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224篇 您的检索式:作者名="ALAIN L"
    题名 作者 年代 出处 被引量
1通过手机进行健康干预报告的指南:移动医疗证据报告和评估检查表显示文摘为提升移动医疗(mHealfh)干预报告的完整性,WH0mHealth技术证据评审小组开发了mHealth证据报告和评估(mERA)检查表。该mERA开发过程包括成立专家组,提出合适的路径,召集全球专家评审小组以研发检查表,并进行小规模测试。制定这些标准的指导原则是以最少的信息集合来定义mHealth干预是什么(内容),在哪儿应用(环境),如何应用(技术特性),以便支持干预的可重复性。该文档由16个选项表构成,附带各项内容的详细解释和说明,以及说明性的报告范例。通过广泛征求意见,我们希望该指南的应用可规范mHealth证据报告的质量,间接提升mHealth证据的质量。Smisha Agarwal Amnesty E LeFevre Jaime Lee Kelly L'Engle Garrett Mehl Chaitali Sinha Alain Labriquel 沈锡宾(译) 涂宏钢(校) 2016英国医学杂志中文版2016,19,11:6
2Mucosal healing and deep remission: What does it mean?显示文摘The use of specific terms under different meanings and varying definitions has always been a source of confusion in science.When we point our efforts towards an evidence based medicine for inflammatory bowel diseases(IBD)the same is true:Terms such as'mucosal healing'or'deep remission'as endpoints in clinical trials or treatment goals in daily patient care may contribute to misconceptions if meanings change over time or definitions are altered.It appears to be useful to first have a look at the development of terms and their definitions,to assess their intrinsic and context-independent problems and then to analyze the different relevance in present-day clinical studies and trials.The purpose of such an attempt would be to gain clearer insights into the true impact of the clinical findings behind the terms.It may also lead to a better defined use of those terms for future studies.The terms'mucosal healing'and'deep remission'have been introduced in recent years as new therapeutic targets in the treatment of IBD patients.Several clinical trials,cohort studies or inception cohorts provided data that the long term disease course is better,when mucosal healing is achieved.However,it is still unclear whether continued or increased therapeutic measures will aid or improve mucosal healing for patients in clinical remission.Clinical trials are under way to answer this question.Attention should be paid to clearly address what levels of IBD activity are looked at.In the present review article authors aim to summarize the current evidence available on mucosal healing and deep remission and try to highlight their value and position in the everyday decision making for gastroenterologists.Gerhard Rogler Stephan Vavricka Alain Schoepfer Peter L Lakatos 2013World Journal of Gastroenterology2013,19,43:4
3ENETS Consensus Guidelines for the Management of Patients with Digestive Neuroendocrine Neoplasms: Functional Pancreatic Endocrine Tumor Syndromes显示文摘Jensen Robert T Cadiot Guillaume Brandi Maria L De Herder Wouter W Kaltsas Gregory Komminoth Paul Scoazec Jean-yves Salazar Ramon Sauvanet Alain Kianmanesh Reza 2012Neuroendocrinology2012,,2:3
4The equilibrium stability for a smooth and discontinuous oscillator with dry friction显示文摘In this paper,we investigate the equilibrium stability of a Filippov-type system having multiple stick regions based upon a smooth and discontinuous(SD) oscillator with dry friction.The sets of equilibrium states of the system are analyzed together with Coulomb friction conditions in both( f_n,f_s) and(x,˙x) planes.In the stability analysis,Lyapunov functions are constructed to derive the instability for the equilibrium set of the hyperbolic type and La Salle's invariance principle is employed to obtain the stability of the nonhyperbolic type.Analysis demonstrates the existence of a thick stable manifold and the interior stability of the hyperbolic equilibrium set due to the attractive sliding mode of the Filippov property,and also shows that the unstable manifolds of the hyperbolic-type are that of the endpoints with their saddle property.Numerical calculations show a good agreement with the theoretical analysis and an excellent efficien y of the approach for equilibrium states in this particular Filippov system.Furthermore,the equilibrium bifurcations are presented to demonstrate the transition between the smooth and the discontinuous regimes.Zhi-Xin Li Qing-Jie Cao Alain Léger 2016Acta Mechanica Sinica2016,32,2:2
5Natural History of Intraductal Papillary Mucinous Tumors of the Pancreas: Actuarial Risk of Malignancy显示文摘Philippe Lévy Vincent Jouannaud Dermot O’Toole Anne Couvelard Marie Pierre Vullierme Laurent Palazzo Alain Aubert Philippe Ponsot Alain Sauvanet Frédérique Maire Olivia Hentic Pascal Hammel Philippe Ruszniewski 2006Clinical Gastroenterology and Hepatology2006,,4:2
6Soluble CD40 ligand in prediction of acute severe pancreatitis显示文摘瞄准:在胰腺炎严厉估计可溶的 CD40L (sCD40L ) 的早可预测性。方法:在 2000 年 2 月和 2003 年 2 月之间,有尖锐胰腺炎的 279 个连续病人有希望地在我们的学习被注册。在这份报告, 40 个病人与温和并且有严重胰腺炎的 40 个病人随机被学习。sCD40L 集中被测量在承认以后的 48 个小时。结果:sCD40L 层次显著地更高在在严重胰腺炎的承认以后的 48 个小时比在温和胰腺炎。用 1000 的截止,检测疾病的一堂严重功课的 sCD40L 的 pg/L,敏感和特性为 CRP 与 72% 和 81% 相比分别地是 78% 和 62% 。发现那 CRP 的逻辑回归分析统计上是唯一的能检测疾病的一堂严重功课的重要标记。结论:这些调查结果显示 CRP 仍然是一个珍贵标记而 sCD40L 层次应该在进一步的研究被估计,决定尖锐胰腺炎的严厉和预后。Jean Louis Frossard Philippe Morel Brenda Kwak Catherine Pastor Thierry Berney Léo Buhler Alain Von Laufen Sandrine Demulder Francois Mach 2006World Journal of Gastroenterology2006,12,10:2
7Role of endoscopic ultrasound in the screening and follow-up of high-risk individuals for familial pancreatic cancer显示文摘Managing familial pancreatic cancer(FPC)is challenging for gastroenterologists,surgeons and oncologists.High-risk individuals(HRI)for pancreatic cancer(PC)(FPC or with germline mutations)are a heterogeneous group of subjects with a theoretical lifetime cumulative risk of PC over 5%.Screening is mainly based on annual magnetic resonance imaging(MRI)and endoscopic ultrasound(EUS).The goal of screening is to identify early-stage operable cancers or high-risk precancerous lesions(pancreatic intraepithelial neoplasia or intraductal papillary mucinous neoplasms with high-grade dysplasia).In the literature,target lesions are identified in 2%-5%of HRI who undergo screening.EUS appears to provide better identification of small solid lesions(0%-46%of HRI)and chronicpancreatitis-like parenchymal changes(14%-77%of HRI),while MRI is probably the best modality to identify small cystic lesions(13%-49%of HRI).There are no specific studies in HRI on the use of contrast-enhanced harmonic EUS.EUS can also be used to obtain tissue samples.Nevertheless,there is still limited evidence on the accuracy of imaging procedures used for screening or agreement on which patients to treat.The cost-effectiveness of screening is also unclear.Certain new EUS-related techniques,such as searching for DNA abnormalities or protein markers in pancreatic fluid,appear to be promising.Diane Lorenzo Vinciane Rebours Frédérique Maire Maxime Palazzo Jean-Michel Gonzalez Marie-Pierre Vullierme Alain Aubert Pascal Hammel Philippe Lévy Louis de Mestier 2019World Journal of Gastroenterology2019,25,34:2
8Codon usage and gene function are related in sequences of Arabidopsis thaliana 显示文摘Helene C Fred6rique L Michel C Alain H 1998Gene1998,209,:1
9Cu planarization in electrochemical mechanical planarization 显示文摘FENG Q L TIAN B D ALAIN D 2006Journal of the Electrochemical Society2006,153,6:1
10Effect of neurotropin on cerebral edema,calcium and other elements in mice subarachnoidally injected with carrageenan显示文摘Pierre S Alain K L Stijn V L 1995Euro J Pharmacology1995,274,13:1
11Analog sensor design proposal for laser Doppler velocimetry 显示文摘Alain L D Guy P Jean C V 2004IEEE Sensors Journal2004,4,2:1
12Quality changes during the frozen storage of sea bass(Dicentrarchus labrax) muscle after pressure shift freezing and pressure assisted thawing显示文摘Valeria T Marie de L Alain Le-B 2010Innovative Food Science & Emerging Technologies2010,11,4:1
13Coupling of Organic Halides with Carbonyl Compounds Promoteds by SmI2 ,the Kagan Reagent 显示文摘ALAIN K ANNE M L 1999Chem Rew1999,99,:1
14Non-contact handling in microassembly: acoustical levitation 显示文摘Vincent V Pierre L Alain D 2005Precision Engineering2005,29,4:1
15Variability estimation of urban wastewater biodegradable fractions by respirometry显示文摘Fabienne Lagarde Marie-Hélène Tusseau-Vuillemin Paul Lessard Alain Héduit Fran?ois Dutrop Jean-Marie Mouchel 2005Water Research2005,,19:1
16Quality changes during the frozen storage of sea bass (Dicentrarchus labrax) muscle after pressure shift freezing and pressure assisted thawing 显示文摘Valeria T Marie D L Alain L 2010Innovative Food Science and Emerging Technologies2010,11,4:1
17Super/ subcritical fluid chromatography chiral separations with macrocyclic glycopeptide stationary phases显示文摘Ying L Alain B Clifford R 2002J Chromatogr A2002,978,:1
18Early and lateonset ventilator associated pneumonia acquired in the intensive careunit:comparison of risk factors显示文摘Marine G Alain L Bernard A 0,,01:1
19Analog sensor design proposal for laser doppler velocimetry显示文摘ALAIN L D GUY P JEAN C V 2004IEEE Sensors Journal2004,4,2:1
20RC two-way slabs strengthened with CFRP strips:experimental study and a limit analysis approach显示文摘 GILLES F ALAIN E 2003Composite Structures2003,60,4:1
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