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| 1 | 肝细胞腺瘤相关的基因型-表现型:新的分类及与HCC的关系显示文摘Hepatocellular adenomas are benign tumors that can be difficult to diagnose.To refine their classification,we performed a comprehensive analysis of their genetic,pathological,and clinical features.A multicentric series of 96 liver tumors with a firm or possible diagnosis of hepatocellular adenoma was reviewed by liver pathologists.In all cases,the genes coding for hepatocyte nuclear factor 1α(HNF1α)and β-catenin were sequenced.No tumors were mutated in both HNF1αand β-catenin enabling tumors to be classified into 3 groups,according to genotype.Tumors with HNF1αmutations formed the most important group of adenomas(44 cases).They were phenotypically characterized by marked steatosis(P < 10-4),lack of cytological abnormalities(P < 10-6),and no inflammatory infiltrates(P < 10-4).In contrast,the group of tumors defined by β-catenin activation included 13 lesions with frequent cytological abnormalities and pseudo-glandular formation(P < 10-5).The third group of tumors without mutation was divided into two subgroups based on the presence of inflammatory infiltrates.The subgroup of tumors consisting of 17 inflammatory lesions,resembled telangiectatic focal nodular hyperplasias,with frequent cytological abnormalities(P = 10-3),ductular reaction(P < 10-2),and dystrophic vessels(P =.02).In this classification,hepatocellular carcinoma associated with adenoma or borderline lesions between carcinoma and adenoma is found in 46%of the β-catenin-mutated tumors whereas they are never observed in inflammatory lesions and are rarely found in HNF1αmutated tumors(P =.004).In conclusion,the molecular and pathological classification of hepatocellular adenomas permits the identification of strong genotype-phenotype correlations and suggests that adenomas with β-catenin activation have a higher risk of malignant transformation. | Zucman-Rossi J. Jeannot E. Van Nhieu J.T. 陈云茹 | 2006 | 世界核心医学期刊文摘(胃肠病学分册)2006，2，9： | 2 |
| 2 | Mass Transfer Characteristics of Solvent Extraction into a Single Drop at the Tip of a Syringe Needle显示文摘 | Jeannot M A Cantwell F F | 1997 | Anal Chem1997，69，： | 2 |
| 3 | Adsorption and desorption phenomena on thermally annealed multi-walled carbon nanotubes by XANES study显示文摘The multi-walled carbon nanotubes(MWCNTs) studied in this work were synthesized by the catalytic chemical vapor deposition(CCVD) process, and were thermally annealed by the hot filament plasma enhanced(HF PE) method at 550℃ for two hours.The x-ray absorption near edge structure(XANES) technique was used to investigate the adsorption and desorption phenomena of the MWCNTs at normal and grazing incidence angles.The adsorbates were found to have different sensitivities to the thermal annealing.The geometry of the incident beam consistently gave information about the adsorption and desorption phenomena.In addition, the adsorption of non-intrinsic potassium quantitatively affected the intrinsic adsorbates and contributed to increase the conductivity of the MWCNTs.The desorption of potassium was almost 70% greater after the thermal annealing.The potassium non-intrinsic adsorbates are from a physisorption mechanism whereas the intrinsic adsorbates result from chemisorption. | Camile Rodolphe Tchenguem Kamto Bridinette Thiodjio Sendja Jeannot Mane Mane | 2019 | Chinese Physics B2019，28，9： | 2 |
| 4 | Determination of oxanilic and sulfonic acid metabolites of acetochlor in soils by liquid chromatographyelectrospray ionization mass spectrometry显示文摘 | Dagnac T Jeannot R Mouvet C | 2002 | Journal of Chromatography A2002，957，： | 1 |
| 5 | Physical and Chemical Properties of Metal Oxide Additions to Ag-SnO2 Contact Materials and Predictions of Electrical Performance显示文摘 | Pinard J Ramoni P | 1994 | IEEE Trans on CPMT-Part A1994，17，1： | 1 |
| 6 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ effluxpump显示文摘 | Jeannot K Elsen S Khler T | | 0，，： | 1 |
| 7 | Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the Mex- CD-OprJ efflux pump显示文摘 | Jeannot K Elsen S Kohler T | 2008 | Antimicrob Agents Chemother2008，52，7： | 1 |
| 8 | Solvent microextraction into a single drop显示文摘 | Jeannot M A Cantwell F F | 1996 | Anal Chem1996，68，： | 1 |
| 9 | On the distribution of sequential jobs in random brokering for heterogeneous computational grids显示文摘 | Berten V Goossens J Jeannot E | 2006 | IEEE Transactions on Parallel and Distributed Systems2006，17，2： | 1 |
| 10 | Solvent microextraction into a single drop显示文摘 | JEANNOT M A CANTWELL F F | 1996 | Anal Chem1996，68，： | 1 |
| 11 | Advanced AgSnO2 Contact Materials for the Replacement of AgCdO in High Current Contactors显示文摘 | Jeannot D McNeilly K | 2000 | IEEE2000，，： | 1 |
| 12 | Mass tranfer characteristics of solvent extraction into a single drop at the tip of a syringe needle显示文摘 | JEANNOT M A CANTWELL F F | 1997 | Anal Chem1997，69，： | 1 |
| 13 | Molecular Epidemiology ofCarbapenem Non-Susceptible Acinetobacter baumannii in France显示文摘 | Jeannot K Diancourt L Vaux S | 2014 | PLoS One2014，9，11： | 1 |
| 14 | High-speed internal strain measurements in composite structures under dynamic load using embedded FBG sensors 显示文摘 | Jeannot Frieden Joel Cugnoni John Botsis | 2010 | Composite Structures2010，92，： | 1 |
| 15 | On the distribution of sequential jobs in random brokering for heterogeneous computational grids显示文摘 | Berten V Goossens J Jeannot E | 2006 | IEEE Transactions on Parallel and Distributed Systems2006，17，2： | 1 |
| 16 | Genotype-phenotype correlation in hepatocellular adenoma: new classification and relationship with HCC显示文摘 | Zucman-Rossi J Jeannot E Nhieu JT | 2006 | Hepatology2006，43，3： | 1 |
| 17 | Solvent microextraction into a single drop显示文摘 | Jeannot M A Cantwell F F | 1996 | Anal Chem1996，68，13： | 1 |
| 18 | Mass transfer characteristics of solvent extraction into a single drop at the tip of a syringe needle显示文摘 | Jeannot M A Cantwell F F | 1997 | Anal Chem1997，69，2： | 1 |
| 19 | On the Distribution of Sequential Jobs in Random Brokering for Heterogeneous Computational Grids显示文摘 | Berten V Goossens J Jeannot E | 2006 | IEEE Transactions on Parallel and Distributed Systems2006，17，2： | 1 |
| 20 | Solvent microextraction as a speciation tool:determination of free progesterone in a protein solution显示文摘 | Jeannot M A Cantwell F F | 1997 | Anal Chem1997，69，15： | 1 |
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