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| 1 | Age-related rhesus macaque models of COVID-19显示文摘Background:Since December 2019,an outbreak of the Corona Virus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus(SARS-CoV-2)in Wuhan,China,has become a public health emergency of international concern.The high fatality of aged cases caused by SARS-CoV-2 was a need to explore the possible age-related phenomena with non-human primate models.Methods:Three 3-5 years old and two 15 years old rhesus macaques were intratracheally infected with SARS-CoV-2,and then analyzed by clinical signs,viral replication,chest X-ray,histopathological changes and immune response.Results:Viral replication of nasopharyngeal swabs,anal swabs and lung in old monkeys was more active than that in young monkeys for 14 days after SARS-CoV-2 challenge.Monkeys developed typical interstitial pneumonia characterized by thickened alveolar septum accompanied with inflammation and edema,notably,old monkeys exhibited diffuse severe interstitial pneumonia.Viral antigens were detected mainly in alveolar epithelial cells and macrophages.Conclusion:SARS-CoV-2 caused more severe interstitial pneumonia in old monkeys than that in young monkeys.Rhesus macaque models infected with SARS-CoV-2 provided insight into the pathogenic mechanism and facilitated the development of vaccines and therapeutics against SARS-CoV-2 infection. | Pin Yu Feifei Qi Yanfeng Xu Fengdi Li Peipei Liu Jiayi Liu Linlin Bao Wei Deng Hong Gao Zhiguang Xiang Chong Xiao Qi Lv Shuran Gong Jiangning Liu Zhiqi Song Yajin Qu Jing Xue Qiang Wei Mingya Liu Guanpeng Wang Shunyi Wang Haisheng Yu Xing Liu Baoying Huang Wenling Wang Li Zhao Huijuan Wang Fei Ye Weimin Zhou Wei Zhen Jun Han Guizhen Wu Qi Jin Jianwei Wang Wenjie Tan Chuan Qin | 2020 | Animal Models and Experimental Medicine2020，3，1： | 22 |
| 2 | PRMT5 regulates Golgi apparatus structure through methylation of the golgin GM130显示文摘Golgi 仪器(GA ) 的维护结构和功能取决于 Golgi 矩阵蛋白质。象 golgin 和掌握家庭的成员的 phosphorylation 那样的 Golgi 蛋白质的 posttranslational 修正为决定 Golgi 建筑学是重要的。包括 golgin-84 的一些 Golgi 蛋白质也被知道是 methylated,但是 golgin methylation 的功能仍然保持不清楚。这里,我们证明蛋白质精氨酸 methyltransferase (PRMT5 ) 5 本地化到 GA 和形式建筑群,几个部件在拴住的 GA 带子形成和泡包含了。PRMT5 在 Golgi 带子形成与 PRMT5 原因缺点的 golgin GM130,和弄空交往。而且,在 GM130 的 PRMT5 甲醇化物 N 终端精氨酸,和如此的精氨酸 methylation 为 GA 显得批评带子形成。我们的调查结果揭示 GM130 的 PRMT5 依赖的精氨酸 methylation 由控制 GA 建筑学的维护的分子的机制。 | Zhongwei Zhou Xiaotian Sun Zhenhua Zou Litao Sun Tao Zhang Shaoshi Guo Ya Wen Lin Liu Yi Wang Jun Qin Lei Li Weimin Gong Shilai Bao | 2010 | Cell Research2010，20，9： | 16 |
| 3 | Parameter estimation method based on parameter function surface显示文摘By analyzing the structure of the objective function based on error sum of squares and the information provided by the objective function, the essential problems in the current parameter estimation methods are summarized: (1) the information extracted from the objective function based on error sum of squares is unreasonable or even wrong for parameter estimation; and (2) the surface of the objective function based on error sum of squares is more complex than that of the parameter function, which indicates that the optimal parameter values should be searched on the surface of the parameter function instead of the objective function. This paper proposes the concept of sample intersection and demonstrates the uniqueness theorem of intersection point (namely the uniqueness of optimal parameter values). According to the characteristics of parameter function surface and Taylor series expansion, a parameter estimation method based on the sample intersection information extracted from parameter function surface (PFS method) was constructed. The results of theoretical analysis and practical application show that the proposed PFS method can avoid the problems in the current automatic parameter calibration, and has fast convergence rate and good performance in parameter calibration. | BAO WeiMin ZHANG XiaoQin ZHAO LiPing | 2013 | Science China(Technological Sciences)2013，56，6： | 13 |
| 4 | A semi-physical sediment yield model for estimation of suspended sediment in loess region显示文摘Sediment yield is a complex function of many environmental factors including climate,hydrology,vegetation,basin topography,soil types,and land cover.We present a new semi-physical watershed sediment yield model for the estimation of suspended sediment in loess region.This model is composed by three modules in slope,gully,and stream phases.For slope sediment yield,a balance equation is established based on the concept of hydraulic erosion capacity and soil erosion resistance capacity.According to the statistical analysis of watershed characteristics,we use an exponential curve to approximately describe the spatial variability of watershed soil erosion resistance capacity.In gully phase,the relationship between gully sediment concentration and flow velocity is established based on the Bagnold' stream power function.In the stream phase,we assume a linear dependence of the sediment volume in the reach on the weighted sediment input and output.The proposed sediment yield model is operated in conjunction with a conceptual hydrologic model,and is tested over 16 regions including testing grounds,and small,medium and large watersheds in the loess plateau region in the mid-reach of Yellow River.Our results indicate that the model is reasonable in structure and is able to provide a good simulation of sediment generation and transportation processes at both flood event scale and inter-annual time scale.The proposed model is generally applicable to the watersheds with soil texture similar to that of the loess plateau region in the Yellow River basin in China. | Wei Si Weimin Bao Peng Jiang Liping Zhao Simin Qu | 2017 | International Journal of Sediment Research2017，32，1： | 7 |
| 5 | Indirect Radau pseudospectral method for the receding horizon control problem显示文摘To solve the receding horizon control(RHC) problem in an online manner, a novel numerical method called the indirect Radau pseudospectral method(IRPM) is proposed in this paper. Based on calculus of variations and the first-order necessary optimality condition, the RHC problem for linear time-varying(LTV) system is transformed into the two-point boundary value problem(TPBVP). The Radau pseudospectral approximation is employed to discretize the TPBVP into well-posed linear algebraic equations. The resulting linear algebraic equations are solved via a matrix partitioning approach afterwards to obtain the optimal feedback control law.For the nonlinear system, the linearization method or the quasi linearization method is employed to approximate the RHC problem with successive linear approximations. Subsequently, each linear problem is solved via the similar method which is used to solve the RHC problem for LTV system.Simulation results of three examples show that the IRPM is of high accuracy and of high computation efficiency to solve the RHC problem and the stability of closed-loop systems is guaranteed. | Liao Yuxin Li Huifeng Bao Weimin | 2016 | Chinese Journal of Aeronautics2016，29，1： | 6 |
| 6 | Trajectory generation of heat load test based on gauss pseudospectral method显示文摘A new trajectory generation for heat load test is proposed based on gauss pseudospectral method within limit range. Firstly,with multiple path constraints and flight task requirements taken into consideration, heat load parameters are introduced into the dynamics equations. In order to solve the problem of generating such a trajectory within limit range rapidly, the dynamics equations have been normalized by Earth related parameters. Secondly, since the gauss pseudospectral method is just employed to solve the discrete nonlinear programming problem, transformations are developed, which can relate the Lagrange multipliers of the discrete nonlinear programming problem to the costates of the continuous optimal control problem. In addtion, another approach of trajectory generation by tracking the given heat rate is also presented. Finally, simulation results with common aero vehicle(CAV-H) show that the trajectories obtained by both methods can well perform the heat load test with high stagnation heating rate and the large total aeroheating amount; meanwhile, gauss pseudospectral method is better than the compared one in the given range. Furthermore, the 3-D trajectory states and control variables, angle of attack and bank, which are generated by gauss pseudospectral method, can change smoothly. | ZHANG YuanLong LIU LuHua TANG GuoJian BAO WeiMin | 2018 | Science China(Technological Sciences)2018，61，2： | 6 |
| 7 | Clinicopathological analysis of metaplastic meningioma: report of 15 cases in Huashan Hospital显示文摘Objective: Metaplastic meningioma is a rare subtype of benign meningiomas, classified as WHO grade I with well prognosis. Here we presented our experiences on 15 cases of metaplastic meningioma, to investigate the clinicopathological features, therapies and prognosis of these cases. Methods: 15 patients underwent surgical treatment for intracranial metaplastic meningioma between 2001 and 2010 at Neurosurgery Department of Huashan Hospital, Shanghai, China. The clinical data, radiological manifestation, treatment strategy, pathological findings and prognosis of all patients were analyzed retrospectively. Results: Among the 15 cases (10 males and 5 females), the age ranged from 22 to 74 years old (the mean age was 50.67-year old). The clinical manifestations include headache, dizziness, seizure attack, vision decrease, and weakness of bilateral lower limbs. All the patients received surgical treatment, combined with radiotherapy in some cases. In the follow-up period, recurrence occurred in 2 cases, of which 1 patient died of other system complications. Conclusions: Metaplastic meningiomas are characterized by focal or widespread mesenchymal differentiation with formation of bone, cartilage, fat, and xanthomatous tissue elements. Surgical removal is the optimal therapy, and the overall prognosis is well. But recurrence may occur in some cases, thus radiotherapy is necessary for such kind of patients. | Hailiang Tang Huaping Sun Hong Chen Ye Gong Ying Mao Qing Xie Liqian Xie Mingzhe Zheng Daijun Wang Hongda Zhu Xiaoming Che Ping Zhong Kang Zheng Shiqi Li Weimin Bao Jianhong Zhu Xuanchun Wang Xiaoyuan Feng Xiancheng Chen Liangfu Zhou | 2013 | Chinese Journal of Cancer Research2013，25，1： | 6 |
| 8 | Uncertainty analysis and probabilistic design optimization of hybrid rocket motors for manned lunar landing显示文摘To obtain a conceptual design for a hybrid rocket motor(HRM)to be used as the Ascent Propulsion System in the Apollo lunar module,the deterministic design optimization(DDO)method is applied to the HRM design.Based on the results of an uncertainty analysis of HRMs,an uncertainty-based design optimization(UDO)method is also adopted to improve the design reliability.The HRM design process,which is a multidisciplinary system,is analyzed,and a mathematical model for the system design is established to compute the motor performance from the input parameters,including the input variables and model parameters.The input parameter uncertainties are quantified,and a sensitivity analysis of the model parameter uncertainties is conducted to identify the most important model parameter uncertainties for HRMs.The DDO and probabilistic UDO methods are applied to conceptual designs for an HRM to be used as a substitute for the liquid rocket motor(LRM)of the Ascent Propulsion System.The conceptual design results show that HRMs have several advantages as an alternative to the LRM of the Ascent Propulsion System,including nontoxic propellant combination,small motor volume,and comparable functions,such as restarting and throating.Comparisons of the DDO and UDO results indicate that the UDO method achieves more robust and reliable optimal designs than the DDO method.The probabilistic UDO method can be used to develop better conceptual designs for HRMs. | ZHU Hao TIAN Hui CAI GuoBiao BAO WeiMin | 2015 | Science China(Technological Sciences)2015，58，7： | 4 |
| 9 | Uncertainty analysis and design optimization of hybrid rocket motor powered vehicle for suborbital flight显示文摘In this paper, we propose an uncertainty analysis and design optimization method and its applications on a hybrid rocket motor(HRM) powered vehicle. The multidisciplinary design model of the rocket system is established and the design uncertainties are quantified. The sensitivity analysis of the uncertainties shows that the uncertainty generated from the error of fuel regression rate model has the most significant effect on the system performances. Then the differences between deterministic design optimization(DDO) and uncertainty-based design optimization(UDO) are discussed. Two newly formed uncertainty analysis methods, including the Kriging-based Monte Carlo simulation(KMCS) and Kriging-based Taylor series approximation(KTSA), are carried out using a global approximation Kriging modeling method. Based on the system design model and the results of design uncertainty analysis, the design optimization of an HRM powered vehicle for suborbital flight is implemented using three design optimization methods: DDO, KMCS and KTSA. The comparisons indicate that the two UDO methods can enhance the design reliability and robustness. The researches and methods proposed in this paper can provide a better way for the general design of HRM powered vehicles.In this paper,we propose an uncertainty analysis and design optimization method and its applications on a hybrid rocket motor(HRM)powered vehicle.The multidisciplinary design model of the rocket system is established and the design uncertainties are quantified.The sensitivity analysis of the uncertainties shows that the uncertainty generated from the error of fuel regression rate model has the most significant effect on the system performances.Then the differences between deterministic design optimization(DDO)and uncertainty-based design optimization(UDO)are discussed.Two newly formed uncertainty analysis methods,including the Kriging-based Monte Carlo simulation(KMCS)and Kriging-based Taylor series approximation(KTSA),are carried out using a global approximation Kriging modeling method.Based on the system design model and the results of design uncertainty analysis,the design optimization of an HRM powered vehicle for suborbital flight is implemented using three design optimization methods:DDO,KMCS and KTSA.The comparisons indicate that the two UDO methods can enhance the design reliability and robustness.The researches and methods proposed in this paper can provide a better way for the general design of HRM powered vehicles. | Zhu Hao Tian Hui Cai Guobiao Bao Weimin | 2015 | Chinese Journal of Aeronautics2015，28，3： | 4 |
| 10 | Three-dimensional nonlinear coupling guidance for hypersonic vehicle in dive phase显示文摘Three-dimensional(3D)nonlinear diving guidance strategy considering the coupling between longitudinal and lateral motions for hypersonic vehicle is investigated in this paper.It constructs the complete nonlinear coupling motion equation without any approximations based on diving relative motion relationship directly,and converts it into linear state space equation with the same relative degree by feedback linearization.With the linear equation,slide mode control with strong robustness is employed to design the guidance law,and 3D diving guidance law which can satisfy terminal impact point and falling angle constraints with high precision is obtained by substituting the previous control law into the origin nonlinear guidance system.Besides,regarding lateral overload as the standard,hybrid control strategy which can take full advantage of the excellent characters of both bank-to-turn(BTT)and skid-to-turn(STT)controls is designed to improve the guidance accuracy further.Finally,the results of CAV-H vehicle guidance test show that the algorithm can realize high accuracy guidance even if serious motion coupling exists,and has strong robustness to the path disturbances and navigation errors as well. | ZHU JianWen LIU LuHua TANG GuoJian BAO WeiMin | 2014 | Science China(Technological Sciences)2014，57，9： | 3 |
| 11 | Extended differential geometric guidance law for intercepting maneuvering targets显示文摘Without assumptions made on motion states of missile and target, an extended differential geometric guidance law is derived. Through introducing a line of sight rotation coordinate system, the derivation is simplified and has more explicit physical significances. The extended law is theoretically applicable to any engagement scenarios. Then, on basis of the extended law, a modified one is designed without the requirement of target acceleration and an approach is proposed to determining the applied direction of commanded missile acceleration. Qualitative analysis is carried out to study the capture performance and a criterion for capture is given. Simulation results indicate the two laws are effective and make up the deficiency that pure proportional navigation suitable for endoatmospheric interceptions cannot deal with high-speed maneuvering targets. Furthermore, the correctness of the criterion is validated. | HUANG Jingshuai ZHANG Hongbo TANG Guojian BAO Weimin | 2018 | Journal of Systems Engineering and Electronics2018，29，5： | 3 |
| 12 | Evolutionary transition between invertebrates and vertebrates via methylation reprogramming in embryogenesis显示文摘Major evolutionary transitions are enigmas,and the most notable enigma is between invertebrates and vertebrates,with numerous spectacular innovations.To search for the molecular connections involved,we asked whether global epigenetic changes may offer a clue by surveying the inheritance and reprogramming of parental DNA methylation across metazoans.We focused on gametes and early embryos,where the methylomes are known to evolve divergently between fish and mammals.Here,we find that methylome reprogramming during embryogenesis occurs neither in pre-bilaterians such as cnidarians nor in protostomes such as insects,but clearly presents in deuterostomes such as echinoderms and invertebrate chordates,and then becomes more evident in vertebrates.Functional association analysis suggests that DNA methylation reprogramming is associated with development,reproduction and adaptive immunity for vertebrates,but not for invertebrates.Interestingly,the single HOX cluster of invertebrates maintains unmethylated status in all stages examined.In contrast,the multiple HOX clusters show dramatic dynamics of DNA methylation during vertebrate embryogenesis.Notably,the methylation dynamics of HOX clusters are associated with their spatiotemporal expression in mammals.Our study reveals that DNA methylation reprogramming has evolved dramatically during animal evolution,especially after the evolutionary transitions from invertebrates to vertebrates,and then to mammals. | Xiaocui Xu Guoqiang Li Congru Li Jing Zhang Qiang Wang David KSimmons Xuepeng Chen Naveen Wijesena Wei Zhu Zhanyang Wang Zhenhua Wang Bao Ju Weimin Ci Xuemei Lu Daqi Yu Qian-fei Wang Neelakanteswar Aluru Paola Oliveri Yong EZhang Mark QMartindale Jiang Liu | 2019 | National Science Review2019，6，5： | 2 |
| 13 | Preparation of Au nanoparticles modified TiO_2 nanotube array sensor and its application as chemical oxygen demand sensor显示文摘Au nanoparticles(AuNPs) were electrodeposited at the highly ordered anatase TiO_2 nanotube array(TiO_2 NA) electrode under sonicating, and the AuNP-TiO_2 NA sensor was characterized by scanning electron microscope(SEM), X-ray photoelectron spectroscopy(XPS), X-ray diffraction(XRD). The photoelectrochemical experiments indicate the AuNP-TiO_2 NA sensor has lower photoelectro-resistance,higher photoelectrocatalytical activity and stability than that of pure TiO_2 NA sensor under the same conditions. The as-prepared sensor can be used for the determination of chemical oxygen demand(COD)in real samples, and the obtained results are comparable well with those of by standard K_2Cr_2O_7 method.The method proposed is simple, fast, cost effective, and environmentally friendly. | Longqi Liang Jiao Yin Jinpeng Bao Linchuan Cong Weimin Huang Haibo Lin Zhan Shi | 2019 | Chinese Chemical Letters2019，30，1： | 2 |
| 14 | Effect of calcium on the microstructure and mechanical properties of brazed joint using Ag–Cu–Zn brazing filler metal显示文摘 | Fangfei Sui Weimin Long Shengxin Liu Guanxing Zhang Li Bao Hao Li Yong Chen | 2013 | Materials and Design2013，，： | 2 |
| 15 | Establishing a protein expression profile database for the normal human pituitary gland using two-dimensional high-performance liquid chromatography combined with LTQ-Orbitrap mass spectrometry显示文摘In this study, we selected adult normal pituitary gland tissues from six patients during operations for pituitary microadenomas via the transsphenoidal approach for extended normal pituitary tissue resection around the tumor, and analyzed the protein expression of human normal pituitary using two-dimensional high-performance liquid chromatography combined with LTQ-Orbitrap mass spectrometry proteomics technology. The ten most highly expressed proteins in normal human pituitary were: alpha 3 type VI collagen isoform 5 precursor (abundance among tall pituitary proteins, 1.30%), fibrinogen beta chain preproprotein (0.99%), vimentin (0.73%), prolactin (0.69%), ATP synthase, H + transporting and mitochondrial F1 complex beta subunit precursor (0.52%), keratin Ⅰ (0.49%), growth hormone (0.45%), carbonic anhydrase Ⅰ (0.40%), heat shock protein 90 kDaⅠ (0.31%), and annexin V (0.30%). Based on the biological function classifications of these proteins, the top three categories by content were neuroendocrine proteins (abundance among all pituitary proteins, 40.1%), catalytic and metabolic proteins (28.3%), and cell signal transduction proteins (9.8%). Based on cell positioning classification, the top three categories were cell organelle (24.5%), membrane (20.8%), and cytoplasm (13.0%). Based on biological process classification, the top three categories of proteins are involved in physiological processes (42.9%), cellular processes (40.4%), and regulation of biological processes (9.1%). Our experimental findings indicate that a protein expression profile database of normal human pituitary can be precisely and efficiently established by proteomics technology. | Rong Xie Wei Xu Weimin Bao Hang Liu Luping Chen Yiwen Shen Jianhong Zhu | 2012 | Neural Regeneration Research2012，7，36： | 2 |
| 16 | Shear strength of an unsaturated weakly expansive soil显示文摘To study the weakly expansive clay obtained from a slope along Wuhan-Shiyan expressway in Hubei Province,soil-water property tests and some unsaturated triaxial tests with suction control were conducted,and the soil-water retention curve(SWRC) and unsaturated shear strength of this soil were obtained.Results show that the air-entry suction and the residual degree of saturation of the tested soil are 106 kPa and 8%,respectively.The boundary effect zone and the transition zone can be identified on the desorption curve,but the residual zone is not so obvious.The unsaturated shear strength increases as suction increases within the range of controlled suction in the test,and friction angle,~b,in the triaxial shear test is 17.6°.Based on the results,constitutive models for predicting the unsaturated shear strength using the SWRC were evaluated,and comparisons between prediction and measurement were made.It is concluded that for engineering purpose,the constitutive model should be carefully selected based on soil properties when predicting the unsaturated shear strength using the SWRC. | Weimin Ye Yawei Zhang Bao Chen Xiuhan Zhou Qiang Xie | 2010 | Journal of Rock Mechanics and Geotechnical Engineering2010，2，2： | 2 |
| 17 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 18 | Structural Deformation Monitoring of Flight Vehicles Based on Optical Fiber Sensing Technology:A Review and Future Perspectives显示文摘Structural deformation monitoring of flight vehicles based on optical fiber sensing(OFS)technology has been a focus of research in the field of aerospace.After nearly 30 years of research and development,Chinese and international researchers have made significant advances in the areas of theory and methods,technology and systems,and ground experiments and flight tests.These advances have led to the development of OFS technology from the laboratory research stage to the engineering application stage.However,a few problems encountered in practical applications limit the wider application and further development of this technology,and thus urgently require solutions.This paper reviews the history of research on the deformation monitoring of flight vehicles.It examines various aspects of OFS-based deformation monitoring including the main varieties of OFS technology,technical advantages and disadvantages,suitability in aerospace applications,deformation reconstruction algorithms,and typical applications.This paper points out the key unresolved problems and the main evolution paradigms of engineering applications.It further discusses future development directions from the perspectives of an evolution paradigm,standardization,new materials,intelligentization,and collaboration. | Lianqing Zhu Guangkai Sun Weimin Bao Zheng You Fanyong Meng Mingli Dong | 2022 | Engineering2022，，9： | 1 |
| 19 | Parameter esti- mation method based on parameter function surface显示文摘 | BAO WeiMin ZHANG XiaoQin ZHAO LiPing | | Science0，，： | 1 |
| 20 | Estimating selected parameters for the XAJ model under muhicollinearity among watershed characteristies 显示文摘 | BAO Weimin LI Qian | 2012 | Journal of Hydrologic Engineering2012，17，1： | 1 |
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