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| 1 | Bone graft substitutes for spine fusion: A brief review显示文摘Bone graft substitutes are widely used in the field of orthopedics and are extensively used to promote vertebral fusion. Fusion is the most common technique in spine surgery and is used to treat morbidities and relieve discomfort. Allograft and autograft bone substitutes are currently the most commonly used bone grafts to promote fusion. These approaches pose limitations and present complications to the patient. Numerous alternative bone graft substitutes are on the market or have been developed and proposed for application. These options have attempted to promote spine fusion by enhancing osteogenic properties. In this review, we reviewed biology of spine fusion and the current advances in biomedical materials and biological strategies for application in surgical spine fusion. Our findings illustrate that, while many bone graft substitutes perform well as bone graft extenders, only osteoinductive proteins(recombinant bone morphogenetic proteins-2 and osteogenic protein-1) provide evidence for use as both bone enhancers and bone substitutes for specific types of spinal fusion. Tissue engineered hydrogels, synthetic polymer composites and viral based gene therapy also holds the potential to be used for spine fusion in future, though warrants further investigation to be used in clinical practice. | Ashim Gupta Nitin Kukkar Kevin Sharif Benjamin J Main Christine E Albers Saadiq F El-Amin Ⅲ | 2015 | World Journal of Orthopedics2015，6，6： | 4 |
| 2 | Role of <sup>18</sup> F ‐fluorodeoxyglucose positron emission tomography/computed tomography in the characterization of pancreatic masses: Experience from tropics显示文摘 | Sampath Santhosh Bhagwant Rai Mittal Deepak Bhasin Radhika Srinivasan Surinder Rana Ashim Das Ritambhra Nada Anish Bhattacharya Rajesh Gupta Rakesh Kapoor | 2013 | J Gastroenterol Hepatol2013，，2： | 2 |
| 3 | Application of GIS and crop growth models in estimating water productivity显示文摘 | Amor V.M Ines Ashim Das Gupta Rainer Loof | 2002 | Agricultural Water Management2002，，3： | 1 |
| 4 | Reservoir operation and evaluation of downstream flow augmentation 显示文摘 | Mahesh Kumar Sahu Ashim Das Gupta | 2001 | Journal of the American Water Resources Association (S1093-474X)2001，37，3： | 1 |
| 5 | Primary Malignant Melanoma of the Esophagus: Long-Term Survival After Radical Resection显示文摘 | Vikas Gupta Rakesh Kochhar Saroj Kant Sinha Ashim Das | 2009 | Journal of Thoracic Oncology2009，，9： | 1 |
| 6 | Drought Analysis in the Awash River Basin, Ethiopia显示文摘 | Desalegn Chemeda Edossa Mukand Singh Babel Ashim Das Gupta | 2010 | Water Resources Management2010，，7： | 1 |
| 7 | Assessment of different irrigation management models in Vietnam显示文摘 | Das Gupta Ashim Babel Mukand Singh | 2005 | International Journal of Water Resources Development2005，21，3： | 1 |
| 8 | Combining remote sensing - simulation modelingand genetic algorithm optimization to explore water management options in irrigated agriculture显示文摘 | Amor V M Ines Kiyoshi Honda Ashim Das Gupta | 2006 | Agricultural Water Management2006，83，： | 1 |
| 9 | Role of <sup>18</sup> F ‐fluorodeoxyglucose positron emission tomography/computed tomography in the characterization of pancreatic masses: Experience from tropics显示文摘 | Sampath Santhosh Bhagwant Rai Mittal Deepak Bhasin Radhika Srinivasan Surinder Rana Ashim Das Ritambhra Nada Anish Bhattacharya Rajesh Gupta Rakesh Kapoor | 2013 | J Gastroenterol Hepatol2013，，2： | 1 |
| 10 | Silver nanoparticle technology in orthopaedic infections显示文摘The irrational and prolonged use of antibiotics in orthopaedic infections poses a major threat to the development of antimicrobial resistance.To combat antimi-crobial resistance,researchers have implemented various novel and innovative modalities to curb infections.Nanotechnology involves doping ions/metals onto the scaffolds to reach the target site to eradicate the infective foci.In this conno-tation,we reviewed silver nanoparticle technology in terms of mechanism of action,clinical applications,toxicity,and regulatory guidelines to treat ortho-paedic infections. | Madhan Jeyaraman Naveen Jeyaraman Arulkumar Nallakumarasamy Karthikeyan P Iyengar Vijay Kumar Jain Anish G Potty Ashim Gupta | 2023 | World Journal of Orthopedics2023，14，9： | 0 |
| 11 | Machine learning and deep neural network-based learning in osteoarthritis knee显示文摘Osteoarthritis(OA)of the knee joint is considered the commonest musculoskeletal condition leading to marked disability for patients residing in various regions around the globe.Application of machine learning(ML)in doing research regarding OA has brought about various clinical advances viz,OA being diagnosed at preliminary stages,prediction of chances of development of OA among the population,discovering various phenotypes of OA,calculating the severity in OA structure and also discovering people with slow and fast progression of disease pathology,etc.Various publications are available regarding machine learning methods for the early detection of osteoarthritis.The key features are detected by morphology,molecular architecture,and electrical and mechanical functions.In addition,this particular technique was utilized to assess non-interfering,non-ionizing,and in-vivo techniques using magnetic resonance imaging.ML is being utilized in OA,chiefly with the formulation of large cohorts viz,the OA Initiative,a cohort observational study,the Multicentre Osteoarthritis Study,an observational,prospective longitudinal study and the Cohort Hip&Cohort Knee,an observational cohort prospective study of both hip and knee OA.Though ML has various contributions and enhancing applications,it remains an imminent field with high potential,also with its limitations.Many more studies are to be carried out to find more about the link between machine learning and knee osteoarthritis,which would help in the improvement of making decisions clinically,and expedite the necessary interventions. | Harish V K Ratna Madhan Jeyaraman Naveen Jeyaraman Arulkumar Nallakumarasamy Shilpa Sharma Manish Khanna Ashim Gupta | 2023 | World Journal of Methodology2023，13，5： | 0 |
| 12 | Long noncoding RNAs in mesenchymal stromal/stem cells osteogenic differentiation:Implications in osteoarthritis pathogenesis显示文摘This letter focuses on a recently published article that provided an exceptional description of the effect of epigenetic modifications on gene expression patterns related to skeletal system remodeling.Specifically,it discusses a novel modality of epigenetic regulation,the long noncoding RNAs(lncRNAs),and provides evidence of their involvement in mesenchymal stromal/stem cells osteo-/adipogenic differentiation balance.Despite focus on lncRNAs,there is an emerging cross talk between lncRNAs and miRNAs interaction as a novel mechanism in the regulation of the function of the musculoskeletal system,by controlling bone homeostasis and bone regeneration,as well as the osteogenic differentiation of stem cells.Thus,we touched on some examples to demonstrate this interaction.In addition,we believe there is still much to discover from the effects of lncRNAs on progenitor and non-progenitor cell differentiation.We incorporated data from other published articles to review lncRNAs in normal progenitor cell osteogenic differentiation,determined lncRNAs involved in osteoarthritis pathogenesis in progenitor cells,and provided a review of lncRNAs in non-progenitor cells that are differentially regulated in osteoarthritis.In conclusion,we really enjoyed reading this article and with this information we hope to further our understanding of lncRNAs and mesenchymal stromal/stem cells regulation. | Daniel Quintero Hugo C Rodriguez Anish G Potty Dimitrios Kouroupis Ashim Gupta | 2022 | World Journal of Stem Cells2022，14，6： | 0 |
| 13 | FDGPET/CT显像对初次分期胰腺癌患者的转移评估优于增强CT显示文摘【摘要】目的评价脱氧葡萄糖(FDG)PET/CT在胰腺癌初次分期中较常规多相增强cT(CECT)的增益作用。方法54例病理证实的胰腺癌患者行FDGPET/CECT显像,计算PET/CT和CECT在淋巴结分期和转移分期中的灵敏度、特异性、阳性NN值(PPV)、阴性预测值(NPV)和准确性。 | 唐军 Sampath Santhosh Bhagwant Rai Mittal Deepak Kumar Bhasin Surinder Singh Rana Rajesh Gupta Ashim Das Ritambhra Nada | 2018 | 中华核医学与分子影像杂志2018，38，4： | 0 |
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