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| 1 | Pulmonary involvement in inflammatory bowel disease显示文摘AIM:To determine the relationship of pulmonary abnormalities and bowel disease activity in inflammatory bowel disease(IBD).METHODS:Thirty ulcerative colitis(UC)and nine Crohn's disease patients,and 20 control subjects were enrolled in this prospective study.Detailed clinical information was obtained.Extent and activity of the bowel disease were established endoscopically.Each patient underwent pulmonary function tests and high-resolution computed tomography(HRCT).Blood samples for measurement of C-reactive protein(CRP),erythrocyte sedimentation rate(ESR),angiotensin converting enzyme and total IgE were delivered by the patients.RESULTS:Ten(25.6%)patients had respiratory symptoms.A pulmonary function abnormality was present in 22 of 39 patients.Among all patients,the most prevalent abnormalities in lung functions were a decrease in forced expiratory volume in 1 s(FEV1),FEV1/forced vital capacity(FVC),forced expiratory flow(FEF)25%-75%,transfer coefficient for carbon monoxide(DLCO),DLCO/alveolar volume.Increased respiratory symptoms score was associated with high endoscopic activity index in UC patients.Endoscopic and clinical activities in UC patients were correlated with FEV1,FEV1/FVC,and FEF 25%-75%.Smoking status,duration of disease and medication were not correlated with pulmonary physiological test results,HRCT abnormalities,clinical/endoscopic disease activity,CRP,ESR or total IgE level or body mass index.CONCLUSION:It is important that respiratory manifestations are recognized and treated early in IBD.Otherwise,they can lead to destructive and irreversible changes in the airway wall. | Aydin Yilmaz Nilgün Yilmaz Demirci Derya Hosgün Enver ner Yurdanur Erdogan Atila Gkek Atalay aglar | 2010 | World Journal of Gastroenterology2010，16，39： | 15 |
| 2 | Pegylated interferon-alpha plus taurine in treatment of rat liver fibrosis显示文摘AIM: To investigate the antif ibrotic effects of peginterferon- alpha 2b and taurine on oxidative stress markers and hepatocellular apoptosis. METHODS: Sixty rats with CCl4-induced liver fibrosis were divided into 4 groups (n = 15). Group 1 was left for spontaneous recovery (SR). Groups 2-4 received peginterferon-alpha 2b, taurine, and their combination, respectively, for four weeks. Histological f ibrosis scores, histomorphometric analysis, tissue hydroxyproline, tissue MDA, GPx and SOD activities were determined. Activated stellate cells and hepatocellular apoptosis were also evaluated. RESULTS: The degree of f ibrosis decreased in all treatment groups compared to spontaneous recovery group. Taurine alone and in combination with peginterferon-alpha 2b reduced oxidative stress markers, but peginterferon-alpha 2b alone did not. Apoptotic hepatocytes and activated stellate cells were higher in groups 2-4 than in group 1. Combined taurine and peginterferon-alpha 2b further reduced fibrosis and increased activated stellate cell apoptosis, but could not improve oxidative stress more than taurine alone.CONCLUSION: Peginterferon-alpha 2b exerts anti- f ibrotic effects on rat liver fibrosis. It seems ineffective against oxidative stress in vivo. Peginterferon-alpha 2b in combination with taurine seems to be an antif ibrotic strategy. | Ilker Tasci Mehmet Refik Mas Sevil Atalay Vural Salih Deveci Bilgin Comert Gunay Alcigir Nuket Mas Cemal Akay Mithat Bozdayi Cihan Yurdaydin Hakan Bozkaya Ozden Uzunalimoglu Ahmet Turan Isik Harun M Said | 2007 | World Journal of Gastroenterology2007，13，23： | 7 |
| 3 | Confounders of uric acid level for assessing cardiovascular outcomes显示文摘We read the article entitled Serum uric acid as a prognostic marker in the setting of advanced vascular disease:a prospective study in the elderly by Stolfo,et al.[1] with great interest.The authors evaluated the association of serum uric acid (SUA) levels with adverse cardiovascular events and deaths in an elderly population affected by advanced atherosclerosis.They founded meaningful association between SUA levels and of cardiovascular events and cancer related death.We believe that these findings will lead for further studies on uric acid. | Mehmet Dogan Omer Uz Mustafa Aparci Murat Atalay | 2016 | Journal of Geriatric Cardiology2016，13，2： | 6 |
| 4 | Predisposing factors and surgical outcome of complicated liver hydatid cysts显示文摘AIM: To evaluate the predisposing factors for peritoneal perforation and intrabiliary rupture and the effects of these complications on surgical outcome in liver hydatid disease.METHODS: A total of 372 patients with liver hydatid cysts who had undergone surgical treatment were evaluated retrospectively. Twenty eight patients with peritoneal perforation, 93 patients with spontaneous intrabiliary perforation, and 251 patients with noncomplicated hydatid cysts were treated in our clinics.RESULTS: When the predisposing factors for complications were evaluated, younger age, superf icial position, and larger cyst dimensions (P < 0.05; range, 0.0010.017) increased peritoneal perforation rates. It was shown that older age increased cyst dimensions, and presence of multiple and bilobar cysts increased intrabiliary rupture rates (P < 0.05; range, 0.0010.028). Partial pericystectomy and drainage was the most frequent surgical procedure in all groups (71.6%). The incidence of postoperative complications in the peritoneal perforated group, in the intrabiliary ruptured group, and in the noncomplicated group was 25%, 16.1% and 5.5%, respectively. When compared, complication rates were significantly different (P = 0.002). When length of hospital stay was compared, there was no signif icant difference between the groups (P > 0.05). The overall recurrence rate was 3.8% (14 patients), but there was not any statistical difference among the patient groups (P = 0.13). The early postoperative mortality rate was 1.1%. CONCLUSION: In peritoneally perforated and intrabiliary ruptured cases, the most important steps are irrigation of the peritoneal cavity and clearance of the cystic material from the biliary tree. | Alper Akcan Erdogan Sozuer Hizir Akyildiz Zeki Yilmaz Ahmet Ozturk Altay Atalay | 2010 | World Journal of Gastroenterology2010，16，24： | 4 |
| 5 | Clinical evaluation of implants in patients with maxillofacial defects显示文摘AIM: To show the efficacy of reconstruction and rehabilitation of large acquired maxillofacial defects due to tumor resections and firearm injuries. METHODS: The study group comprised of 16 patients(10 men and 6 women) who were operated on because of their maxillofacial defects under local and general anesthesia between June 2007 and June 2011. Prosthetic treatment with the aid of dental implants was performed for all of the patients. Eight patients received an implant supported fixed prosthesis; six patients received implant supported overdentures and two patients received both. Patients were followed up postoperatively for 1 to 4 years. Implant success and survival rates were recorded. Panoramic radiographs were taken preoperatively, immediately after surgery, immediately after loading and at every recall session. Peri-implant and prosthetic complications were recorded. Subjects were asked to grade their oral health satisfaction after treatment according to 100 mm visual analog scale(VAS) and the oral health related quality oflife of the patients was measured with the short-form Oral Health Impact Profile. RESULTS: Five implants(3 in the mandible, 2 in the maxilla) in five patients were lost, while the other 53 survived, which brings an overall survival rate of 91.37% on the implant basis, but 68.75% on patient basis. All the failed implants were lost before abutment connection and were therefore regarded as early failures. For all failed implants, new implants were placed after a 2 mo period and the planning was maintained. The mean marginal bone loss(MBL) was 1.4 mm on the mesial side and 1.6 mm on the distal side of the implants. Five of the implants showed MBL > 2 mm(mean MBL = 2.3 mm) but less than 1/2 of the implant bodies and therefore were regarded as not successful but surviving implants. The VAS General Comfort mean score was 85.07, the VAS Speech mean score was 75.25 and the VAS Esthetics mean score was 82.74. No patient reported low scores(score lower than 50) of satisfaction in any of the evaluated factors. The mean of OHIP-14 scores was 5.5. CONCLUSION: Although further follow up and larger case numbers will give more information about the success of dental implants as a treatment modality in maxillofacial defects patients, the actual results are encouraging and can be recommended for similar cases. | Belir Atalay Hakan Bilhan Onur Geckili Caglar Bilmenoglu Ugur Meric | 2013 | World Journal of Stomatology2013，2，3： | 3 |
| 6 | New concepts in axillary management of breast cancer显示文摘In the last decades, surgical treatment of breast cancer has evolved from more extensive procedures like radical mastectomy to less invasive breast conserving surgery. Similarly, surgical management of axilla has enormously changed from routine axillary dissection to sentinel lymph node biopsy. Traditional surgical approach to the axilla in case of sentinel lymph node negativity is to avoid completion axillary dissection. However, surgeons even avoid performing axillary dissection in selected patients with positive sentinel lymph node in clinical practice depending on the recent randomized controlled studies supporting this concept. All of the recent changes in the management of positive axilla necessitate surgeons to refresh their knowledge on this challenging topic. | Can Atalay | 2014 | World Journal of Clinical Oncology2014，5，5： | 2 |
| 7 | The effect of transcutaneous electrical nerve stimulation on postmastectomy skin flap necrosis显示文摘 | Can Atalay Kerim Bora Yilmaz | 2009 | Breast Cancer Research and Treatment2009，，3： | 2 |
| 8 | The effect of metoclopramide on gastric emptying in traumatic brain injury显示文摘 | Tarik Zafer Nursal Bulent Erdogan Turgut Noyan Melih Cekinmez Betul Atalay Nevzat Bilgin | 2005 | Journal of Clinical Neuroscience2005，，4： | 2 |
| 9 | Acute myocardial infarction and sub-acute stent thrombosis associated with occult essential thrombocythemia显示文摘A70-year-old female with no previous cardiac history presented with complaints of severe chest and back pain lasting for 20 minutes.She had a past history of type 2 diabetes mellitus for five years and hypertension for twenty years,but denied a history of hyperlipidemia,smoking or hemorrhagic disorder.There was no family history of coronary artery or hematologic disease.On physical examination,the blood pressure was 145/90 mmHg and the heart rate was 102 beats/min.Cardiac examination revealed normal S1 and S2 sounds.There were no murmors or clicks.The lungs were clear on auscultation.Hepatosplenomegaly or lymphadenopathy was not detected.Her electrocardiogram showed ST elevations in lead V1-V6,consistent with acute anterior MI and echocardiogram supported the diagnosis with a slight reduction in wall motion in the anterior region. | Zafer Isilak Mehmet Tezcan Murat Atalay Ejder Kardesoglu | 2014 | Chinese Medical Journal2014，，19： | 2 |
| 10 | Augmentation of a loosened sacral pedicle screw with percutaneous polymethylmethacrylate injection 显示文摘 | Yilmaz C Atalay B Caner H | 2006 | J Spinal Disord Tech2006，5，： | 1 |
| 11 | Alpha-lipoic acid supplentation:tissue glutathione homeostasis at rest and after exercise显示文摘 | Khanna S Atalay M Laaksonen D E | 1999 | J Appl Physiol1999，86，： | 1 |
| 12 | Mater Sci Eng A显示文摘 | Atalay S Adiguzel H I Kamerb O | 2001 | 304-306:4952001，，： | 1 |
| 13 | Remaufacturing as a marketing strategy显示文摘 | Atalay Atasu M iklos Sarvary Wassenhove L N V | 2008 | Management Science2008，54，10： | 1 |
| 14 | The effect of magnesium sulfate treatment onserum cardiac troponin I levels in preeclamptic women显示文摘 | Atalay CjErden G Turhan T | 2005 | Acta Obstet GynecolScand2005，84，7： | 1 |
| 15 | Modified Limberg transposition flap in the treatment of pilonidal sinus disease显示文摘 | B. Kaya C. Eris S. Atalay O. Bat N. E. Bulut B. Mantoglu K. Karabulut | 2012 | Techniques in Coloproctology2012，，1： | 1 |
| 16 | Phys B显示文摘 | Atalay F E Kaya H Atalay S | 2006 | 371:3272006，371，： | 1 |
| 17 | Identification of the culprit artery involved in inferior wall acute myocardial infarction using electrocardiographic criteria显示文摘 | Atalay C | 2004 | J Int Med Res2004，32，1： | 1 |
| 18 | Non-Hodgkin's Lymphoma of the female urethra pressenting as a caruncle显示文摘 | Atalay AC Karaman MI Basak T | 1998 | Int Urol Nephrol1998，30，5： | 1 |
| 19 | Network structure of production显示文摘 | Atalay E Hortacsu A Roberts J | 2011 | Proceedings of the National Academy of Scien- ces of the United States of America2011，108，13： | 1 |
| 20 | Spontaneous resolution of lumbar vertebral eosinophilic granuloma 显示文摘 | Bavbek M Atalay B Altinors N | 2004 | Acta Neurochir (Wien)2004，146，6： | 1 |
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