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| 1 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 2 | 显示文摘 | Cooke D W Bennett B L Farnum E H | 1997 | Appl Phys Lett1997，70，： | 2 |
| 3 | Endoscopic Retrograde Cholangiopancreatography Gut Perforations: When to Wait! When to Operate!显示文摘 | Morgan Katherine A Fontenot Bennett B Ruddy Jean M Mickey Suzanne Adams David B | 2009 | The American Surgeon2009，，6： | 2 |
| 4 | How management style moderates the relationship between abusive supervision and workplace deviance: An uncertainty management theory perspective 显示文摘 | Thau S Bennett R J Mitchell M S Marts M B | 2009 | Organizational Behavior and Human Decision Processes2009，108，： | 1 |
| 5 | Apramycin-resistant Escheriehia coli isolated from pigs and a stockman显示文摘 | Hunter J E B Bennett M Hart C A | 1994 | Epidemiol infect1994，112，： | 1 |
| 6 | Thermostable xylanase10B from Clostridium acetobutylicum ATCC824 显示文摘 | Ali M K Rudolph F B Bennett G N | 2004 | J Industrial Microbiol Biotechnol2004，，： | 1 |
| 7 | Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes显示文摘 | De Waal Malefyt R Abrams J Bennett B | 1991 | The Journal of Experimental Medicine1991，174，5： | 1 |
| 8 | Mechanism of a reaction in vitro associated with delayed-type hypersensitivity显示文摘 | Bloom BR Bennett B | 1966 | Science1966，153，731： | 1 |
| 9 | Nonenzymatic extrac- tion of DNA from blood collected into serum separator tubes 显示文摘 | Siafakas N Burnett L Bennetts B | 1995 | Clin Chem1995，41，7： | 1 |
| 10 | Mechanism of a reaction in vitro associated with delayedtype hypersensitivity显示文摘 | Bloom BR Bennett B | 1966 | Science1966，153，： | 1 |
| 11 | Invasive Pneumococcal Disease in Children 5 Years After Conjugate Vaccine Introduction - Eight States, 1998-2005显示文摘 | Reingold A Hadler J Farley M M Harrison L Lynfield R Lexau C Bennett N Thomas A Craig A S Smith P J Beall B Whitney C G Moore M Pilishvili T | 2008 | MMWR Morbidity and Mortality Weekly Report2008，，6： | 1 |
| 12 | Robust electrical spin injection into a semiconductor heterostructure显示文摘 | Jonker B Park Y Bennett B | | 0，，12： | 1 |
| 13 | The central metabolic pathway from acetyl-CoA to butyryl-CoA in Clostridium acetobutylicum显示文摘 | BENNETT G N RUDOLPH F B | | 0，，03： | 1 |
| 14 | Fault-tolerant design considerations and control strategies for aerospace drives 显示文摘 | BENNETT J W ATKINSON G J MECROW B C | 2012 | IEEE Transactions on Industrial E- lectronics2012，59，5： | 1 |
| 15 | Effect of grain boundary structure on sensitization and corrosion of stainless steel显示文摘 | Bennett B W Pickering H W | 1987 | Metallurgical Transactions A1987，18，： | 1 |
| 16 | Machanism of a reaction in vitro associated with delayed-type hypersensitivity 显示文摘 | Bloom BR Bennett B | 1966 | Science1966，153，： | 1 |
| 17 | The effect of biodegradation and water washing on the occurrence of alkylphenols in crude oils显示文摘 | Taylor P Bennett B Jones M et a1 | 2001 | Organic Geochemistry2001，32，： | 1 |
| 18 | Factors affecting spatial variability in seine net catches of fish in the surf zone of False Bay, South Africa显示文摘 | Clark B M Bennett B A Lamberth S J | 1996 | Mar Ecol Progr Ser1996，131，： | 1 |
| 19 | Mechanism of reaction in vitro associated with delayed type hypersensitivity 显示文摘 | Bloom BR Bennett B | 1996 | Science1996，153，731： | 1 |
| 20 | Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease显示文摘 | WANG Z KLIPFELL E BENNETT B J | 2011 | Nature2011，472，7341： | 1 |
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