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| 1 | Inflammation and immunosuppression in severe acute pancreatitis显示文摘Acute pancreatitis(AP) is a common disease,which usually exists in its mild form.However,in a fifth of cases,the disease is severe,with local pancreatic complications or systemic organ dysfunction or both.Because the development of organ failure is the major cause of death in AP,early identification of patients likely to develop organ failure is important.AP is initiated by intracellular activation of pancreatic proenzymes and autodigestion of the pancreas.Destruction of the pancreatic parenchyma first induces an inflammatory reaction locally,but may lead to overwhelming systemic production of inflammatory mediators and early organ failure.Concomitantly,anti-inflammatory cytokines and specific cytokine inhibitors are produced.This anti-inflammatory reaction may overcompensate and inhibit the immune response,rendering the host at risk of systemic infection.At present,there is no specific treatment for AP.Increased understanding of the pathogenesis of systemic inflammation and development of organ dysfunction may provide us with drugs to ameliorate physiological disturbances. | Marja-Leena Kylnp Heikki Repo Pauli Antero Puolakkainen | 2010 | World Journal of Gastroenterology2010，16，23： | 97 |
| 2 | Immunogenetic characteristics of patients with autoimmune gastritis显示文摘AIM:To explore whether predisposition to autoimmune gastritis (AIG) is found in human leukocyte antigen (HLA), cytokine or killer cell immunoglobulin-like receptor (KIR) gene variations.METHODS: Twelve Finnish patients with autoimmunetype severe atrophy of the gastric corpus were included. The patients' serum was analyzed for pepsinogen-interleukin (IL)-1 gene cluster, IL-2, IL-4, IL-6, IL-10, IL-12, interferon γ, transforming growth factor β, and tumor necrosis factor α. Variation in KIR genes was also explored. The results were compared with prevalence of the polymorphisms in Finnish or European populations.RESULTS: All patients had pepsinogen-CONCLUSION: As explored with modern DNA-based methods, HLA-DRB1*04 and DQB1*03 alleles, but not HLA-B8-DRB1*03, may predispose to AIG. | Aino Mirjam Oksanen Katri Eerika Haimila Hilpi Iris Kaarina Rautelin Jukka Antero Partanen | 2010 | World Journal of Gastroenterology2010，16，3： | 8 |
| 3 | Frequency and Clinical Determinants of Poststroke Depression显示文摘 | Tarja Pohjasvaara Antero Leppavuori Irina Siira Risto Vataja Markku Kaste Timo Erkinjuntti | 1998 | Stroke: A Journal of Cerebral Circulation1998，，11： | 4 |
| 4 | The Hemodynamic and Adrenergic Effects of Perioperative Dexmedetomidine Infusion after Vascular Surgery显示文摘 | Pekka Talke Richard Chen Brian Thomas Anil Aggarwall Alexandru Gottlieb Per Thorborg Stephen Heard Albert Cheung Stanley Lee Son Antero Kallio | 2000 | Anesthesia & Analgesia2000，，4： | 3 |
| 5 | Inflammation in Alzheimer’s disease: Amyloid-β oligomers trigger innate immunity defence via pattern recognition receptors显示文摘 | Antero Salminen Johanna Ojala Anu Kauppinen Kai Kaarniranta Tiina Suuronen | 2009 | Progress in Neurobiology2009，，3： | 2 |
| 6 | Inflammation in Alzheimer’s disease: Amyloid-β oligomers trigger innate immunity defence via pattern recognition receptors显示文摘 | Antero Salminen Johanna Ojala Anu Kauppinen Kai Kaarniranta Tiina Suuronen | 2009 | Progress in Neurobiology2009，，3： | 2 |
| 7 | PREVENTION OF SYSTEMIC HYPERLACTATEMIA DURING SPLANCHNIC ISCHEMIA显示文摘 | Stephan M. Jakob Minna Merasto-Minkkinen Jyrki J. Tenhunen Antero Heino Esko Alhava Jukka Takala | 2000 | Shock2000，，2： | 1 |
| 8 | Inflammation in Alzheimer's disease : Amyloid-β oligomers trigger innate immunity defence via pattern recognition receptors 显示文摘 | Antero S Johanna O Anu K | 2009 | Prog Neurobio12009，87，3： | 1 |
| 9 | Landfill leachate treatment with sequencing batch reactor and membrane bioreactor显示文摘 | Niina Laitinen Antero Luonsi Jari Vilen | | 0，，1： | 1 |
| 10 | The Hemodynamic and Adrenergic Effects of Perioperative Dexmedetomidine Infusion after Vascular Surgery显示文摘 | Pekka Talke Richard Chen Brian Thomas Anil Aggarwall Alexandru Gottlieb Per Thorborg Stephen Heard Albert Cheung Stanley Lee Son Antero Kallio | 2000 | Anesthesia & Analgesia2000，，4： | 1 |
| 11 | Low plasma ghrelin concentration is an indicator of the metabolic syndrome 显示文摘 | Ukkola O Poykko SM Antero Kesaniemi Y | 2006 | Ann Med2006，38，4： | 1 |
| 12 | Determination of Forces and Linearized Parameters of Radial Active Magnetic Bearings by Finite Element Technique显示文摘 | Matti Antila Erkki Lantto Antero Arkkio | 1998 | IEEE Transactions on Magnetics1998，34，3： | 1 |
| 13 | Reference limits in occupational toxicology 显示文摘 | Antero Aitio | 1994 | Clin Chem1994，40，7： | 1 |
| 14 | Frequency and clinical determinants of post - stroke depression显示文摘 | Jcrja P Antero L Irina S | 1998 | Stroke1998，29，11： | 1 |
| 15 | Low plasma ghrelin concentration is an indicator of the metabolic syndrome 显示文摘 | Ukkola Poykko SM Antero KY | 2006 | Ann Med2006，38，4： | 1 |
| 16 | Activation of innate immunity system during aging:NF-KB signaling is the molecular culprit of inflamm-aging显示文摘 | Antero S Jail H Johanna O | 2008 | Ageing Res Rev2008，7，2： | 1 |
| 17 | Inductance Model for Coupling Finite Element Analysis With Circuit Simulation 显示文摘 | Sami Kanerva Slavomir Seman Antero Arkkio | 2005 | IEEE Transactions on Magnetics2005，41，5： | 1 |
| 18 | Heat Transfer and Hydrodynamics of Falling Films 显示文摘 | Martti Harkonen Ari Aula Antero Aittomaki | 1994 | Acta Polytechnica Scandinavica Mechanical Engineering1994，15，： | 1 |
| 19 | InflammationinAlzheimersdisease:Amyloid-βoligomerstriggerinnateimmunitydefenceviapatternrecognitionreceptors显示文摘 | ANTEROS JOHANNAO ANUK etal | 2009 | ProgNeurobiol2009，87，3： | 1 |
| 20 | Frequency and clinical determinants of post-storke depression显示文摘 | Tcrja P Antero L Irina S | 1998 | Stroke1998，29，11： | 1 |
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