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| 1 | Factors influencing health-related quality of life in chronic liver disease显示文摘AIM: To investigate the factors contributing to health- related quality of life (HRQL) in chronic liver disease (CLD). METHODS: Patients with CLD and age- and sex- matched normal subjects performed the validated Thai versions of the short-form 36 (SF-36) by health survey and chronic liver disease questionnaire (CLDQ). Stepwise multiple regression analysis was used to assess the impact of disease severity, demography, causes of CLD, socioeconomic factors, and self-rating health perception on HRQL. RESULTS: Two-hundred and fifty patients with CLD and fifty normal subjects were enrolled into the study. Mean age and the numbers of low educated, unemployed, blue-collar career and poor health perception increased significantly from chronic hepatitis to Child’s Classes A to B to C. Advanced stage of CLD was related to deterioration of HRQL. Increasing age and female reduced physical health area. Low socioeconomic factors and financial burden affected multiple areas of HRQL. In overall, the positive impact of self-rating health perception on HRQL was consistently showed. CONCLUSION: Advanced stages of chronic liver disease, old age, female sex, low socioeconomic status and financial burden are important factors reducing HRQL. Good health perception improves HRQL regardless of stages of liver disease. | Abhasnee Sobhonslidsuk Chatchawan Silpakit Ronnachai Kongsakon Patchareeya Satitpornkul Chaleaw Sripetch Anya Khanthavit | 2006 | World Journal of Gastroenterology2006，12，48： | 7 |
| 2 | Molecular alterations in gastric cancer with special reference to the early-onset subtype显示文摘Currently, gastric cancer(GC) is one of the most frequently diagnosed neoplasms, with a global burden of 723000 deaths in 2012. It is the third leading cause of cancer-related death worldwide. There are numerous possible factors that stimulate the procarcinogenic activity of important genes. These factors include genetic susceptibility expressed in a singlenucleotide polymorphism, various acquired mutations(chromosomal instability, microsatellite instability, somatic gene mutations, epigenetic alterations) and environmental circumstances(e.g., helicobcter pylori infection, EBV infection, diet, and smoking). Most of the aforementioned pathways overlap, and authors agree that a clear-cut pathway for GC may not exist. Thus, the categorization of carcinogenic events is complicated. Lately, it has been claimed that research on early-onset gastric carcinoma(EOGC) and hereditary GC may contribute towards unravelling some part of the mystery of the GC molecular pattern because young patients are less exposed to environmental carcinogens and because carcinogenesis in this setting may be more dependent on genetic factors. The comparison of various aspects that differ and coexist in EOGCs and conventional GCs might enable scientists to: distinguish which features in the pathway of gastric carcinogenesisare modifiable, discover specific GC markers and identify a specific target. This review provides a summary of the data published thus far concerning the molecular characteristics of GC and highlights the outstanding features of EOGC. | Malgorzata Skierucha Anya NA Milne G Johan A Offerhaus Wojciech P Polkowski Ryszard Maciejewski Robert Sitarz | 2016 | World Journal of Gastroenterology2016，22，8： | 6 |
| 3 | Nature meets nurture: molecular genetics of gastric cancer显示文摘 | Anya N. Milne F. Carneiro C. O’Morain G. J. A. Offerhaus | 2009 | Human Genetics2009，，5： | 4 |
| 4 | Evaluation of an erosion-sediment transport model for a hillslope using laboratory flume data显示文摘Climate change can escalate rainfall intensity and cause further increase in sediment transport in arid lands which in turn can adversely affect water quality. Hence, there is a strong need to predict the fate of sediments in order to provide measures for sound erosion control and water quality management. The presence of microtopography on hillslopes influences processes of runoff generation and erosion, which should be taken into account to achieve more accurate modelling results. This study presents a physically based mathematical model for erosion and sediment transport coupled to one-dimensional overland flow equations that simulate rainfall-runoff generation on the rill and interrill areas of a bare hillslope. Modelling effort at such a fine resolution considering the flow connection between interrill areas and rills is rarely verified. The developed model was applied on a set of data gathered from an experimental setup where a 650 cm×136 cm erosion flume was pre-formed with a longitudinal rill and interrill having a plane geometry and was equipped with a rainfall simulator that reproduces natural rainfall characteristics. The flume can be given both longitudinal and lateral slope directions. For calibration and validation, the model was applied on the experimental results obtained from the setup of the flume having 5% lateral and 10% longitudinal slope directions under rainfall intensities of 105 and 45 mm/h, respectively. Calibration showed that the model was able to produce good results based on the R2(0.84) and NSE(0.80) values. The model performance was further tested through validation which also produced good statistics(R2=0.83, NSE=0.72). Results in terms of the sedigraphs, cumulative mass curves and performance statistics suggest that the model can be a useful and an important step towards verifying and improving mathematical models of erosion and sediment transport. | Anya Catherine CARGUELLES MinJae JUNG Kristine Joy BMALLARI GiJung PAK Hafzullah AKSOY Levent M KAVVAS Ebru ERIS JaeYoung YOON YoungJoon LEE SeonHwa HONG | 2014 | Journal of Arid Land2014，6，6： | 3 |
| 5 | Early-onset gastric cancer:Learning lessons from the young显示文摘There is by no means a clear-cut pattern of mutations contributing to gastric cancers,and gastric cancer research can be hampered by the diversity of factors that can induce gastric cancer,such as Helicobacter pylori infection,diet,ageing and other environmental factors.Tumours are unquestionably riddled with genetic changes yet we are faced with an unsolvable puzzle with respect to a temporal relationship.It is postulated that inherited genetic factors may be more important in early-onset gastric cancer (EOGC) than in gastric cancers found in older patients as they have less exposure to environmental carcinogens.EOGC,therefore,could provide a key to unravelling the genetic changes in gastric carcinogenesis.Gastric cancers occurring in young patients provide an ideal background on which to try and uncover the initiating stages of gastric carcinogenesis.This review summarizes the literature regarding EOGC and also presents evidence that these cancers have a unique molecular-genetic phenotype,distinct from conventional gastric cancer. | Anya N Milne G Johan A Offerhaus | 2010 | World Journal of Gastrointestinal Oncology2010，2，2： | 3 |
| 6 | Human Umbilical Mesenchymal Stem Cells Promote Recovery After Ischemic Stroke显示文摘 | Yu-Ching Lin Tsui-Ling Ko Yang-Hsin Shih Maan-Yuh Anya Lin Tz-Win Fu Hsiao-Sheng Hsiao Jung-Yu C. Hsu Yu-Show Fu | 2011 | Stroke2011，，7： | 2 |
| 7 | Neuroprotective Effect of Intermittent Hypoxia on Iron-Induced Oxidative Injury in Rat Brain显示文摘 | Anya M.Y. Lin C.F. Chen L.T. Ho | 2002 | Experimental Neurology2002，，2： | 1 |
| 8 | Memory impairment correlates with increased S100B serum concentrations in patients with chronic schizophrenia显示文摘 | Anya Pedersen Markus Diedrich Florian Kaestner Katja Koelkebeck Patricia Ohrmann Gerald Ponath Frank Kipp Simone Abel Ansgar Siegmund Thomas Suslow Christof von Eiff Volker Arolt Matthias Rothermundt | 2008 | Progress in Neuropsychopharmacology & Biological Psychiatry2008，，： | 1 |
| 9 | Early‐onset gastric carcinomas display molecular characteristics distinct from gastric carcinomas occurring at a later age显示文摘 | RalphCarvalho Anya NAMilne Bastiaan Pvan Rees EricCaspers LuísCirnes CéuFigueiredo G Johan AOfferhaus Marian AJWeterman | 2004 | J Pathol2004，，1： | 1 |
| 10 | Innate im m unity conferred by Toll-like receptors 2 and 4 and mye?loid differentiation factor 88 expression is pivotal to monosodium urate monohydrate crystal in?duced inflammation显示文摘 | Peter S Ru LB Anya S | 2005 | Arthritis Rheum2005，52，9： | 1 |
| 11 | Genital prolapse in Port Harcourt,Nigeria显示文摘 | Ugboma HA Okpani AO Anya SE | 2004 | Niger J Med2004，13，2： | 1 |
| 12 | 医疗照护的改进:患者和照护者“点赞”才是真的好他们的观点对于所有成功的医疗改进都至关重要显示文摘提高医疗照护质量需要团队的努力,当团队中包括服务使用者及其照护者、家人和倡导者时,效果最佳。团队中的这些人员可根据个人应对疾病的经验,提供有利于健康的一手建议,或是提供医疗照护系统以外的相关生活技巧。提高医疗照护质量需要团队的努力,当团队中包括服务使用者及其照护者、家人和倡导者时,效果最佳。团队中的这些人员可根据个人应对疾病的经验,提供有利于健康的一手建议,或是提供医疗照护系统以外的相关生活技巧。 | Anya de Iongh Sibylle Erdmann 李俊(译) | 2018 | 英国医学杂志中文版2018，21，8： | 1 |
| 13 | Maternal deaths associated with cesarean section in Enugu , Nigeria 显示文摘 | Ozumba BC Anya SE | 2002 | Int J Gynecol Obstet2002，76，： | 1 |
| 14 | Studies of energy metabolism in the endoparasite Strongylurisbrevicatdata显示文摘 | Gabriel M Umezurike A Anya O | 1978 | Biochem Physiol1978，，： | 1 |
| 15 | Accidental incision of the fetus at caesarian section显示文摘 | Okaro JM Anya SE | 2004 | Niger J Med2004，13，1： | 1 |
| 16 | Escape of methane gas from the seabed along the West Spitsbergen continental margin显示文摘 | Westbrook Graham K. Thatcher Kate E. Rohling Eelco J. Piotrowski Alexander M. P?like Heiko Osborne Anne H. Nisbet Euan G. Minshull Tim A. Lanoisellé Mathias James Rachael H. Hühnerbach Veit Green Darryl Fisher Rebecca E. Crocker Anya J. Chab | 2009 | Geophysical Research Letters2009，，15： | 1 |
| 17 | Regeneration in a mass-tourism resort: The changing fortunes of Bugibba, Malta显示文摘 | Anya Chapman Janet Speake | 2010 | Tourism Management2010，，3： | 1 |
| 18 | Innate Immunity Conferred by Toll-like Receptors 2 and 4 and Myeloid Differentiation Factor 88 Expression Is Pivotal to Monosodium Urate Monohydrate Crystal- Induced Inflammation显示文摘 | Liu BR Peter S Anya S | 2005 | Arthritis Rheum2005，52，9： | 1 |
| 19 | Maternal deaths associated with cesarean section in Enugu,Nigeria显示文摘 | Ozmba BC Anya SE | 2002 | Int J Gynecol Obstet2002，76，： | 1 |
| 20 | Genital prolapse in Port Harcourt,Nigeria显示文摘 | UGBOMA H A OKPANI A O ANYA S E | 2004 | Niger J Med2004，13，2： | 1 |
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