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| 1 | Chemotherapy-induced intestinal inflammatory responses are mediated by exosome secretion of double-strand DNA via AIM2 inflammasome activation显示文摘化疗经常被知道导致严重的胃肠的道毒性,但是内在的机制仍然保持不清楚。这研究作为一个代表性的代理人认为广泛地应用的细胞毒素的代理人是 irinotecan (CPT-11 ) 并且证明治疗从说明混合物的限制剂量的肠的毒性的肠导致双海滨 DNA 的巨大的版本。明确地,通过 exosome 分泌物释放的 self-DNA 进入天生的有免疫力的房间的 cytosol 并且激活 AIM2 (在黑瘤 2 不在) inflammasome。这导致成熟 IL-1 和 IL-18 分泌物并且导致肠的 mucositis 和迟了发作的腹泻。有趣地,在 AIM2 缺乏的老鼠或由象镇静药那样的一个药理学禁止者,没有影响 CPT-11 的 anticancer 功效, AIM2 发信号的废除显著地减少导致药的腹泻的发生。这些调查结果提供化疗怎么触发引起肠的毒性的天生的有免疫力的回答的机械学的卓见,并且揭示维持反瘤效果,但是围绕联系不利煽动性的反应的新化疗政体。 | Lian, Qiaoshi Xu, Jun Yan, Shanshan Huang, Min Ding, Honghua Sun, Xiaoyu Bi, Aiwei Ding, Jian Sun, Bing Geng, Meiyu | 2017 | Cell Research2017，27，6： | 18 |
| 2 | Surface plasmonic effect and scattering effect of Au nanorods on the performance of polymer bulk heterojunction solar cells显示文摘The surface plasmonic effect and scattering effect of gold nanorods(AuNRs) on the performance of bulk heterojunction photovoltaic devices based on the blend of polythiophene and fullerene are investigated.AuNRs enhance the excitation since the plasmonic effect increases the electric field,mainly in the area near the interface between the active layer and AuNRs.The results show that the incident photo-to-electron conversion efficiency(IPCE) obviously increases for the device with a layer of gold nanorods,resulting from the plasmonic effect of AuNRs in the range of 500-670 nm and the scattering effect in the range of 370-410 nm.The power conversion efficiency(PCE) is increased by 7.6% due to the near field effect of the localized surface plasmons(LSP) of AuNRs and the scattering effect.The short circuit current density is also increased by 9.1% owing to the introduction of AuNRs.However,AuNRs can cause a little deterioration in open circuit voltage. | FANG Yi HOU YanBing LOU ZhiDong TENG Feng TANG AiWei HU YuFeng | 2013 | Science China(Technological Sciences)2013，56，8： | 4 |
| 3 | Retinol Binding Protein 4 Expression in Humans: Relationship to Insulin Resistance, Inflammation, and Response to Pioglitazone显示文摘 | Aiwei Yao-Borengasser Vijayalakshmi Varma Angela M. Bodles Neda Rasouli Bounleut Phanavanh Mi-Jeong Lee Tasha Starks Leslie M. Kern Horace J. Spencer Amir Adel Rashidi Robert E. McGehee Susan K. Fried Philip A. Kern | 2007 | The Journal of Clinical Endocrinology & Metabolism2007，，7： | 3 |
| 4 | Rational design of multinary copper chalcogenide nanocrystals for photocatalytic hydrogen evolution显示文摘Photocatalytic hydrogen evolution is one of the most promising ways to solve environmental problems and produce a sustainable energy source.To date,different types of photocatalysts have been developed and widely used in photocatalytic hydrogen evolution.Recently,multinary copper chalcogenides have attracted much attention and exhibited potential applications in photocatalytic hydrogen evolution due to their composition-tunable band gaps,diverse structures and environmental-benign characteristics.In this review,some progress on the synthesis and photocatalytic hydrogen evolution of multinary copper chalcogenide nanocrystals(NCs)was summarized.In particular,considerable attention was paid to the rational design and dimensional or structural regulation of multinary copper chalcogenide NCs.Importantly,the photocatalytic hydrogen evolution of multinary copper chalcogenide NCs were reviewed from the aspects of energy level structures,crystal facets,morphology as well as composition.Finally,the current challenges and future perspectives of copper chalcogenide were proposed. | Hao Fu Aiwei Tang | 2020 | Journal of Semiconductors2020，41，9： | 3 |
| 5 | Tunable crystal structure of Cu-Zn-Sn-S nanocrystals for improving photocatalytic hydrogen evolution enabled by copper element regulation显示文摘Hydrogen energy is a powerful and efficient energy resource,which can be produced by photocatalytic water split-ting.Among the photocatalysis,multinary copper-based chalcogenide semiconductor nanocrystals exhibit great potential due to their tunable crystal structures,adjustable optical band gap,eco-friendly,and abundant resources.In this paper,Cu-Zn-Sn-S(CZTS)nanocrystals with different Cu content have been synthesized by using the one-pot method.By regulating the surface ligands,the reaction temperature,and the Cu content,kesterite and hexagonal wurtzite CZTS nanocrystals were obtained.The critical factors for the controllable transition between two phases were discussed.Subsequently,a series of quatern-ary CZTS nanocrystals with different Cu content were used for photocatalytic hydrogen evolution.And their band gap,energy level structure,and charge transfer ability were compared comprehensively.As a result,the pure hexagonal wurtzite CZTS nano-crystals have exhibited an improved photocatalytic hydrogen evolution activity. | Zhe Yin Min Hu Jun Liu Hao Fu Zhijie Wang Aiwei Tang | 2022 | Journal of Semiconductors2022，43，3： | 2 |
| 6 | NUMERICAL SIMULATION OF SWIRLING FLOWS IN OXIDATION REACTORS FOR TiO_2 MANUFACTURE显示文摘The oxidation reactor plays a key role in producing rutile titanium dioxide (TiO2) from vapor-phase titanium tetrachloride (TiCl4) by employing a swirling flow operation for enhanced gas mixing. This work aims to understand the effect of reactor configuration on the 3-D swirling flow field using computational fluid dynamics (CFD) simulation. Con- sidering the anisotropic turbulence involved, the Reynolds stress model is applied to describe the complex swirling flow together with the cross-flow mixing of gases. The results show significant effect of the flow angle between the wall jet of air stream (representing TiCl4 in practice) and the axial direction on the initial flow field of cross-flow mixing, where 60o gives smooth profiles of axial velocity development while 90° may provide the fastest mixing between the jet and the axial bulk flow. The pipe shape for the reaction and developing zone, i.e., straight, expanding and shrinking, shows slight in- fluence on the hydrodynamics. | Yi Cheng Aiwei Ye Fei Liu Fei Wei | 2006 | China Particuology2006，4，3： | 2 |
| 7 | SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors显示文摘Muta nt isocitrate dehydrog en ase 1(mlDH1)drives tumorigenesis via produci ng on cometabolite R-2-hydroxyglutarate(R-2-HG)across various tumor types.However,mlDHl in hibitors appear only effective in hematological tumors.The therapeutic ben efit in solid tumors remains elusive,likely due to the complex tumor microenvironment.In this study,we discover that R-2-HG produced by IDH1-mutant tumor cells is preferentially imported into vascular endothelial cells and remodels mitochondrial respiration to promote tumor angiogenesis,conferring a therapeutic vulnerability in IDH1-mutant solid tumors.Mechanistically,SLC1 Alz a Na'-depe ndent glutamate tran sporter that is prefere ntially expressed in en dothelial cells,facilitates the in flux of R-2-HG from the tumor microenvironment into the endothelial cells as well as the intracellular trafficking of R-2-HG from cytoplasm to mitochondria.R-2-HG hijacks SLC1A1 to promote mitochondrial Na^(+)/Ca^(2+)exchange,which activates the mitochondrial respiratory chain and fuels vascular en dothelial cell migratio n in tumor an giogenesis.SLC1A1 deficiency in mice abolishes mlDHl-promoted tumor an giogenesis as well as the therapeutic benefit of mlDHl in hibitor in solid tumors.Moreover,we report that HH2301,a newly discovered mlDHl inhibitor,shows promising efficacy in treating IDH1-mutant cholangiocarcinoma in preclinical models.Together,we identify a new role of SLC1A1 as a gatekeeper of R-2-HG-mediated crosstalk between IDH1-mutant tumor cells and vascular en dothelial cells,and dem on strate the therapeutic potential of mlDHl in hibitors in treating IDH1-muta nt solid tumors via disrupting R-2-HG-promoted tumor angiogenesis. | Xiaomin Wang Ziqi Chen Jun Xu Shuai Tang Nan An Lei Jiang Yixiang Zhang Shaoying Zhang Qingli Zhang Yanyan Shen Shijie Chen Xiaojing Lan Ting Wang Linhui Zhai Siyuwei Cao Siqi Guo Yingluo Liu Aiwei Bi Yuehong Chen Xiameng Gai Yichen Duan Ying Zheng Yixian Fu Yize Li Liang Yuan Linjiang Tong Kun Mo Mingcheng Wang Shu-Hai Lin Minjia Tan Cheng Luo Yi Chen Jia Liu Qiansen Zhang Leping Li Min Huang | 2022 | Cell Research2022，32，7： | 2 |
| 8 | Eleetroluminescenee of cadmium selenium nanoerystals synthesized in aqueous solution显示文摘 | Gao Yinhao Liang Chunjun Tang Aiwei | 2007 | Journal of Luminescence2007，，： | 1 |
| 9 | Progress on the controllable synthesis of all-inorganic halide perovskite nanocrystals and their optoelectronic applications显示文摘In the past five years,all-inorganic metal halide perovskite(CsPbX3,X=Cl,Br,I)nanocrystals have been intensely studied due to their outstanding optical properties and facile synthesis,which endow them with potential optoelectronic applications.In order to optimize their physical and chemical properties,different strategies have been developed to realize the controllable synthesis of CsPbX3 nanocrystals.In this short review,we firstly present a comprehensive and detailed summary of existed synthesis strategies of CsPbX3 nanocrystals and their analogues.Then,we introduce the regulations of several reaction parameters and their effects on the morphologies of CsPbX3 nanocrystals.At the same time,we provide stability improvement methods and representative applications.Finally,we propose the current challenges and future perspectives of the promising materials. | Yi Yuan Aiwei Tang | 2020 | Journal of Semiconductors2020，41，1： | 1 |
| 10 | Insulin Resistance in African-American and Caucasian Women: Differences in Lipotoxicity, Adipokines, and Gene Expression in Adipose Tissue and Muscle显示文摘 | Latasha M. Smith Aiwei Yao-Borengasser Tasha Starks Mark Tripputi Philip A. Kern Neda Rasouli | 2010 | The Journal of Clinical Endocrinology & Metabolism2010，，9： | 1 |
| 11 | InSe/hBN/graphite heterostructure for high-performance 2D electronics and flexible electronics显示文摘Two-dimensional(2D)materials as channel materials provide a promising alternative route for future electronics and flexible electronics,but the device performance is affected by the quality of interface between the 2D-material channel and the gate dielectric.Here we demonstrate an indium selenide(lnSe)/hexagonal boron nitride(hBN)/graphite heterostructure as a 2D field-effect transistor(FET),with InSe as channel material,hBN as dielectric,and graphite as gate.The fabricated FETs feature high electron mobility up to 1,146 cm2·V^-1·s^-1 at room temperature and on/off ratio up to 1010 due to the atomically flat gate dielectric.Integrated digital inverters based on InSe/hBN/graphite heterostructures are constructed by local gating modulation and an ultrahigh voltage gain up to 93.4 is obtained.Taking advantages of the mechanical flexibility of these materials,we integrated the heterostructured InSe FET on a flexible substrate,exhibiting little modification of device performance at a high strain level of up to 2%.Such high-performance heterostructured device configuration based on 2D materials provides a new way for future electronics and flexible electronics. | Liangmei Wu Jinan Shi Zhang Zhou Jiahao Yan Aiwei Wang Ce Bian Jiajun Ma Ruisong Ma Hongtao Liu Jiancui Chen Yuan Huang Wu Zhou Lihong Bao Min Ouyang Sokrates T.Pantelides Hong-Jun Gao | 2020 | Nano Research2020，13，4： | 1 |
| 12 | Electrical bistability of copper (Ⅰ) sulfide nanocrystals blending with a semiconducting polymer显示文摘 | Tang Aiwei Teng Feng Qian Lei | | 0，，14： | 1 |
| 13 | Study and Analysis on Carbon Trade Market in China显示文摘 | Shanshan Wang Aiwei Wang Fanxi Meng | 2012 | China Agricultural University2012，，5： | 1 |
| 14 | eDNA Cloning and sequencing, gene expression, and immunolocalization of thrombomodulin in the sprague-dawley rat显示文摘 | Wang Junru Yao Aiwei Wang Jing yi | 1999 | DNA Research1999，6，1： | 1 |
| 15 | Research on Fault Diagnosis of Diesel Engine Based on Bis- pectrum Analysis and Genetic Neural Network显示文摘 | Feng Fuzhou Si Aiwei Zhang Hongxing | 2011 | Procedia Engineering2011，15，： | 1 |
| 16 | Matrix Metalloproteinase-9 Is Increased in Obese Subjects and Decreases in Response to Pioglitazone显示文摘 | Resat Unal Aiwei Y-B Vijayalakshmi Varma | 2010 | Clin Endocrinol Metab2010，95，7： | 1 |
| 17 | Theory,technology and practice of shale gas three-dimensional development:A case study of Fuling shale gas field in Sichuan Basin,SW China显示文摘In the Jiaoshiba block of the Fuling shale gas field,the employed reserves and recovery factor by primary well pattern are low,no obvious barrier is found in the development layer series,and layered development is difficult.Based on the understanding of the main factors controlling shale gas enrichment and high production,the theory and technology of shale gas three-dimensional development,such as fine description and modeling of shale gas reservoir,optimization of three-dimensional development strategy,highly efficient drilling with dense well pattern,precision fracturing and real-time control,are discussed.Three-dimensional development refers to the application of optimal and fast drilling and volume fracturing technologies,depending upon the sedimentary characteristics,reservoir characteristics and sweet spot distribution of shale gas,to form'artificial gas reservoir'in a multidimensional space,so as to maximize the employed reserves,recovery factor and yield rate of shale gas development.In the research on shale gas three-dimensional development,the geological+engineering sweet spot description is fundamental,the collaborative optimization of natural fractures and artificial fractures is critical,and the improvement of speed and efficiency in drilling and fracturing engineering is the guarantee.Through the implementation of three-dimensional development,the overall recovery factor in the Jiaoshiba block has increased from 12.6%to 23.3%,providing an important support for the continuous and stable production of the Fuling shale gas field. | SUN Huanquan CAI Xunyu HU Degao LU Zhiyong ZHAO Peirong ZHENG Aiwei LI Jiqing WANG Haitao | 2023 | Petroleum Exploration and Development2023，50，3： | 1 |
| 18 | Line tension at fluid membrane domain boundaries measured by micropipette aspiration显示文摘 | Aiwei T Johnson C Wang Z W | 2007 | Phys Rev Lett2007，98，20： | 1 |
| 19 | Characterization of nanoscale clusters fabricated by pulsed laser irradiation of thin Au films显示文摘 | Yi Fang Yanbing Hou Feng Teng Zhidong Lou Aiwei Tang Bo Zhang Lingchuan Meng Yu Ning Longfeng Lu | 2013 | Applied Surface Science2013，，： | 1 |
| 20 | cDNA cloning and sequencing,gene expression,and immunolocalization of thrombomodulin in the sprague-dawley rat显示文摘 | Junru W Aiwei Y Wang J Y | 1999 | DNA Res1999，6，： | 1 |
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