without cirrhosis, 12 with CHC and cirrhosis, and 26 controls (HCV negative). Polymerase chain reactions (PCRs) targeting Helicobacter 16S rDNA and species- specific were performed on DNA extracted from the liver. A gastric infection with H pylori was determined by serology and confirmed by 13C-urea breath test. RESULTS: Overall, Helicobacter 16S rDNA was found in 16 patients (20.2%). Although positive cases tended to be higher in CHC patients with cirrhosis (41.6%) than in those without cirrhosis (17.0%) or in controls (15.4%), the difference was not statistically significant (P =0.08). H pylori-like DNA was identified in 12 cases and H. pullorum DNA in 2, while 2 cases remained unidenti- fied. Gastric infection with H pylori was found in only 2 of these patients. CONCLUSION: Our results do not confirm the associ- ation of Helicobacter species DNA in the liver of CHC patients with advanced liver disease. The lack of correlation between positive H pylori serology and the presence of H pylori-like DNA in the liver may indicate the presence of a variant of this species. | Laurent Castéra Anne Pedeboscq Marcia Rocha Brigitte Le Bail Corinne Asencio Victor de Lédinghen Pierre-Henri Bernard Christophe Laurent Marie-Edith Lafon Maylis Capdepont Patrice Couzigou Paulette Bioulac-Sage Charles Balabaud FrancisMégraud Armelle Ménard | 2006 | World Journal of Gastroenterology2006，12，45： | 3 |
| 2 | Results of treatment of sep- tic knee arthritis:A retrospective series of 40 cases显示文摘 | Balabaud L Gaudias J Boeri C | 2007 | Knee Surg Sports Traumatol Arthrose2007，15，4： | 1 |
| 3 | Results of treatment of septic knee arthritis: a retrospective series of 40 eases 显示文摘 | Balabaud L Gaudias J Boeri C | 2007 | Knee Surg Sports Trau -- matol Arthrose2007，15，4： | 1 |
| 4 | Results of treat- ment of septic knee arthrltis: a retrospective series of 40 cases 显示文摘 | Balabaud L Gaudias J Boeri C | 2007 | Knee Surg Sports Traumatol Arthrosc2007，15，4： | 1 |
| 5 | Results of treatment of septic knee arthritis : a retrospective series of 40 cases显示文摘 | Balabaud L Gaudias J Boeri C | 2007 | Knee Surg Sports Traumatol Arthrosc2007，15，： | 1 |
| 6 | Cervical and thoracic spine tumor management : surgical indications, techniques, and outcomes 显示文摘 | Mazel C Balabaud L Bennis S | 2009 | Or- thop Clin North Am2009，40，1： | 1 |
| 7 | Biomechanical evaluation of a bipedicular spinal fixation system : a com- parative stiffness test 显示文摘 | Balabaud L Gallard E Skalli W | 2002 | Spine2002，27，17： | 1 |
| 8 | MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations 显示文摘 | Ladeiro Y Couchy G Balabaud C Bioulac-Sage P Pelletier L Rebouissou S | 2008 | Hepatology2008，47，： | 1 |
| 9 | Cervical and thoracic spine tumor management : surgical indications, techniques, and outcomes显示文摘 | Mazel C Balabaud L Bennis S | 2009 | Orthop Clin North Am2009，40，1： | 1 |
| 10 | Biomechanical evaluation of a bipedicular spine fixation device: three different strength tests 显示文摘 | Balabaud L Gallard E Skalli W | 2003 | Eur Spine J2003，12，5： | 1 |
| 11 | Repair of distal biceps tendon ruptures using a suture anchor and an anterior approach显示文摘 | Balabaud L Ruiz C Nonnenmacher J | | 0，，： | 1 |
| 12 | Detection of nodules in liver cirrhosis: spiral computed tomography or magnetic resonance imaging? A prospective study of 88 nodules in 34 patients显示文摘 | Victor de Lédinghen David Laharie Robin Lecesne Brigitte Le Bail Maria Winnock Pierre-Henri Bernard Jean Saric Patrice Couzigou Charles Balabaud Paulette Bioulac-Sage Jacques Drouillard | 2002 | European Journal of Gastroenterology & Hepatology2002，，2： | 1 |
| 13 | Clinical, Morphologic, and Molecular Features Defining So-Called Telangiectatic Focal Nodular Hyperplasias of the Liver显示文摘 | Paulette Bioulac-Sage Sandra Rebouissou Antonio Sa Cunha Emmanuelle Jeannot Sébastien Lepreux Jean-Frédéric Blanc Hélène Blanché Brigitte le Bail Jean Saric Pierre Laurent-Puig Charles Balabaud Jessica Zucman-Rossi | 2005 | Gastroenterology2005，，5： | 1 |
| 14 | Direct evidence that hepatocyte growth factor-induced invasion of hepatocellular carcinoma cells is mediated by urokinase显示文摘 | Arnaud Monvoisin Véronique Neaud Victor De Lédinghen Liliane Dubuisson Charles Balabaud Paulette Bioulac-Sage Alexis Desmoulière Jean Rosenbaum | 1999 | Journal of Hepatology1999，，3： | 1 |
| 15 | Results oftreatmentment of septic knee arthritis:a retros pectiveseries of 40 cases 显示文摘 | Balabaud L Gaudias J Boeri C | 2007 | Knee surg sports trauma tol Arthrosc2007，，： | 1 |
| 16 | Cervical and thoracic spine tumor management : surgical indications, techniques, and outcomes显示文摘 | Mazel C Balabaud L Bennis S | 2009 | Orthop Clin North Am2009，40，1： | 1 |
| 17 | Results of treatment of septic knee arthritis :A retrospective se- ries of 40 cases 显示文摘 | Balabaud L Gaudias J Boeri C | 2007 | Knee Surg Sports Traumatol Arthrosc2007，15，4： | 1 |
| 18 | Cervical and thoracic spine tumor management:surgical indications,techniques,and outcomes显示文摘 | Mazel C Balabaud L Bennis S | 2009 | Orthop Clin North Am2009，40，1： | 1 |
| 19 | Cervical and thoracic spine tumor management: surgical indications, techniques, and outcomes显示文摘 | Mazel C Balabaud L Bennis S | 2009 | Orthop Clin North Am2009，40，1： | 1 |
| 20 | Cervical and thoracic spine tumor management:surgical indications,techniques,and out-comes显示文摘 | Mazel C Balabaud L Bennis S | | 0，，01： | 1 |
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